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The map label for this gene is aroB [H]

Identifier: 108801201

GI number: 108801201

Start: 4500026

End: 4500955

Strand: Reverse

Name: aroB [H]

Synonym: Mmcs_4237

Alternate gene names: 108801201

Gene position: 4500955-4500026 (Counterclockwise)

Preceding gene: 108801202

Following gene: 108801189

Centisome position: 78.89

GC content: 70.54

Gene sequence:

>930_bases
GTGGCGGCGGTCGACTGCGGGACCAACTCGATCCGGTTGCTGATCGCCGATGCCGCCGACGGCCGGCTGACCGATGTGCA
CCGGGAGATGCGCATCGTGCGGCTGGGCCAAGGTGTCGACGCCACAGGCGAATTCGCACCGGACGCATTGGCCCGCACCC
AGGGTGCGCTGGCCGCGTACGCGGAGTTGATGCGCGCCTACGAGGTGGCGAAGGTGCGGATGGTCGCGACGTCGGCGGCC
CGCGACGTCGCCAACCGCGATGCGTTCTTCCAGATGACCGCCGACGTGCTGGGTGAGGTGGTCGACGGGGCGGTCGCCGA
GGTCATCACGGGTACCGAGGAAGCCGAGTTGTCGTTCCGCGGCGCGGTGGCCGAACTCGACCCGGCGGACGGGCCGTTCG
TCGTCGTCGACCTCGGCGGCGGGTCGACGGAGGTCGTGGTGGGCCGGGACCGGGTGGACGCGAGCTTCTCGGCCGACATC
GGCTGTGTGCGTTTGACGGAGCGGTGCCTGCACTCGGATCCGCCGACGGCCGAGGAGGTGTCGGCCGCGCGGGAGTTCAT
CCGCGGCGCGCTCGACGAGGCGCTGCAGCAGGTGCCCGTGCAGGGGGCGCGGACCTGGGTCGGCGTGGCGGGGACCATGA
CGACGCTCGCGGCGCTGGCGCATCGGATGACGACGTACGACTCCGAGGCAATTCACCTGTCGCGGGTGGGTTTTCGCTCA
CTGCTGGAGGTGTGCGACGAGCTCATCGCGATGACGCGTCAGCAGCGGGCGGCGCTGGGTCCGATGCACGAGGGGCGCGT
CGACGTGATCGGCGGCGGCGCGATCATCGTCGAGGAACTGGCGCGTGAACTCGGCGAGCGGGCCGGGATCAACGAACTGG
TCGTCAGCGAACACGACATCCTCGACGGCATCGCGCTGTCGATCGCCTAG

Upstream 100 bases:

>100_bases
GGCGTGAACCCGTTCGGTGACGAGGCGCTGGCGATCCTGGCCGCCGAACCGGGTATGCAGGGAATTCTGGACGCGGACGT
GTGGAGGTTGCGTGGTTAGG

Downstream 100 bases:

>100_bases
CGCACCGCGACGATCGGCAGCGCCGCACCGGCGGTGGCCGAAAGCCGTTGGCGCGCCAGGGCCGGCCACGCCTGCACCGC
GCAGAACGGGGCGCACTGGT

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAAVDCGTNSIRLLIADAADGRLTDVHREMRIVRLGQGVDATGEFAPDALARTQGALAAYAELMRAYEVAKVRMVATSAA
RDVANRDAFFQMTADVLGEVVDGAVAEVITGTEEAELSFRGAVAELDPADGPFVVVDLGGGSTEVVVGRDRVDASFSADI
GCVRLTERCLHSDPPTAEEVSAAREFIRGALDEALQQVPVQGARTWVGVAGTMTTLAALAHRMTTYDSEAIHLSRVGFRS
LLEVCDELIAMTRQQRAALGPMHEGRVDVIGGGAIIVEELARELGERAGINELVVSEHDILDGIALSIA

Sequences:

>Translated_309_residues
MAAVDCGTNSIRLLIADAADGRLTDVHREMRIVRLGQGVDATGEFAPDALARTQGALAAYAELMRAYEVAKVRMVATSAA
RDVANRDAFFQMTADVLGEVVDGAVAEVITGTEEAELSFRGAVAELDPADGPFVVVDLGGGSTEVVVGRDRVDASFSADI
GCVRLTERCLHSDPPTAEEVSAAREFIRGALDEALQQVPVQGARTWVGVAGTMTTLAALAHRMTTYDSEAIHLSRVGFRS
LLEVCDELIAMTRQQRAALGPMHEGRVDVIGGGAIIVEELARELGERAGINELVVSEHDILDGIALSIA
>Mature_308_residues
AAVDCGTNSIRLLIADAADGRLTDVHREMRIVRLGQGVDATGEFAPDALARTQGALAAYAELMRAYEVAKVRMVATSAAR
DVANRDAFFQMTADVLGEVVDGAVAEVITGTEEAELSFRGAVAELDPADGPFVVVDLGGGSTEVVVGRDRVDASFSADIG
CVRLTERCLHSDPPTAEEVSAAREFIRGALDEALQQVPVQGARTWVGVAGTMTTLAALAHRMTTYDSEAIHLSRVGFRSL
LEVCDELIAMTRQQRAALGPMHEGRVDVIGGGAIIVEELARELGERAGINELVVSEHDILDGIALSIA

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=216, Percent_Identity=31.0185185185185, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788848, Length=215, Percent_Identity=29.7674418604651, Blast_Score=88, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 32669; Mature: 32538

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVDCGTNSIRLLIADAADGRLTDVHREMRIVRLGQGVDATGEFAPDALARTQGALAAY
CCEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
AELMRAYEVAKVRMVATSAARDVANRDAFFQMTADVLGEVVDGAVAEVITGTEEAELSFR
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
GAVAELDPADGPFVVVDLGGGSTEVVVGRDRVDASFSADIGCVRLTERCLHSDPPTAEEV
CCCEECCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
SAAREFIRGALDEALQQVPVQGARTWVGVAGTMTTLAALAHRMTTYDSEAIHLSRVGFRS
HHHHHHHHHHHHHHHHHCCCCCCHHHEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLEVCDELIAMTRQQRAALGPMHEGRVDVIGGGAIIVEELARELGERAGINELVVSEHDI
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHCCHHH
LDGIALSIA
HHHHHEECC
>Mature Secondary Structure 
AAVDCGTNSIRLLIADAADGRLTDVHREMRIVRLGQGVDATGEFAPDALARTQGALAAY
CEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
AELMRAYEVAKVRMVATSAARDVANRDAFFQMTADVLGEVVDGAVAEVITGTEEAELSFR
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
GAVAELDPADGPFVVVDLGGGSTEVVVGRDRVDASFSADIGCVRLTERCLHSDPPTAEEV
CCCEECCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
SAAREFIRGALDEALQQVPVQGARTWVGVAGTMTTLAALAHRMTTYDSEAIHLSRVGFRS
HHHHHHHHHHHHHHHHHCCCCCCHHHEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLEVCDELIAMTRQQRAALGPMHEGRVDVIGGGAIIVEELARELGERAGINELVVSEHDI
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHCCHHH
LDGIALSIA
HHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]