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The map label for this gene is gbh [H]

Identifier: 108800249

GI number: 108800249

Start: 3479269

End: 3480300

Strand: Reverse

Name: gbh [H]

Synonym: Mmcs_3283

Alternate gene names: 108800249

Gene position: 3480300-3479269 (Counterclockwise)

Preceding gene: 108800251

Following gene: 108800247

Centisome position: 61.0

GC content: 69.19

Gene sequence:

>1032_bases
ATGCTCAAACTTCATGGCCGGATTGTGTCAAACGTCGACGCGACACGCATCGGTGCCGGCCGCAGGCTGAGGTCCATGAC
CGGACACATCCTGGGCGCCGTGCCCGCCACCGAGGTGCCCCGCTACGCAGGCAAGAGCACCTTCGCCCGCATCGCCGACA
TCGGGGAGGTCAGTGACTACGACATCGCGATCCTCGGTGTCCCGTTCGACGGCGGCACGTCATACCGGCCCGGTGCGCGC
TTCGGACCCATGGGGGTGCGCCAGGCTGCGCGCACGCTGCGCCCCGGGTACCACGTCGAACTCGGGGTCGCGCCGCTGGA
GCGGGTGCAGGTCGTCGACGCCGGTGACGTCACCGTCACCCCCTACGACATCGCCGAGGCCTGCCGCCAGATCCAGAACC
ACGCCGCCGACATCCTCGGCGGCGGGTCCCGCCGGATCGTGGCCATCGGCGGCGACCACACCATCGCGCTGCCCAACCTG
CGCGCGCTGCACGCGGTGCACGGCCCGGTGGCCCTGGTGCACTTCGATGCCCACCTCGACACCTGGGACACCTACTTCAA
CGCCCCGGTCACGCACGGCACGATCTTCCGTCGGGCGTTCGAGGAAGGCCTGCTGGTCGAGGACCACTCCATCCACGTCG
GTATCCGAGGACCCATCTACGACCAGATCGACCTGCATGAGGACGCGGAGATGGGATTCAAGATCATCCGGGCGGGCGAC
CTGGACGTGATCGGGATCGACGCCGCGGTCGACACCGTGCGCCGCCGGGTCGGGGACGCGCCGGTGTATCTGTCCGTCGA
CATCGACGTGCTCGACCCGGCGTTCGCCCCCGGCACCGGCACCCCGGAATCCGGGGGCCTCACCGCCAGGGAACTGCTGC
GCATGCTGCGGCGGTTGCACGGGCTCAACATCGTCGGTGGTGATGTGGTGGAGGTGGCGCCCGCCTACGACCACGCCGAG
ATCACCTGTGTCGCAGCCGCGACCGTCGTATTCGACCTGGTGTCGCTGATGGTCGCCGGAGGTGCGGGCTAA

Upstream 100 bases:

>100_bases
CCGGTCCAGGCCGGCCGCCCCCGACAGCACGCCGAGACCGAGGTGGGGCATCTCGACGAGGTCAGCGACAGTGAGCGTCA
CACTCGACCCGTTTGTGCAG

Downstream 100 bases:

>100_bases
CCGGTGTAGAGCGCCTCGATGTGGTCGGCGAACTTCTCGGCGACCACCGCGCGCTTGACCTTCAGCGTGGGGGTGAGCTC
ACCGGTGTCCTCGGTGAAGT

Product: agmatinase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLKLHGRIVSNVDATRIGAGRRLRSMTGHILGAVPATEVPRYAGKSTFARIADIGEVSDYDIAILGVPFDGGTSYRPGAR
FGPMGVRQAARTLRPGYHVELGVAPLERVQVVDAGDVTVTPYDIAEACRQIQNHAADILGGGSRRIVAIGGDHTIALPNL
RALHAVHGPVALVHFDAHLDTWDTYFNAPVTHGTIFRRAFEEGLLVEDHSIHVGIRGPIYDQIDLHEDAEMGFKIIRAGD
LDVIGIDAAVDTVRRRVGDAPVYLSVDIDVLDPAFAPGTGTPESGGLTARELLRMLRRLHGLNIVGGDVVEVAPAYDHAE
ITCVAAATVVFDLVSLMVAGGAG

Sequences:

>Translated_343_residues
MLKLHGRIVSNVDATRIGAGRRLRSMTGHILGAVPATEVPRYAGKSTFARIADIGEVSDYDIAILGVPFDGGTSYRPGAR
FGPMGVRQAARTLRPGYHVELGVAPLERVQVVDAGDVTVTPYDIAEACRQIQNHAADILGGGSRRIVAIGGDHTIALPNL
RALHAVHGPVALVHFDAHLDTWDTYFNAPVTHGTIFRRAFEEGLLVEDHSIHVGIRGPIYDQIDLHEDAEMGFKIIRAGD
LDVIGIDAAVDTVRRRVGDAPVYLSVDIDVLDPAFAPGTGTPESGGLTARELLRMLRRLHGLNIVGGDVVEVAPAYDHAE
ITCVAAATVVFDLVSLMVAGGAG
>Mature_343_residues
MLKLHGRIVSNVDATRIGAGRRLRSMTGHILGAVPATEVPRYAGKSTFARIADIGEVSDYDIAILGVPFDGGTSYRPGAR
FGPMGVRQAARTLRPGYHVELGVAPLERVQVVDAGDVTVTPYDIAEACRQIQNHAADILGGGSRRIVAIGGDHTIALPNL
RALHAVHGPVALVHFDAHLDTWDTYFNAPVTHGTIFRRAFEEGLLVEDHSIHVGIRGPIYDQIDLHEDAEMGFKIIRAGD
LDVIGIDAAVDTVRRRVGDAPVYLSVDIDVLDPAFAPGTGTPESGGLTARELLRMLRRLHGLNIVGGDVVEVAPAYDHAE
ITCVAAATVVFDLVSLMVAGGAG

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=304, Percent_Identity=39.1447368421053, Blast_Score=217, Evalue=1e-56,
Organism=Escherichia coli, GI1789306, Length=266, Percent_Identity=45.4887218045113, Blast_Score=205, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 36499; Mature: 36499

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLHGRIVSNVDATRIGAGRRLRSMTGHILGAVPATEVPRYAGKSTFARIADIGEVSDY
CEEECCEEECCCCHHHCCCCHHHHHHHHHHEECCCCHHCCCCCCCHHHHHHHHCCCCCCC
DIAILGVPFDGGTSYRPGARFGPMGVRQAARTLRPGYHVELGVAPLERVQVVDAGDVTVT
CEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCEEEEEECCCEEEC
PYDIAEACRQIQNHAADILGGGSRRIVAIGGDHTIALPNLRALHAVHGPVALVHFDAHLD
CHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCHHHHHCCCCEEEEEEECCCC
TWDTYFNAPVTHGTIFRRAFEEGLLVEDHSIHVGIRGPIYDQIDLHEDAEMGFKIIRAGD
CHHHHCCCCCCHHHHHHHHHHCCCEEECCEEEEEECCCCCCCCCCCCCHHCCEEEEEECC
LDVIGIDAAVDTVRRRVGDAPVYLSVDIDVLDPAFAPGTGTPESGGLTARELLRMLRRLH
CEEEEEHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHC
GLNIVGGDVVEVAPAYDHAEITCVAAATVVFDLVSLMVAGGAG
CCEEECCCEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLKLHGRIVSNVDATRIGAGRRLRSMTGHILGAVPATEVPRYAGKSTFARIADIGEVSDY
CEEECCEEECCCCHHHCCCCHHHHHHHHHHEECCCCHHCCCCCCCHHHHHHHHCCCCCCC
DIAILGVPFDGGTSYRPGARFGPMGVRQAARTLRPGYHVELGVAPLERVQVVDAGDVTVT
CEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCEEEEEECCCEEEC
PYDIAEACRQIQNHAADILGGGSRRIVAIGGDHTIALPNLRALHAVHGPVALVHFDAHLD
CHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCHHHHHCCCCEEEEEEECCCC
TWDTYFNAPVTHGTIFRRAFEEGLLVEDHSIHVGIRGPIYDQIDLHEDAEMGFKIIRAGD
CHHHHCCCCCCHHHHHHHHHHCCCEEECCEEEEEECCCCCCCCCCCCCHHCCEEEEEECC
LDVIGIDAAVDTVRRRVGDAPVYLSVDIDVLDPAFAPGTGTPESGGLTARELLRMLRRLH
CEEEEEHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHC
GLNIVGGDVVEVAPAYDHAEITCVAAATVVFDLVSLMVAGGAG
CCEEECCCEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA