Click here to switch to the map view.

The map label for this gene is mraY [H]

Identifier: 108800225

GI number: 108800225

Start: 3454758

End: 3455837

Strand: Reverse

Name: mraY [H]

Synonym: Mmcs_3259

Alternate gene names: 108800225

Gene position: 3455837-3454758 (Counterclockwise)

Preceding gene: 108800226

Following gene: 108800224

Centisome position: 60.57

GC content: 68.98

Gene sequence:

>1080_bases
ATGAGGCAGATCCTCATCGCCGTCGGCCTCGCGCTGGCGGTGTCGATCCTGCTGACGCCGGTGCTCATCCGGTTGTTCAC
CCGGCAGGGCTTCGGACACGAGATCCGTGAGGACGGCCCGCCGACCCATCACAAGAAGCGCGGCACGCCGTCGATGGGCG
GGGTGGCGATCCTGGCCGGCATCTGGGTCAGCTACCTCGGCACCCACCTGGTCGGGTTGGCGCTCGACGGGGAGGGGCCG
TCGGCCTCGGGTCTGCTGGTCCTCGGCCTGGCCACCGCACTGGGCATCGTGGGCTTCATCGATGACCTGATCAAGATCCG
GCGCGCCCGCAACCTCGGCCTGAACAAGACCGCCAAGACCGTGGGCATCCTGGCGGCCGCCCTGCTGTTCGGGGTGCTGG
CGCTGCAGTTCGGCAACGCCGACGGGCTGACGCCGGGCAGCCCGGAGCTGTCCTATGTGCGCGAGATCGCCACCGTGACA
CTGGCGCCGATGATTTTCGTGCTGTTCTGCGTCGTGCTGGTCAGCGCCTGGTCCAACGCGGTGAACTTCACCGACGGACT
CGACGGTCTGGCCGCGGGCGCGATGGCGATGGTGTGCGCGGCCTACGTGCTGATCACGTTCTGGCAGTACCGCAACGCGT
GCGCGACCAGCCCGGGCCTTGGCTGCTACAACGTGCGCGATCCCCTGGATCTGGCGCTGGTCGCCGCGGCCGCCGCCGGC
GCCTGCATCGGATTCCTGTGGTGGAACGCCGCACCGGCAAAGATCTTCATGGGCGACACCGGATCGCTGGCGCTCGGCGG
CATCATCGCCGGGCTGTCGGTCACCAGCCGCACCGAGATCCTCGCGGTGGTGCTCGGCGCGCTGTTCGTCGCCGAGGTCA
CCTCGGTCGTGGTGCAGATCCTGGCGTTCCGCACCACCGGGCGACGGGTGTTCCGCATGGCCCCGTTCCACCACCACTTC
GAACTCGTGGGTTGGGCCGAGACCACGGTGATCATCCGGTTCTGGTTGCTCACCGCGATCGCCTGCGGGCTGGGCGTGGC
GCTGTTCTACGGCGAGTGGCTCACCGCCGTCGGGGCTTGA

Upstream 100 bases:

>100_bases
TGCAGCCCGGTGATGTCGTGCTGGTGAAGGCGTCGAACTCGGCGGGCCTCGGTGCGCTGGCCGATTCGCTGACCGCCGGA
CGTGACGGGACCGCCACCCG

Downstream 100 bases:

>100_bases
CGTGGCCCGCGCAGTCGTCGAACCGCTGACCCCGGGCGTCCGGGTGCTGATCACCGGCGCCGGGCTGACCGGGCGGTCGG
TCAGCGCGGTGCTCGAGCCG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRQILIAVGLALAVSILLTPVLIRLFTRQGFGHEIREDGPPTHHKKRGTPSMGGVAILAGIWVSYLGTHLVGLALDGEGP
SASGLLVLGLATALGIVGFIDDLIKIRRARNLGLNKTAKTVGILAAALLFGVLALQFGNADGLTPGSPELSYVREIATVT
LAPMIFVLFCVVLVSAWSNAVNFTDGLDGLAAGAMAMVCAAYVLITFWQYRNACATSPGLGCYNVRDPLDLALVAAAAAG
ACIGFLWWNAAPAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEVTSVVVQILAFRTTGRRVFRMAPFHHHF
ELVGWAETTVIIRFWLLTAIACGLGVALFYGEWLTAVGA

Sequences:

>Translated_359_residues
MRQILIAVGLALAVSILLTPVLIRLFTRQGFGHEIREDGPPTHHKKRGTPSMGGVAILAGIWVSYLGTHLVGLALDGEGP
SASGLLVLGLATALGIVGFIDDLIKIRRARNLGLNKTAKTVGILAAALLFGVLALQFGNADGLTPGSPELSYVREIATVT
LAPMIFVLFCVVLVSAWSNAVNFTDGLDGLAAGAMAMVCAAYVLITFWQYRNACATSPGLGCYNVRDPLDLALVAAAAAG
ACIGFLWWNAAPAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEVTSVVVQILAFRTTGRRVFRMAPFHHHF
ELVGWAETTVIIRFWLLTAIACGLGVALFYGEWLTAVGA
>Mature_359_residues
MRQILIAVGLALAVSILLTPVLIRLFTRQGFGHEIREDGPPTHHKKRGTPSMGGVAILAGIWVSYLGTHLVGLALDGEGP
SASGLLVLGLATALGIVGFIDDLIKIRRARNLGLNKTAKTVGILAAALLFGVLALQFGNADGLTPGSPELSYVREIATVT
LAPMIFVLFCVVLVSAWSNAVNFTDGLDGLAAGAMAMVCAAYVLITFWQYRNACATSPGLGCYNVRDPLDLALVAAAAAG
ACIGFLWWNAAPAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEVTSVVVQILAFRTTGRRVFRMAPFHHHF
ELVGWAETTVIIRFWLLTAIACGLGVALFYGEWLTAVGA

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=338, Percent_Identity=37.2781065088757, Blast_Score=190, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 37686; Mature: 37686

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQILIAVGLALAVSILLTPVLIRLFTRQGFGHEIREDGPPTHHKKRGTPSMGGVAILAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHH
IWVSYLGTHLVGLALDGEGPSASGLLVLGLATALGIVGFIDDLIKIRRARNLGLNKTAKT
HHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VGILAAALLFGVLALQFGNADGLTPGSPELSYVREIATVTLAPMIFVLFCVVLVSAWSNA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VNFTDGLDGLAAGAMAMVCAAYVLITFWQYRNACATSPGLGCYNVRDPLDLALVAAAAAG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
ACIGFLWWNAAPAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEVTSVVVQI
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFYGEWLTAVGA
HHHHHCCCHHHHCCCCHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRQILIAVGLALAVSILLTPVLIRLFTRQGFGHEIREDGPPTHHKKRGTPSMGGVAILAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHH
IWVSYLGTHLVGLALDGEGPSASGLLVLGLATALGIVGFIDDLIKIRRARNLGLNKTAKT
HHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VGILAAALLFGVLALQFGNADGLTPGSPELSYVREIATVTLAPMIFVLFCVVLVSAWSNA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VNFTDGLDGLAAGAMAMVCAAYVLITFWQYRNACATSPGLGCYNVRDPLDLALVAAAAAG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
ACIGFLWWNAAPAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEVTSVVVQI
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFYGEWLTAVGA
HHHHHCCCHHHHCCCCHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]