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The map label for this gene is murA [H]

Identifier: 108800836

GI number: 108800836

Start: 4125797

End: 4127050

Strand: Reverse

Name: murA [H]

Synonym: Mmcs_3872

Alternate gene names: 108800836

Gene position: 4127050-4125797 (Counterclockwise)

Preceding gene: 108800838

Following gene: 108800833

Centisome position: 72.34

GC content: 68.18

Gene sequence:

>1254_bases
GTGAGCGAGCGATTCGTGGTGACCGGCGGCAACCGGTTATCGGGCGAAGTCGCGGTGGGCGGAGCGAAGAACAGCGTGCT
GAAACTGATGGCCGCATCGCTGTTGGCCGAGGGGACGAGCACGATCACGAACTGCCCCGACATCCTCGACGTCCCGCTGA
TGGCCGAGGTGCTCAGGGGCCTGGGTGCCACGGTGGAGCTCGACGGTGACGTCGTGCGCATCACCTCCCCGGACGAACCA
AAGTACGACGCCGACTTCGCCGCGGTGCGCCAGTTCCGGGCGTCGGTCTGCGTGCTCGGCCCGTTGGTCGGGCGGTGCAA
GCGGGCCCGGGTGGCGTTGCCCGGCGGCGATGCGATCGGATCGCGCCCACTGGACATGCACCAGGCCGGTCTGCGCCAGC
TCGGTGCGCGCTGCAACATCGAGCACGGCTGCGTGGTCGCCGAGGCCGACGAACTGCACGGCGCGGAGATCCAGCTGGAG
TTCCCGTCGGTCGGGGCCACCGAGAACATCCTGATGGCCGCGGTGCTGGCCAAGGGTGTGACGACGATCCACAACGCCGC
CAGGGAACCGGACGTCGTCGACCTGTGCGCGATGCTCAACCAGATGGGCGCCCAGGTCGTGGGCGCCGGATCGTCGACGT
TGACGATCACCGGCGTCGACCGGCTCTATCCGACCGAACACCGGGTGATCGGGGACCGGATCGTTGCCGCGACGTGGGGG
ATCGCCGCGGCGATGACCCAAGGGGACATCTCGGTGACCGGCGTCGACCCACAGCATCTGCAGTTGGTTCTGCACAAACT
GCACGACGCGGGGGCGACCGTCACCCAGGACGACAACGGGTTCCGGGTCGTGCAGTACGAACGGCCGAAGGCGGTCAACG
TCGCGACCCTGCCGTTCCCCGGATTCCCGACCGATCTGCAACCGATGGCCATCGGGCTCGCGTCGATCGCCGACGGCACG
TCGATGATCACGGAGAACGTCTTCGAGGCCAGATTCCGCTTCGTCGAGGAGATGATCCGGCTCGGCGCGGATGCCCGCAC
GGACGGACACCATGCGGTGGTGCGCGGAATCCCGCAGTTGTCGAGTGCCCCGGTGTGGTCGTCGGACATACGCGCCGGCG
CCGGCCTGGTGCTCGCTGGTCTGGTCGCCGACGGCGACACCGAGGTGCACGACGTGTTCCACATCGACCGCGGCTACCCG
CTCTTCGTGGAGAACCTGAAGAGTCTGGGCGCCGAGATCGAGCGCGTGGTGTAG

Upstream 100 bases:

>100_bases
TGGGTCAAACCGTACTAGGCGCCCGGCAGGTGACCTTTTCGGAAGGCACGGGGACTTTCGGAAACTGACACGGCCGGAGC
CGCTGTTTACACTGACCGGC

Downstream 100 bases:

>100_bases
TCGCCGACGGTCTGACGCCGCGGAAATCGCGGTTGTCACGCCTCTGACCAGGCGATTTTGGCTTCGGCGCAACCTGTGCG
TAAGCTAACGGACATACCGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSERFVVTGGNRLSGEVAVGGAKNSVLKLMAASLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVVRITSPDEP
KYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSRPLDMHQAGLRQLGARCNIEHGCVVAEADELHGAEIQLE
FPSVGATENILMAAVLAKGVTTIHNAAREPDVVDLCAMLNQMGAQVVGAGSSTLTITGVDRLYPTEHRVIGDRIVAATWG
IAAAMTQGDISVTGVDPQHLQLVLHKLHDAGATVTQDDNGFRVVQYERPKAVNVATLPFPGFPTDLQPMAIGLASIADGT
SMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGIPQLSSAPVWSSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYP
LFVENLKSLGAEIERVV

Sequences:

>Translated_417_residues
MSERFVVTGGNRLSGEVAVGGAKNSVLKLMAASLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVVRITSPDEP
KYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSRPLDMHQAGLRQLGARCNIEHGCVVAEADELHGAEIQLE
FPSVGATENILMAAVLAKGVTTIHNAAREPDVVDLCAMLNQMGAQVVGAGSSTLTITGVDRLYPTEHRVIGDRIVAATWG
IAAAMTQGDISVTGVDPQHLQLVLHKLHDAGATVTQDDNGFRVVQYERPKAVNVATLPFPGFPTDLQPMAIGLASIADGT
SMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGIPQLSSAPVWSSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYP
LFVENLKSLGAEIERVV
>Mature_416_residues
SERFVVTGGNRLSGEVAVGGAKNSVLKLMAASLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVVRITSPDEPK
YDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSRPLDMHQAGLRQLGARCNIEHGCVVAEADELHGAEIQLEF
PSVGATENILMAAVLAKGVTTIHNAAREPDVVDLCAMLNQMGAQVVGAGSSTLTITGVDRLYPTEHRVIGDRIVAATWGI
AAAMTQGDISVTGVDPQHLQLVLHKLHDAGATVTQDDNGFRVVQYERPKAVNVATLPFPGFPTDLQPMAIGLASIADGTS
MITENVFEARFRFVEEMIRLGADARTDGHHAVVRGIPQLSSAPVWSSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYPL
FVENLKSLGAEIERVV

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=416, Percent_Identity=44.7115384615385, Blast_Score=323, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44042; Mature: 43911

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERFVVTGGNRLSGEVAVGGAKNSVLKLMAASLLAEGTSTITNCPDILDVPLMAEVLRG
CCCCEEEECCCEECCEEEECCCHHHHHHHHHHHHHHCCCCHHCCCCCHHCHHHHHHHHHH
LGATVELDGDVVRITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIG
CCCEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCC
SRPLDMHQAGLRQLGARCNIEHGCVVAEADELHGAEIQLEFPSVGATENILMAAVLAKGV
CCCCHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
TTIHNAAREPDVVDLCAMLNQMGAQVVGAGSSTLTITGVDRLYPTEHRVIGDRIVAATWG
HHHHHHCCCCCHHHHHHHHHHHCCEEEECCCCEEEEEECHHHCCCCHHHHHCCHHHHHHH
IAAAMTQGDISVTGVDPQHLQLVLHKLHDAGATVTQDDNGFRVVQYERPKAVNVATLPFP
HHHHEECCCEEEECCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCEEEEEECCCC
GFPTDLQPMAIGLASIADGTSMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGIPQL
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCC
SSAPVWSSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLKSLGAEIERVV
CCCCCCCHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SERFVVTGGNRLSGEVAVGGAKNSVLKLMAASLLAEGTSTITNCPDILDVPLMAEVLRG
CCCEEEECCCEECCEEEECCCHHHHHHHHHHHHHHCCCCHHCCCCCHHCHHHHHHHHHH
LGATVELDGDVVRITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIG
CCCEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCC
SRPLDMHQAGLRQLGARCNIEHGCVVAEADELHGAEIQLEFPSVGATENILMAAVLAKGV
CCCCHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
TTIHNAAREPDVVDLCAMLNQMGAQVVGAGSSTLTITGVDRLYPTEHRVIGDRIVAATWG
HHHHHHCCCCCHHHHHHHHHHHCCEEEECCCCEEEEEECHHHCCCCHHHHHCCHHHHHHH
IAAAMTQGDISVTGVDPQHLQLVLHKLHDAGATVTQDDNGFRVVQYERPKAVNVATLPFP
HHHHEECCCEEEECCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCEEEEEECCCC
GFPTDLQPMAIGLASIADGTSMITENVFEARFRFVEEMIRLGADARTDGHHAVVRGIPQL
CCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCC
SSAPVWSSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLKSLGAEIERVV
CCCCCCCHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]