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The map label for this gene is mmgC [H]

Identifier: 108800705

GI number: 108800705

Start: 3992178

End: 3993326

Strand: Reverse

Name: mmgC [H]

Synonym: Mmcs_3740

Alternate gene names: 108800705

Gene position: 3993326-3992178 (Counterclockwise)

Preceding gene: 108800706

Following gene: 108800704

Centisome position: 69.99

GC content: 67.45

Gene sequence:

>1149_bases
GTGCGCCGAGACCTGTTCACCGACGACCACGACGCCTTCCGGCAGCTGGCCCGCGACTTCGTCGAGAAGGAGGTGGTGCC
GCAGTACCCGGAGTGGGAGAAGGCCGGCCGCATGCCGCGCGAGGTCTTCAAGCAGATGGGCGCACTCGGCATGCTCGGCA
TGGCGATCCCGGAGGAGTACGGGGGAGCGGGGATCGACGATTACCGCTACAACGTGGTGCTGCAGGAGGAGGCGGCCCGG
GCGCTGGTCACGCTGTCGACCGTGCGTACCCAGCTCGAGGTGATCCTGCCGTACTTCCTGCACTACGCGAACGACGAACA
GCGCAAGCGGTGGTTCCCCGGGCTGGCCGACGGCACCCTGCTGACCGCGATCGCGATGACCGAACCGGGCACCGGATCGG
ATCTGGCCGGGGTGCGGACCACCGCGGTGCGGGACGGCGACGACTACATCGTCAACGGCGCCAAGACCTTCATCACCGGC
GGCATCCAGGCCGACCTCGTGGTCGTGGTGGCCCGCACCTCGACCGATCCGGAGAACCGGCGCAGGGGCCTGTCGCTGAT
CGTCGTCGAGGACGGGATGCCCGGGTTCGAACGTGGCCGGGAGCTGGAGAAGATGGGCTGCAAGGTGCAGGACACGGCCG
AACTGTCGTTCACCGACGTCCGGGTGCCCGCGGCGAATTTGCTGGGGGAGGAGGGCGAGGCGTTCAGCTACCTCGGCCAC
AACCTCGCGCAGGAGCGGTTGACCGTGGCGGTGGGCTCGGTGGCGCAGGCCCGTTCGGCGCTGCACGCCACGATCGACTA
CGTCAAGAACCGCAAGGCGTTCGGCACCCCGGTGGCGTCGTTCCAGAACACGAAGTTCGAGTTGGCGGCCGTGTCCACCG
AGATCGAAGCGGCCCAGACGATGCTGGACCGGGCCGTGCTCGACCACGTCGACGGTGTGTTGTCGCGCGAGGACGCTGCT
CGCGTGAAGCTCTTCTGCACCGAGATGCAGGCCCGCGCTGTGGACCGCTGCCTGCAACTTTTCGGCGGCTACGGCTACAT
GATGGAGTACCCGATCGCGCGCCTGTACAACGACGCCCGGGTGGCCCGGATCTACGCGGGCACGAGTGAGGTCATGAAGG
TCATCATCGCCAAATCGCTCGGACTTTAA

Upstream 100 bases:

>100_bases
GTACGGACTGCAGACCATGTGCGAGGGCGGCGGCACGGCCAACGCGACCCTCGTCGAACTCATCGCCTAGACCACTTCCG
CCGACCAGGAGGACCCGAGC

Downstream 100 bases:

>100_bases
GCACTCTGCTGAGCGCCTGACCAGCAGTGTGACGCGCGTCCAAACCTAATTTCTCTGAGACCCTTGTCACATCGGCCAAA
CCTACCTACTGTGTGTTCAC

Product: acyl-CoA dehydrogenase-like protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MRRDLFTDDHDAFRQLARDFVEKEVVPQYPEWEKAGRMPREVFKQMGALGMLGMAIPEEYGGAGIDDYRYNVVLQEEAAR
ALVTLSTVRTQLEVILPYFLHYANDEQRKRWFPGLADGTLLTAIAMTEPGTGSDLAGVRTTAVRDGDDYIVNGAKTFITG
GIQADLVVVVARTSTDPENRRRGLSLIVVEDGMPGFERGRELEKMGCKVQDTAELSFTDVRVPAANLLGEEGEAFSYLGH
NLAQERLTVAVGSVAQARSALHATIDYVKNRKAFGTPVASFQNTKFELAAVSTEIEAAQTMLDRAVLDHVDGVLSREDAA
RVKLFCTEMQARAVDRCLQLFGGYGYMMEYPIARLYNDARVARIYAGTSEVMKVIIAKSLGL

Sequences:

>Translated_382_residues
MRRDLFTDDHDAFRQLARDFVEKEVVPQYPEWEKAGRMPREVFKQMGALGMLGMAIPEEYGGAGIDDYRYNVVLQEEAAR
ALVTLSTVRTQLEVILPYFLHYANDEQRKRWFPGLADGTLLTAIAMTEPGTGSDLAGVRTTAVRDGDDYIVNGAKTFITG
GIQADLVVVVARTSTDPENRRRGLSLIVVEDGMPGFERGRELEKMGCKVQDTAELSFTDVRVPAANLLGEEGEAFSYLGH
NLAQERLTVAVGSVAQARSALHATIDYVKNRKAFGTPVASFQNTKFELAAVSTEIEAAQTMLDRAVLDHVDGVLSREDAA
RVKLFCTEMQARAVDRCLQLFGGYGYMMEYPIARLYNDARVARIYAGTSEVMKVIIAKSLGL
>Mature_382_residues
MRRDLFTDDHDAFRQLARDFVEKEVVPQYPEWEKAGRMPREVFKQMGALGMLGMAIPEEYGGAGIDDYRYNVVLQEEAAR
ALVTLSTVRTQLEVILPYFLHYANDEQRKRWFPGLADGTLLTAIAMTEPGTGSDLAGVRTTAVRDGDDYIVNGAKTFITG
GIQADLVVVVARTSTDPENRRRGLSLIVVEDGMPGFERGRELEKMGCKVQDTAELSFTDVRVPAANLLGEEGEAFSYLGH
NLAQERLTVAVGSVAQARSALHATIDYVKNRKAFGTPVASFQNTKFELAAVSTEIEAAQTMLDRAVLDHVDGVLSREDAA
RVKLFCTEMQARAVDRCLQLFGGYGYMMEYPIARLYNDARVARIYAGTSEVMKVIIAKSLGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=378, Percent_Identity=42.8571428571429, Blast_Score=324, Evalue=8e-89,
Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=33.6, Blast_Score=228, Evalue=7e-60,
Organism=Homo sapiens, GI226958412, Length=378, Percent_Identity=32.010582010582, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI7656849, Length=380, Percent_Identity=33.1578947368421, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI226958414, Length=342, Percent_Identity=33.6257309941521, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI187960098, Length=374, Percent_Identity=31.0160427807487, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI4557231, Length=374, Percent_Identity=31.0160427807487, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=27.3936170212766, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI21361497, Length=351, Percent_Identity=29.3447293447293, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI76496475, Length=335, Percent_Identity=31.044776119403, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI4557235, Length=335, Percent_Identity=31.044776119403, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI4503943, Length=383, Percent_Identity=28.4595300261097, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI211971008, Length=389, Percent_Identity=27.2493573264781, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI48976061, Length=389, Percent_Identity=27.2493573264781, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI7669494, Length=357, Percent_Identity=29.4117647058824, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI38505218, Length=287, Percent_Identity=28.2229965156794, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI87081958, Length=362, Percent_Identity=28.4530386740331, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1786223, Length=376, Percent_Identity=26.5957446808511, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI87082384, Length=281, Percent_Identity=26.3345195729537, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081702, Length=356, Percent_Identity=24.7191011235955, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17570075, Length=376, Percent_Identity=36.1702127659575, Blast_Score=235, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17569725, Length=377, Percent_Identity=31.2997347480106, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17534899, Length=381, Percent_Identity=31.2335958005249, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=32.8042328042328, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17551932, Length=379, Percent_Identity=34.3007915567282, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17533517, Length=373, Percent_Identity=30.0268096514745, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17505929, Length=378, Percent_Identity=34.1269841269841, Blast_Score=198, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17506239, Length=375, Percent_Identity=29.3333333333333, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=362, Percent_Identity=28.4530386740331, Blast_Score=184, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI71985184, Length=351, Percent_Identity=28.7749287749288, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI71990804, Length=278, Percent_Identity=29.8561151079137, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17534353, Length=379, Percent_Identity=25.8575197889182, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71985192, Length=269, Percent_Identity=29.368029739777, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=29.004329004329, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71982178, Length=264, Percent_Identity=26.1363636363636, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17562446, Length=401, Percent_Identity=26.1845386533666, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI86563383, Length=269, Percent_Identity=27.8810408921933, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI86563381, Length=269, Percent_Identity=27.8810408921933, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=30.8510638297872, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24660351, Length=376, Percent_Identity=31.1170212765957, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI21355753, Length=377, Percent_Identity=32.0954907161804, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=29.5514511873351, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=29.0666666666667, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI281363737, Length=386, Percent_Identity=26.6839378238342, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI19920834, Length=381, Percent_Identity=27.2965879265092, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42226; Mature: 42226

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRDLFTDDHDAFRQLARDFVEKEVVPQYPEWEKAGRMPREVFKQMGALGMLGMAIPEEY
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHCCHHHHHHHCCHHH
GGAGIDDYRYNVVLQEEAARALVTLSTVRTQLEVILPYFLHYANDEQRKRWFPGLADGTL
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCE
LTAIAMTEPGTGSDLAGVRTTAVRDGDDYIVNGAKTFITGGIQADLVVVVARTSTDPENR
EEEEEECCCCCCCCCCCCEEEEEECCCCEEECCCHHEEECCCCEEEEEEEEECCCCHHHH
RRGLSLIVVEDGMPGFERGRELEKMGCKVQDTAELSFTDVRVPAANLLGEEGEAFSYLGH
HCCCEEEEEECCCCCHHHCCHHHHHCCCCCCCCCEEEEEEECCHHHHCCCCCCHHHHHHH
NLAQERLTVAVGSVAQARSALHATIDYVKNRKAFGTPVASFQNTKFELAAVSTEIEAAQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEEHHHHHHHHHH
MLDRAVLDHVDGVLSREDAARVKLFCTEMQARAVDRCLQLFGGYGYMMEYPIARLYNDAR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHCCHH
VARIYAGTSEVMKVIIAKSLGL
EEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRDLFTDDHDAFRQLARDFVEKEVVPQYPEWEKAGRMPREVFKQMGALGMLGMAIPEEY
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHCCHHHHHHHCCHHH
GGAGIDDYRYNVVLQEEAARALVTLSTVRTQLEVILPYFLHYANDEQRKRWFPGLADGTL
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCE
LTAIAMTEPGTGSDLAGVRTTAVRDGDDYIVNGAKTFITGGIQADLVVVVARTSTDPENR
EEEEEECCCCCCCCCCCCEEEEEECCCCEEECCCHHEEECCCCEEEEEEEEECCCCHHHH
RRGLSLIVVEDGMPGFERGRELEKMGCKVQDTAELSFTDVRVPAANLLGEEGEAFSYLGH
HCCCEEEEEECCCCCHHHCCHHHHHCCCCCCCCCEEEEEEECCHHHHCCCCCCHHHHHHH
NLAQERLTVAVGSVAQARSALHATIDYVKNRKAFGTPVASFQNTKFELAAVSTEIEAAQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEEHHHHHHHHHH
MLDRAVLDHVDGVLSREDAARVKLFCTEMQARAVDRCLQLFGGYGYMMEYPIARLYNDAR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHCCHH
VARIYAGTSEVMKVIIAKSLGL
EEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]