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The map label for this gene is secA2

Identifier: 108799816

GI number: 108799816

Start: 3013480

End: 3015804

Strand: Reverse

Name: secA2

Synonym: Mmcs_2850

Alternate gene names: 108799816

Gene position: 3015804-3013480 (Counterclockwise)

Preceding gene: 108799817

Following gene: 108799815

Centisome position: 52.86

GC content: 68.56

Gene sequence:

>2325_bases
GTGCCCAAGACGACTACACGCACCCCCGGCCGCCTGAGCGGCAAGTTCTGGAAACTGCTCGGCGCCGCCACCGAGAAGAA
CCAGGGCCGGTCGCTGGCACAGGTCAAGGCGTCCGCGGACTACGAGACCAAGGCCGCCGACCTCGACGACGAACAGCTGC
GCAAAGCCGCCGAGTTGCTGCGGCTCGAGGATCTCTCTGAGTCGGCCGACATCCCGCAGTTCCTGGCCATCGCGCGCGAA
GCCGCCGAGCGCTCCACCTCGCTGCGTCCGTTCGACGTCCAGCTGCTCGGCGCGCTGCGCATGCTCGCCGGCGACGTCGT
CGAGATGGCCACCGGTGAGGGCAAGACGCTGTCCGGCGCGATCGCCGCGGCGGGCTACGCCCTGGGCGGCCGCAGCGTGC
ACGTCATCACGATCAACGACTACCTCGCCCGCCGCGACGCCGAATGGATGGGCCCGCTGATCGAGGCGCTGGGCCTAACC
GTCGGCTGGATCACCGCCGAGTCGACGGCCGAGGAGCGCCGCAGGGCCTACACCTGCGACGTCACCTACGCCTCGGTGAA
CGAGATCGGTTTCGACGTGCTCCGCGACCAGCTCGTCACCGATGTCGCCGACCTGGTGTCGCCGAACCCCGACGTCGCGC
TCATCGACGAAGCCGACTCCGTCCTGGTCGACGAGGCACTCGTCCCGCTGGTGCTCGCCGGCACCAGCCACCGCGAGACC
CCGCGCGTCGAGCTGATCCGCATGGTCGGTGAACTGACCCCCGGCCGCGACTTCGACACCGACACCGACAGCCGCAACGT
GCACCTCACCGACGAGGGCGCCCGCAAACTCGAGGCCAAGCTGGGCGGCATCGACCTCTACTCCGAAGAGCATGTCGGCA
CGACGCTGACCGAGGTGAACGTCGCCCTGCACGCCCATGTGCTGCTGCAGCGCGACGTGCACTACATCGTGCGCGACGAC
GCCGTCCACCTGATCAACTCCTCCCGCGGACGCATCGCCCAGCTGCAGCGCTGGCCCGACGGTCTGCAGGCGGCCGTCGA
GGCGAAGGAGGGCATCGCGACCACCGAGACCGGTGAGGTGCTCGACACCATCACCGTGCAGGCGTTGATCAACCGGTATC
CGACGGTGTGCGGTATGACCGGCACCGCGCTGGCCGCCGGTGAACAGCTCCGCCAGTTCTACAAGCTGGGCGTGTCGCCG
ATCGAGCCGAACAAGCCCAACATCCGCGAAGACGAATCCGACCGGGTGTACGTCACCGCGGCGGCCAAGATCGACGCGAT
CATCGAGCACATCGAAGAGGTGCACAAGACCGGTCAACCGGTCCTCGTCGGCACCCACGACGTCGCCGAATCCGAAGAGC
TGCACGAGAAGCTGGTCAAGCGCGGGGTGCCCGCGGTGGTGCTCAACGCCAAGAACGACGCCGAGGAGGCCCGCGTCATC
GCCGAGGCCGGCAAGCTCGGCGCGGTCACCGTATCCACCCAGATGGCCGGACGTGGAACCGACATCCGGCTGGGCGGGTC
GGACGAAGGTGACCACGATGAAGTGGCCGAACTCGGCGGCCTGCACGTCGTCGGCACCGGCCGCCACAACACCCAGCGAC
TCGACAACCAGTTGCGCGGCCGGGCCGGCCGCCAGGGCGATCCGGGTTCGTCGGTGTTCTTCTCCAGCTGGGAGGACGAA
CTCGTCCAGGCCCACCTCGAACCGAACAAGCGACCGATGCAGGCGGACGAGAACGGCCGGGTCCTGACCGACAAGGCGGC
CGCACTGCTCGACCACGCCCAGCGCGTGGCCGAAGGGCGTCTGCTCGACGTGCACGCCAACACCTGGCGCTACAACCAGC
TCACCGCCCAGCAGCGCGCGATCATCGTCGAGCGCCGAGATGCGTTGCTGCGCACGCCGACTGCGCGCGAGGAGCTCGCC
GAACTGTCGCCCAAGCGGTACGCCGAACTGGCCGAGGAGCTGTCCGAGGAACGGCTGGAACGGATCTGCCGGCTCATCAT
GCTCTACCACCTCGACCGTGGGTGGTGTGAGCACCTCGCCTACCTCGCCGACATCCGCGAGAGCATCCACCTGCGTGCGC
TCGGACGGCAGAACCCGCTCGACGAATTCCACCGGATGGCCGTCGACGCGTTCGCCTCACTGGCCGCCGACGCGATCGAG
GCGGCCCAGCAGACGTTCGAGACCGCACCGTCCTTCGAGGACGAACCCGGTGTGGATCTGTCCAAACTCGCGCGGCCGAC
CTCCACGTGGACCTACATGGTCCACGACAACCCGTTGGCCGACGACACGATGGCGGCGCTGAGCCTGCCGGGGGTGTTCC
GCTAG

Upstream 100 bases:

>100_bases
GCCGACCTCGCCAACCCGACGAGTAACCGGGTCTACCAGCGGTTGGGATTCGTACCGGTGGGCGATTCGATCACGGTCGA
GTTCCGCGTACCGTAAACGT

Downstream 100 bases:

>100_bases
GTTTACCGGCATGGACGCATCTGCGTCAGGGGAGCGGGACCGCGTACTGACGGTGCCCAATGCACTGTCCGTGCTGCGCC
TGGTGCTGGTTCCGGTGTTC

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 774; Mature: 773

Protein sequence:

>774_residues
MPKTTTRTPGRLSGKFWKLLGAATEKNQGRSLAQVKASADYETKAADLDDEQLRKAAELLRLEDLSESADIPQFLAIARE
AAERSTSLRPFDVQLLGALRMLAGDVVEMATGEGKTLSGAIAAAGYALGGRSVHVITINDYLARRDAEWMGPLIEALGLT
VGWITAESTAEERRRAYTCDVTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADSVLVDEALVPLVLAGTSHRET
PRVELIRMVGELTPGRDFDTDTDSRNVHLTDEGARKLEAKLGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDD
AVHLINSSRGRIAQLQRWPDGLQAAVEAKEGIATTETGEVLDTITVQALINRYPTVCGMTGTALAAGEQLRQFYKLGVSP
IEPNKPNIREDESDRVYVTAAAKIDAIIEHIEEVHKTGQPVLVGTHDVAESEELHEKLVKRGVPAVVLNAKNDAEEARVI
AEAGKLGAVTVSTQMAGRGTDIRLGGSDEGDHDEVAELGGLHVVGTGRHNTQRLDNQLRGRAGRQGDPGSSVFFSSWEDE
LVQAHLEPNKRPMQADENGRVLTDKAAALLDHAQRVAEGRLLDVHANTWRYNQLTAQQRAIIVERRDALLRTPTAREELA
ELSPKRYAELAEELSEERLERICRLIMLYHLDRGWCEHLAYLADIRESIHLRALGRQNPLDEFHRMAVDAFASLAADAIE
AAQQTFETAPSFEDEPGVDLSKLARPTSTWTYMVHDNPLADDTMAALSLPGVFR

Sequences:

>Translated_774_residues
MPKTTTRTPGRLSGKFWKLLGAATEKNQGRSLAQVKASADYETKAADLDDEQLRKAAELLRLEDLSESADIPQFLAIARE
AAERSTSLRPFDVQLLGALRMLAGDVVEMATGEGKTLSGAIAAAGYALGGRSVHVITINDYLARRDAEWMGPLIEALGLT
VGWITAESTAEERRRAYTCDVTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADSVLVDEALVPLVLAGTSHRET
PRVELIRMVGELTPGRDFDTDTDSRNVHLTDEGARKLEAKLGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDD
AVHLINSSRGRIAQLQRWPDGLQAAVEAKEGIATTETGEVLDTITVQALINRYPTVCGMTGTALAAGEQLRQFYKLGVSP
IEPNKPNIREDESDRVYVTAAAKIDAIIEHIEEVHKTGQPVLVGTHDVAESEELHEKLVKRGVPAVVLNAKNDAEEARVI
AEAGKLGAVTVSTQMAGRGTDIRLGGSDEGDHDEVAELGGLHVVGTGRHNTQRLDNQLRGRAGRQGDPGSSVFFSSWEDE
LVQAHLEPNKRPMQADENGRVLTDKAAALLDHAQRVAEGRLLDVHANTWRYNQLTAQQRAIIVERRDALLRTPTAREELA
ELSPKRYAELAEELSEERLERICRLIMLYHLDRGWCEHLAYLADIRESIHLRALGRQNPLDEFHRMAVDAFASLAADAIE
AAQQTFETAPSFEDEPGVDLSKLARPTSTWTYMVHDNPLADDTMAALSLPGVFR
>Mature_773_residues
PKTTTRTPGRLSGKFWKLLGAATEKNQGRSLAQVKASADYETKAADLDDEQLRKAAELLRLEDLSESADIPQFLAIAREA
AERSTSLRPFDVQLLGALRMLAGDVVEMATGEGKTLSGAIAAAGYALGGRSVHVITINDYLARRDAEWMGPLIEALGLTV
GWITAESTAEERRRAYTCDVTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADSVLVDEALVPLVLAGTSHRETP
RVELIRMVGELTPGRDFDTDTDSRNVHLTDEGARKLEAKLGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDDA
VHLINSSRGRIAQLQRWPDGLQAAVEAKEGIATTETGEVLDTITVQALINRYPTVCGMTGTALAAGEQLRQFYKLGVSPI
EPNKPNIREDESDRVYVTAAAKIDAIIEHIEEVHKTGQPVLVGTHDVAESEELHEKLVKRGVPAVVLNAKNDAEEARVIA
EAGKLGAVTVSTQMAGRGTDIRLGGSDEGDHDEVAELGGLHVVGTGRHNTQRLDNQLRGRAGRQGDPGSSVFFSSWEDEL
VQAHLEPNKRPMQADENGRVLTDKAAALLDHAQRVAEGRLLDVHANTWRYNQLTAQQRAIIVERRDALLRTPTAREELAE
LSPKRYAELAEELSEERLERICRLIMLYHLDRGWCEHLAYLADIRESIHLRALGRQNPLDEFHRMAVDAFASLAADAIEA
AQQTFETAPSFEDEPGVDLSKLARPTSTWTYMVHDNPLADDTMAALSLPGVFR

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=817, Percent_Identity=36.2301101591187, Blast_Score=422, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA2_MYCSJ (A3Q0I3)

Other databases:

- EMBL:   CP000580
- RefSeq:   YP_001071151.1
- ProteinModelPortal:   A3Q0I3
- SMR:   A3Q0I3
- STRING:   A3Q0I3
- EnsemblBacteria:   EBMYCT00000052108
- GeneID:   4878594
- GenomeReviews:   CP000580_GR
- KEGG:   mjl:Mjls_2881
- eggNOG:   COG0653
- GeneTree:   EBGT00050000016775
- HOGENOM:   HBG284200
- OMA:   QRVTEGQ
- ProtClustDB:   PRK12326
- BioCyc:   MSP164757:MJLS_2881-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 84855; Mature: 84724

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKTTTRTPGRLSGKFWKLLGAATEKNQGRSLAQVKASADYETKAADLDDEQLRKAAELL
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
RLEDLSESADIPQFLAIAREAAERSTSLRPFDVQLLGALRMLAGDVVEMATGEGKTLSGA
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
IAAAGYALGGRSVHVITINDYLARRDAEWMGPLIEALGLTVGWITAESTAEERRRAYTCD
HHHHHHEECCCEEEEEEECHHHHHCCHHHHHHHHHHHCCEEEEEECCHHHHHHHCEEEEE
VTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADSVLVDEALVPLVLAGTSHRET
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHEEECCCCCCC
PRVELIRMVGELTPGRDFDTDTDSRNVHLTDEGARKLEAKLGGIDLYSEEHVGTTLTEVN
HHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCEEEECCCCCCCHHHHHH
VALHAHVLLQRDVHYIVRDDAVHLINSSRGRIAQLQRWPDGLQAAVEAKEGIATTETGEV
HHHHHHHHHHHHHHHEECCCHHHHHCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCHH
LDTITVQALINRYPTVCGMTGTALAAGEQLRQFYKLGVSPIEPNKPNIREDESDRVYVTA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEE
AAKIDAIIEHIEEVHKTGQPVLVGTHDVAESEELHEKLVKRGVPAVVLNAKNDAEEARVI
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
AEAGKLGAVTVSTQMAGRGTDIRLGGSDEGDHDEVAELGGLHVVGTGRHNTQRLDNQLRG
HHCCCCCEEEEEEECCCCCCEEEECCCCCCCHHHHHHHCCEEEEECCCCHHHHHHHHHHC
RAGRQGDPGSSVFFSSWEDELVQAHLEPNKRPMQADENGRVLTDKAAALLDHAQRVAEGR
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCC
LLDVHANTWRYNQLTAQQRAIIVERRDALLRTPTAREELAELSPKRYAELAEELSEERLE
EEEEECCCEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
RICRLIMLYHLDRGWCEHLAYLADIRESIHLRALGRQNPLDEFHRMAVDAFASLAADAIE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAQQTFETAPSFEDEPGVDLSKLARPTSTWTYMVHDNPLADDTMAALSLPGVFR
HHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
PKTTTRTPGRLSGKFWKLLGAATEKNQGRSLAQVKASADYETKAADLDDEQLRKAAELL
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
RLEDLSESADIPQFLAIAREAAERSTSLRPFDVQLLGALRMLAGDVVEMATGEGKTLSGA
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
IAAAGYALGGRSVHVITINDYLARRDAEWMGPLIEALGLTVGWITAESTAEERRRAYTCD
HHHHHHEECCCEEEEEEECHHHHHCCHHHHHHHHHHHCCEEEEEECCHHHHHHHCEEEEE
VTYASVNEIGFDVLRDQLVTDVADLVSPNPDVALIDEADSVLVDEALVPLVLAGTSHRET
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHEEECCCCCCC
PRVELIRMVGELTPGRDFDTDTDSRNVHLTDEGARKLEAKLGGIDLYSEEHVGTTLTEVN
HHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCEEEECCCCCCCHHHHHH
VALHAHVLLQRDVHYIVRDDAVHLINSSRGRIAQLQRWPDGLQAAVEAKEGIATTETGEV
HHHHHHHHHHHHHHHEECCCHHHHHCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCHH
LDTITVQALINRYPTVCGMTGTALAAGEQLRQFYKLGVSPIEPNKPNIREDESDRVYVTA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEE
AAKIDAIIEHIEEVHKTGQPVLVGTHDVAESEELHEKLVKRGVPAVVLNAKNDAEEARVI
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
AEAGKLGAVTVSTQMAGRGTDIRLGGSDEGDHDEVAELGGLHVVGTGRHNTQRLDNQLRG
HHCCCCCEEEEEEECCCCCCEEEECCCCCCCHHHHHHHCCEEEEECCCCHHHHHHHHHHC
RAGRQGDPGSSVFFSSWEDELVQAHLEPNKRPMQADENGRVLTDKAAALLDHAQRVAEGR
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCC
LLDVHANTWRYNQLTAQQRAIIVERRDALLRTPTAREELAELSPKRYAELAEELSEERLE
EEEEECCCEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
RICRLIMLYHLDRGWCEHLAYLADIRESIHLRALGRQNPLDEFHRMAVDAFASLAADAIE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AAQQTFETAPSFEDEPGVDLSKLARPTSTWTYMVHDNPLADDTMAALSLPGVFR
HHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA