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The map label for this gene is pcbC [H]

Identifier: 108800566

GI number: 108800566

Start: 3838926

End: 3839879

Strand: Reverse

Name: pcbC [H]

Synonym: Mmcs_3600

Alternate gene names: 108800566

Gene position: 3839879-3838926 (Counterclockwise)

Preceding gene: 108800567

Following gene: 108800565

Centisome position: 67.3

GC content: 71.7

Gene sequence:

>954_bases
ATGATCGCCACCATCGATCTGTCCCGCTGGTACGCCGGGGGAGCCGAGGCCGACGCCGTCGCCGCCGAGGTCGACGAAGG
ACTGCAGCAGGCGGGGTTCATCCTGGTCACCGGCCACGGGGTGGACCCGGTGCTGGCCGCCGACGTCCGCGCCGCCGCGC
GCGCCTTCTTCGCCCAGCCGCACGCCGTCAAGTCGCGCTACTCGGTGCCGGTCGGCGGCCACGGCTGGATCGGCCCCGGC
GCCGAGGCCAACGGGTACGCCGAGGGCACCGAGACCCCGCCGGATCTGAAGGAGAGCTTCAGCCTGGGCGCCGACACCCC
GACCGGCGACCCCGACATCGACCGGATCTGGTTCGCCGCCAACGTGTGGCCGGACGAGGTGCCCGGACTGCGTCCGCTGG
TGACCGCGTACACCGCGCAGATGCGCCGCGTCGCCGACGATCTGCTGGCCCTCTTCGCGCACGCACTCCGGTTGTCGCAC
AACCCGTTTGAGCGGCTCGCCGACCGGCCGACGTGGACGATGAACATCAACCACTACCCGCCGGTCTCCGTCGTCGGCGA
ACCCGAACCGGGACAGTTCCGCATCGGACCGCACACCGACTTCGGCACCGTCACCATCCTCGACCGGGAACCGGGGGCCG
GCGGGCTGCAGGTGTACTCCGAGGCCGACGGGTGGGCCGACGCCCCGTACCGCTCCGACGCGCTGACCGTCAACATCGGC
GACCTGCTCGAGTACTGGAGCGGGCGGCGCTGGCCGTCGGGCCGGCACCGGGTACTCCCGCCGCAGCCGGATGCACCCGA
GGAGGACCTCGTCTCGCTGATCTACTTCTACGAGGCCAATCACGACGCCGTCGTGACGCCGCTCGGCCCGCCGATCGGCA
GGGTGGCCGGGCTCGACCCGGTCACGTCGTCGGACTTCATCAAGGAGCGCCTCGACGCAATCACCGTCGGCTGA

Upstream 100 bases:

>100_bases
ACGGGGTCGAGGTCACCGTCCTCGACGACGACCGCTGCGTGTCGATGATGACCGAGTTCATCGACGCCGAACCCGACCTG
TGGAACGAGGACATCGGCCG

Downstream 100 bases:

>100_bases
CCTGTCACAATGGCCGCCATGCGCGTCTACCTGGGAGCCGACCACGCCGGCTACGAGTTGAAGCAGGTCATCATCGAGCA
CCTCCGCAGCACCGGCCACG

Product: 2OG-Fe(II) oxygenase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MIATIDLSRWYAGGAEADAVAAEVDEGLQQAGFILVTGHGVDPVLAADVRAAARAFFAQPHAVKSRYSVPVGGHGWIGPG
AEANGYAEGTETPPDLKESFSLGADTPTGDPDIDRIWFAANVWPDEVPGLRPLVTAYTAQMRRVADDLLALFAHALRLSH
NPFERLADRPTWTMNINHYPPVSVVGEPEPGQFRIGPHTDFGTVTILDREPGAGGLQVYSEADGWADAPYRSDALTVNIG
DLLEYWSGRRWPSGRHRVLPPQPDAPEEDLVSLIYFYEANHDAVVTPLGPPIGRVAGLDPVTSSDFIKERLDAITVG

Sequences:

>Translated_317_residues
MIATIDLSRWYAGGAEADAVAAEVDEGLQQAGFILVTGHGVDPVLAADVRAAARAFFAQPHAVKSRYSVPVGGHGWIGPG
AEANGYAEGTETPPDLKESFSLGADTPTGDPDIDRIWFAANVWPDEVPGLRPLVTAYTAQMRRVADDLLALFAHALRLSH
NPFERLADRPTWTMNINHYPPVSVVGEPEPGQFRIGPHTDFGTVTILDREPGAGGLQVYSEADGWADAPYRSDALTVNIG
DLLEYWSGRRWPSGRHRVLPPQPDAPEEDLVSLIYFYEANHDAVVTPLGPPIGRVAGLDPVTSSDFIKERLDAITVG
>Mature_317_residues
MIATIDLSRWYAGGAEADAVAAEVDEGLQQAGFILVTGHGVDPVLAADVRAAARAFFAQPHAVKSRYSVPVGGHGWIGPG
AEANGYAEGTETPPDLKESFSLGADTPTGDPDIDRIWFAANVWPDEVPGLRPLVTAYTAQMRRVADDLLALFAHALRLSH
NPFERLADRPTWTMNINHYPPVSVVGEPEPGQFRIGPHTDFGTVTILDREPGAGGLQVYSEADGWADAPYRSDALTVNIG
DLLEYWSGRRWPSGRHRVLPPQPDAPEEDLVSLIYFYEANHDAVVTPLGPPIGRVAGLDPVTSSDFIKERLDAITVG

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=305, Percent_Identity=22.2950819672131, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 34192; Mature: 34192

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIATIDLSRWYAGGAEADAVAAEVDEGLQQAGFILVTGHGVDPVLAADVRAAARAFFAQP
CEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHCCC
HAVKSRYSVPVGGHGWIGPGAEANGYAEGTETPPDLKESFSLGADTPTGDPDIDRIWFAA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEE
NVWPDEVPGLRPLVTAYTAQMRRVADDLLALFAHALRLSHNPFERLADRPTWTMNINHYP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCCC
PVSVVGEPEPGQFRIGPHTDFGTVTILDREPGAGGLQVYSEADGWADAPYRSDALTVNIG
CEEEECCCCCCCEEECCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCEEEEEHH
DLLEYWSGRRWPSGRHRVLPPQPDAPEEDLVSLIYFYEANHDAVVTPLGPPIGRVAGLDP
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHEEEEEEECCCCEEEECCCCCHHHHCCCCC
VTSSDFIKERLDAITVG
CCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MIATIDLSRWYAGGAEADAVAAEVDEGLQQAGFILVTGHGVDPVLAADVRAAARAFFAQP
CEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHCCC
HAVKSRYSVPVGGHGWIGPGAEANGYAEGTETPPDLKESFSLGADTPTGDPDIDRIWFAA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEE
NVWPDEVPGLRPLVTAYTAQMRRVADDLLALFAHALRLSHNPFERLADRPTWTMNINHYP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEECCCCC
PVSVVGEPEPGQFRIGPHTDFGTVTILDREPGAGGLQVYSEADGWADAPYRSDALTVNIG
CEEEECCCCCCCEEECCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCEEEEEHH
DLLEYWSGRRWPSGRHRVLPPQPDAPEEDLVSLIYFYEANHDAVVTPLGPPIGRVAGLDP
HHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHEEEEEEECCCCEEEECCCCCHHHHCCCCC
VTSSDFIKERLDAITVG
CCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1901702 [H]