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The map label for this gene is atpA

Identifier: 108800842

GI number: 108800842

Start: 4131056

End: 4132702

Strand: Reverse

Name: atpA

Synonym: Mmcs_3878

Alternate gene names: 108800842

Gene position: 4132702-4131056 (Counterclockwise)

Preceding gene: 108800843

Following gene: 108800841

Centisome position: 72.43

GC content: 65.88

Gene sequence:

>1647_bases
ATGGCAGAGTTGACTATCTCGGCTGCTGACATCCAAGGGGCGATCGAGGACTACGTCGCCAACTTCGCCACCGACACCGA
GCGGGAAGAGATCGGCACCGTCATCGACGCCGGTGACGGTATCGCGCACGTCGAGGGCCTGCCCTCGGTGATGACGCAGG
AGCTGCTCGAGTTCCCCGGCGGTGTCCTGGGTGTCGCGCTCAACCTCGACGAGCACAGCATCGGTGCGGTCATCCTCGGT
GACTTCGAGAAGATCGAAGAGGGCCAGCAGGTCAAGCGCACCGGCGAGGTGCTGTCGGTGCCGGTGGGTGACGGTTACCT
CGGCCGCGTGGTCAACCCGCTCGGTCAGCCGATCGACGGCCGCGGAGAGATCGAGACCACCGATCGTCGTGCGCTCGAGC
TGCAGGCGCCCTCGGTGGTGCAGCGCCAGGGCGTGAGCGAGCCGCTGCAGACCGGGATCAAGGCGATCGACTCGCAGACC
CCGATCGGCCGCGGCCAGCGCCAGCTGATCATCGGTGACCGCAAGACCGGCAAGACCGCGGTCTGCGTCGACACGATCCT
CAACCAGCGGCAGAACTGGGAGACGGGCGACCCGAACCAGCAGGTGCGCTGCGTGTACGTCGCGATCGGCCAGAAGGGCA
CCACGATCGCCAGCGTGCGCCGCACGCTCGAAGAGGGCGGCGCGATGGACTACACCACCATCGTCGCGGCGCCCGCATCG
GATTCGGCCGGCTTCAAATGGCTTGCGCCCTACACCGGTTCGGCGATCGCCCAGCACTGGATGTACGACGGCAAGCACGT
CCTGATCGTGTTCGACGATCTGACCAAGCACGCCGAGGCCTACCGCGCGATCTCGCTGCTGCTGCGCCGCCCGCCGGGCC
GCGAAGCCTTCCCCGGCGACGTGTTCTACCTGCACTCGCGGTTGCTGGAACGCTGCGCGAAGCTGTCCGACGAACTCGGC
GGCGGCTCGATGACCGGATTGCCGCTGATCGAGACGAAGGCCAACGACATCTCGGCCTACATCCCGACCAACGTCATCTC
GATCACCGACGGGCAGTGCTTCCTGGAGACCGACCTGTTCAACCAGGGTGTGCGTCCCGCCATCAACGTCGGCGTCTCGG
TGTCGCGTGTGGGTGGCGCCGCGCAGATCAAGGCGATGAAAGAGGTGGCGGGCTCGCTGCGACTGGATCTGTCCCAGTAC
CGCGAGCTGGAGTCGTTCGCGGCGTTCGCCTCCGACCTGGATGCGACGTCGAAGGCGCAGCTGGACCGCGGCGCCCGGCT
GGTCGAGCTGCTCAAGCAGCCGCAGAACAGCCCGATGCCCGTCGAGGAGCAGGTCGTCGCGATCTTCCTCGGCACCAGGG
GTCACCTCGACACGGTGCCGGTCGAGGACGTGCAGCGTTTCGAGCAGGAGCTGCTCGAACACGTCCGTTCGTCCAAGGAG
GAGATCTTCACCGAGATCCGCGAGAGCAAGAAGCTCTCCGACGAACTCGAGAAGACGCTGACCGATGTGGTCAACGAGTT
CAAGAAGGGCTTCGAGACCACCTCCGGTGAGTCCGTGGTTCCGGACGAGAACGTCGAGGCCATGTCCGAGGACGACGTCG
AGAAGGAATCGGTGAAGGTCCGCAAGCCCGCCCCGAAGAAGAAGTAA

Upstream 100 bases:

>100_bases
CGACGGGTCACTGGCTTCGCGGCTGGCTTCGGCTGAAACCCAGCTGCCCGACTAACTCCGAACCCCACCAGACTCAACAC
AAAGGCAGGAAGACGAACCC

Downstream 100 bases:

>100_bases
GGCGCTCATAACCCATGGCTGCCACACTGCGCGAACTGCGCGGCCGCATCCGCTCCGCCGGGTCGATCAAGAAGATCACC
AAGGCCCAGGAGATGATCGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MAELTISAADIQGAIEDYVANFATDTEREEIGTVIDAGDGIAHVEGLPSVMTQELLEFPGGVLGVALNLDEHSIGAVILG
DFEKIEEGQQVKRTGEVLSVPVGDGYLGRVVNPLGQPIDGRGEIETTDRRALELQAPSVVQRQGVSEPLQTGIKAIDSQT
PIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWETGDPNQQVRCVYVAIGQKGTTIASVRRTLEEGGAMDYTTIVAAPAS
DSAGFKWLAPYTGSAIAQHWMYDGKHVLIVFDDLTKHAEAYRAISLLLRRPPGREAFPGDVFYLHSRLLERCAKLSDELG
GGSMTGLPLIETKANDISAYIPTNVISITDGQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQY
RELESFAAFASDLDATSKAQLDRGARLVELLKQPQNSPMPVEEQVVAIFLGTRGHLDTVPVEDVQRFEQELLEHVRSSKE
EIFTEIRESKKLSDELEKTLTDVVNEFKKGFETTSGESVVPDENVEAMSEDDVEKESVKVRKPAPKKK

Sequences:

>Translated_548_residues
MAELTISAADIQGAIEDYVANFATDTEREEIGTVIDAGDGIAHVEGLPSVMTQELLEFPGGVLGVALNLDEHSIGAVILG
DFEKIEEGQQVKRTGEVLSVPVGDGYLGRVVNPLGQPIDGRGEIETTDRRALELQAPSVVQRQGVSEPLQTGIKAIDSQT
PIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWETGDPNQQVRCVYVAIGQKGTTIASVRRTLEEGGAMDYTTIVAAPAS
DSAGFKWLAPYTGSAIAQHWMYDGKHVLIVFDDLTKHAEAYRAISLLLRRPPGREAFPGDVFYLHSRLLERCAKLSDELG
GGSMTGLPLIETKANDISAYIPTNVISITDGQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQY
RELESFAAFASDLDATSKAQLDRGARLVELLKQPQNSPMPVEEQVVAIFLGTRGHLDTVPVEDVQRFEQELLEHVRSSKE
EIFTEIRESKKLSDELEKTLTDVVNEFKKGFETTSGESVVPDENVEAMSEDDVEKESVKVRKPAPKKK
>Mature_547_residues
AELTISAADIQGAIEDYVANFATDTEREEIGTVIDAGDGIAHVEGLPSVMTQELLEFPGGVLGVALNLDEHSIGAVILGD
FEKIEEGQQVKRTGEVLSVPVGDGYLGRVVNPLGQPIDGRGEIETTDRRALELQAPSVVQRQGVSEPLQTGIKAIDSQTP
IGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWETGDPNQQVRCVYVAIGQKGTTIASVRRTLEEGGAMDYTTIVAAPASD
SAGFKWLAPYTGSAIAQHWMYDGKHVLIVFDDLTKHAEAYRAISLLLRRPPGREAFPGDVFYLHSRLLERCAKLSDELGG
GSMTGLPLIETKANDISAYIPTNVISITDGQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYR
ELESFAAFASDLDATSKAQLDRGARLVELLKQPQNSPMPVEEQVVAIFLGTRGHLDTVPVEDVQRFEQELLEHVRSSKEE
IFTEIRESKKLSDELEKTLTDVVNEFKKGFETTSGESVVPDENVEAMSEDDVEKESVKVRKPAPKKK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=53.3730158730159, Blast_Score=568, Evalue=1e-162,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=53.3730158730159, Blast_Score=568, Evalue=1e-162,
Organism=Homo sapiens, GI19913428, Length=293, Percent_Identity=29.6928327645051, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI19913426, Length=293, Percent_Identity=29.0102389078498, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI32189394, Length=484, Percent_Identity=24.5867768595041, Blast_Score=110, Evalue=4e-24,
Organism=Escherichia coli, GI1790172, Length=516, Percent_Identity=49.4186046511628, Blast_Score=520, Evalue=1e-148,
Organism=Escherichia coli, GI1788251, Length=322, Percent_Identity=27.3291925465839, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790170, Length=379, Percent_Identity=24.0105540897098, Blast_Score=102, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=506, Percent_Identity=55.1383399209486, Blast_Score=590, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI71988080, Length=506, Percent_Identity=55.1383399209486, Blast_Score=589, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI71988074, Length=506, Percent_Identity=51.1857707509881, Blast_Score=536, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI17510931, Length=355, Percent_Identity=27.6056338028169, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=291, Percent_Identity=29.553264604811, Blast_Score=119, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=474, Percent_Identity=23.2067510548523, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=60, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=503, Percent_Identity=54.0755467196819, Blast_Score=557, Evalue=1e-159,
Organism=Saccharomyces cerevisiae, GI6322581, Length=417, Percent_Identity=25.8992805755396, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6319603, Length=297, Percent_Identity=28.6195286195286, Blast_Score=120, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24658560, Length=508, Percent_Identity=53.740157480315, Blast_Score=577, Evalue=1e-165,
Organism=Drosophila melanogaster, GI281361666, Length=302, Percent_Identity=29.1390728476821, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24646341, Length=302, Percent_Identity=29.1390728476821, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI17136796, Length=302, Percent_Identity=29.1390728476821, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24638766, Length=446, Percent_Identity=26.457399103139, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28574560, Length=423, Percent_Identity=26.241134751773, Blast_Score=100, Evalue=4e-21,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_MYCSJ (A3Q3B3)

Other databases:

- EMBL:   CP000580
- RefSeq:   YP_001072131.1
- ProteinModelPortal:   A3Q3B3
- SMR:   A3Q3B3
- STRING:   A3Q3B3
- EnsemblBacteria:   EBMYCT00000050375
- GeneID:   4879574
- GenomeReviews:   CP000580_GR
- KEGG:   mjl:Mjls_3864
- eggNOG:   COG0056
- GeneTree:   EBGT00050000014996
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- PhylomeDB:   A3Q3B3
- ProtClustDB:   PRK09281
- BioCyc:   MSP164757:MJLS_3864-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 59640; Mature: 59509

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELTISAADIQGAIEDYVANFATDTEREEIGTVIDAGDGIAHVEGLPSVMTQELLEFPG
CCEEEEEHHHHHHHHHHHHHHHCCCCCHHHHCCEEECCCCCHHHCCCHHHHHHHHHHCCC
GVLGVALNLDEHSIGAVILGDFEKIEEGQQVKRTGEVLSVPVGDGYLGRVVNPLGQPIDG
CEEEEEEECCCCCCCEEEECCHHHHHCCHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCC
RGEIETTDRRALELQAPSVVQRQGVSEPLQTGIKAIDSQTPIGRGQRQLIIGDRKTGKTA
CCCEECCCCCEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCH
VCVDTILNQRQNWETGDPNQQVRCVYVAIGQKGTTIASVRRTLEEGGAMDYTTIVAAPAS
HHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEECCC
DSAGFKWLAPYTGSAIAQHWMYDGKHVLIVFDDLTKHAEAYRAISLLLRRPPGREAFPGD
CCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCH
VFYLHSRLLERCAKLSDELGGGSMTGLPLIETKANDISAYIPTNVISITDGQCFLETDLF
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCCCEEEEECCCEEEEEHHH
NQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYRELESFAAFASDLDATSKAQ
CCCCCCHHHCCEEHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHH
LDRGARLVELLKQPQNSPMPVEEQVVAIFLGTRGHLDTVPVEDVQRFEQELLEHVRSSKE
HHHHHHHHHHHHCCCCCCCCHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
EIFTEIRESKKLSDELEKTLTDVVNEFKKGFETTSGESVVPDENVEAMSEDDVEKESVKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEE
RKPAPKKK
CCCCCCCC
>Mature Secondary Structure 
AELTISAADIQGAIEDYVANFATDTEREEIGTVIDAGDGIAHVEGLPSVMTQELLEFPG
CEEEEEHHHHHHHHHHHHHHHCCCCCHHHHCCEEECCCCCHHHCCCHHHHHHHHHHCCC
GVLGVALNLDEHSIGAVILGDFEKIEEGQQVKRTGEVLSVPVGDGYLGRVVNPLGQPIDG
CEEEEEEECCCCCCCEEEECCHHHHHCCHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCC
RGEIETTDRRALELQAPSVVQRQGVSEPLQTGIKAIDSQTPIGRGQRQLIIGDRKTGKTA
CCCEECCCCCEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCH
VCVDTILNQRQNWETGDPNQQVRCVYVAIGQKGTTIASVRRTLEEGGAMDYTTIVAAPAS
HHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEECCC
DSAGFKWLAPYTGSAIAQHWMYDGKHVLIVFDDLTKHAEAYRAISLLLRRPPGREAFPGD
CCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCH
VFYLHSRLLERCAKLSDELGGGSMTGLPLIETKANDISAYIPTNVISITDGQCFLETDLF
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCCCEEEEECCCEEEEEHHH
NQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYRELESFAAFASDLDATSKAQ
CCCCCCHHHCCEEHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHH
LDRGARLVELLKQPQNSPMPVEEQVVAIFLGTRGHLDTVPVEDVQRFEQELLEHVRSSKE
HHHHHHHHHHHHCCCCCCCCHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
EIFTEIRESKKLSDELEKTLTDVVNEFKKGFETTSGESVVPDENVEAMSEDDVEKESVKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEE
RKPAPKKK
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA