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The map label for this gene is insF1 [H]

Identifier: 108800144

GI number: 108800144

Start: 3370138

End: 3370959

Strand: Reverse

Name: insF1 [H]

Synonym: Mmcs_3178

Alternate gene names: 108800144

Gene position: 3370959-3370138 (Counterclockwise)

Preceding gene: 108800145

Following gene: 108800143

Centisome position: 59.08

GC content: 65.33

Gene sequence:

>822_bases
GTGACGCGCCGGGTACTCAAGCTCGCCCGCCAGCCCTACTACCGCTGGCGGGCAAATCCCATCACCAATGCCGAACTCGT
CGAGGCATACCGCGCCAACGCCCTGTTCGACGCGCACGGCGAGGACCCCGAGTTCGGCTACCGCTACCTCGTCGAGGAGG
CCCGTGAGGCCGGCGAGCCGATGGCCGAGCGCACCGCCTGGCGCATCTGCTCACAGCAGCAGTTGTGGAGCGTGTTCGGC
AAGAAGCGCGGCAAGAACGGCAAACCAGGACCGCCGGTGCACGACGATCTGGTCCAGCGCGACTTCACCGCTGAAACGCC
AAACATGTTGTGGCTCAGCGACATAACTGAGCATTATACCGGCGAGGGCAAGCTCTACCTCTGCGCGATCAAGGATGCAT
TCTCCAACCGCATCGTGGGTTATTCGATCGACTCCCGAATGAAGTCACGCCTGGCGACCGCCGCGCTGCGCAACGCGGTC
GGCCGCCGTGGGGTGGTCGCCGGCTGCGTGGTTCACACGGACAGAGGGTCGCAGTTTCGAAGTCGAAAGTTCGTCCAGGC
CCTGCACCATCACGGCATGGTCGGCTCAATGGGACGTGTCGGCGCGGCCGGCGACAACGCGGCGATGGAGAGCTTCTTCA
GCCTGCTGCAGAAGAACGTCCTCGACCGCCGCCGCTGGGCCACCCGAGAGGAGCTGCGGATCGCCATCGTCACTTGGATC
GAACGCACCTACCACCGACGTCGCCGCCAAGGCGCCCTCGGCCGGTTGACCCCCGTCGAATACGAAGCCATCATGACCAC
GACGGCCAGTCAGGCCGCGTGA

Upstream 100 bases:

>100_bases
TCTTACGGCGGGCAGCGGCGTACTTGTCGCAGGCCAATCTGCCGGGAAAAGGGTCTACCCGCTCGTAAGTGAGCTCGCCG
CCGACGGGATTCCCGTCGCG

Downstream 100 bases:

>100_bases
CCGAAATTGTCACCTGATCGTGCAGCAGACCCACTTCCTGATAGAGCTTGGCACAGGCCTCTTTGGTAGGTGCACCGTCC
TCGCGTGAGTCAGATGCATC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MTRRVLKLARQPYYRWRANPITNAELVEAYRANALFDAHGEDPEFGYRYLVEEAREAGEPMAERTAWRICSQQQLWSVFG
KKRGKNGKPGPPVHDDLVQRDFTAETPNMLWLSDITEHYTGEGKLYLCAIKDAFSNRIVGYSIDSRMKSRLATAALRNAV
GRRGVVAGCVVHTDRGSQFRSRKFVQALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLDRRRWATREELRIAIVTWI
ERTYHRRRRQGALGRLTPVEYEAIMTTTASQAA

Sequences:

>Translated_273_residues
MTRRVLKLARQPYYRWRANPITNAELVEAYRANALFDAHGEDPEFGYRYLVEEAREAGEPMAERTAWRICSQQQLWSVFG
KKRGKNGKPGPPVHDDLVQRDFTAETPNMLWLSDITEHYTGEGKLYLCAIKDAFSNRIVGYSIDSRMKSRLATAALRNAV
GRRGVVAGCVVHTDRGSQFRSRKFVQALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLDRRRWATREELRIAIVTWI
ERTYHRRRRQGALGRLTPVEYEAIMTTTASQAA
>Mature_272_residues
TRRVLKLARQPYYRWRANPITNAELVEAYRANALFDAHGEDPEFGYRYLVEEAREAGEPMAERTAWRICSQQQLWSVFGK
KRGKNGKPGPPVHDDLVQRDFTAETPNMLWLSDITEHYTGEGKLYLCAIKDAFSNRIVGYSIDSRMKSRLATAALRNAVG
RRGVVAGCVVHTDRGSQFRSRKFVQALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLDRRRWATREELRIAIVTWIE
RTYHRRRRQGALGRLTPVEYEAIMTTTASQAA

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=230, Percent_Identity=30.4347826086957, Blast_Score=95, Evalue=5e-20,
Organism=Escherichia coli, GI1788405, Length=264, Percent_Identity=32.9545454545455, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1787263, Length=264, Percent_Identity=32.9545454545455, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1786753, Length=264, Percent_Identity=32.9545454545455, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1786570, Length=264, Percent_Identity=32.9545454545455, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1786490, Length=264, Percent_Identity=32.9545454545455, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1789981, Length=222, Percent_Identity=31.0810810810811, Blast_Score=114, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31087; Mature: 30956

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRVLKLARQPYYRWRANPITNAELVEAYRANALFDAHGEDPEFGYRYLVEEAREAGEP
CCHHHHHHHHCCHHEECCCCCCCHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHCCC
MAERTAWRICSQQQLWSVFGKKRGKNGKPGPPVHDDLVQRDFTAETPNMLWLSDITEHYT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCEEEHHHHHHHHC
GEGKLYLCAIKDAFSNRIVGYSIDSRMKSRLATAALRNAVGRRGVVAGCVVHTDRGSQFR
CCCCEEEEEECHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
SRKFVQALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLDRRRWATREELRIAIVTWI
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ERTYHRRRRQGALGRLTPVEYEAIMTTTASQAA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRRVLKLARQPYYRWRANPITNAELVEAYRANALFDAHGEDPEFGYRYLVEEAREAGEP
CHHHHHHHHCCHHEECCCCCCCHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHCCC
MAERTAWRICSQQQLWSVFGKKRGKNGKPGPPVHDDLVQRDFTAETPNMLWLSDITEHYT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCEEEHHHHHHHHC
GEGKLYLCAIKDAFSNRIVGYSIDSRMKSRLATAALRNAVGRRGVVAGCVVHTDRGSQFR
CCCCEEEEEECHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHH
SRKFVQALHHHGMVGSMGRVGAAGDNAAMESFFSLLQKNVLDRRRWATREELRIAIVTWI
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ERTYHRRRRQGALGRLTPVEYEAIMTTTASQAA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]