Click here to switch to the map view.

The map label for this gene is argJ [H]

Identifier: 108799937

GI number: 108799937

Start: 3135615

End: 3136820

Strand: Reverse

Name: argJ [H]

Synonym: Mmcs_2971

Alternate gene names: 108799937

Gene position: 3136820-3135615 (Counterclockwise)

Preceding gene: 108799938

Following gene: 108799936

Centisome position: 54.98

GC content: 71.72

Gene sequence:

>1206_bases
GTGACGGGCTCCGCACCGCTGATCCGCACCCAGGGCGTCACCGCCCCCGCCGGCTTCCGGGCCGCCGGAATCGCGGCCGG
CATCAAGGCGTCGGGTGCGCTCGACCTCGCCCTCGTGCTCAACGAAGGCCCCGACCACACCGCGGCGGGTGTGTTCACCC
GCAACCAGGTCCAGGCCGCACCGGTGTTGTGGAGCCGGCAGGTGCTCACCACCGGGCGGCTGCGTGCCGTCGTCCTCAAT
TCCGGCGGCGCCAACGCCTGCACCGGCCCGCTCGGGTTCCAGGACACCCACGCCACCGCCGAGGCGGTCGCCGCGGCGCT
GTCCGACTGGGGTTCGGAGACCGGCGCCATCGAGGTCGCGGTCTGCTCGACCGGTCTGATCGGCGACCGGCTGCCGATGG
ACAAGGTCCTCGCCGGGGTCACCGAGGTGGTCCACGAGATGGCCGGCGGGCTGTCCGGTGGCGAGGAAGCCGCCCGCGCC
ATCATGACCACCGACACCGTGCCGAAACAGGTTGCGCTGCACCACCCCGACAACTGGACCGTCGGCGGGATGGCCAAGGG
CGCGGGCATGATGGCGCCGTCGCTGGCCACGATGCTGTGCGTCCTGACCACCGACGCCGTCGCCGGTTCCGAGGCCCTCG
ACACCGCGCTGCGCCGGGCGGCGAAACGCACCTTCGACCGTCTCGACATCGACGGCAGCTGCTCGACGAACGACACCGTG
CTCCTGCTCGCCTCCGGCGCCAGCGAGATCACGCCCAGCCAGGAGGAGCTCGACGAGGCGGTCCTGCGGGTGTGTGACGA
CCTGTGCGCCCAGCTGCAGGCCGATGCCGAAGGCGTCACCAAACGCATCGCCATCACCGTCACCGGTGCGCCGACCGAGG
ACGACGCGCTCGTCGCCGCCCGGCTGCTCGCCCGGGACAGCCTGGTCAAGACCGCGCTGTTCGGCTCCGACCCGAACTGG
GGGCGGGTGCTCGCCGCGGTCGGGATGGTGCCGTTCACCATCGACCCGAACCGGATCACCGTGTCGTTCAACGGTTCCCC
GACGTTTGCCAACGGCGCCGGGACACCCGGTGCCCGCGAGGTGGATCTGACCGGCTCCGACATCGACGTCGCCGTCGACC
TCGGCCTCGGCGCGGGGCAGGCGACGGTGCGCACCACCGATCTGTCGCACGCGTACGTCGAAGAGAACTCGGCGTACAGC
TCATGA

Upstream 100 bases:

>100_bases
ACAACTTGACCAAGGGGACCGGTGGGGCGGCGGTGCAGTCGATGAACCTGGCGCTGGGTTGGCCGGAGACCGAGGGCCTG
TCGATCGTGGGGGTCGCGCC

Downstream 100 bases:

>100_bases
CCGCCGCGACACACACCAAGGCGCAGGTGCTCGCCGCGGCGCTGCCGTGGCTCAAACAACTGCACGGCAAGATCGTCGTG
GTGAAGTACGGCGGAAACGC

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTGSAPLIRTQGVTAPAGFRAAGIAAGIKASGALDLALVLNEGPDHTAAGVFTRNQVQAAPVLWSRQVLTTGRLRAVVLN
SGGANACTGPLGFQDTHATAEAVAAALSDWGSETGAIEVAVCSTGLIGDRLPMDKVLAGVTEVVHEMAGGLSGGEEAARA
IMTTDTVPKQVALHHPDNWTVGGMAKGAGMMAPSLATMLCVLTTDAVAGSEALDTALRRAAKRTFDRLDIDGSCSTNDTV
LLLASGASEITPSQEELDEAVLRVCDDLCAQLQADAEGVTKRIAITVTGAPTEDDALVAARLLARDSLVKTALFGSDPNW
GRVLAAVGMVPFTIDPNRITVSFNGSPTFANGAGTPGAREVDLTGSDIDVAVDLGLGAGQATVRTTDLSHAYVEENSAYS
S

Sequences:

>Translated_401_residues
MTGSAPLIRTQGVTAPAGFRAAGIAAGIKASGALDLALVLNEGPDHTAAGVFTRNQVQAAPVLWSRQVLTTGRLRAVVLN
SGGANACTGPLGFQDTHATAEAVAAALSDWGSETGAIEVAVCSTGLIGDRLPMDKVLAGVTEVVHEMAGGLSGGEEAARA
IMTTDTVPKQVALHHPDNWTVGGMAKGAGMMAPSLATMLCVLTTDAVAGSEALDTALRRAAKRTFDRLDIDGSCSTNDTV
LLLASGASEITPSQEELDEAVLRVCDDLCAQLQADAEGVTKRIAITVTGAPTEDDALVAARLLARDSLVKTALFGSDPNW
GRVLAAVGMVPFTIDPNRITVSFNGSPTFANGAGTPGAREVDLTGSDIDVAVDLGLGAGQATVRTTDLSHAYVEENSAYS
S
>Mature_400_residues
TGSAPLIRTQGVTAPAGFRAAGIAAGIKASGALDLALVLNEGPDHTAAGVFTRNQVQAAPVLWSRQVLTTGRLRAVVLNS
GGANACTGPLGFQDTHATAEAVAAALSDWGSETGAIEVAVCSTGLIGDRLPMDKVLAGVTEVVHEMAGGLSGGEEAARAI
MTTDTVPKQVALHHPDNWTVGGMAKGAGMMAPSLATMLCVLTTDAVAGSEALDTALRRAAKRTFDRLDIDGSCSTNDTVL
LLASGASEITPSQEELDEAVLRVCDDLCAQLQADAEGVTKRIAITVTGAPTEDDALVAARLLARDSLVKTALFGSDPNWG
RVLAAVGMVPFTIDPNRITVSFNGSPTFANGAGTPGAREVDLTGSDIDVAVDLGLGAGQATVRTTDLSHAYVEENSAYSS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=420, Percent_Identity=39.0476190476191, Blast_Score=243, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 40877; Mature: 40746

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSAPLIRTQGVTAPAGFRAAGIAAGIKASGALDLALVLNEGPDHTAAGVFTRNQVQAA
CCCCCCEEEECCCCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEECCCCEEC
PVLWSRQVLTTGRLRAVVLNSGGANACTGPLGFQDTHATAEAVAAALSDWGSETGAIEVA
CHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
VCSTGLIGDRLPMDKVLAGVTEVVHEMAGGLSGGEEAARAIMTTDTVPKQVALHHPDNWT
EECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCE
VGGMAKGAGMMAPSLATMLCVLTTDAVAGSEALDTALRRAAKRTFDRLDIDGSCSTNDTV
ECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
LLLASGASEITPSQEELDEAVLRVCDDLCAQLQADAEGVTKRIAITVTGAPTEDDALVAA
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHH
RLLARDSLVKTALFGSDPNWGRVLAAVGMVPFTIDPNRITVSFNGSPTFANGAGTPGARE
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEECCCEEEEEECCCCCCCCCCCCCCCEE
VDLTGSDIDVAVDLGLGAGQATVRTTDLSHAYVEENSAYSS
EEECCCCEEEEEEECCCCCCCEEEEECCCHHHHCCCCCCCC
>Mature Secondary Structure 
TGSAPLIRTQGVTAPAGFRAAGIAAGIKASGALDLALVLNEGPDHTAAGVFTRNQVQAA
CCCCCEEEECCCCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEECCCCEEC
PVLWSRQVLTTGRLRAVVLNSGGANACTGPLGFQDTHATAEAVAAALSDWGSETGAIEVA
CHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
VCSTGLIGDRLPMDKVLAGVTEVVHEMAGGLSGGEEAARAIMTTDTVPKQVALHHPDNWT
EECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCE
VGGMAKGAGMMAPSLATMLCVLTTDAVAGSEALDTALRRAAKRTFDRLDIDGSCSTNDTV
ECCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEE
LLLASGASEITPSQEELDEAVLRVCDDLCAQLQADAEGVTKRIAITVTGAPTEDDALVAA
EEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHH
RLLARDSLVKTALFGSDPNWGRVLAAVGMVPFTIDPNRITVSFNGSPTFANGAGTPGARE
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEECCCEEEEEECCCCCCCCCCCCCCCEE
VDLTGSDIDVAVDLGLGAGQATVRTTDLSHAYVEENSAYSS
EEECCCCEEEEEEECCCCCCCEEEEECCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]