| Definition | Mycobacterium sp. MCS chromosome, complete genome. |
|---|---|
| Accession | NC_008146 |
| Length | 5,705,448 |
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The map label for this gene is fabG [H]
Identifier: 108801370
GI number: 108801370
Start: 4687224
End: 4688069
Strand: Reverse
Name: fabG [H]
Synonym: Mmcs_4407
Alternate gene names: 108801370
Gene position: 4688069-4687224 (Counterclockwise)
Preceding gene: 108801376
Following gene: 108801369
Centisome position: 82.17
GC content: 69.5
Gene sequence:
>846_bases ATGACTGAGCCGCTGAACCTCGAGGGCCGGACCGTCGTCGTCTCCGGTGCCGGTGGCGGGGGTATCGGGACCACGGTCAC CGAACTGGCGGCCACCGCGGGGGCGACCGTCGTCGCGGTCAGCCGCAACCAGGACAACCTCGACCAGCACGTCGGGCCGC TGATCGCCAAGGGTCTGCCGGTCGTCACGGTCGCGGCCGACGCGTCGACCGACGAGGGCATCGCCCGTGTCCTCGGTGAG GCGCGGCGCGCCGACGGCGACCTCTACGGGTTGGTCAACGTCGCCGGCGGCGCCGCACCCGCGACGTGGATGCCCTCGAC CCGGGTCACCCGCGACGATTGGCGGGCGCTGTTCACCGCCAACCTCGAGACCGCCTTCTTCATGAGCCAGGCCGTCGCCG CCGAGATCCGGTCGAACGGGCACAAGGGGTCGATCGTCTCGGTGTCGTCGATCAGCGGGATGAACACCGCGCCGTTCCAC ATCGCCTACGGGACAGCCAAAGCCGCGGTGGTCGCGATGACCCGCACCATGGCCGTCGAACTGGCGCTCGACGGGATCCG CGTCAACGCCGTCGCCCCCGGCGTCACCGAGACCGCCGCCTCGGCGACCTATGTCGACCAGGATCCGGACCGCGACCGCA CCGCGATCGCGATGGGCCGCCGCGGAACGCCGGTCGAACAGGCGAACGCGATCCTGTTCCTGCTCTCGGACATGTCGAGC TACATCACCGGCCAGACGCTTCTGGTCGACGGTGGCCTCGACCTCAAGTGGACGCATCTGGGCGCCGACAACACGTCGTT GTTCCTCAAGGACGAGAACTTCCGCAGCTCCATCAGCCGGTTCTGA
Upstream 100 bases:
>100_bases CGCGGCGCATCAAAGGACCCTTGACGGCCGGATAACCCCTGCGGAATAGTGTTCTGCAATATGCAGAGCACCGTATGTCG TCCGGACAAATGGGCCCACC
Downstream 100 bases:
>100_bases GAGTCCGTTTTGTTGTGAAAGGACGCACTAGTGACCCATACCGAATCCGACCTCGACGCGGCGATCGAGGTCGAAGCCGA TGCGGACGACTCGACGGGTG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 281; Mature: 280
Protein sequence:
>281_residues MTEPLNLEGRTVVVSGAGGGGIGTTVTELAATAGATVVAVSRNQDNLDQHVGPLIAKGLPVVTVAADASTDEGIARVLGE ARRADGDLYGLVNVAGGAAPATWMPSTRVTRDDWRALFTANLETAFFMSQAVAAEIRSNGHKGSIVSVSSISGMNTAPFH IAYGTAKAAVVAMTRTMAVELALDGIRVNAVAPGVTETAASATYVDQDPDRDRTAIAMGRRGTPVEQANAILFLLSDMSS YITGQTLLVDGGLDLKWTHLGADNTSLFLKDENFRSSISRF
Sequences:
>Translated_281_residues MTEPLNLEGRTVVVSGAGGGGIGTTVTELAATAGATVVAVSRNQDNLDQHVGPLIAKGLPVVTVAADASTDEGIARVLGE ARRADGDLYGLVNVAGGAAPATWMPSTRVTRDDWRALFTANLETAFFMSQAVAAEIRSNGHKGSIVSVSSISGMNTAPFH IAYGTAKAAVVAMTRTMAVELALDGIRVNAVAPGVTETAASATYVDQDPDRDRTAIAMGRRGTPVEQANAILFLLSDMSS YITGQTLLVDGGLDLKWTHLGADNTSLFLKDENFRSSISRF >Mature_280_residues TEPLNLEGRTVVVSGAGGGGIGTTVTELAATAGATVVAVSRNQDNLDQHVGPLIAKGLPVVTVAADASTDEGIARVLGEA RRADGDLYGLVNVAGGAAPATWMPSTRVTRDDWRALFTANLETAFFMSQAVAAEIRSNGHKGSIVSVSSISGMNTAPFHI AYGTAKAAVVAMTRTMAVELALDGIRVNAVAPGVTETAASATYVDQDPDRDRTAIAMGRRGTPVEQANAILFLLSDMSSY ITGQTLLVDGGLDLKWTHLGADNTSLFLKDENFRSSISRF
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=234, Percent_Identity=33.7606837606838, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=39.1304347826087, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=31.0606060606061, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=32.258064516129, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI126723750, Length=235, Percent_Identity=28.0851063829787, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=31.9327731092437, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=29.3172690763052, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI66933014, Length=232, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI109715829, Length=234, Percent_Identity=26.9230769230769, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=27.6, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=28.0172413793103, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=31.4432989690722, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4503301, Length=231, Percent_Identity=24.6753246753247, Blast_Score=72, Evalue=8e-13, Organism=Homo sapiens, GI126723191, Length=171, Percent_Identity=32.1637426900585, Blast_Score=70, Evalue=2e-12, Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=32.1285140562249, Blast_Score=102, Evalue=4e-23, Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=32.8185328185328, Blast_Score=99, Evalue=4e-22, Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=32.4110671936759, Blast_Score=99, Evalue=4e-22, Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=31.2977099236641, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1788459, Length=166, Percent_Identity=36.7469879518072, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=30.8300395256917, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=28.1853281853282, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=30.8641975308642, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1789378, Length=263, Percent_Identity=32.319391634981, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=27.3809523809524, Blast_Score=69, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=34.7826086956522, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17555706, Length=262, Percent_Identity=33.969465648855, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=34, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=32.5757575757576, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=28.4584980237154, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=33.6032388663968, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=30.7116104868914, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=30.9433962264151, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=31.4176245210728, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=31.0861423220974, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=32.8063241106719, Blast_Score=94, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=30.3030303030303, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=30.9433962264151, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=32, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=29.0566037735849, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=29.8892988929889, Blast_Score=88, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=30.6818181818182, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=29.3893129770992, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=29.4776119402985, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=30.1526717557252, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=29.1666666666667, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=29.4339622641509, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=27.0992366412214, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17538182, Length=261, Percent_Identity=26.0536398467433, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17544670, Length=273, Percent_Identity=26.7399267399267, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17561272, Length=114, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17508651, Length=153, Percent_Identity=30.718954248366, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=266, Percent_Identity=27.4436090225564, Blast_Score=78, Evalue=2e-15, Organism=Drosophila melanogaster, GI21357041, Length=259, Percent_Identity=33.2046332046332, Blast_Score=104, Evalue=8e-23, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=31.6, Blast_Score=103, Evalue=2e-22, Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=32.6848249027237, Blast_Score=101, Evalue=7e-22, Organism=Drosophila melanogaster, GI24644337, Length=234, Percent_Identity=34.6153846153846, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=32.295719844358, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=31.9230769230769, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=31.640625, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=31.0077519379845, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=28.0632411067194, Blast_Score=68, Evalue=8e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 29224; Mature: 29093
Theoretical pI: Translated: 4.91; Mature: 4.91
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTEPLNLEGRTVVVSGAGGGGIGTTVTELAATAGATVVAVSRNQDNLDQHVGPLIAKGLP CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCC VVTVAADASTDEGIARVLGEARRADGDLYGLVNVAGGAAPATWMPSTRVTRDDWRALFTA EEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHEEEEC NLETAFFMSQAVAAEIRSNGHKGSIVSVSSISGMNTAPFHIAYGTAKAAVVAMTRTMAVE CCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHEEEE LALDGIRVNAVAPGVTETAASATYVDQDPDRDRTAIAMGRRGTPVEQANAILFLLSDMSS EEECCEEEEEECCCCCHHHCCCEECCCCCCCCCEEEEECCCCCCHHHCCEEEEEEHHHHH YITGQTLLVDGGLDLKWTHLGADNTSLFLKDENFRSSISRF HHCCCEEEEECCCCEEEEEECCCCCEEEEECCCHHHHHHCC >Mature Secondary Structure TEPLNLEGRTVVVSGAGGGGIGTTVTELAATAGATVVAVSRNQDNLDQHVGPLIAKGLP CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCC VVTVAADASTDEGIARVLGEARRADGDLYGLVNVAGGAAPATWMPSTRVTRDDWRALFTA EEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHEEEEC NLETAFFMSQAVAAEIRSNGHKGSIVSVSSISGMNTAPFHIAYGTAKAAVVAMTRTMAVE CCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHEEEE LALDGIRVNAVAPGVTETAASATYVDQDPDRDRTAIAMGRRGTPVEQANAILFLLSDMSS EEECCEEEEEECCCCCHHHCCCEECCCCCCCCCEEEEECCCCCCHHHCCEEEEEEHHHHH YITGQTLLVDGGLDLKWTHLGADNTSLFLKDENFRSSISRF HHCCCEEEEECCCCEEEEEECCCCCEEEEECCCHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]