| Definition | Mycobacterium sp. MCS chromosome, complete genome. |
|---|---|
| Accession | NC_008146 |
| Length | 5,705,448 |
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The map label for this gene is yohF [C]
Identifier: 108801377
GI number: 108801377
Start: 4695404
End: 4696192
Strand: Reverse
Name: yohF [C]
Synonym: Mmcs_4414
Alternate gene names: 108801377
Gene position: 4696192-4695404 (Counterclockwise)
Preceding gene: 108801388
Following gene: 108801376
Centisome position: 82.31
GC content: 66.67
Gene sequence:
>789_bases ATGGCGCTGGAGCAGTTCGATCTCACCGGGCAGGTCGCGATCGTGACCGGAGCGGGCAAGGGAGTCGGTCAGGGCATCGC GCAGGTGCTGGCGGAGGCAGGCGCTGCGGTCGTCGGTACTGCGCGCACAGAGTCTGATATCGCCGCGACGATTTCGGGAA TCGAGCGGGCAGGCGGCAAGGGTGTCGCGGTTGTCGCCGATGCCATGAGCCGACCGGACGGGGAGCGAGTGGTGGCGGCG GCCATGGAGAACTTCGGCCGTGTCGACATCCTGGTCAACAATGTCGGGGGCTCGACGTACGCGCGGTTCCTCGACATCAC CGACGAGGATTTCCGGCACACTTTCGACTGGTGTGTGACGTCGGCCTTCATCATGAGCCAGCTGACCGCGCGGCACATGA TCGAGGCGGGACGCGGATCGATCATCAACATCTCATCCGGGTCGGCCCGGTTCGGCATCCGGGCGCTGGCCGCCTACTGC ACCGCCAAGGGCGGACTCGAAGCGCTCACGCGCGCGATGGCGCAGGAGTTGGCGCCCAAGATCCGGGTGAACGCCATCGC GCTGGGATCCTTTGCGACCGAGGGCCTGCAGGGCAGTCTGGACATGATGCCGGGCTCGCTGGAGAAGATGAACGCGGCGA CGCCGCTACGCCGCCTCGGCGACGTCGCCGATCTCGGCCGGCTCTGTGTCTACCTGTCCACCCGCGACTGTTACGCCACG AACGCGATCTTCCACGTGGACGGCGGCATCGAGTCCAACAACTCGCCCCTGCCCATCCCCGACTACTGA
Upstream 100 bases:
>100_bases TCCGGGCCAGTGCGTCTCACTTGGCTCTTTGTGGGATTTCGTTGACGTGAGTCAGGGTGAGCCGTTTAGATGAGGACTGT TCCCGACGGGGAGGATCGCC
Downstream 100 bases:
>100_bases GCAGGAACGGAGCGCGGCAATGCGCAGAGTGGTCCAGTTCTCCACCGGTAACGTCGGCAGGCATTCACTGGCCGCCGTCA TCGGAAGACCCGATCTGAAG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: ORFC [H]
Number of amino acids: Translated: 262; Mature: 261
Protein sequence:
>262_residues MALEQFDLTGQVAIVTGAGKGVGQGIAQVLAEAGAAVVGTARTESDIAATISGIERAGGKGVAVVADAMSRPDGERVVAA AMENFGRVDILVNNVGGSTYARFLDITDEDFRHTFDWCVTSAFIMSQLTARHMIEAGRGSIINISSGSARFGIRALAAYC TAKGGLEALTRAMAQELAPKIRVNAIALGSFATEGLQGSLDMMPGSLEKMNAATPLRRLGDVADLGRLCVYLSTRDCYAT NAIFHVDGGIESNNSPLPIPDY
Sequences:
>Translated_262_residues MALEQFDLTGQVAIVTGAGKGVGQGIAQVLAEAGAAVVGTARTESDIAATISGIERAGGKGVAVVADAMSRPDGERVVAA AMENFGRVDILVNNVGGSTYARFLDITDEDFRHTFDWCVTSAFIMSQLTARHMIEAGRGSIINISSGSARFGIRALAAYC TAKGGLEALTRAMAQELAPKIRVNAIALGSFATEGLQGSLDMMPGSLEKMNAATPLRRLGDVADLGRLCVYLSTRDCYAT NAIFHVDGGIESNNSPLPIPDY >Mature_261_residues ALEQFDLTGQVAIVTGAGKGVGQGIAQVLAEAGAAVVGTARTESDIAATISGIERAGGKGVAVVADAMSRPDGERVVAAA MENFGRVDILVNNVGGSTYARFLDITDEDFRHTFDWCVTSAFIMSQLTARHMIEAGRGSIINISSGSARFGIRALAAYCT AKGGLEALTRAMAQELAPKIRVNAIALGSFATEGLQGSLDMMPGSLEKMNAATPLRRLGDVADLGRLCVYLSTRDCYATN AIFHVDGGIESNNSPLPIPDY
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=33.9920948616601, Blast_Score=111, Evalue=5e-25, Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=31.4516129032258, Blast_Score=101, Evalue=8e-22, Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=31.2757201646091, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI10190704, Length=262, Percent_Identity=29.3893129770992, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI4504505, Length=255, Percent_Identity=31.3725490196078, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=34.7150259067358, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=29.4820717131474, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI4557649, Length=174, Percent_Identity=32.183908045977, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI126723191, Length=195, Percent_Identity=31.2820512820513, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=28.099173553719, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI59889578, Length=212, Percent_Identity=27.3584905660377, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI19923817, Length=270, Percent_Identity=25.5555555555556, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=31.0077519379845, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=28.8461538461538, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=27.2277227722772, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI210032110, Length=168, Percent_Identity=26.1904761904762, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI7705855, Length=175, Percent_Identity=29.1428571428571, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI83715985, Length=257, Percent_Identity=29.1828793774319, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI40254986, Length=188, Percent_Identity=27.6595744680851, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI40807363, Length=158, Percent_Identity=29.1139240506329, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=35.7723577235772, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=35.0806451612903, Blast_Score=112, Evalue=4e-26, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=37.007874015748, Blast_Score=108, Evalue=2e-25, Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=33.4661354581673, Blast_Score=108, Evalue=5e-25, Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=34.136546184739, Blast_Score=107, Evalue=7e-25, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=28.7449392712551, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=32.2834645669291, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=29.9595141700405, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=30.7086614173228, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=28.1124497991968, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=24.2798353909465, Blast_Score=64, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=33.0677290836653, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=29.6442687747036, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=30.3643724696356, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=27.2, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17568967, Length=224, Percent_