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The map label for this gene is pimB [H]

Identifier: 108800251

GI number: 108800251

Start: 3481825

End: 3482952

Strand: Reverse

Name: pimB [H]

Synonym: Mmcs_3285

Alternate gene names: 108800251

Gene position: 3482952-3481825 (Counterclockwise)

Preceding gene: 108800252

Following gene: 108800249

Centisome position: 61.05

GC content: 72.87

Gene sequence:

>1128_bases
ATGTCCCGAGTCCTGCTGGTCACCAACGACTTTCCGCCGCGCGCCGGTGGTATCCAGAACTACCTCGAGGCCTTCGTCGA
GCATGTCGTGGCGGCAGGTGTGCACGAGGTGACCGTCTACGCCCCGGCGTGGAAGAACGCCGCGGACTACGACCGCGCGG
CGACGTTCGAGGTGGTCCGACACCCCGGCACCCTGATGCTGCCCGAACCGTCGGTGGCCGGTCGTATGCGCGGTCTCATC
GCCGCCCACGACATCGACACCGTGTGGTTCGGCGCGGCGGCGCCGCTGGCCCTGCTGACCCCGATCGCCCGGCGCGCCGG
CGCCGCCCGGGTGATCGCCAGCACGCACGGCCACGAGGTGGGCTGGTCGATGCTGCCGGTGGCGCGGACGGCGTTGCGGC
GCATCGGCGACGACACCGACGTGGTGACCTTCGTCAGTCGCTACACGCGTGGCCGGTTCGCATCGGCGTTCGGGCCGCAC
GCCGCGCTCGAACACCTGCCGCCCGGAGTCGACACCGACCGATTCGCCCCGGATACGTTGGCGCGGGCGGAGTTGCGGGT
CCGTTACGGCCTGGGGGAGCGGCCCGTGGTGGTGTGCCTGTCGCGGCTGGTGCCCCGTAAAGGGCAGGACATGCTGATCA
GGGCGATGCCCGCAATCCGGCGGCGCGTGCCCGGGGCGACGCTGGTGATCGTCGGCGGAGGCCCGTATCGGACCGCGTTG
CAACGCCTGGCCCACGAGCACGGGGTCGCCGAGCACGTGCGGATGACCGGAGGGGTCCCCGGCGACGAACTGCCCGCCCA
CCACGCGATGGGCGATGTGTTCGCGATGCCGTGCCGCACCCGCGGCGCCGGATTGGACGTCGAGGGGCTCGGCATCGTCT
ACCTGGAGGCGTCGGCGAGCGGTGTGCCGGTGGTGGCGGGCCGCTCCGGCGGGGCGCCGGAGACGGTGCGGGACGGGGAG
ACCGGGCTCGTCGTGGACGGCACCGATATCGGCGCGGTTGCCACCGCGGTCGGCGATCTGCTCGCCGACCCCGACCGGGC
CGCCGCGATGGGTGCCGCAGGCAGGCAGTGGGCCGTGGAGAACTGGCAATGGCCCACCCGTGCGGCGCGGCTCGGCGAAC
TGCTCTAA

Upstream 100 bases:

>100_bases
ACCCCGACGTGGCCACCGCGGTGCGCGACACGCTGGGCGCCGGCCTCGACGAGGTGCTGGCCGGCTGGCGACACTGGCCG
CAGGGCTAGCCTGAGCTGCG

Downstream 100 bases:

>100_bases
TCTTCGGCGTCGAGCAGCGCCGCGGCGCGCAACGCCAGCCACAGCGCCGCCACCGCATCGGTTTCGGCGAGGTTGAGCCC
GGTCAGATCCGCGACGCGTT

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MSRVLLVTNDFPPRAGGIQNYLEAFVEHVVAAGVHEVTVYAPAWKNAADYDRAATFEVVRHPGTLMLPEPSVAGRMRGLI
AAHDIDTVWFGAAAPLALLTPIARRAGAARVIASTHGHEVGWSMLPVARTALRRIGDDTDVVTFVSRYTRGRFASAFGPH
AALEHLPPGVDTDRFAPDTLARAELRVRYGLGERPVVVCLSRLVPRKGQDMLIRAMPAIRRRVPGATLVIVGGGPYRTAL
QRLAHEHGVAEHVRMTGGVPGDELPAHHAMGDVFAMPCRTRGAGLDVEGLGIVYLEASASGVPVVAGRSGGAPETVRDGE
TGLVVDGTDIGAVATAVGDLLADPDRAAAMGAAGRQWAVENWQWPTRAARLGELL

Sequences:

>Translated_375_residues
MSRVLLVTNDFPPRAGGIQNYLEAFVEHVVAAGVHEVTVYAPAWKNAADYDRAATFEVVRHPGTLMLPEPSVAGRMRGLI
AAHDIDTVWFGAAAPLALLTPIARRAGAARVIASTHGHEVGWSMLPVARTALRRIGDDTDVVTFVSRYTRGRFASAFGPH
AALEHLPPGVDTDRFAPDTLARAELRVRYGLGERPVVVCLSRLVPRKGQDMLIRAMPAIRRRVPGATLVIVGGGPYRTAL
QRLAHEHGVAEHVRMTGGVPGDELPAHHAMGDVFAMPCRTRGAGLDVEGLGIVYLEASASGVPVVAGRSGGAPETVRDGE
TGLVVDGTDIGAVATAVGDLLADPDRAAAMGAAGRQWAVENWQWPTRAARLGELL
>Mature_374_residues
SRVLLVTNDFPPRAGGIQNYLEAFVEHVVAAGVHEVTVYAPAWKNAADYDRAATFEVVRHPGTLMLPEPSVAGRMRGLIA
AHDIDTVWFGAAAPLALLTPIARRAGAARVIASTHGHEVGWSMLPVARTALRRIGDDTDVVTFVSRYTRGRFASAFGPHA
ALEHLPPGVDTDRFAPDTLARAELRVRYGLGERPVVVCLSRLVPRKGQDMLIRAMPAIRRRVPGATLVIVGGGPYRTALQ
RLAHEHGVAEHVRMTGGVPGDELPAHHAMGDVFAMPCRTRGAGLDVEGLGIVYLEASASGVPVVAGRSGGAPETVRDGET
GLVVDGTDIGAVATAVGDLLADPDRAAAMGAAGRQWAVENWQWPTRAARLGELL

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose resid

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1788357, Length=198, Percent_Identity=28.2828282828283, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32564184, Length=251, Percent_Identity=26.6932270916335, Blast_Score=78, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI9755344, Length=158, Percent_Identity=24.6835443037975, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 39777; Mature: 39646

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVLLVTNDFPPRAGGIQNYLEAFVEHVVAAGVHEVTVYAPAWKNAADYDRAATFEVVR
CCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHH
HPGTLMLPEPSVAGRMRGLIAAHDIDTVWFGAAAPLALLTPIARRAGAARVIASTHGHEV
CCCEEECCCCCHHHHHHHHHEECCCCHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCC
GWSMLPVARTALRRIGDDTDVVTFVSRYTRGRFASAFGPHAALEHLPPGVDTDRFAPDTL
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHCCCCCCCCCCCCHHH
ARAELRVRYGLGERPVVVCLSRLVPRKGQDMLIRAMPAIRRRVPGATLVIVGGGPYRTAL
HHHHEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
QRLAHEHGVAEHVRMTGGVPGDELPAHHAMGDVFAMPCRTRGAGLDVEGLGIVYLEASAS
HHHHHHCCHHHHHHHCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCEEEEEECCCC
GVPVVAGRSGGAPETVRDGETGLVVDGTDIGAVATAVGDLLADPDRAAAMGAAGRQWAVE
CCEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC
NWQWPTRAARLGELL
CCCCHHHHHHHHCCC
>Mature Secondary Structure 
SRVLLVTNDFPPRAGGIQNYLEAFVEHVVAAGVHEVTVYAPAWKNAADYDRAATFEVVR
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHH
HPGTLMLPEPSVAGRMRGLIAAHDIDTVWFGAAAPLALLTPIARRAGAARVIASTHGHEV
CCCEEECCCCCHHHHHHHHHEECCCCHHHHCCCCHHHHHHHHHHHCCCEEEEECCCCCCC
GWSMLPVARTALRRIGDDTDVVTFVSRYTRGRFASAFGPHAALEHLPPGVDTDRFAPDTL
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHCCCCCCCCCCCCHHH
ARAELRVRYGLGERPVVVCLSRLVPRKGQDMLIRAMPAIRRRVPGATLVIVGGGPYRTAL
HHHHEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
QRLAHEHGVAEHVRMTGGVPGDELPAHHAMGDVFAMPCRTRGAGLDVEGLGIVYLEASAS
HHHHHHCCHHHHHHHCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCEEEEEECCCC
GVPVVAGRSGGAPETVRDGETGLVVDGTDIGAVATAVGDLLADPDRAAAMGAAGRQWAVE
CCEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC
NWQWPTRAARLGELL
CCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA