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The map label for this gene is yngE [H]

Identifier: 108800597

GI number: 108800597

Start: 3876642

End: 3878192

Strand: Reverse

Name: yngE [H]

Synonym: Mmcs_3631

Alternate gene names: 108800597

Gene position: 3878192-3876642 (Counterclockwise)

Preceding gene: 108800599

Following gene: 108800596

Centisome position: 67.97

GC content: 67.7

Gene sequence:

>1551_bases
ATGGCACCGCGGGCATCACATCGTGACGCGCACACAGCGCTCGTCGAGGAGTTACGCACCAAGCTCGCGGGTGCGGCGCT
CGGTGGGCCGGCCAAATCGCGCGAGCGCCACGTCAGCCGCGGCAAACTGCTGCCGCGCGACCGGGTCGACGGGCTGCTGG
ACGCGGGCAGCCCCTTTTTGGAGATCGCCCCGCTGGCCGCCGACGGTATGTACGACGACGAATGCCCGGGCGCGGGGATG
ATCGCCGGTATCGGCCGGATCTCCGGACGCGAATGCATGATCGTCGCCAACGACGCAACGGTCAAAGGCGGCACCTATTA
CCCGGTGACGGTCAAGAAGCACCTGCGCGCCCAGGAGATCGCCGGGCAGAACCGGTTACCCTGCGTGTACCTGGTCGACT
CCGGCGGTGCGTTCCTGCCGCGTCAGGACGAGGTGTTCCCGGACCGCGACCACTTCGGCCGGATCTTCTACAACCAGGCC
ACGCTGAGCGCGCAGGGCATCGCGCAGATCGCTGCGGTGCTCGGATCCTGCACCGCCGGTGGGGCTTACGTCCCGGCCAT
GAGCGACGAAGCGGTGATCGTGCGCAATCAGGGCACGATCTTCCTCGGCGGCCCTCCGCTGGTGAAGGCCGCCACCGGCG
AGGTCGTCTCCGCCGAGGACCTCGGCGGCGGTGACCTGCACTCCAAGACCTCCGGCGTCACCGACCACCTCGCCCACGAC
GACCGCGACGCGCTGCGGATCGTGCGCCGCATCGTCGGGACCCTCGGGCGGCCGCAGCCGCCACCCTGGGATGTGGCCCC
CGCGGTGGATGCGGTGGCCGATCAGTCCGAGCTCTACGACGTCGTCCCGGTCGACTCGCGGGTGCCCTACGACGTGCACG
AGGTCATCACCCGCATCGTCGACGGCGGCGAATTCGCGGAGTTCAAGGCCGAGTACGGCACCACGCTGGTCACCGGGTTC
GCGCGCATCCACGGCCATCCGGTCGGCATCGTCGCCAACAACGGCGTGCTGTTCGGCGAATCCGCGCAGAAGGGCGCCCA
TTTCATCGAGCTGTGCGACAAACGGGTGATCCCGCTGTTGTTCCTGCAGAACATCGCCGGGTTCATGGTCGGCCGCGACT
ACGAGGCCTCCGGGATCGCCAAACACGGCGCCAAGATGGTCACGGCCGTGGCGTGCGCACGGGTGCCCAAGCTGACCGTC
GTCATCGGAGGTTCCTACGGGGCGGGCAACTATTCGATGTGCGGTCGCGCGTATTCGCCGCGCTTCCTGTGGATGTGGCC
GAATGCACGGATCTCGGTGATGGGCGGTGAACAGGCCGCATCGGTGCTGGCCACGGTGCGAGGTGAGATGACGCCCGAGC
AGGAGCAGGAGTTCAAGGCGCCGATCCGCGAACAGTACGAACGTCAGGGCAACCCCTACTATTCGACCGCGCGGTTGTGG
GACGACGGTGTGATCGACCCGGCGGACACCAGAACCGTTGTGGGGTTGGCTCTTTCCATTGTCGGGCAGGCGCCACTCGA
GCCTGTCTCCTACGGCGTCTTCCGGATGTGA

Upstream 100 bases:

>100_bases
CCATGGACGGCCTCTTGCGGTGGGAGGTGGACATCGGGTGTTAATCGTGATTAACATACCACGAGTTAGTCGTCATTAAC
TCAAATGAACGGGTTCACGG

Downstream 100 bases:

