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The map label for this gene is 108800064

Identifier: 108800064

GI number: 108800064

Start: 3276215

End: 3277705

Strand: Reverse

Name: 108800064

Synonym: Mmcs_3098

Alternate gene names: NA

Gene position: 3277705-3276215 (Counterclockwise)

Preceding gene: 108800066

Following gene: 108800063

Centisome position: 57.45

GC content: 67.47

Gene sequence:

>1491_bases
ATGCGAGTGGAACGCCTGCAGACCTTCGCCTCGACGCTGCCCGCCGATGACGACCATCCGTACCGCACCGGGCCGTGGCG
CCCCCAGGTCACCGAGTGGCGGGCCGACGACCTCGAGGTCGTCGCCGGCGAGGTGCCTGCCGATCTCGACGGCATGTACC
TGCGCAACACGGAGAACCCGCTGCATCCGGCCGCGACGGCCTACCACCCGTTCGACGGTGACGGGATGATCCACATCGTC
GAGTTCGGCGGGGGAAAAGCGGCCTACCGCAACCGCTTCGTCCGCACCGACGGCTTCCTCGCCGAGAACGAGGCCGGGGG
ACCGCTGTGGGCCGGGTTCATCGAGATGCCCTCGGCCGCCAAACGCGCCGACGGCTGGGGCGCGCGCACGCGGATGAAGG
ACGCGTCGAGCACTGACGTCGTCGTCCACCGCGGGACGGCGCTGACCAGTTTCTACATGTGCGGCGACCTCTACCAGGTC
GACCCGTACACCGCCGACACCCTCGGCAAGGAGACCTGGCACGGCGACTTCCCGGACTGGGGGGTGTCGGCGCATCCCAA
GATCGACCCGGTCACCGGGGAGCTGCTGTTCTTCAGCTACAGCAAGGAAGCGCCTCATCTGCGCTACGGCGTGGTCGACA
AGGACGCGAACCTGGTGCACCACACCGACGTCGCGCTGCCCGGGCCGCGGATGCCGCACGATATGGCGTTCACCGAGAAC
TACGTGATCCTCAACGACTTCCCGCTGTTCTGGGAGCCGTCGCTGCTGAAGCAGGACATCCACGCACCGGTCTTCCACCG
CGACATGCCGTCGCGTTTCGCCGTGCTGCCCCGCCGCGGTGACCAGTCGCAGGTGCGGTGGTTCGAGACCGACCCGACGT
ATGCCCTGCACTTCGTCAACGCCTACGAGGACGGTGACGAGATCGTGCTCGACGGGTTCTTCCAGGACAACCCGTCACCG
TCGACGAAGGGCGCGAAGTCGTTGGAGGACGCGGCCTTCCGCTACCTGGCACTCGACGGGTTCGAATCGCACCTGCACCG
CTGGCGGTTCAACCTCGCCACGGGGGCGGCCACGGAGGAACGGCTGTCGGACAGCCTCACCGAATTCGGCATGATGAACG
GTGACTACCAGACCCGGCGGCACCGCTACGTGTACGCCGCCACCGGCAAACCGGGCTGGTTCCTGTTCGACGGGCTGGTC
AAACACGATCTGCGCGACGGTACCGAGGAGCGGATCACGTTCGGCGACGGCGTGTTCGGCAGCGAGACCGCGATGGCGCC
GCGTCAGGACGGCACCGCCGAGGACGACGGCTACCTCGTCACCCTGACCACGGACATGAACGACGACGCCTCCTACTGCT
TGGTGTTCGATGCCGCGCGGATCGCCGACGGTCCGGTGTGCAAGCTGCGGCTTCCTGAAAGAATCTGCAGCGGAACACAT
TCGACGTGGGTGTCCGGGGCTGAGCTGCGGCGCTGGCACAGCCCGCGGTGA

Upstream 100 bases:

>100_bases
GCGGGCGAAATCGCTCTGGTACGCGCCGAGGATCCAGATGTCCTGCATGACGCCTATAGTTCAATTGACAGAGTCACTCT
GTCAACTGTAGTTTTCGGCC

Downstream 100 bases:

>100_bases
CCGGGGGCAGCGGGCCGGTCAACGCCGTCGGCCGGATGCTCGGCCTGCTCGGCGACGAGTGGACGCTGCTCCTCGTCCGC
GAAACCCTCCTGGGCGCACG

Product: carotenoid oxygenase

Products: NA

Alternate protein names: ACO; 8'-apo-beta-carotenal 15,15'-oxygenase; Diox1 [H]

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MRVERLQTFASTLPADDDHPYRTGPWRPQVTEWRADDLEVVAGEVPADLDGMYLRNTENPLHPAATAYHPFDGDGMIHIV
EFGGGKAAYRNRFVRTDGFLAENEAGGPLWAGFIEMPSAAKRADGWGARTRMKDASSTDVVVHRGTALTSFYMCGDLYQV
DPYTADTLGKETWHGDFPDWGVSAHPKIDPVTGELLFFSYSKEAPHLRYGVVDKDANLVHHTDVALPGPRMPHDMAFTEN
YVILNDFPLFWEPSLLKQDIHAPVFHRDMPSRFAVLPRRGDQSQVRWFETDPTYALHFVNAYEDGDEIVLDGFFQDNPSP
STKGAKSLEDAAFRYLALDGFESHLHRWRFNLATGAATEERLSDSLTEFGMMNGDYQTRRHRYVYAATGKPGWFLFDGLV
KHDLRDGTEERITFGDGVFGSETAMAPRQDGTAEDDGYLVTLTTDMNDDASYCLVFDAARIADGPVCKLRLPERICSGTH
STWVSGAELRRWHSPR

Sequences:

>Translated_496_residues
MRVERLQTFASTLPADDDHPYRTGPWRPQVTEWRADDLEVVAGEVPADLDGMYLRNTENPLHPAATAYHPFDGDGMIHIV
EFGGGKAAYRNRFVRTDGFLAENEAGGPLWAGFIEMPSAAKRADGWGARTRMKDASSTDVVVHRGTALTSFYMCGDLYQV
DPYTADTLGKETWHGDFPDWGVSAHPKIDPVTGELLFFSYSKEAPHLRYGVVDKDANLVHHTDVALPGPRMPHDMAFTEN
YVILNDFPLFWEPSLLKQDIHAPVFHRDMPSRFAVLPRRGDQSQVRWFETDPTYALHFVNAYEDGDEIVLDGFFQDNPSP
STKGAKSLEDAAFRYLALDGFESHLHRWRFNLATGAATEERLSDSLTEFGMMNGDYQTRRHRYVYAATGKPGWFLFDGLV
KHDLRDGTEERITFGDGVFGSETAMAPRQDGTAEDDGYLVTLTTDMNDDASYCLVFDAARIADGPVCKLRLPERICSGTH
STWVSGAELRRWHSPR
>Mature_496_residues
MRVERLQTFASTLPADDDHPYRTGPWRPQVTEWRADDLEVVAGEVPADLDGMYLRNTENPLHPAATAYHPFDGDGMIHIV
EFGGGKAAYRNRFVRTDGFLAENEAGGPLWAGFIEMPSAAKRADGWGARTRMKDASSTDVVVHRGTALTSFYMCGDLYQV
DPYTADTLGKETWHGDFPDWGVSAHPKIDPVTGELLFFSYSKEAPHLRYGVVDKDANLVHHTDVALPGPRMPHDMAFTEN
YVILNDFPLFWEPSLLKQDIHAPVFHRDMPSRFAVLPRRGDQSQVRWFETDPTYALHFVNAYEDGDEIVLDGFFQDNPSP
STKGAKSLEDAAFRYLALDGFESHLHRWRFNLATGAATEERLSDSLTEFGMMNGDYQTRRHRYVYAATGKPGWFLFDGLV
KHDLRDGTEERITFGDGVFGSETAMAPRQDGTAEDDGYLVTLTTDMNDDASYCLVFDAARIADGPVCKLRLPERICSGTH
STWVSGAELRRWHSPR

Specific function: Cleaves a number of carotenals and carotenols in the all-trans configuration at the 15-15' double bond producing retinal or retinol, respectively. Also shows activity toward lycopenals and the corresponding alcohols. Does not cleave beta- carotene or lyco

COG id: COG3670

COG function: function code Q; Lignostilbene-alpha,beta-dioxygenase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004294 [H]

Pfam domain/function: PF03055 RPE65 [H]

EC number: =1.14.99.41 [H]

Molecular weight: Translated: 55758; Mature: 55758

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVERLQTFASTLPADDDHPYRTGPWRPQVTEWRADDLEVVAGEVPADLDGMYLRNTENP
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCC
LHPAATAYHPFDGDGMIHIVEFGGGKAAYRNRFVRTDGFLAENEAGGPLWAGFIEMPSAA
CCCCCCCCCCCCCCCEEEEEEECCCCHHHHCCEEECCCEEECCCCCCCEEEHHHHCCCHH
KRADGWGARTRMKDASSTDVVVHRGTALTSFYMCGDLYQVDPYTADTLGKETWHGDFPDW
HHCCCCCCCCCCCCCCCCCEEEECCCHHEEHHHCCCEEEECCCCHHHCCCCCCCCCCCCC
GVSAHPKIDPVTGELLFFSYSKEAPHLRYGVVDKDANLVHHTDVALPGPRMPHDMAFTEN
CCCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCEECCC
YVILNDFPLFWEPSLLKQDIHAPVFHRDMPSRFAVLPRRGDQSQVRWFETDPTYALHFVN
EEEEECCCCCCCCHHHHHHCCCCHHHCCCCCCEEEECCCCCCCCEEEEECCCCEEEEEEE
AYEDGDEIVLDGFFQDNPSPSTKGAKSLEDAAFRYLALDGFESHLHRWRFNLATGAATEE
CCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHEEEEEECCHHHHHHHEEEEECCCCCHHH
RLSDSLTEFGMMNGDYQTRRHRYVYAATGKPGWFLFDGLVKHDLRDGTEERITFGDGVFG
HHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEHHHHHHHHHCCCCCCEEEECCCCCC
SETAMAPRQDGTAEDDGYLVTLTTDMNDDASYCLVFDAARIADGPVCKLRLPERICSGTH
CCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEHHHCCCCCEEEEECCHHHHCCCC
STWVSGAELRRWHSPR
HHHCCCHHHHHCCCCC
>Mature Secondary Structure
MRVERLQTFASTLPADDDHPYRTGPWRPQVTEWRADDLEVVAGEVPADLDGMYLRNTENP
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCC
LHPAATAYHPFDGDGMIHIVEFGGGKAAYRNRFVRTDGFLAENEAGGPLWAGFIEMPSAA
CCCCCCCCCCCCCCCEEEEEEECCCCHHHHCCEEECCCEEECCCCCCCEEEHHHHCCCHH
KRADGWGARTRMKDASSTDVVVHRGTALTSFYMCGDLYQVDPYTADTLGKETWHGDFPDW
HHCCCCCCCCCCCCCCCCCEEEECCCHHEEHHHCCCEEEECCCCHHHCCCCCCCCCCCCC
GVSAHPKIDPVTGELLFFSYSKEAPHLRYGVVDKDANLVHHTDVALPGPRMPHDMAFTEN
CCCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCEECCC
YVILNDFPLFWEPSLLKQDIHAPVFHRDMPSRFAVLPRRGDQSQVRWFETDPTYALHFVN
EEEEECCCCCCCCHHHHHHCCCCHHHCCCCCCEEEECCCCCCCCEEEEECCCCEEEEEEE
AYEDGDEIVLDGFFQDNPSPSTKGAKSLEDAAFRYLALDGFESHLHRWRFNLATGAATEE
CCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHEEEEEECCHHHHHHHEEEEECCCCCHHH
RLSDSLTEFGMMNGDYQTRRHRYVYAATGKPGWFLFDGLVKHDLRDGTEERITFGDGVFG
HHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEHHHHHHHHHCCCCCCEEEECCCCCC
SETAMAPRQDGTAEDDGYLVTLTTDMNDDASYCLVFDAARIADGPVCKLRLPERICSGTH
CCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEHHHCCCCCEEEEECCHHHHCCCC
STWVSGAELRRWHSPR
HHHCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]