Identity=33.4821428571429, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=29.6153846153846, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560150, Length=245, Percent_Identity=29.3877551020408, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=28.4615384615385, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=25.9398496240602, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17560332, Length=195, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=28.6259541984733, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17562990, Length=244, Percent_Identity=29.5081967213115, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=29.6747967479675, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=27.1255060728745, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17536651, Length=271, Percent_Identity=26.9372693726937, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=27.6422764227642, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17560220, Length=248, Percent_Identity=27.0161290322581, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=26.9662921348315, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562906, Length=247, Percent_Identity=26.7206477732794, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17538480, Length=195, Percent_Identity=31.7948717948718, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=28.3524904214559, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI193203115, Length=171, Percent_Identity=28.6549707602339, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17564282, Length=168, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=28.3018867924528, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI193203117, Length=172, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17551412, Length=199, Percent_Identity=31.6582914572864, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562904, Length=248, Percent_Identity=27.4193548387097, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17538486, Length=198, Percent_Identity=30.3030303030303, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=29.4573643410853, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17555612, Length=212, Percent_Identity=33.0188679245283, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=27.6515151515151, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17561272, Length=256, Percent_Identity=28.90625, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI71982365, Length=192, Percent_Identity=27.6041666666667, Blast_Score=64, Evalue=7e-11, Organism=Caenorhabditis elegans, GI71997099, Length=192, Percent_Identity=32.2916666666667, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=253, Percent_Identity=30.0395256916996, Blast_Score=90, Evalue=3e-19, Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=29.9212598425197, Blast_Score=80, Evalue=4e-16, Organism=Drosophila melanogaster, GI23397609, Length=260, Percent_Identity=30, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=31.7073170731707, Blast_Score=97, Evalue=8e-21, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=31.3253012048193, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI24640492, Length=184, Percent_Identity=28.2608695652174, Blast_Score=85, Evalue=6e-17, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=28.8617886178862, Blast_Score=84, Evalue=8e-17, Organism=Drosophila melanogaster, GI21355319, Length=237, Percent_Identity=29.1139240506329, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=28.4, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI18859837, Length=178, Percent_Identity=35.3932584269663, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=25.7936507936508, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI281364892, Length=175, Percent_Identity=29.7142857142857, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI24580925, Length=200, Percent_Identity=30, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=26.6932270916335, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI21357673, Length=209, Percent_Identity=29.6650717703349, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI221510726, Length=171, Percent_Identity=28.6549707602339, Blast_Score=64, Evalue=9e-11, Organism=Drosophila melanogaster, GI17737361, Length=235, Percent_Identity=28.936170212766, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 27332; Mature: 27201
Theoretical pI: Translated: 4.92; Mature: 4.92
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 3.4 %Met (Translated Protein) 5.0 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 4.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MALEQFDLTGQVAIVTGAGKGVGQGIAQVLAEAGAAVVGTARTESDIAATISGIERAGGK CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCC GVAVVADAMSRPDGERVVAAAMENFGRVDILVNNVGGSTYARFLDITDEDFRHTFDWCVT CEEEEEHHHCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEHHEECCCCHHHHHHHHHHHH SAFIMSQLTARHMIEAGRGSIINISSGSARFGIRALAAYCTAKGGLEALTRAMAQELAPK HHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC IRVNAIALGSFATEGLQGSLDMMPGSLEKMNAATPLRRLGDVADLGRLCVYLSTRDCYAT EEEEEEEECCHHHCCCCCCHHCCCCCHHHHHHCCHHHHHCCHHHHHHEEEEEECCCCEEC NAIFHVDGGIESNNSPLPIPDY CCEEEECCCCCCCCCCCCCCCC >Mature Secondary Structure ALEQFDLTGQVAIVTGAGKGVGQGIAQVLAEAGAAVVGTARTESDIAATISGIERAGGK CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCC GVAVVADAMSRPDGERVVAAAMENFGRVDILVNNVGGSTYARFLDITDEDFRHTFDWCVT CEEEEEHHHCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEHHEECCCCHHHHHHHHHHHH SAFIMSQLTARHMIEAGRGSIINISSGSARFGIRALAAYCTAKGGLEALTRAMAQELAPK HHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC IRVNAIALGSFATEGLQGSLDMMPGSLEKMNAATPLRRLGDVADLGRLCVYLSTRDCYAT EEEEEEEECCHHHCCCCCCHHCCCCCHHHHHHCCHHHHHCCHHHHHHEEEEEECCCCEEC NAIFHVDGGIESNNSPLPIPDY CCEEEECCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8868443 [H]