Click here to switch to the map view.

The map label for this gene is era [H]

Identifier: 108800418

GI number: 108800418

Start: 3663223

End: 3664122

Strand: Reverse

Name: era [H]

Synonym: Mmcs_3452

Alternate gene names: 108800418

Gene position: 3664122-3663223 (Counterclockwise)

Preceding gene: 108800419

Following gene: 108800416

Centisome position: 64.22

GC content: 67.0

Gene sequence:

>900_bases
ATGAGCGAGTTCCGTTCGGGCTTCGTGTGTTTCGTCGGCAGGCCCAACACCGGCAAGTCGACCCTGACCAATGCGCTCGT
CGGCACCAAGGTGGCGATCACCTCCAACCGGCCGCAGACCACCCGGCACACCATCCGCGGCATCGTGCACCGCGACGAGT
TCCAGATCATCCTCGTCGACACGCCGGGTCTGCACCGGCCACGCACGCTGCTGGGGCAGCGGCTCAACGACCTGGTCAAG
ACCACCTACTCCGAGGTCGACGTGATCGGCCTGTGTATCCCCGCCGACGAGGCGATCGGGCCGGGAGACCGGTGGATCCA
CGAGCAGATCCGCGCCGTCGCGCCGCGGACCACGCTGGTCGTGATCGTCACCAAGATCGACAAGGTGCCCAGGGACCGGG
TCGCCGCGCAGTTGATGGCGGTCAGTGAACTGGTCGGGCCCGACGCCGAGATCGTGCCCGTCTCGGCGACCACCGGTGAA
CAGCTCGACGTGCTGACCGACGTACTGGCCGGCAAGCTGCCGCCCGGCCCGGCGTTCTACCCCGACGGCGAACTGACCGA
CGAACCCGAAGAGACGCTGATGGCCGAGTTGATCCGCGAGGCCGCGCTCGAAGGTGTGCGCGACGAGCTGCCGCACTCGC
TGGCGGTGGTCATCGACGAGGTGAGCCCGCGCGAGGACCGGGACGACCTCATCGACGTGCACGCCATCCTCTATGTCGAA
CGCGACAGCCAGAAGGGCATCGTGATCGGCAAGGGTGGCGCGCGGTTGCGCGAGGTGGGCACGGCCGCACGACTACAGAT
CGAGAAGCTGCTCGGCACGAAGGTCTACCTCGACCTGCGCGTGAAGATCGCCAAGAACTGGCAGCGCGACCCCAAACAGC
TTGGCCGACTGGGCTTTTAA

Upstream 100 bases:

>100_bases
GTCACCGACCGGTCCGGGAAGGTGCTCTCATGACCGCCGAGACTGCTCACAGATCACGTATCGCAGCGGAATCACGATCT
CACCGCAGGCTCGGCGATAG

Downstream 100 bases:

>100_bases
GCCGTCTCGCGCAGTTCCAGCGGGTCGCCGGACGGTCCGTCGTCCGTCGGGGCCTTCGCGGCCTGCGACATCTGCGGCGT
ATCCCACCACACCTTGGGCT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSEFRSGFVCFVGRPNTGKSTLTNALVGTKVAITSNRPQTTRHTIRGIVHRDEFQIILVDTPGLHRPRTLLGQRLNDLVK
TTYSEVDVIGLCIPADEAIGPGDRWIHEQIRAVAPRTTLVVIVTKIDKVPRDRVAAQLMAVSELVGPDAEIVPVSATTGE
QLDVLTDVLAGKLPPGPAFYPDGELTDEPEETLMAELIREAALEGVRDELPHSLAVVIDEVSPREDRDDLIDVHAILYVE
RDSQKGIVIGKGGARLREVGTAARLQIEKLLGTKVYLDLRVKIAKNWQRDPKQLGRLGF

Sequences:

>Translated_299_residues
MSEFRSGFVCFVGRPNTGKSTLTNALVGTKVAITSNRPQTTRHTIRGIVHRDEFQIILVDTPGLHRPRTLLGQRLNDLVK
TTYSEVDVIGLCIPADEAIGPGDRWIHEQIRAVAPRTTLVVIVTKIDKVPRDRVAAQLMAVSELVGPDAEIVPVSATTGE
QLDVLTDVLAGKLPPGPAFYPDGELTDEPEETLMAELIREAALEGVRDELPHSLAVVIDEVSPREDRDDLIDVHAILYVE
RDSQKGIVIGKGGARLREVGTAARLQIEKLLGTKVYLDLRVKIAKNWQRDPKQLGRLGF
>Mature_298_residues
SEFRSGFVCFVGRPNTGKSTLTNALVGTKVAITSNRPQTTRHTIRGIVHRDEFQIILVDTPGLHRPRTLLGQRLNDLVKT
TYSEVDVIGLCIPADEAIGPGDRWIHEQIRAVAPRTTLVVIVTKIDKVPRDRVAAQLMAVSELVGPDAEIVPVSATTGEQ
LDVLTDVLAGKLPPGPAFYPDGELTDEPEETLMAELIREAALEGVRDELPHSLAVVIDEVSPREDRDDLIDVHAILYVER
DSQKGIVIGKGGARLREVGTAARLQIEKLLGTKVYLDLRVKIAKNWQRDPKQLGRLGF

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=297, Percent_Identity=31.986531986532, Blast_Score=161, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 32862; Mature: 32731

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFRSGFVCFVGRPNTGKSTLTNALVGTKVAITSNRPQTTRHTIRGIVHRDEFQIILVD
CCCCCCCCEEEEECCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHEECCCEEEEEEE
TPGLHRPRTLLGQRLNDLVKTTYSEVDVIGLCIPADEAIGPGDRWIHEQIRAVAPRTTLV
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEE
VIVTKIDKVPRDRVAAQLMAVSELVGPDAEIVPVSATTGEQLDVLTDVLAGKLPPGPAFY
EEEEHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCC
PDGELTDEPEETLMAELIREAALEGVRDELPHSLAVVIDEVSPREDRDDLIDVHAILYVE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHEEEEEEEEEE
RDSQKGIVIGKGGARLREVGTAARLQIEKLLGTKVYLDLRVKIAKNWQRDPKQLGRLGF
ECCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEEHHCCCCCHHHHCCCCC
>Mature Secondary Structure 
SEFRSGFVCFVGRPNTGKSTLTNALVGTKVAITSNRPQTTRHTIRGIVHRDEFQIILVD
CCCCCCCEEEEECCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHEECCCEEEEEEE
TPGLHRPRTLLGQRLNDLVKTTYSEVDVIGLCIPADEAIGPGDRWIHEQIRAVAPRTTLV
CCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEE
VIVTKIDKVPRDRVAAQLMAVSELVGPDAEIVPVSATTGEQLDVLTDVLAGKLPPGPAFY
EEEEHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCC
PDGELTDEPEETLMAELIREAALEGVRDELPHSLAVVIDEVSPREDRDDLIDVHAILYVE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHEEEEEEEEEE
RDSQKGIVIGKGGARLREVGTAARLQIEKLLGTKVYLDLRVKIAKNWQRDPKQLGRLGF
ECCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEEHHCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA