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The map label for this gene is yxlA [H]

Identifier: 108801149

GI number: 108801149

Start: 4448650

End: 4450080

Strand: Reverse

Name: yxlA [H]

Synonym: Mmcs_4185

Alternate gene names: 108801149

Gene position: 4450080-4448650 (Counterclockwise)

Preceding gene: 108801151

Following gene: 108801148

Centisome position: 78.0

GC content: 69.04

Gene sequence:

>1431_bases
ATGTCCGCTGTCGCCACCGGTGAACCGGCCCCCGAGGTCACCGAGCGCCTCGAATCCGACCTCACCGTCATCCCGGAGTC
CGGACGGACGACCGACGTACGCGGTCAGTTCTGGATCTGGGCGGGGGCCAACATCGCGCCGATCAACTGGGTCCTCGGCG
CCCTCGGCGTCACTATGGGCCTGGGTCTGTGGGAGACGATCGCCGTTCTCGCGGTCGGCAACCTGATCGGGATGTCGCTG
TTCGGCATCTTCGTCGTGATCGGCCAGCGCACCGGGGTCACGGGAATGGTGCTGTCCCGGGCCATCTTCGGCCGCCGCGG
CGCCTACGTGCCCGCCGCCGTCCAGGCGGTCGTGTGCATGGGGTGGTGCGCGGTGAACACCTGGATCGTGCTCGACCTGG
TGATGGCGCTGCTCGGGCGCATCGGCATCGCCGATCCCGACAGCACCGCACACGGTCCGCGGATCGTGGTGGGTGCCGTC
ATCATGGTCATCCAGGTGGTGATCGCCTGGTTCGGCTACCGGGTGATCGCGGCGTTCGAACGCTGGACCGTGCCGCCGAC
CGTGGCGATCCTGGTCGCGATGACGGCGGTCGCCTGGTTCGGCCTCGACGTCGAATGGGGTTACGCCGGTGATGCGGCAC
TGACCACCGGAGAGCACATCGCCGCCCTGTCGGCCGTGATGACCGCCATCGGAATCGGCTGGGGCATCACCTGGTTCGGC
TACGCCGGCGACTACTCGCGGTTCGTGTCCACCACCGTGCCCGCCCGCAAACTCTTCGTGGCCAGTGCGCTGGGCCAGTT
CATCCCGGTCCTCTGGCTGGGCGCCCTGGGTGCGACGCTGGCGACGCTCAGCTCGTCCGCGGATCCGGGCGAGATCATCG
TCGACGCCTACGGCGCGCTGGCCATCCCCGTCCTGCTGCTCGTCGTCCATGGACCGCTGGCCACCAACATCCTCAACATC
TACACGTGCACGGTGTCGACCCAGGCGCTCGACATCCACATCAACCGCCGCATCCTCAACCTGGTCATCGGCGCCGTCGC
CATGGTCGGGGTCGTGCTCTTCGTGCTCAACGGCGACTTCGCGCTGATGATCGACAGCTGGCTGGTCGGCATCGTCGGCT
GGGTGGCGCCGTGGGCCGCGGTGGTTCTGGTGCACTGGTTCGTGATCGCGCGCCGCGAGGTCGACCCCGAGGCGCTCCTG
GCGCCGCCCGGCGCGGGGCTGCTGCCGACGGTGCGGCCGACCGCCCTGGTGGCACTGGGTGTCGGCATCCTCTTCACCTG
GATGTTCATGTACGGCATGACACCGCTGCTGCAGGGGCCGGTCGCGAGCGCGCTGGGCGGCGTCGACCTGTCGTGGCTGG
CCGGCGGAATCGCCGCGGCGGGTACCTATCTTGCACTGGAGGCGATCCGCGGGCGGCAACTGCAGAAGTGA

Upstream 100 bases:

>100_bases
GTGAACGTGCGATGTAAAACTATCGGGGATTGTCACCACATCGCTCAAGGATGGACACCGCAACGGCGCGGCTGACCTCT
TTCGGAGAACAGGAACCGCC

Downstream 100 bases:

>100_bases
TGTCACCGGATGGCGCTAACGTCCGTCCCATGAGTCACCGACTTGTGCGCATCTATCGCGAGGGGCGAGCGGCGTACCCC
CACACCATCGACTGCCCCTA

Product: cytosine/purines, uracil, thiamine, allantoin permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSAVATGEPAPEVTERLESDLTVIPESGRTTDVRGQFWIWAGANIAPINWVLGALGVTMGLGLWETIAVLAVGNLIGMSL
FGIFVVIGQRTGVTGMVLSRAIFGRRGAYVPAAVQAVVCMGWCAVNTWIVLDLVMALLGRIGIADPDSTAHGPRIVVGAV
IMVIQVVIAWFGYRVIAAFERWTVPPTVAILVAMTAVAWFGLDVEWGYAGDAALTTGEHIAALSAVMTAIGIGWGITWFG
YAGDYSRFVSTTVPARKLFVASALGQFIPVLWLGALGATLATLSSSADPGEIIVDAYGALAIPVLLLVVHGPLATNILNI
YTCTVSTQALDIHINRRILNLVIGAVAMVGVVLFVLNGDFALMIDSWLVGIVGWVAPWAAVVLVHWFVIARREVDPEALL
APPGAGLLPTVRPTALVALGVGILFTWMFMYGMTPLLQGPVASALGGVDLSWLAGGIAAAGTYLALEAIRGRQLQK

Sequences:

>Translated_476_residues
MSAVATGEPAPEVTERLESDLTVIPESGRTTDVRGQFWIWAGANIAPINWVLGALGVTMGLGLWETIAVLAVGNLIGMSL
FGIFVVIGQRTGVTGMVLSRAIFGRRGAYVPAAVQAVVCMGWCAVNTWIVLDLVMALLGRIGIADPDSTAHGPRIVVGAV
IMVIQVVIAWFGYRVIAAFERWTVPPTVAILVAMTAVAWFGLDVEWGYAGDAALTTGEHIAALSAVMTAIGIGWGITWFG
YAGDYSRFVSTTVPARKLFVASALGQFIPVLWLGALGATLATLSSSADPGEIIVDAYGALAIPVLLLVVHGPLATNILNI
YTCTVSTQALDIHINRRILNLVIGAVAMVGVVLFVLNGDFALMIDSWLVGIVGWVAPWAAVVLVHWFVIARREVDPEALL
APPGAGLLPTVRPTALVALGVGILFTWMFMYGMTPLLQGPVASALGGVDLSWLAGGIAAAGTYLALEAIRGRQLQK
>Mature_475_residues
SAVATGEPAPEVTERLESDLTVIPESGRTTDVRGQFWIWAGANIAPINWVLGALGVTMGLGLWETIAVLAVGNLIGMSLF
GIFVVIGQRTGVTGMVLSRAIFGRRGAYVPAAVQAVVCMGWCAVNTWIVLDLVMALLGRIGIADPDSTAHGPRIVVGAVI
MVIQVVIAWFGYRVIAAFERWTVPPTVAILVAMTAVAWFGLDVEWGYAGDAALTTGEHIAALSAVMTAIGIGWGITWFGY
AGDYSRFVSTTVPARKLFVASALGQFIPVLWLGALGATLATLSSSADPGEIIVDAYGALAIPVLLLVVHGPLATNILNIY
TCTVSTQALDIHINRRILNLVIGAVAMVGVVLFVLNGDFALMIDSWLVGIVGWVAPWAAVVLVHWFVIARREVDPEALLA
PPGAGLLPTVRPTALVALGVGILFTWMFMYGMTPLLQGPVASALGGVDLSWLAGGIAAAGTYLALEAIRGRQLQK

Specific function: Unknown

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320897, Length=325, Percent_Identity=25.5384615384615, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320902, Length=389, Percent_Identity=24.1645244215938, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320903, Length=341, Percent_Identity=25.2199413489736, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 50059; Mature: 49928

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVATGEPAPEVTERLESDLTVIPESGRTTDVRGQFWIWAGANIAPINWVLGALGVTMG
CCCCCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
LGLWETIAVLAVGNLIGMSLFGIFVVIGQRTGVTGMVLSRAIFGRRGAYVPAAVQAVVCM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
GWCAVNTWIVLDLVMALLGRIGIADPDSTAHGPRIVVGAVIMVIQVVIAWFGYRVIAAFE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RWTVPPTVAILVAMTAVAWFGLDVEWGYAGDAALTTGEHIAALSAVMTAIGIGWGITWFG
HCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCC
YAGDYSRFVSTTVPARKLFVASALGQFIPVLWLGALGATLATLSSSADPGEIIVDAYGAL
CCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHH
AIPVLLLVVHGPLATNILNIYTCTVSTQALDIHINRRILNLVIGAVAMVGVVLFVLNGDF
HHHHHHHHHCCHHHHHHEEEEEEEEECEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCH
ALMIDSWLVGIVGWVAPWAAVVLVHWFVIARREVDPEALLAPPGAGLLPTVRPTALVALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCCCCCCCCCCHHHHHHHH
VGILFTWMFMYGMTPLLQGPVASALGGVDLSWLAGGIAAAGTYLALEAIRGRQLQK
HHHHHHHHHHHCCCHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SAVATGEPAPEVTERLESDLTVIPESGRTTDVRGQFWIWAGANIAPINWVLGALGVTMG
CCCCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH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HHHHHHHHHHHCCCHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]