>100_bases
TCCCGTGACATTCAACACCGTCCTGATTGCCAACCGCGGGGAGATCGCGGTCCGGGTGATCCGCACCCTGCGCGCGATGG
GTATCCGCTCGGTGGCGGTG

Product: propionyl-CoA carboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MAPRASHRDAHTALVEELRTKLAGAALGGPAKSRERHVSRGKLLPRDRVDGLLDAGSPFLEIAPLAADGMYDDECPGAGM
IAGIGRISGRECMIVANDATVKGGTYYPVTVKKHLRAQEIAGQNRLPCVYLVDSGGAFLPRQDEVFPDRDHFGRIFYNQA
TLSAQGIAQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGTIFLGGPPLVKAATGEVVSAEDLGGGDLHSKTSGVTDHLAHD
DRDALRIVRRIVGTLGRPQPPPWDVAPAVDAVADQSELYDVVPVDSRVPYDVHEVITRIVDGGEFAEFKAEYGTTLVTGF
ARIHGHPVGIVANNGVLFGESAQKGAHFIELCDKRVIPLLFLQNIAGFMVGRDYEASGIAKHGAKMVTAVACARVPKLTV
VIGGSYGAGNYSMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVRGEMTPEQEQEFKAPIREQYERQGNPYYSTARLW
DDGVIDPADTRTVVGLALSIVGQAPLEPVSYGVFRM

Sequences:

>Translated_516_residues
MAPRASHRDAHTALVEELRTKLAGAALGGPAKSRERHVSRGKLLPRDRVDGLLDAGSPFLEIAPLAADGMYDDECPGAGM
IAGIGRISGRECMIVANDATVKGGTYYPVTVKKHLRAQEIAGQNRLPCVYLVDSGGAFLPRQDEVFPDRDHFGRIFYNQA
TLSAQGIAQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGTIFLGGPPLVKAATGEVVSAEDLGGGDLHSKTSGVTDHLAHD
DRDALRIVRRIVGTLGRPQPPPWDVAPAVDAVADQSELYDVVPVDSRVPYDVHEVITRIVDGGEFAEFKAEYGTTLVTGF
ARIHGHPVGIVANNGVLFGESAQKGAHFIELCDKRVIPLLFLQNIAGFMVGRDYEASGIAKHGAKMVTAVACARVPKLTV
VIGGSYGAGNYSMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVRGEMTPEQEQEFKAPIREQYERQGNPYYSTARLW
DDGVIDPADTRTVVGLALSIVGQAPLEPVSYGVFRM
>Mature_515_residues
APRASHRDAHTALVEELRTKLAGAALGGPAKSRERHVSRGKLLPRDRVDGLLDAGSPFLEIAPLAADGMYDDECPGAGMI
AGIGRISGRECMIVANDATVKGGTYYPVTVKKHLRAQEIAGQNRLPCVYLVDSGGAFLPRQDEVFPDRDHFGRIFYNQAT
LSAQGIAQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGTIFLGGPPLVKAATGEVVSAEDLGGGDLHSKTSGVTDHLAHDD
RDALRIVRRIVGTLGRPQPPPWDVAPAVDAVADQSELYDVVPVDSRVPYDVHEVITRIVDGGEFAEFKAEYGTTLVTGFA
RIHGHPVGIVANNGVLFGESAQKGAHFIELCDKRVIPLLFLQNIAGFMVGRDYEASGIAKHGAKMVTAVACARVPKLTVV
IGGSYGAGNYSMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVRGEMTPEQEQEFKAPIREQYERQGNPYYSTARLWD
DGVIDPADTRTVVGLALSIVGQAPLEPVSYGVFRM

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI11545863, Length=513, Percent_Identity=64.9122807017544, Blast_Score=676, Evalue=0.0,
Organism=Homo sapiens, GI119943100, Length=510, Percent_Identity=32.9411764705882, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI295821216, Length=530, Percent_Identity=31.8867924528302, Blast_Score=222, Evalue=6e-58,
Organism=Homo sapiens, GI310133460, Length=124, Percent_Identity=63.7096774193548, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17552936, Length=517, Percent_Identity=61.5087040618955, Blast_Score=655, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147362, Length=529, Percent_Identity=34.0264650283554, Blast_Score=255, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI25147359, Length=529, Percent_Identity=34.0264650283554, Blast_Score=255, Evalue=5e-68,
Organism=Drosophila melanogaster, GI24586065, Length=533, Percent_Identity=61.9136960600375, Blast_Score=663, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: NA

Molecular weight: Translated: 55161; Mature: 55030

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPRASHRDAHTALVEELRTKLAGAALGGPAKSRERHVSRGKLLPRDRVDGLLDAGSPFL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCE
EIAPLAADGMYDDECPGAGMIAGIGRISGRECMIVANDATVKGGTYYPVTVKKHLRAQEI
EEEEEECCCCCCCCCCCCCCEEEHHCCCCCEEEEEECCCEECCCEEEEEEHHHHHHHHHH
AGQNRLPCVYLVDSGGAFLPRQDEVFPDRDHFGRIFYNQATLSAQGIAQIAAVLGSCTAG
CCCCCCCEEEEECCCCCCCCCCCCCCCCHHHCCEEEEECHHCCHHHHHHHHHHHHCCCCC
GAYVPAMSDEAVIVRNQGTIFLGGPPLVKAATGEVVSAEDLGGGDLHSKTSGVTDHLAHD
CEECCCCCCCEEEEECCCEEEECCCCEEEECCCCEEECCCCCCCCCCCCCCCCHHHHCCC
DRDALRIVRRIVGTLGRPQPPPWDVAPAVDAVADQSELYDVVPVDSRVPYDVHEVITRIV
CHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHCEEEEECCCCCCCCHHHHHHHHH
DGGEFAEFKAEYGTTLVTGFARIHGHPVGIVANNGVLFGESAQKGAHFIELCDKRVIPLL
CCCCHHHHHHHHCHHHHHHHHHHCCCEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHH
FLQNIAGFMVGRDYEASGIAKHGAKMVTAVACARVPKLTVVIGGSYGAGNYSMCGRAYSP
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHCCCCCCC
RFLWMWPNARISVMGGEQAASVLATVRGEMTPEQEQEFKAPIREQYERQGNPYYSTARLW
EEEEECCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHCCCCCEEEEEEC
DDGVIDPADTRTVVGLALSIVGQAPLEPVSYGVFRM
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
APRASHRDAHTALVEELRTKLAGAALGGPAKSRERHVSRGKLLPRDRVDGLLDAGSPFL
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCE
EIAPLAADGMYDDECPGAGMIAGIGRISGRECMIVANDATVKGGTYYPVTVKKHLRAQEI
EEEEEECCCCCCCCCCCCCCEEEHHCCCCCEEEEEECCCEECCCEEEEEEHHHHHHHHHH
AGQNRLPCVYLVDSGGAFLPRQDEVFPDRDHFGRIFYNQATLSAQGIAQIAAVLGSCTAG
CCCCCCCEEEEECCCCCCCCCCCCCCCCHHHCCEEEEECHHCCHHHHHHHHHHHHCCCCC
GAYVPAMSDEAVIVRNQGTIFLGGPPLVKAATGEVVSAEDLGGGDLHSKTSGVTDHLAHD
CEECCCCCCCEEEEECCCEEEECCCCEEEECCCCEEECCCCCCCCCCCCCCCCHHHHCCC
DRDALRIVRRIVGTLGRPQPPPWDVAPAVDAVADQSELYDVVPVDSRVPYDVHEVITRIV
CHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHCEEEEECCCCCCCCHHHHHHHHH
DGGEFAEFKAEYGTTLVTGFARIHGHPVGIVANNGVLFGESAQKGAHFIELCDKRVIPLL
CCCCHHHHHHHHCHHHHHHHHHHCCCEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHHH
FLQNIAGFMVGRDYEASGIAKHGAKMVTAVACARVPKLTVVIGGSYGAGNYSMCGRAYSP
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHCCCCCCC
RFLWMWPNARISVMGGEQAASVLATVRGEMTPEQEQEFKAPIREQYERQGNPYYSTARLW
EEEEECCCCEEEEECCHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHCCCCCEEEEEEC
DDGVIDPADTRTVVGLALSIVGQAPLEPVSYGVFRM
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9387222 [H]