Click here to switch to the map view.

The map label for this gene is atpB [H]

Identifier: 108800846

GI number: 108800846

Start: 4134947

End: 4135702

Strand: Reverse

Name: atpB [H]

Synonym: Mmcs_3882

Alternate gene names: 108800846

Gene position: 4135702-4134947 (Counterclockwise)

Preceding gene: 108800847

Following gene: 108800845

Centisome position: 72.49

GC content: 65.34

Gene sequence:

>756_bases
ATGACGCAGACGTTCCTCGCCGCCGAGAGCGGTATTCAGGTCGGCCACCACACGGAGGCCAACTGGTTCGGGCTGACGGT
CAACACCGACACGATCCTGTCCACCGCGATCGCGGCCGCGATCGTGCTCGGGCTGGCGTTCTTCCTGCGCGCCAAGGTGA
CGTCGACCGGGGTGCCCAACGGCGTTCAGCTGTTCTGGGAAGCGCTGACGGTGCAGATGCGCAACCAGATCGAGAGCGCC
ATCGGGATGCGGGTGGCCGGTTTCGTGCTCCCGCTGGCCGTCACGCTGTTCGCGTTCATCCTGATCGCCAACTGGCTGTC
GGTGCTGCCCGTCCAGTACTCCGACGAGACCGGCATCCACGAGCTGCTCAAGCCGGCGGCCTCGGACATCAACTTCGTGC
TGGCGCTGGCGCTGTTCGTGTTCATCGCCTACCACGCCGCCGGGTTCTGGCGCCGTGGCCTGCTCGGCCACCCGAAGAAG
CTGCTGAAGGGCCACGTCGCGATCCTCGCCCCGATCAACCTGGTCGAGGAACTGGCCAAGCCGATCTCGCTGTCACTGCG
ACTCTTCGGCAACATCTTCGCCGGCGGCATCCTGGTCGCCCTGATCGCGCTGTTCCCGCCGTGGATCATGTGGGCGCCCA
ACGCGATCTGGAAGAGCTTCGACCTCTTCGTCGGCGCGATCCAGGCGTTCATCTTCGCGCTGCTGACCATCCTGTACTTC
AGCCAGTCGATGGAGCTCGACGACCACCACGACTGA

Upstream 100 bases:

>100_bases
CGCTGTTCCAGGTGATCCTGGTGGCGTCCACGACTTTGCCGGTGGTCAAGAAACTCAAAGCCCAGGCCGCTGACGGACTC
GAAGGAGAGACTCCACAGCA

Downstream 100 bases:

>100_bases
CCGGACATCTGACCAGCACGACCCGCTCGAATCCAACGCTCGACCCACGTCCTGGTAGGCGACTACCAGATATCAAGGAG
GATAAGGAATGGATCCCACA

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTQTFLAAESGIQVGHHTEANWFGLTVNTDTILSTAIAAAIVLGLAFFLRAKVTSTGVPNGVQLFWEALTVQMRNQIESA
IGMRVAGFVLPLAVTLFAFILIANWLSVLPVQYSDETGIHELLKPAASDINFVLALALFVFIAYHAAGFWRRGLLGHPKK
LLKGHVAILAPINLVEELAKPISLSLRLFGNIFAGGILVALIALFPPWIMWAPNAIWKSFDLFVGAIQAFIFALLTILYF
SQSMELDDHHD

Sequences:

>Translated_251_residues
MTQTFLAAESGIQVGHHTEANWFGLTVNTDTILSTAIAAAIVLGLAFFLRAKVTSTGVPNGVQLFWEALTVQMRNQIESA
IGMRVAGFVLPLAVTLFAFILIANWLSVLPVQYSDETGIHELLKPAASDINFVLALALFVFIAYHAAGFWRRGLLGHPKK
LLKGHVAILAPINLVEELAKPISLSLRLFGNIFAGGILVALIALFPPWIMWAPNAIWKSFDLFVGAIQAFIFALLTILYF
SQSMELDDHHD
>Mature_250_residues
TQTFLAAESGIQVGHHTEANWFGLTVNTDTILSTAIAAAIVLGLAFFLRAKVTSTGVPNGVQLFWEALTVQMRNQIESAI
GMRVAGFVLPLAVTLFAFILIANWLSVLPVQYSDETGIHELLKPAASDINFVLALALFVFIAYHAAGFWRRGLLGHPKKL
LKGHVAILAPINLVEELAKPISLSLRLFGNIFAGGILVALIALFPPWIMWAPNAIWKSFDLFVGAIQAFIFALLTILYFS
QSMELDDHHD

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=208, Percent_Identity=35.0961538461538, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 27469; Mature: 27337

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTFLAAESGIQVGHHTEANWFGLTVNTDTILSTAIAAAIVLGLAFFLRAKVTSTGVPN
CCCCHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
GVQLFWEALTVQMRNQIESAIGMRVAGFVLPLAVTLFAFILIANWLSVLPVQYSDETGIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
ELLKPAASDINFVLALALFVFIAYHAAGFWRRGLLGHPKKLLKGHVAILAPINLVEELAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHH
PISLSLRLFGNIFAGGILVALIALFPPWIMWAPNAIWKSFDLFVGAIQAFIFALLTILYF
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQSMELDDHHD
HHCCCCCCCCC
>Mature Secondary Structure 
TQTFLAAESGIQVGHHTEANWFGLTVNTDTILSTAIAAAIVLGLAFFLRAKVTSTGVPN
CCCHHHHHCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
GVQLFWEALTVQMRNQIESAIGMRVAGFVLPLAVTLFAFILIANWLSVLPVQYSDETGIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
ELLKPAASDINFVLALALFVFIAYHAAGFWRRGLLGHPKKLLKGHVAILAPINLVEELAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHH
PISLSLRLFGNIFAGGILVALIALFPPWIMWAPNAIWKSFDLFVGAIQAFIFALLTILYF
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQSMELDDHHD
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]