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The map label for this gene is mgtC [H]

Identifier: 108801075

GI number: 108801075

Start: 4377580

End: 4378296

Strand: Reverse

Name: mgtC [H]

Synonym: Mmcs_4111

Alternate gene names: 108801075

Gene position: 4378296-4377580 (Counterclockwise)

Preceding gene: 108801083

Following gene: 108801074

Centisome position: 76.74

GC content: 70.85

Gene sequence:

>717_bases
ATGTTGGCCGTCGACCTGCTCACCCGCGTCGGCCTTGCGACCGTGCTGGGCGTGGCGATCGGACTCGAGCGGCAGTGGCG
CTCGCGGATGGCCGGCCTGCAGACCATGGCGCTGGTGAGTACGGGCTCGGCGCTGTACCTCATCCTGGGTGCCTACAGCT
TCCCCGACGCCGACCCGACCCGGGTGGCCGCGCAGATCGTCTCGGGGATCGGTTTTCTCGGCGCCGGCGTGATCATGAAG
CAGGGCCTGTCGGTGACTGGGCTCAACACCGCGGCCACGCTGTGGTCGACGGCCGCGGTGGGGGCGCTGGCCGGCGCCTG
GCTGTGGCGGGAGGCGCTCGCCAGCGCGGTCATCGTGGTCGCGGTCAACCTGGCGCTGCACCCGCTGGCGGAGGCGATGG
ACCGCCGCAAGAACTGGGGCGGCAGGGAGCATCCGCCGGTGCACTACCTGCTGACGGTGGTCTGTCGCGAAGACCACGAC
ACCGATATCCGGGCGTTGCTCGTGCAGGCGGTCATCGACTCCCACCTGCAGTTGACGTCGTTGCGGTCGGTCGCCGCCGA
CGGGGGGAAGCTCCAGATCGCGGCCGGGGTGTCGGCGCTGGCGCGCGATGACGCGGTGCTCGAGAAGATCGTCGGAGTGC
TCGCGGTCGACGCGCGGGTGACCTCCGTGCGGTGGAACATTCCGGAAGAAGAGGCCAGCGGCCTCGCACGGCCGTAG

Upstream 100 bases:

>100_bases
GTAGAAGTGCCGCATCGCGCCGTCTCCGCTATCACTCAACCGTCACTTTTTTTGCGTGTCCGAGTGCCCGCACGGCGCTG
GACCGGCGACAATCACAGCC

Downstream 100 bases:

>100_bases
GCGTTGTACGGGCCGCAGTCGATATCAATTCGTAGCGTTTTCGCGCCGCGCGCCGAATAACAGGAAACGGCGCTGTGCAT
GTGGCGGCGTGGTTCACTTC

Product: MgtC/SapB transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MLAVDLLTRVGLATVLGVAIGLERQWRSRMAGLQTMALVSTGSALYLILGAYSFPDADPTRVAAQIVSGIGFLGAGVIMK
QGLSVTGLNTAATLWSTAAVGALAGAWLWREALASAVIVVAVNLALHPLAEAMDRRKNWGGREHPPVHYLLTVVCREDHD
TDIRALLVQAVIDSHLQLTSLRSVAADGGKLQIAAGVSALARDDAVLEKIVGVLAVDARVTSVRWNIPEEEASGLARP

Sequences:

>Translated_238_residues
MLAVDLLTRVGLATVLGVAIGLERQWRSRMAGLQTMALVSTGSALYLILGAYSFPDADPTRVAAQIVSGIGFLGAGVIMK
QGLSVTGLNTAATLWSTAAVGALAGAWLWREALASAVIVVAVNLALHPLAEAMDRRKNWGGREHPPVHYLLTVVCREDHD
TDIRALLVQAVIDSHLQLTSLRSVAADGGKLQIAAGVSALARDDAVLEKIVGVLAVDARVTSVRWNIPEEEASGLARP
>Mature_238_residues
MLAVDLLTRVGLATVLGVAIGLERQWRSRMAGLQTMALVSTGSALYLILGAYSFPDADPTRVAAQIVSGIGFLGAGVIMK
QGLSVTGLNTAATLWSTAAVGALAGAWLWREALASAVIVVAVNLALHPLAEAMDRRKNWGGREHPPVHYLLTVVCREDHD
TDIRALLVQAVIDSHLQLTSLRSVAADGGKLQIAAGVSALARDDAVLEKIVGVLAVDARVTSVRWNIPEEEASGLARP

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=146, Percent_Identity=36.986301369863, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 25040; Mature: 25040

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVDLLTRVGLATVLGVAIGLERQWRSRMAGLQTMALVSTGSALYLILGAYSFPDADPT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHH
RVAAQIVSGIGFLGAGVIMKQGLSVTGLNTAATLWSTAAVGALAGAWLWREALASAVIVV
HHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNLALHPLAEAMDRRKNWGGREHPPVHYLLTVVCREDHDTDIRALLVQAVIDSHLQLTS
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LRSVAADGGKLQIAAGVSALARDDAVLEKIVGVLAVDARVTSVRWNIPEEEASGLARP
HHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHCCCCCC
>Mature Secondary Structure
MLAVDLLTRVGLATVLGVAIGLERQWRSRMAGLQTMALVSTGSALYLILGAYSFPDADPT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHH
RVAAQIVSGIGFLGAGVIMKQGLSVTGLNTAATLWSTAAVGALAGAWLWREALASAVIVV
HHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNLALHPLAEAMDRRKNWGGREHPPVHYLLTVVCREDHDTDIRALLVQAVIDSHLQLTS
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LRSVAADGGKLQIAAGVSALARDDAVLEKIVGVLAVDARVTSVRWNIPEEEASGLARP
HHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA