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The map label for this gene is glyQS [H]

Identifier: 108800411

GI number: 108800411

Start: 3657276

End: 3658682

Strand: Reverse

Name: glyQS [H]

Synonym: Mmcs_3445

Alternate gene names: 108800411

Gene position: 3658682-3657276 (Counterclockwise)

Preceding gene: 108800414

Following gene: 108800409

Centisome position: 64.13

GC content: 66.03

Gene sequence:

>1407_bases
GTGGCTCCATCTTCTTCGATCATCGACACCGTTGCGAACCTGGCGAAACGCCGTGGACTGGTCTACCAATCCGGCGAGAT
CTACGGCGGCACGAAGTCGGCGTGGGACTACGGGCCGCTCGGGGTGGAGCTCAAGGAGAACATCAAGCGGCAGTGGTGGA
GGTCGGTGGTCACCGGCCGTGACGACGTCGTCGGCCTGGACAGCGCGATCATCCTGCCCCGGCAGGTGTGGGTGGCCTCC
GGCCACGTCGAGGTGTTCAACGACCCGCTCGTGGAATGCCTGAACTGCCACAAGCGCCATCGCCAGGACCACCTGCAGGA
GGCCTACTTCGAGAAGAAGGGGGCCAAGGACGGACTGGCCGGCCCGGACTCGGTGCCGATGGACGAGATCGTCTGCCCGG
ACTGCGGCACCAAGGGGCAGTGGACCGAACCGCGTGACTTCAACATGATGCTCAAGACCTACCTCGGCCCGATCGAGACC
GAGGAGGGTCTGCACTACCTGCGGCCCGAGACCGCGCAGGGCATCTTCGTCAACTTCGCCAACGTGGTCACCACCGCGCG
TAAGAAACCGCCGTTCGGCATCGGCCAGATCGGCAAGAGCTTCCGCAACGAGATCACCCCGGGCAACTTCATCTTCCGCA
CCCGCGAGTTCGAGCAGATGGAGATGGAGTTCTTCGTCGAGCCGTCGACCGCCAAGGAGTGGCACCAGTACTGGATCGAC
ACCCGGCTGCAGTGGTACGTCGACCTCGGCATCGACCGTGACAACCTGCGCCTCTACGAGCACCCGAAGGACAAGCTGTC
GCACTACTCGGACCGCACCGTCGACATCGAGTACAAGTTCGGCTTCGCCGGCAACCCGTGGGGCGAGCTCGAGGGCGTCG
CCAACCGCACCGATTTCGACCTGTCGACGCACGCGAAGCACTCCGGCGCCGACCTGTCGTTCTACGACCAGGCCACCGAG
ACCCGCTACACGCCATACGTGATCGAGCCGGCGGCGGGTCTGACCCGATCGCTGATGGCCTTCCTGGTCGACTCCTACAC
CGAGGACGAGGCGCCGAACGCCAAGGGCGGTGTCGACAAGCGCACGGTCTTGCGGCTCGACCCGCGGCTGGCGCCGGTCA
AGGCCGCGGTGCTGCCGCTGTCTCGCCACGCCGACCTGTCGCCCAAGGCGCGCGACCTCGCCGCGGAGTTGCGCAAGAAC
TGGAACGTCGAGTTCGACGATGCGGGGGCGATCGGCCGGCGCTACCGCCGCCAGGACGAGATCGGCACCCCGTACTGCAT
CACCGTCGACTTCGACTCGCTCACCGACCACGCCGTGACGATCCGCGAACGCGACACGATGACCCAGGACCGCGTCGCAC
TATCCGAGGTGTCCGACTACCTGGCGCTGCGGCTCAAGGGCTGCTGA

Upstream 100 bases:

>100_bases
TTTTCATTATGGCTGACACCATACATGCATCGATTCGCATGTCAACGGTGGCCGACGCCGTGGCGGGAGGGGCCGCCAGC
GCCCACTACGCTGTTGCACC

Downstream 100 bases:

>100_bases
GCCGCCCTTCGCGAGCAGACGCAAATGTGCCGCGACACGCGGTAATTCAGGGACATTTGTGTCTGCTCGCGGTGAGAAGT
CGACCCTAGAAGCGGCCGCC

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MAPSSSIIDTVANLAKRRGLVYQSGEIYGGTKSAWDYGPLGVELKENIKRQWWRSVVTGRDDVVGLDSAIILPRQVWVAS
GHVEVFNDPLVECLNCHKRHRQDHLQEAYFEKKGAKDGLAGPDSVPMDEIVCPDCGTKGQWTEPRDFNMMLKTYLGPIET
EEGLHYLRPETAQGIFVNFANVVTTARKKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWID
TRLQWYVDLGIDRDNLRLYEHPKDKLSHYSDRTVDIEYKFGFAGNPWGELEGVANRTDFDLSTHAKHSGADLSFYDQATE
TRYTPYVIEPAAGLTRSLMAFLVDSYTEDEAPNAKGGVDKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLAAELRKN
WNVEFDDAGAIGRRYRRQDEIGTPYCITVDFDSLTDHAVTIRERDTMTQDRVALSEVSDYLALRLKGC

Sequences:

>Translated_468_residues
MAPSSSIIDTVANLAKRRGLVYQSGEIYGGTKSAWDYGPLGVELKENIKRQWWRSVVTGRDDVVGLDSAIILPRQVWVAS
GHVEVFNDPLVECLNCHKRHRQDHLQEAYFEKKGAKDGLAGPDSVPMDEIVCPDCGTKGQWTEPRDFNMMLKTYLGPIET
EEGLHYLRPETAQGIFVNFANVVTTARKKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWID
TRLQWYVDLGIDRDNLRLYEHPKDKLSHYSDRTVDIEYKFGFAGNPWGELEGVANRTDFDLSTHAKHSGADLSFYDQATE
TRYTPYVIEPAAGLTRSLMAFLVDSYTEDEAPNAKGGVDKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLAAELRKN
WNVEFDDAGAIGRRYRRQDEIGTPYCITVDFDSLTDHAVTIRERDTMTQDRVALSEVSDYLALRLKGC
>Mature_467_residues
APSSSIIDTVANLAKRRGLVYQSGEIYGGTKSAWDYGPLGVELKENIKRQWWRSVVTGRDDVVGLDSAIILPRQVWVASG
HVEVFNDPLVECLNCHKRHRQDHLQEAYFEKKGAKDGLAGPDSVPMDEIVCPDCGTKGQWTEPRDFNMMLKTYLGPIETE
EGLHYLRPETAQGIFVNFANVVTTARKKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWIDT
RLQWYVDLGIDRDNLRLYEHPKDKLSHYSDRTVDIEYKFGFAGNPWGELEGVANRTDFDLSTHAKHSGADLSFYDQATET
RYTPYVIEPAAGLTRSLMAFLVDSYTEDEAPNAKGGVDKRTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLAAELRKNW
NVEFDDAGAIGRRYRRQDEIGTPYCITVDFDSLTDHAVTIRERDTMTQDRVALSEVSDYLALRLKGC

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=397, Percent_Identity=30.2267002518892, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32564541, Length=375, Percent_Identity=30.4, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17554996, Length=377, Percent_Identity=30.5039787798408, Blast_Score=155, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6325338, Length=451, Percent_Identity=27.0509977827051, Blast_Score=150, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6319597, Length=382, Percent_Identity=26.7015706806283, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24664462, Length=361, Percent_Identity=31.3019390581717, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI21357965, Length=375, Percent_Identity=30.9333333333333, Blast_Score=164, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022961
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 53152; Mature: 53021

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50862 AA_TRNA_LIGASE_II ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSSSIIDTVANLAKRRGLVYQSGEIYGGTKSAWDYGPLGVELKENIKRQWWRSVVTGR
CCCCHHHHHHHHHHHHHCCCEEECCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
DDVVGLDSAIILPRQVWVASGHVEVFNDPLVECLNCHKRHRQDHLQEAYFEKKGAKDGLA
CCEECCCCEEECCCEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GPDSVPMDEIVCPDCGTKGQWTEPRDFNMMLKTYLGPIETEEGLHYLRPETAQGIFVNFA
CCCCCCHHHEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHH
NVVTTARKKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWID
HHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHCCEEEEECCCCHHHHHHHHHC
TRLQWYVDLGIDRDNLRLYEHPKDKLSHYSDRTVDIEYKFGFAGNPWGELEGVANRTDFD
CEEEEEEEECCCCCCCEEEECCHHHHHCCCCCEEEEEEEECCCCCCCHHHCCCCCCCCCC
LSTHAKHSGADLSFYDQATETRYTPYVIEPAAGLTRSLMAFLVDSYTEDEAPNAKGGVDK
CHHCCCCCCCCCEEHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLAAELRKNWNVEFDDAGAIGRRYRRQDE
CEEEEECCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
IGTPYCITVDFDSLTDHAVTIRERDTMTQDRVALSEVSDYLALRLKGC
CCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHEEECCC
>Mature Secondary Structure 
APSSSIIDTVANLAKRRGLVYQSGEIYGGTKSAWDYGPLGVELKENIKRQWWRSVVTGR
CCCHHHHHHHHHHHHHCCCEEECCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
DDVVGLDSAIILPRQVWVASGHVEVFNDPLVECLNCHKRHRQDHLQEAYFEKKGAKDGLA
CCEECCCCEEECCCEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GPDSVPMDEIVCPDCGTKGQWTEPRDFNMMLKTYLGPIETEEGLHYLRPETAQGIFVNFA
CCCCCCHHHEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHH
NVVTTARKKPPFGIGQIGKSFRNEITPGNFIFRTREFEQMEMEFFVEPSTAKEWHQYWID
HHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHCCEEEEECCCCHHHHHHHHHC
TRLQWYVDLGIDRDNLRLYEHPKDKLSHYSDRTVDIEYKFGFAGNPWGELEGVANRTDFD
CEEEEEEEECCCCCCCEEEECCHHHHHCCCCCEEEEEEEECCCCCCCHHHCCCCCCCCCC
LSTHAKHSGADLSFYDQATETRYTPYVIEPAAGLTRSLMAFLVDSYTEDEAPNAKGGVDK
CHHCCCCCCCCCEEHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RTVLRLDPRLAPVKAAVLPLSRHADLSPKARDLAAELRKNWNVEFDDAGAIGRRYRRQDE
CEEEEECCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
IGTPYCITVDFDSLTDHAVTIRERDTMTQDRVALSEVSDYLALRLKGC
CCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA