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The map label for this gene is pcbC [H]

Identifier: 108800456

GI number: 108800456

Start: 3718280

End: 3719311

Strand: Reverse

Name: pcbC [H]

Synonym: Mmcs_3490

Alternate gene names: 108800456

Gene position: 3719311-3718280 (Counterclockwise)

Preceding gene: 108800457

Following gene: 108800455

Centisome position: 65.19

GC content: 69.77

Gene sequence:

>1032_bases
GTGTCCAGCGATCGTGAACGCCGCTCGCCTCACCGGCGTCGACGGCCGACAATGGCGCACGTGCTGCCCGTCCTCGACCT
CACCGACGCCGACACCGACCCGGCGGGTTTCCGCGCCCGGTTGCGGGAGGCCGCCCACGACGCCGGGTTCTTCTACCTCG
TCGGGCACGGTGTGCCGGTCGAGCGCTTCGAGCGGGTGCTGCGCCTGGCGCGTGACTTCTTCACCCAACCGCCGGAGCGA
AAGAACGAGATCAGCCAACTGCTCAGCCCGCAGTTCCGCGGATACTCCCGGCTCGGTGGGGAACTGACCAACGGCACCGT
GGACTGGCGCGAGCAGATCGACATCGGACCGGAGCGCGACGTCATCGAGGGCGCCGAAGGCTACTGGCGGCTGCAGGGGC
CGAACCTGTGGCCGGCGCAGCCGCCGGGATTCCGTGCCGCATTCGAAGAGTGGGGGGCCGCGCTGTCGGAGGTGGGTGTG
CGGCTGCTGCGGCACTGGGCGGTGTCGCTCGGTGCGGCCGAGGACACCTTCGACGCAGCCTTCGCCGACCGGCCCGCCAC
GTTGATGAAGGTGGTGCGCTATCCCGGCACGACCCAGACGGCGCAGGGTGTGGGCGCGCACAAGGACTCCGGGGTGTTGA
CGCTGCTGCTCGTCGAACCGGGATCGGTCGGGCTGCAGGTCGAGTCGGGCCCCGACGAGTGGATCGACGTACCGCCCCTT
CCCGGAGCCTTCATCGTCAACATCGGGGAACTGCTGGAGGTGGCGACGGGTGGGTACCTGCGTGCCACCCGCCACCGTGT
GCTCGCCCCGCCACCCGGCACGGACCGCATCTCGATCCCGTTTTTCCTCAACCCGGCCCTCGACGCGCTGATCCCCATCC
TGCCGTTGCCTCCGGAGCTGGCTGTGCGCTCGCGGGGGGTGGAAACCGACCCGGACAACCCGATCTTCAACACTTACGGG
GAGAACGCGTGGAAGTCGCGCACCCGGGCGCATCCCGACGTCGCCGAACTGCATCACGGCATCACCCGGTGA

Upstream 100 bases:

>100_bases
CCTTCGGCCCGGGTGGCGAGGCTGCGACGATCGCCACCGAGATGGTGGCCAACGCCGCGGAGGCGGTCCGCTAGGCACGG
CCTTCACCAACGCTGCAACG

Downstream 100 bases:

>100_bases
TTGCGTCGGCCTGATCGCAATGCTGTCGGCGCCTCGCGGTGCCGCCGTACGGTCACAACGTGTTCGATGTCCGCCGGCTC
GTGGTGTTGCGCGAAGTGGT

Product: 2OG-Fe(II) oxygenase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSSDRERRSPHRRRRPTMAHVLPVLDLTDADTDPAGFRARLREAAHDAGFFYLVGHGVPVERFERVLRLARDFFTQPPER
KNEISQLLSPQFRGYSRLGGELTNGTVDWREQIDIGPERDVIEGAEGYWRLQGPNLWPAQPPGFRAAFEEWGAALSEVGV
RLLRHWAVSLGAAEDTFDAAFADRPATLMKVVRYPGTTQTAQGVGAHKDSGVLTLLLVEPGSVGLQVESGPDEWIDVPPL
PGAFIVNIGELLEVATGGYLRATRHRVLAPPPGTDRISIPFFLNPALDALIPILPLPPELAVRSRGVETDPDNPIFNTYG
ENAWKSRTRAHPDVAELHHGITR

Sequences:

>Translated_343_residues
MSSDRERRSPHRRRRPTMAHVLPVLDLTDADTDPAGFRARLREAAHDAGFFYLVGHGVPVERFERVLRLARDFFTQPPER
KNEISQLLSPQFRGYSRLGGELTNGTVDWREQIDIGPERDVIEGAEGYWRLQGPNLWPAQPPGFRAAFEEWGAALSEVGV
RLLRHWAVSLGAAEDTFDAAFADRPATLMKVVRYPGTTQTAQGVGAHKDSGVLTLLLVEPGSVGLQVESGPDEWIDVPPL
PGAFIVNIGELLEVATGGYLRATRHRVLAPPPGTDRISIPFFLNPALDALIPILPLPPELAVRSRGVETDPDNPIFNTYG
ENAWKSRTRAHPDVAELHHGITR
>Mature_342_residues
SSDRERRSPHRRRRPTMAHVLPVLDLTDADTDPAGFRARLREAAHDAGFFYLVGHGVPVERFERVLRLARDFFTQPPERK
NEISQLLSPQFRGYSRLGGELTNGTVDWREQIDIGPERDVIEGAEGYWRLQGPNLWPAQPPGFRAAFEEWGAALSEVGVR
LLRHWAVSLGAAEDTFDAAFADRPATLMKVVRYPGTTQTAQGVGAHKDSGVLTLLLVEPGSVGLQVESGPDEWIDVPPLP
GAFIVNIGELLEVATGGYLRATRHRVLAPPPGTDRISIPFFLNPALDALIPILPLPPELAVRSRGVETDPDNPIFNTYGE
NAWKSRTRAHPDVAELHHGITR

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI85816264, Length=311, Percent_Identity=27.3311897106109, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 37950; Mature: 37819

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDRERRSPHRRRRPTMAHVLPVLDLTDADTDPAGFRARLREAAHDAGFFYLVGHGVPV
CCCCHHHCCCHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCH
ERFERVLRLARDFFTQPPERKNEISQLLSPQFRGYSRLGGELTNGTVDWREQIDIGPERD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHCCHHHCCCCCCCCEECHHHHCCCCCCCC
VIEGAEGYWRLQGPNLWPAQPPGFRAAFEEWGAALSEVGVRLLRHWAVSLGAAEDTFDAA
HHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
FADRPATLMKVVRYPGTTQTAQGVGAHKDSGVLTLLLVEPGSVGLQVESGPDEWIDVPPL
HCCCCHHHHHHHHCCCCCCHHCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
PGAFIVNIGELLEVATGGYLRATRHRVLAPPPGTDRISIPFFLNPALDALIPILPLPPEL
CCHHHHHHHHHHHHHCCCCEECCCCEEECCCCCCCEEEEEEEECHHHHHHHHCCCCCHHH
AVRSRGVETDPDNPIFNTYGENAWKSRTRAHPDVAELHHGITR
HHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHCCCCC
>Mature Secondary Structure 
SSDRERRSPHRRRRPTMAHVLPVLDLTDADTDPAGFRARLREAAHDAGFFYLVGHGVPV
CCCHHHCCCHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCH
ERFERVLRLARDFFTQPPERKNEISQLLSPQFRGYSRLGGELTNGTVDWREQIDIGPERD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHCCHHHCCCCCCCCEECHHHHCCCCCCCC
VIEGAEGYWRLQGPNLWPAQPPGFRAAFEEWGAALSEVGVRLLRHWAVSLGAAEDTFDAA
HHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
FADRPATLMKVVRYPGTTQTAQGVGAHKDSGVLTLLLVEPGSVGLQVESGPDEWIDVPPL
HCCCCHHHHHHHHCCCCCCHHCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
PGAFIVNIGELLEVATGGYLRATRHRVLAPPPGTDRISIPFFLNPALDALIPILPLPPEL
CCHHHHHHHHHHHHHCCCCEECCCCEEECCCCCCCEEEEEEEECHHHHHHHHCCCCCHHH
AVRSRGVETDPDNPIFNTYGENAWKSRTRAHPDVAELHHGITR
HHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3130293 [H]