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The map label for this gene is glnA [H]

Identifier: 108800294

GI number: 108800294

Start: 3527523

End: 3528863

Strand: Reverse

Name: glnA [H]

Synonym: Mmcs_3328

Alternate gene names: 108800294

Gene position: 3528863-3527523 (Counterclockwise)

Preceding gene: 108800295

Following gene: 108800293

Centisome position: 61.85

GC content: 67.19

Gene sequence:

>1341_bases
ATGGATCGCCAGAAGGAATTCGTGCTCCGCACGCTGGAGGAACGCGACATCCGCTTCGTCCGGTTGTGGTTCACGGACGT
CCTCGGTTACCTCAAGTCCGTGGCGATCGCGCCCGCCGAACTCGAGGGCGCCTTCGAGGAGGGCATCGGTTTCGACGGTT
CGTCGATCGAAGGCTTCGCGCGCGTCTCCGAAGCCGATATGGTCGCCCGCCCCGATCCGTCGACCTTCCAGGTGCTGCCA
TGGGCCGACGGCTCCGGTAAGCACCATTCGGCGCGGATGTTCTGCGACATCACGATGCCCGACGGTTCCCCGTCGTGGGC
GGATTCGCGCCATGTGCTGCGCCGTCAGCTCGGCAAGGCCAGCGACCTCGGGTTCTCCTGCTACGTGCACCCCGAGATCG
AGTTCTTCCTCCTCAAACCCGGCCCCAACGACGGCACCCCGCCCGTCCCGGCCGACAACGGCGGGTACTTCGACCAGGCC
GTGCACGATTCGGCCCCGAACTTCCGCAGGCATGCCATCGACGCGCTCGAGCAGATGGGCATCTCGGTGGAGTTCAGCCA
CCACGAGGGCGCTCCCGGCCAGCAGGAGATCGACCTGCGCTACGCCGACGCACTGTCGATGGCCGACAACGTGATGACGT
TCCGGTACGTCGTCAAGGAGGTCGCCCTCGGTGACGGTGTGCGGGCCTCGTTCATGCCCAAACCGTTCGCCGAGTACCCG
GGCTCGGCGATGCACACCCACATGAGCCTGTTCGAGGGCGACACCAACGCCTTCCACAGCCCCGACGACCCGCTGCAGCT
GTCCGACGTCGCCAAGTCGTTCATCGCCGGCATCCTCGAGCACGCCTGCGAGATCAGCGCCGTCACCAACCAATGGGTGA
ACTCCTACAAGCGACTGGTGCACGGCGGTGAGGCGCCGACCGCGGCGTCCTGGGGTGCGGCCAACCGCTCCGCGCTGGTG
CGGGTTCCGATGTACACACCGCGTAAGGCGTCGTCGCGCCGCATCGAGGTGCGCAGCCCCGATTCGGCGTGCAACCCGTA
CCTGACCTTCGCGGTGCTGCTGGCCGCCGGGCTGCGCGGTGTCGAGAAGGGCTACGTGCTCGCCCCGCAGGCGGAGGACA
ACGTCTGGAGCCTGACCCCCGAGGAGCGTCGCGCCATGGGATACCGGGAGCTGCCCACCAGCCTCGGCGTCGCACTCGGC
GAGATGGAGAACTCCGAACTGGTCGCCGAAGCGTTGGGGGAGCACGTGTTCGACTACTTCCTGCGCAACAAGCGCGCGGA
GTGGGAGACCTACCGCAGCCACGTCACGCCGTACGAGCTGCAGGCCTACCTGTCGCTGTAG

Upstream 100 bases:

>100_bases
GACGGCGTCGTGCCGCCGAACGGGTTGAGGTGCTGACCGAGATTCCACTCGGAGCAGCGCCGTAACACGGAATTAACAGC
CGGAACCTACGCTCGCGTTC

Downstream 100 bases:

>100_bases
TGCGGGCGCGGTAACGTCAGCGGCGTGGCCAGACCGTCGACCGAACGCTCCAAGCTGCCCAGCACCGGGCGCCTCGGGCT
GGTGGAGAAACAGGCCCCCG

Product: L-glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase 2 [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MDRQKEFVLRTLEERDIRFVRLWFTDVLGYLKSVAIAPAELEGAFEEGIGFDGSSIEGFARVSEADMVARPDPSTFQVLP
WADGSGKHHSARMFCDITMPDGSPSWADSRHVLRRQLGKASDLGFSCYVHPEIEFFLLKPGPNDGTPPVPADNGGYFDQA
VHDSAPNFRRHAIDALEQMGISVEFSHHEGAPGQQEIDLRYADALSMADNVMTFRYVVKEVALGDGVRASFMPKPFAEYP
GSAMHTHMSLFEGDTNAFHSPDDPLQLSDVAKSFIAGILEHACEISAVTNQWVNSYKRLVHGGEAPTAASWGAANRSALV
RVPMYTPRKASSRRIEVRSPDSACNPYLTFAVLLAAGLRGVEKGYVLAPQAEDNVWSLTPEERRAMGYRELPTSLGVALG
EMENSELVAEALGEHVFDYFLRNKRAEWETYRSHVTPYELQAYLSL

