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The map label for this gene is yqeF [H]

Identifier: 108800761

GI number: 108800761

Start: 4049482

End: 4050633

Strand: Reverse

Name: yqeF [H]

Synonym: Mmcs_3796

Alternate gene names: 108800761

Gene position: 4050633-4049482 (Counterclockwise)

Preceding gene: 108800764

Following gene: 108800760

Centisome position: 71.0

GC content: 70.05

Gene sequence:

>1152_bases
ATGCCAGAAGCCGTCATCGTCTCTGCGCTGCGCACGCCCATCGGGACCGCCATGAAGGGCACGCTCCGCGATACCGACGC
CTACCGGTTGGCCGAGCACGTCGTCGCAGCCGCAGCCGAAGACCTGCCCACCGGCCAGATCGACGACGTCGTCCTCGGCG
AGGGGCTCTACGGCGGGGGAGTGATCGCCCGCCACGCCGCGATCACCGCCGGCCTGATCTCCGTGCCGGGCCTGTCGAAC
AACCGGCACTGCGCTGCGGGCCAGGCCGCGGTGCAGAGCGCCGCGGCGAGCATCCGCGCGGGCATGGACCAGCTGGTGAT
CGCAGGCGGGGTCAACTCGGCGTCCACCACACCGCGCTTCACCCGCCGTGCCAGCAGCGCGAAAGACGCCGCGATGCTCG
ACTGGTTCCCGCCCACGCACCCCGACCGTGCGGATGCCCCGAACATGGACATGTCGATCACCGTGGGCTGGAATGCCGCC
GTGCGCGCCGGGGTCAGCCGCGAGGAGATGGACCAGTGGGCTCTCGACTCCCACCGCAAGGCGATCCAGGCCATCGACGA
GGGCCGCTTCAAGGAGGAGATCGTCCCCATCGACACGCCCTACGGGCTCTTCGACACCGACGAACACCCCCGACGCGACA
CCAGCATCGAGAAGCTCGCCTCACTCAAGCCGCTGCACCCCGAGATCGAGGGTTTCTCGATCACGGCGGGCAACGCCTGC
GGCGCCAACGACGGAGCCGCGGTGCTGGCGCTGGCCAGTGACCGGCTCGGGCTACCCGCACTCGGCGCGGTGAAGGCCTG
GGCGTCGGTCGGCGTCGATCCGGCCTTCACCGGACTGGCGCCCGTCGAGGCCATCCCGAAAGCATTGAAGCGGGCGGGCA
TCTCGCTCTCCGACGTCGACCTGTTCGAGATCAACGAGGCGTTCGCGGCGATGTGCGTGGCCACCGTCAAGATGCTCGAC
ATCGATCCGGCCAAGGTCAACGTCAGCGGCAGCGGTTGTTCGCTGGGCCACCCGGTGGCCGCGACGGGCGCCAGGATGCT
GGTCACGTTGGTCCACGAGTTGCGCCGTCGCGGGGGAGGGATCGGTGTCGCGGCCATGTGCGCCGGCGGCGGTATGGGTT
CCGCGACCGTGATCGAGGTGCCGGCACCCTAG

Upstream 100 bases:

>100_bases
CTGAGCTACCGGCAATCTGCATGCGCTTCTCCTTCTTGCAACGATGACTCTCGTCCTGAGAGAATACTATTCTCATCCGA
CGCCGAAACGGAGTCAACTC

Downstream 100 bases:

>100_bases
GCTGGTGCACACATGGATGTAGACGAGCTGATCGCCGCCGCGCGCAACGGGTCGACCCGTGCCGCCGGCCGGCTGCTGAG
CCTGGTCGAGGGCACGCGCC

Product: acetyl-CoA C-acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MPEAVIVSALRTPIGTAMKGTLRDTDAYRLAEHVVAAAAEDLPTGQIDDVVLGEGLYGGGVIARHAAITAGLISVPGLSN
NRHCAAGQAAVQSAAASIRAGMDQLVIAGGVNSASTTPRFTRRASSAKDAAMLDWFPPTHPDRADAPNMDMSITVGWNAA
VRAGVSREEMDQWALDSHRKAIQAIDEGRFKEEIVPIDTPYGLFDTDEHPRRDTSIEKLASLKPLHPEIEGFSITAGNAC
GANDGAAVLALASDRLGLPALGAVKAWASVGVDPAFTGLAPVEAIPKALKRAGISLSDVDLFEINEAFAAMCVATVKMLD
IDPAKVNVSGSGCSLGHPVAATGARMLVTLVHELRRRGGGIGVAAMCAGGGMGSATVIEVPAP

Sequences:

>Translated_383_residues
MPEAVIVSALRTPIGTAMKGTLRDTDAYRLAEHVVAAAAEDLPTGQIDDVVLGEGLYGGGVIARHAAITAGLISVPGLSN
NRHCAAGQAAVQSAAASIRAGMDQLVIAGGVNSASTTPRFTRRASSAKDAAMLDWFPPTHPDRADAPNMDMSITVGWNAA
VRAGVSREEMDQWALDSHRKAIQAIDEGRFKEEIVPIDTPYGLFDTDEHPRRDTSIEKLASLKPLHPEIEGFSITAGNAC
GANDGAAVLALASDRLGLPALGAVKAWASVGVDPAFTGLAPVEAIPKALKRAGISLSDVDLFEINEAFAAMCVATVKMLD
IDPAKVNVSGSGCSLGHPVAATGARMLVTLVHELRRRGGGIGVAAMCAGGGMGSATVIEVPAP
>Mature_382_residues
PEAVIVSALRTPIGTAMKGTLRDTDAYRLAEHVVAAAAEDLPTGQIDDVVLGEGLYGGGVIARHAAITAGLISVPGLSNN
RHCAAGQAAVQSAAASIRAGMDQLVIAGGVNSASTTPRFTRRASSAKDAAMLDWFPPTHPDRADAPNMDMSITVGWNAAV
RAGVSREEMDQWALDSHRKAIQAIDEGRFKEEIVPIDTPYGLFDTDEHPRRDTSIEKLASLKPLHPEIEGFSITAGNACG
ANDGAAVLALASDRLGLPALGAVKAWASVGVDPAFTGLAPVEAIPKALKRAGISLSDVDLFEINEAFAAMCVATVKMLDI
DPAKVNVSGSGCSLGHPVAATGARMLVTLVHELRRRGGGIGVAAMCAGGGMGSATVIEVPAP

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI4501853, Length=403, Percent_Identity=39.2059553349876, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI148539872, Length=398, Percent_Identity=38.9447236180905, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI167614485, Length=397, Percent_Identity=36.272040302267, Blast_Score=208, Evalue=5e-54,
Organism=Homo sapiens, GI4557237, Length=393, Percent_Identity=34.0966921119593, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI4504327, Length=424, Percent_Identity=29.4811320754717, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI194353979, Length=385, Percent_Identity=29.8701298701299, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI87082165, Length=396, Percent_Identity=42.6767676767677, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1788554, Length=402, Percent_Identity=39.3034825870647, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI1787663, Length=404, Percent_Identity=38.1188118811881, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI48994986, Length=398, Percent_Identity=35.1758793969849, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI1788683, Length=427, Percent_Identity=32.5526932084309, Blast_Score=145, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI133906874, Length=394, Percent_Identity=35.2791878172589, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI25147385, Length=396, Percent_Identity=33.5858585858586, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17535921, Length=396, Percent_Identity=30.5555555555556, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17551802, Length=432, Percent_Identity=30.0925925925926, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17535917, Length=395, Percent_Identity=29.873417721519, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6322031, Length=390, Percent_Identity=34.8717948717949, Blast_Score=201, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6325229, Length=393, Percent_Identity=34.6055979643766, Blast_Score=195, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24655093, Length=395, Percent_Identity=37.7215189873418, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24640423, Length=403, Percent_Identity=33.7468982630273, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17648125, Length=401, Percent_Identity=33.9152119700748, Blast_Score=182, Evalue=5e-46,
Organism=Drosophila melanogaster, GI17137578, Length=427, Percent_Identity=30.4449648711944, Blast_Score=142, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 39448; Mature: 39317

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEAVIVSALRTPIGTAMKGTLRDTDAYRLAEHVVAAAAEDLPTGQIDDVVLGEGLYGGG
CCHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCC
VIARHAAITAGLISVPGLSNNRHCAAGQAAVQSAAASIRAGMDQLVIAGGVNSASTTPRF
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHH
TRRASSAKDAAMLDWFPPTHPDRADAPNMDMSITVGWNAAVRAGVSREEMDQWALDSHRK
HHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHH
AIQAIDEGRFKEEIVPIDTPYGLFDTDEHPRRDTSIEKLASLKPLHPEIEGFSITAGNAC
HHHHHHCCCCHHCEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCC
GANDGAAVLALASDRLGLPALGAVKAWASVGVDPAFTGLAPVEAIPKALKRAGISLSDVD
CCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCH
LFEINEAFAAMCVATVKMLDIDPAKVNVSGSGCSLGHPVAATGARMLVTLVHELRRRGGG
HHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
IGVAAMCAGGGMGSATVIEVPAP
CEEEEEECCCCCCCCEEEECCCC
>Mature Secondary Structure 
PEAVIVSALRTPIGTAMKGTLRDTDAYRLAEHVVAAAAEDLPTGQIDDVVLGEGLYGGG
CHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCC
VIARHAAITAGLISVPGLSNNRHCAAGQAAVQSAAASIRAGMDQLVIAGGVNSASTTPRF
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHH
TRRASSAKDAAMLDWFPPTHPDRADAPNMDMSITVGWNAAVRAGVSREEMDQWALDSHRK
HHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHH
AIQAIDEGRFKEEIVPIDTPYGLFDTDEHPRRDTSIEKLASLKPLHPEIEGFSITAGNAC
HHHHHHCCCCHHCEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCC
GANDGAAVLALASDRLGLPALGAVKAWASVGVDPAFTGLAPVEAIPKALKRAGISLSDVD
CCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCH
LFEINEAFAAMCVATVKMLDIDPAKVNVSGSGCSLGHPVAATGARMLVTLVHELRRRGGG
HHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
IGVAAMCAGGGMGSATVIEVPAP
CEEEEEECCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]