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The map label for this gene is fbpC [H]

Identifier: 108801146

GI number: 108801146

Start: 4445760

End: 4446836

Strand: Reverse

Name: fbpC [H]

Synonym: Mmcs_4182

Alternate gene names: 108801146

Gene position: 4446836-4445760 (Counterclockwise)

Preceding gene: 108801147

Following gene: 108801145

Centisome position: 77.94

GC content: 69.36

Gene sequence:

>1077_bases
GTGGCGCAGCGATTCAGCGGGTGGAGTTGGACACGGGTACTGGGTGCGGTGCTGCTCACCGCACTGCTGCCGCTGTCGCC
GTCGATCGCGCCCAGCGCGACCGCGTACTCCCGCGACGGGCTGCCCATCGAGACGCTCGAGGTGCCGTCGGCGGCGATGG
GGCGCAACATCCGCGTCCAATTCCAGGGTGGCGGACCGCATTCGGTGTACCTGCTCGACGGGCTGCGCGCCCAGGAGGAC
GCCAACGGCTGGGACATCAACACCGCGGCGTTCGAGTGGTTCTACGAATCCGGAGTGTCGGTCGTGATGCCGGTCGGCGG
ACAGTCGAGCTTCTACGCCGACTGGTACCAGCCCGCCGCCAACAGCGCCGGTGTGGTGACCTACAAGTGGGAGACCTTCC
TGACCCAGGAACTGCCGGGCTGGCTGGCGGCCAACCGCGGTCAGGACCCGCGCGGCAATGCCGTTGTGGGGCTGTCGATG
TCGGGCGGTGCTGCGCTGAACCTGGCGACCTGGTACCCGACCCAGTTCATCTTCGCGAGTTCCCTGTCCGGCTATCTCAA
CCCGTCCGCCGGGCTCTGGCCCACGCTGATCGGCTTCGCGATGAAGGATGCCGGCGGCTTCAACCCGCAGAACATGTGGG
GACCCACCAGCGACGTCGCCTGGCGGCGCAACGACCCGACCGTCAACGTCGGCCGACTGGCCGCCAACGGCACCGCGCTG
TGGATCTACTGCGGTGGCGGGGTGGCTTCGGATCTGGACACCGGCAGCGACTTCGGCGGCAACTTCAGCGCGGGATACCT
GGAGAACATCACGGTCTCGACGAACAAGGAGTTCCAGCAGAAGTATCTGGCCGCCGGCGGGCACAACGCGGTGTTCAACT
TCCCCCCGAAGGGCACCCACAGTTGGGGATACTGGGGTTCGCAGCTGCAGGCGATGAAGCCGGATCTGCTGCGGGTGCTC
GGGGTGGGGGTCGCTCCGCCGCCACCCCCGCCCGCCGCACCCGTGCCTCCGGCGCTCCCGGCACCGGCCGTCCCACCGGC
GCCCGTCCCGCCGGCGCCCGCACTGCCCGGAGCCTGA

Upstream 100 bases:

>100_bases
AGGTCTGATAACAAGCGGGTCAAGGCCCGCGCTTCGCCGGCGGTGCCCTGACCGACCGCTGTTAGCGTCGCCGAGTTCCA
CGAGACGAGACGGAGACGCG

Downstream 100 bases:

>100_bases
CCGCCTAAGGGGGAAGCGATGGACGTACATCGGGGCTGGGGTGTCGTACCCGCAGCGGTGATCGGCTTGGCGGTGCTACC
CGGCTCCGCCGCCGCCACCC

Product: putative esterase

Products: NA

Alternate protein names: Antigen 85 complex C; 85C; Ag85C; Fibronectin-binding protein C; Mycolyl transferase 85C [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MAQRFSGWSWTRVLGAVLLTALLPLSPSIAPSATAYSRDGLPIETLEVPSAAMGRNIRVQFQGGGPHSVYLLDGLRAQED
ANGWDINTAAFEWFYESGVSVVMPVGGQSSFYADWYQPAANSAGVVTYKWETFLTQELPGWLAANRGQDPRGNAVVGLSM
SGGAALNLATWYPTQFIFASSLSGYLNPSAGLWPTLIGFAMKDAGGFNPQNMWGPTSDVAWRRNDPTVNVGRLAANGTAL
WIYCGGGVASDLDTGSDFGGNFSAGYLENITVSTNKEFQQKYLAAGGHNAVFNFPPKGTHSWGYWGSQLQAMKPDLLRVL
GVGVAPPPPPPAAPVPPALPAPAVPPAPVPPAPALPGA

Sequences:

>Translated_358_residues
MAQRFSGWSWTRVLGAVLLTALLPLSPSIAPSATAYSRDGLPIETLEVPSAAMGRNIRVQFQGGGPHSVYLLDGLRAQED
ANGWDINTAAFEWFYESGVSVVMPVGGQSSFYADWYQPAANSAGVVTYKWETFLTQELPGWLAANRGQDPRGNAVVGLSM
SGGAALNLATWYPTQFIFASSLSGYLNPSAGLWPTLIGFAMKDAGGFNPQNMWGPTSDVAWRRNDPTVNVGRLAANGTAL
WIYCGGGVASDLDTGSDFGGNFSAGYLENITVSTNKEFQQKYLAAGGHNAVFNFPPKGTHSWGYWGSQLQAMKPDLLRVL
GVGVAPPPPPPAAPVPPALPAPAVPPAPVPPAPALPGA
>Mature_357_residues
AQRFSGWSWTRVLGAVLLTALLPLSPSIAPSATAYSRDGLPIETLEVPSAAMGRNIRVQFQGGGPHSVYLLDGLRAQEDA
NGWDINTAAFEWFYESGVSVVMPVGGQSSFYADWYQPAANSAGVVTYKWETFLTQELPGWLAANRGQDPRGNAVVGLSMS
GGAALNLATWYPTQFIFASSLSGYLNPSAGLWPTLIGFAMKDAGGFNPQNMWGPTSDVAWRRNDPTVNVGRLAANGTALW
IYCGGGVASDLDTGSDFGGNFSAGYLENITVSTNKEFQQKYLAAGGHNAVFNFPPKGTHSWGYWGSQLQAMKPDLLRVLG
VGVAPPPPPPAAPVPPALPAPAVPPAPVPPAPALPGA

Specific function: Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintain

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial A85 antigen family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 37721; Mature: 37590

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRFSGWSWTRVLGAVLLTALLPLSPSIAPSATAYSRDGLPIETLEVPSAAMGRNIRVQ
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCEEEEE
FQGGGPHSVYLLDGLRAQEDANGWDINTAAFEWFYESGVSVVMPVGGQSSFYADWYQPAA
EECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCEEHHHHCCCC
NSAGVVTYKWETFLTQELPGWLAANRGQDPRGNAVVGLSMSGGAALNLATWYPTQFIFAS
CCCCEEEEEHHHHHHHHCCCCEECCCCCCCCCCEEEEEEECCCCEEEEEEECCHHHHHHH
SLSGYLNPSAGLWPTLIGFAMKDAGGFNPQNMWGPTSDVAWRRNDPTVNVGRLAANGTAL
HCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCEEEEEEEECCCEE
WIYCGGGVASDLDTGSDFGGNFSAGYLENITVSTNKEFQQKYLAAGGHNAVFNFPPKGTH
EEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHCCCCCCEEECCCCCCC
SWGYWGSQLQAMKPDLLRVLGVGVAPPPPPPAAPVPPALPAPAVPPAPVPPAPALPGA
CCCCCCCHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AQRFSGWSWTRVLGAVLLTALLPLSPSIAPSATAYSRDGLPIETLEVPSAAMGRNIRVQ
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCEEEEE
FQGGGPHSVYLLDGLRAQEDANGWDINTAAFEWFYESGVSVVMPVGGQSSFYADWYQPAA
EECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCEEHHHHCCCC
NSAGVVTYKWETFLTQELPGWLAANRGQDPRGNAVVGLSMSGGAALNLATWYPTQFIFAS
CCCCEEEEEHHHHHHHHCCCCEECCCCCCCCCCEEEEEEECCCCEEEEEEECCHHHHHHH
SLSGYLNPSAGLWPTLIGFAMKDAGGFNPQNMWGPTSDVAWRRNDPTVNVGRLAANGTAL
HCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCEEEEEEEECCCEE
WIYCGGGVASDLDTGSDFGGNFSAGYLENITVSTNKEFQQKYLAAGGHNAVFNFPPKGTH
EEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHCCCCCCEEECCCCCCC
SWGYWGSQLQAMKPDLLRVLGVGVAPPPPPPAAPVPPALPAPAVPPAPVPPAPALPGA
CCCCCCCHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9284137 [H]