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The map label for this gene is thcR [H]

Identifier: 108801308

GI number: 108801308

Start: 4620534

End: 4621580

Strand: Reverse

Name: thcR [H]

Synonym: Mmcs_4344

Alternate gene names: 108801308

Gene position: 4621580-4620534 (Counterclockwise)

Preceding gene: 108801312

Following gene: 108801306

Centisome position: 81.0

GC content: 70.68

Gene sequence:

>1047_bases
GTGAGCACCAATCCGGGGGTTCAGCCTCAGCCCCGCACTGCGTCACCTGCAGAGGTACCTCCCATAGCAAGACATCTCGA
CTCCCTTGGCGTCCTGGCACGGACCCAGGTCAAGATCATCGATTCCGACGAGGCGGCGGCGTTCCTCGACGACGCCTACG
GCTCCCGCCTGCGGTTGTCGCGGCTGGCGAATCCGACCGGCGGCCCGGTGCTGACCTACAGCCGTCACGACGCCGGCTCC
TTCACGATCGACGACATGGCGATGGCCGGCGGGTTCACCGCGTCACCCGACCCGCTGCACAAGGTGCTCGCGGTGTGGGC
GAACCGGGGCCGGATCGCAGGCCGGTGCGCCGGTATCGGCGGCCTGGCCCGCGCGGGCGAGGTCGCGCTGATGGCCCAGC
CGGACCTCCCGCACGATGCCGAAGCCGAGGACGTCGCGCTCACGACGGTGCTGCTCGATCCGGCGCTGGTCGCGAGCCTG
GCCACCGGTGTGCCGGAGGCCGAGGCCTCGCCGATCCGGTTCTCCCTGTTCCAGCCCGTCGACGACTCGGCCCGACAGCT
CTGGCAACAGACCGTCCACTACGTCAAGGAGTGTGTGCTCGCCGACGAGGCGCTCGCCACGCCGCTGGTGCTCGGCCATG
CCGCCCGGCTCCTCGCCGCGGTGACGCTCGCGGCCTTCCCGAGCGCCTCGACGGTCGCGTCCACCGCACATGACCGCGAT
GCCAAACCCGTTCTCCTGCAACGGGCGATCGGCTTCATCGAGGAGAACCTCGCCAACGACATCGCCCTCGCCGACATCGC
CGCGGCCGTCCACGTCTCGCCGAGAGCGGTGCAGTACATGTTCCGCCGCCATCTGGAGACGACCCCGCTGCAGTACCTCC
GCCGGTCGCGCCTGCACCACGCGCACATGGACCTGCTGGCCGCGGACCCGGCTCGCGAGACCGTCACACGGATCGCCGCC
CAGTGGGGGTTCGCCCACACCGGCAGGTTCGCGGTGATGTACCGCGAGGCCTACGGGCAGAGCCCGCACACCACCCTTCG
CGGGTGA

Upstream 100 bases:

>100_bases
GAATCTGTCCAGAACGGGCATGGGGGTCATCCCATCACACCCGCTCCCGGCGAAATTCGCGACGCCCATCCGGCTGGCGG
TGGGCAACGAATTGGTTAAA

Downstream 100 bases:

>100_bases
CGCGACGCCGTCACAGCTTGCCGATCACGTTCTCCGCGAACCACTCGAGGTTGCGGATCTTGTCGGCGAGCGGTTCGGTG
TCGGCCCCGGTGATGTAGGG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MSTNPGVQPQPRTASPAEVPPIARHLDSLGVLARTQVKIIDSDEAAAFLDDAYGSRLRLSRLANPTGGPVLTYSRHDAGS
FTIDDMAMAGGFTASPDPLHKVLAVWANRGRIAGRCAGIGGLARAGEVALMAQPDLPHDAEAEDVALTTVLLDPALVASL
ATGVPEAEASPIRFSLFQPVDDSARQLWQQTVHYVKECVLADEALATPLVLGHAARLLAAVTLAAFPSASTVASTAHDRD
AKPVLLQRAIGFIEENLANDIALADIAAAVHVSPRAVQYMFRRHLETTPLQYLRRSRLHHAHMDLLAADPARETVTRIAA
QWGFAHTGRFAVMYREAYGQSPHTTLRG

Sequences:

>Translated_348_residues
MSTNPGVQPQPRTASPAEVPPIARHLDSLGVLARTQVKIIDSDEAAAFLDDAYGSRLRLSRLANPTGGPVLTYSRHDAGS
FTIDDMAMAGGFTASPDPLHKVLAVWANRGRIAGRCAGIGGLARAGEVALMAQPDLPHDAEAEDVALTTVLLDPALVASL
ATGVPEAEASPIRFSLFQPVDDSARQLWQQTVHYVKECVLADEALATPLVLGHAARLLAAVTLAAFPSASTVASTAHDRD
AKPVLLQRAIGFIEENLANDIALADIAAAVHVSPRAVQYMFRRHLETTPLQYLRRSRLHHAHMDLLAADPARETVTRIAA
QWGFAHTGRFAVMYREAYGQSPHTTLRG
>Mature_347_residues
STNPGVQPQPRTASPAEVPPIARHLDSLGVLARTQVKIIDSDEAAAFLDDAYGSRLRLSRLANPTGGPVLTYSRHDAGSF
TIDDMAMAGGFTASPDPLHKVLAVWANRGRIAGRCAGIGGLARAGEVALMAQPDLPHDAEAEDVALTTVLLDPALVASLA
TGVPEAEASPIRFSLFQPVDDSARQLWQQTVHYVKECVLADEALATPLVLGHAARLLAAVTLAAFPSASTVASTAHDRDA
KPVLLQRAIGFIEENLANDIALADIAAAVHVSPRAVQYMFRRHLETTPLQYLRRSRLHHAHMDLLAADPARETVTRIAAQ
WGFAHTGRFAVMYREAYGQSPHTTLRG

Specific function: Probably involved in the positive regulation of the thc operon for the degradation of the thiocarbamate herbicide EPTC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788778, Length=119, Percent_Identity=31.0924369747899, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37253; Mature: 37122

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNPGVQPQPRTASPAEVPPIARHLDSLGVLARTQVKIIDSDEAAAFLDDAYGSRLRLS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHCCCHHHHH
RLANPTGGPVLTYSRHDAGSFTIDDMAMAGGFTASPDPLHKVLAVWANRGRIAGRCAGIG
HHCCCCCCCEEEEECCCCCCEEHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCC
GLARAGEVALMAQPDLPHDAEAEDVALTTVLLDPALVASLATGVPEAEASPIRFSLFQPV
CHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCC
DDSARQLWQQTVHYVKECVLADEALATPLVLGHAARLLAAVTLAAFPSASTVASTAHDRD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCC
AKPVLLQRAIGFIEENLANDIALADIAAAVHVSPRAVQYMFRRHLETTPLQYLRRSRLHH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
AHMDLLAADPARETVTRIAAQWGFAHTGRFAVMYREAYGQSPHTTLRG
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCC
>Mature Secondary Structure 
STNPGVQPQPRTASPAEVPPIARHLDSLGVLARTQVKIIDSDEAAAFLDDAYGSRLRLS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHCCCHHHHH
RLANPTGGPVLTYSRHDAGSFTIDDMAMAGGFTASPDPLHKVLAVWANRGRIAGRCAGIG
HHCCCCCCCEEEEECCCCCCEEHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCC
GLARAGEVALMAQPDLPHDAEAEDVALTTVLLDPALVASLATGVPEAEASPIRFSLFQPV
CHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCC
DDSARQLWQQTVHYVKECVLADEALATPLVLGHAARLLAAVTLAAFPSASTVASTAHDRD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCC
AKPVLLQRAIGFIEENLANDIALADIAAAVHVSPRAVQYMFRRHLETTPLQYLRRSRLHH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
AHMDLLAADPARETVTRIAAQWGFAHTGRFAVMYREAYGQSPHTTLRG
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7836301 [H]