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The map label for this gene is infC [H]

Identifier: 108799947

GI number: 108799947

Start: 3146414

End: 3147130

Strand: Reverse

Name: infC [H]

Synonym: Mmcs_2981

Alternate gene names: 108799947

Gene position: 3147130-3146414 (Counterclockwise)

Preceding gene: 108799954

Following gene: 108799946

Centisome position: 55.16

GC content: 65.13

Gene sequence:

>717_bases
GTGCTGTTGGCACGGGCGGCGGAAGCCGTGATCGGTCGGCAACGGGCCCTGCAGTGCAGGGCCTTCCTGCTCTCGCGGGC
AGGTGCGGAATGGGCCAGTGGACTCCCTGGAGAACACAACATAGGAGGCCCCATCAGCACTGAGACCCGCGTCAACGAGC
GCATCCGCGTACCTGAAGTTCGCCTGATCGGACCGGGCGGTGAACAGGTAGGCATCGTGCGCATCGAAGATGCACTCCGC
GTCGCCGCGGATGCCGATCTCGATCTCGTCGAAGTTGCACCGGACGCCAAGCCGCCCGTCTGCAAGATCATGGACTACGG
AAAGTTCAAGTACGAGACGGCACAGAAGGCGCGCGAGTCTCGCAAGAACCAGCAGCAGACCGTCGTCAAGGAACAGAAGC
TCCGTCCCAAGATCGACCCGCACGATTACGAGACCAAGAAGGGTCACGTCATCCGCTTCCTCGAGGCCGGGTCCAAGGTC
AAGGTGACGATCATGTTCCGCGGACGTGAGCAGTCGCGGCCCGAACTGGGCTTCCGACTCCTGCAGCGCCTGGGCGCCGA
CGTGGCCGAGTACGGCTTCGTCGAGACGTCCGCGAAGCAGGACGGACGCAACATGACGATGGTGCTGGCCCCGCATCGCG
GCGCGAAGACTCGCGCCAAAGCGGCGGAGCAAGCAGAACGTCCCCGCGAGTCGGCCCCCGGCCCGGACGCCACGTAG

Upstream 100 bases:

>100_bases
ACCGTCCTGGCTGACGTCAGGACAGTAAGTGGAGTCCCACTCCCACCGCTGGCCAACCAGGCACAGCGGTCCGGTCACCG
GCATCCAGTATGCCGGTTCT

Downstream 100 bases:

>100_bases
CACTGCCCGACACCGAACAGAATCAAGAGGACACCCATGCCCAAGGCCAAGACCCACAGCGGCGCGTCCAAGCGCTTCCG
GCGCACCGGCACCGGAAAGA

Product: translation initiation factor 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MLLARAAEAVIGRQRALQCRAFLLSRAGAEWASGLPGEHNIGGPISTETRVNERIRVPEVRLIGPGGEQVGIVRIEDALR
VAADADLDLVEVAPDAKPPVCKIMDYGKFKYETAQKARESRKNQQQTVVKEQKLRPKIDPHDYETKKGHVIRFLEAGSKV
KVTIMFRGREQSRPELGFRLLQRLGADVAEYGFVETSAKQDGRNMTMVLAPHRGAKTRAKAAEQAERPRESAPGPDAT

Sequences:

>Translated_238_residues
MLLARAAEAVIGRQRALQCRAFLLSRAGAEWASGLPGEHNIGGPISTETRVNERIRVPEVRLIGPGGEQVGIVRIEDALR
VAADADLDLVEVAPDAKPPVCKIMDYGKFKYETAQKARESRKNQQQTVVKEQKLRPKIDPHDYETKKGHVIRFLEAGSKV
KVTIMFRGREQSRPELGFRLLQRLGADVAEYGFVETSAKQDGRNMTMVLAPHRGAKTRAKAAEQAERPRESAPGPDAT
>Mature_238_residues
MLLARAAEAVIGRQRALQCRAFLLSRAGAEWASGLPGEHNIGGPISTETRVNERIRVPEVRLIGPGGEQVGIVRIEDALR
VAADADLDLVEVAPDAKPPVCKIMDYGKFKYETAQKARESRKNQQQTVVKEQKLRPKIDPHDYETKKGHVIRFLEAGSKV
KVTIMFRGREQSRPELGFRLLQRLGADVAEYGFVETSAKQDGRNMTMVLAPHRGAKTRAKAAEQAERPRESAPGPDAT

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=166, Percent_Identity=48.7951807228916, Blast_Score=146, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 26300; Mature: 26300

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLARAAEAVIGRQRALQCRAFLLSRAGAEWASGLPGEHNIGGPISTETRVNERIRVPEV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCHHHCCCCCCCEE
RLIGPGGEQVGIVRIEDALRVAADADLDLVEVAPDAKPPVCKIMDYGKFKYETAQKARES
EEECCCCCEEEEEEEHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHH
RKNQQQTVVKEQKLRPKIDPHDYETKKGHVIRFLEAGSKVKVTIMFRGREQSRPELGFRL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHH
LQRLGADVAEYGFVETSAKQDGRNMTMVLAPHRGAKTRAKAAEQAERPRESAPGPDAT
HHHHCCHHHHHCCEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCHHCCCCCCCC
>Mature Secondary Structure
MLLARAAEAVIGRQRALQCRAFLLSRAGAEWASGLPGEHNIGGPISTETRVNERIRVPEV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCHHHCCCCCCCEE
RLIGPGGEQVGIVRIEDALRVAADADLDLVEVAPDAKPPVCKIMDYGKFKYETAQKARES
EEECCCCCEEEEEEEHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHH
RKNQQQTVVKEQKLRPKIDPHDYETKKGHVIRFLEAGSKVKVTIMFRGREQSRPELGFRL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHH
LQRLGADVAEYGFVETSAKQDGRNMTMVLAPHRGAKTRAKAAEQAERPRESAPGPDAT
HHHHCCHHHHHCCEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]