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The map label for this gene is 108800374

Identifier: 108800374

GI number: 108800374

Start: 3617235

End: 3618641

Strand: Reverse

Name: 108800374

Synonym: Mmcs_3408

Alternate gene names: NA

Gene position: 3618641-3617235 (Counterclockwise)

Preceding gene: 108800379

Following gene: 108800370

Centisome position: 63.42

GC content: 68.51

Gene sequence:

>1407_bases
GTGCTCCCCGGCAGCCCTAACGTGTCCTTCGAGATGACTGAATTCATGCGTAACAGCGACGCGTTCACCTGGGCGATGGA
GACCGATCCCGGACTGCGTTCCACCGTGGTCACGGTGATCGTGCTCGAGCGATCCCCGGATTGGGATGAGCTGCGCGCGC
GTTTCGACCTGGTCTCGCGCAAGGTGCCGATGTTGAGGCAGCGGGTCGTCCCGTCGTCACCGCCGACGCCGCCGCGATGG
GAGTACGTCGCGGACTTCGACCTCGACTTCCACATGCGCAGAGTGACCGCGCCCGCCCCGGGCGGCTTCGACACCGTCTT
GGAGATGGCCAGGGTCGCGGCGATGGAGGATTTCGACCGTGCGCGTCCGCTCTGGGAGGCGACGCTGGTCGACGGGCTCG
ACGACGGCGGGGCTGCCGTGGTCCTGAAATTCCACCACGCCCTGACCGACGGGGTGGGAGGGGTCCAGATCGGGATGATC
CTGTTCGATCTGTCCGAGATCCCCGAGAAACACGGTCCGGTCGCGGAGGTCCCGGAGGTGACCCCGCCGCCGTGGCTGAG
CGGTTACCGCGAGACGGCGAAGTACGACGCCCGGCTGATCACCGACGCGGTGATCGGCACGGCGAGAAGCGCCCCGAGGC
TGATCCGCGACGGCATCCGTCGGCCGGTGTCGACGGTGTCGTCGGCGGCCCAGATCGCCGCGTCGGTCGTCCGGACCGTC
CGCCCGGTGAACCGGACGGGTTCGCCGATCATCAGGAAGCGCAGCCTGATTCGACGCCTCGGCGTGACAGAGGTTCCGTT
CCGGGAACTCCGGGACGCTGCCCACCGCTGCGACTGCGCGCTGAACGACGCATTCGTGGCCGGCGTGGCCGGCGGCCTCC
GCCGCTACCACGAACACCACGGCGCCGACGTCGGCGACCTGCACCTGACGATGCCGATCAGCCTGCGCGAGGAGGGCGAC
GAGCTGGGGGGTAACCGGATCACCCTGATGCGGTTCGACGTCCCCGTCGGGATCGCCGACCCCGCCGAACGGATCCGTCG
GATCCACGAGAGAACCAGCGCGGTTCGCCACGAGAAGTCGCTGCCCTACACCCAGTGGATCGCCGGCGCCCTGAACATGA
TGCCGCGGTGGTACATCGGCTCGATCCTGCGCAACGTCGATTTCCTGTGCAGCGACGTGCCGGGCGTACCGGTGCCGGTG
TTCCTCGGCGGCGCCCGGGTGGTGACGCAGTACGCCTTCGGCCCGACAATCGGCGCGGCGGTCAACGTCACTCTGCTGAC
CTACGTGGACATCTGCACGATCGGTATCGACGTCGACACCGGGGCGATCCCCGACTTCGACGTGTTCCGCCAGTGCCTCG
TCGACGGATTCGACGAGGTGCTGGCGCTCGCCTCGCCGAGCGCCTGA

Upstream 100 bases:

>100_bases
TCCGCTCCCTGTGGGCCGCGCAACAGGGTCTGAAGTCCCGAACCGATCGTCCGAACGAATCGACGTCCTGATCGGATAAG
AGACCAACGGCCCTGGTCCG

Downstream 100 bases:

>100_bases
GGCCGGTCAGCCGGGGAAGCGGACGGTGGTGCCCGGCATCAGCTGCACCACCCGCCCCCGGCATTCCACCACCACCCCGG
CGGCCTCGCGTGGGTCGACG

Product: diacylglycerol O-acyltransferase

Products: NA

Alternate protein names: Putative triacylglycerol synthase Rv2484c/MT2557 [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MLPGSPNVSFEMTEFMRNSDAFTWAMETDPGLRSTVVTVIVLERSPDWDELRARFDLVSRKVPMLRQRVVPSSPPTPPRW
EYVADFDLDFHMRRVTAPAPGGFDTVLEMARVAAMEDFDRARPLWEATLVDGLDDGGAAVVLKFHHALTDGVGGVQIGMI
LFDLSEIPEKHGPVAEVPEVTPPPWLSGYRETAKYDARLITDAVIGTARSAPRLIRDGIRRPVSTVSSAAQIAASVVRTV
RPVNRTGSPIIRKRSLIRRLGVTEVPFRELRDAAHRCDCALNDAFVAGVAGGLRRYHEHHGADVGDLHLTMPISLREEGD
ELGGNRITLMRFDVPVGIADPAERIRRIHERTSAVRHEKSLPYTQWIAGALNMMPRWYIGSILRNVDFLCSDVPGVPVPV
FLGGARVVTQYAFGPTIGAAVNVTLLTYVDICTIGIDVDTGAIPDFDVFRQCLVDGFDEVLALASPSA

Sequences:

>Translated_468_residues
MLPGSPNVSFEMTEFMRNSDAFTWAMETDPGLRSTVVTVIVLERSPDWDELRARFDLVSRKVPMLRQRVVPSSPPTPPRW
EYVADFDLDFHMRRVTAPAPGGFDTVLEMARVAAMEDFDRARPLWEATLVDGLDDGGAAVVLKFHHALTDGVGGVQIGMI
LFDLSEIPEKHGPVAEVPEVTPPPWLSGYRETAKYDARLITDAVIGTARSAPRLIRDGIRRPVSTVSSAAQIAASVVRTV
RPVNRTGSPIIRKRSLIRRLGVTEVPFRELRDAAHRCDCALNDAFVAGVAGGLRRYHEHHGADVGDLHLTMPISLREEGD
ELGGNRITLMRFDVPVGIADPAERIRRIHERTSAVRHEKSLPYTQWIAGALNMMPRWYIGSILRNVDFLCSDVPGVPVPV
FLGGARVVTQYAFGPTIGAAVNVTLLTYVDICTIGIDVDTGAIPDFDVFRQCLVDGFDEVLALASPSA
>Mature_468_residues
MLPGSPNVSFEMTEFMRNSDAFTWAMETDPGLRSTVVTVIVLERSPDWDELRARFDLVSRKVPMLRQRVVPSSPPTPPRW
EYVADFDLDFHMRRVTAPAPGGFDTVLEMARVAAMEDFDRARPLWEATLVDGLDDGGAAVVLKFHHALTDGVGGVQIGMI
LFDLSEIPEKHGPVAEVPEVTPPPWLSGYRETAKYDARLITDAVIGTARSAPRLIRDGIRRPVSTVSSAAQIAASVVRTV
RPVNRTGSPIIRKRSLIRRLGVTEVPFRELRDAAHRCDCALNDAFVAGVAGGLRRYHEHHGADVGDLHLTMPISLREEGD
ELGGNRITLMRFDVPVGIADPAERIRRIHERTSAVRHEKSLPYTQWIAGALNMMPRWYIGSILRNVDFLCSDVPGVPVPV
FLGGARVVTQYAFGPTIGAAVNVTLLTYVDICTIGIDVDTGAIPDFDVFRQCLVDGFDEVLALASPSA

Specific function: Upon expression in E.coli functions very weakly as a triacylglycerol synthase, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Has no wax synthase activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the long-chain O-acyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014292
- InterPro:   IPR004255 [H]

Pfam domain/function: PF03007 UPF0089 [H]

EC number: =2.3.1.20 [H]

Molecular weight: Translated: 51462; Mature: 51462

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPGSPNVSFEMTEFMRNSDAFTWAMETDPGLRSTVVTVIVLERSPDWDELRARFDLVSR
CCCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHEEEEEEEEECCCCHHHHHHHHHHHHH
KVPMLRQRVVPSSPPTPPRWEYVADFDLDFHMRRVTAPAPGGFDTVLEMARVAAMEDFDR
HHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEHEECCCCCCCHHHHHHHHHHHHHHHHHH
ARPLWEATLVDGLDDGGAAVVLKFHHALTDGVGGVQIGMILFDLSEIPEKHGPVAEVPEV
CCCHHHHHHHCCCCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCC
TPPPWLSGYRETAKYDARLITDAVIGTARSAPRLIRDGIRRPVSTVSSAAQIAASVVRTV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPVNRTGSPIIRKRSLIRRLGVTEVPFRELRDAAHRCDCALNDAFVAGVAGGLRRYHEHH
HCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GADVGDLHLTMPISLREEGDELGGNRITLMRFDVPVGIADPAERIRRIHERTSAVRHEKS
CCCCCCEEEEEEEEECCCHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
LPYTQWIAGALNMMPRWYIGSILRNVDFLCSDVPGVPVPVFLGGARVVTQYAFGPTIGAA
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHCCCCCHHH
VNVTLLTYVDICTIGIDVDTGAIPDFDVFRQCLVDGFDEVLALASPSA
HHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHCHHHHHHHCCCCC
>Mature Secondary Structure
MLPGSPNVSFEMTEFMRNSDAFTWAMETDPGLRSTVVTVIVLERSPDWDELRARFDLVSR
CCCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHEEEEEEEEECCCCHHHHHHHHHHHHH
KVPMLRQRVVPSSPPTPPRWEYVADFDLDFHMRRVTAPAPGGFDTVLEMARVAAMEDFDR
HHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEHEECCCCCCCHHHHHHHHHHHHHHHHHH
ARPLWEATLVDGLDDGGAAVVLKFHHALTDGVGGVQIGMILFDLSEIPEKHGPVAEVPEV
CCCHHHHHHHCCCCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHCCHHCCCCCCCCCC
TPPPWLSGYRETAKYDARLITDAVIGTARSAPRLIRDGIRRPVSTVSSAAQIAASVVRTV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPVNRTGSPIIRKRSLIRRLGVTEVPFRELRDAAHRCDCALNDAFVAGVAGGLRRYHEHH
HCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GADVGDLHLTMPISLREEGDELGGNRITLMRFDVPVGIADPAERIRRIHERTSAVRHEKS
CCCCCCEEEEEEEEECCCHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
LPYTQWIAGALNMMPRWYIGSILRNVDFLCSDVPGVPVPVFLGGARVVTQYAFGPTIGAA
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHCCCCCHHH
VNVTLLTYVDICTIGIDVDTGAIPDFDVFRQCLVDGFDEVLALASPSA
HHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]