Sequences:

>Translated_446_residues
MDRQKEFVLRTLEERDIRFVRLWFTDVLGYLKSVAIAPAELEGAFEEGIGFDGSSIEGFARVSEADMVARPDPSTFQVLP
WADGSGKHHSARMFCDITMPDGSPSWADSRHVLRRQLGKASDLGFSCYVHPEIEFFLLKPGPNDGTPPVPADNGGYFDQA
VHDSAPNFRRHAIDALEQMGISVEFSHHEGAPGQQEIDLRYADALSMADNVMTFRYVVKEVALGDGVRASFMPKPFAEYP
GSAMHTHMSLFEGDTNAFHSPDDPLQLSDVAKSFIAGILEHACEISAVTNQWVNSYKRLVHGGEAPTAASWGAANRSALV
RVPMYTPRKASSRRIEVRSPDSACNPYLTFAVLLAAGLRGVEKGYVLAPQAEDNVWSLTPEERRAMGYRELPTSLGVALG
EMENSELVAEALGEHVFDYFLRNKRAEWETYRSHVTPYELQAYLSL
>Mature_446_residues
MDRQKEFVLRTLEERDIRFVRLWFTDVLGYLKSVAIAPAELEGAFEEGIGFDGSSIEGFARVSEADMVARPDPSTFQVLP
WADGSGKHHSARMFCDITMPDGSPSWADSRHVLRRQLGKASDLGFSCYVHPEIEFFLLKPGPNDGTPPVPADNGGYFDQA
VHDSAPNFRRHAIDALEQMGISVEFSHHEGAPGQQEIDLRYADALSMADNVMTFRYVVKEVALGDGVRASFMPKPFAEYP
GSAMHTHMSLFEGDTNAFHSPDDPLQLSDVAKSFIAGILEHACEISAVTNQWVNSYKRLVHGGEAPTAASWGAANRSALV
RVPMYTPRKASSRRIEVRSPDSACNPYLTFAVLLAAGLRGVEKGYVLAPQAEDNVWSLTPEERRAMGYRELPTSLGVALG
EMENSELVAEALGEHVFDYFLRNKRAEWETYRSHVTPYELQAYLSL

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=445, Percent_Identity=27.4157303370787, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1790301, Length=477, Percent_Identity=35.8490566037736, Blast_Score=231, Evalue=5e-62,
Organism=Escherichia coli, GI87081870, Length=466, Percent_Identity=26.3948497854077, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 49468; Mature: 49468

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRQKEFVLRTLEERDIRFVRLWFTDVLGYLKSVAIAPAELEGAFEEGIGFDGSSIEGFA
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHH
RVSEADMVARPDPSTFQVLPWADGSGKHHSARMFCDITMPDGSPSWADSRHVLRRQLGKA
HHCCCCCEECCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCC
SDLGFSCYVHPEIEFFLLKPGPNDGTPPVPADNGGYFDQAVHDSAPNFRRHAIDALEQMG
CCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCC
ISVEFSHHEGAPGQQEIDLRYADALSMADNVMTFRYVVKEVALGDGVRASFMPKPFAEYP
CEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCC
GSAMHTHMSLFEGDTNAFHSPDDPLQLSDVAKSFIAGILEHACEISAVTNQWVNSYKRLV
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGGEAPTAASWGAANRSALVRVPMYTPRKASSRRIEVRSPDSACNPYLTFAVLLAAGLRG
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCC
VEKGYVLAPQAEDNVWSLTPEERRAMGYRELPTSLGVALGEMENSELVAEALGEHVFDYF
CCCCEEECCCCCCCEEECCHHHHHHCCHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LRNKRAEWETYRSHVTPYELQAYLSL
HHCCCCHHHHHHHCCCHHHHHEEECC
>Mature Secondary Structure
MDRQKEFVLRTLEERDIRFVRLWFTDVLGYLKSVAIAPAELEGAFEEGIGFDGSSIEGFA
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHH
RVSEADMVARPDPSTFQVLPWADGSGKHHSARMFCDITMPDGSPSWADSRHVLRRQLGKA
HHCCCCCEECCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCC
SDLGFSCYVHPEIEFFLLKPGPNDGTPPVPADNGGYFDQAVHDSAPNFRRHAIDALEQMG
CCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCC
ISVEFSHHEGAPGQQEIDLRYADALSMADNVMTFRYVVKEVALGDGVRASFMPKPFAEYP
CEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCC
GSAMHTHMSLFEGDTNAFHSPDDPLQLSDVAKSFIAGILEHACEISAVTNQWVNSYKRLV
CCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGGEAPTAASWGAANRSALVRVPMYTPRKASSRRIEVRSPDSACNPYLTFAVLLAAGLRG
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCC
VEKGYVLAPQAEDNVWSLTPEERRAMGYRELPTSLGVALGEMENSELVAEALGEHVFDYF
CCCCEEECCCCCCCEEECCHHHHHHCCHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LRNKRAEWETYRSHVTPYELQAYLSL
HHCCCCHHHHHHHCCCHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA