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The map label for this gene is fadB1 [H]

Identifier: 108799726

GI number: 108799726

Start: 2905358

End: 2906116

Strand: Reverse

Name: fadB1 [H]

Synonym: Mmcs_2760

Alternate gene names: 108799726

Gene position: 2906116-2905358 (Counterclockwise)

Preceding gene: 108799727

Following gene: 108799723

Centisome position: 50.94

GC content: 69.43

Gene sequence:

>759_bases
GTGACCCTGCAGATCAACGATGCCGACGGGGTGCGCACCGTCACGCTCGACCGGCCCGAGGCGCTCAACGCGTTCAACGA
GGCGCTCTACGACGCGACCACGGTGGCGCTGCGGGAGGCCGACGCCGATCCCGCGGTGGCCGTCGTACTGCTCACCGGAG
CCGGGCGCGCGTTCAGCGCCGGGAACGACCTCCACGAGATGGCCGCACGCGTGACCGATCCGGATTTCAAGGCGGGGGAG
TACGGCTTCCCCGGACTCATGGAGGCGCTGCTCGACCTCCGGAAACCGTTGGTGTGCGCGGTGAACGGGCTCGCGGTGGG
CATCGGGACCACGATCCTCGGCTACGCCGATCTGGTGTTCATGGCGACGACGGCGCGGTTGAAGTGTCCGTTCACCAGCC
TGGGCGTGGCACCGGAGGCGGCATCGAGCTATCTGCTGCCGCAGTTGATGGGCCGGCAGAACGCGGCGTGGATGCTGATG
TCCTCGGAATGGGTGTCGGCCGCCGAGGCGCAGCGCATGGGGATCGCCTGGCAGGTGTGCGAGCCGGACGATCTGATGGC
CGAGGCCCGCAGGCACGCCGCCGTCCTCGCCTCCCGGCCCATCCCGAGCCTGATGGCGGTCAAGGAGACCATTGTGGAGC
CGACGCGTGCCGAGGTGAAGGCCGCGCTCACCCGCGAATACGCCAAATTCGAGGTGCTCCTCGGTGGTGCGGCCAACACT
GATGCGCTGGCCGCCTTCGCGGAGCGCGGGGTGAGCTGA

Upstream 100 bases:

>100_bases
CACGGAGGCGTTCGGCGCCAACCGCGACATCGACACGGTGCCCACCAGTCGGTACGTGATGCGCAGCCCGTTCGTGGCCG
GCTGACGCTACGCTGCTGCC

Downstream 100 bases:

>100_bases
TTCCCTAGTTCGCCGGCAGCCGCGACGGGCAACCGTTGTAGTTGGCCGGGCAGCCGTTGACGTTGTGTGCCTCGATGATC
GCCCGCAGGGTGCGTCGGCA

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MTLQINDADGVRTVTLDRPEALNAFNEALYDATTVALREADADPAVAVVLLTGAGRAFSAGNDLHEMAARVTDPDFKAGE
YGFPGLMEALLDLRKPLVCAVNGLAVGIGTTILGYADLVFMATTARLKCPFTSLGVAPEAASSYLLPQLMGRQNAAWMLM
SSEWVSAAEAQRMGIAWQVCEPDDLMAEARRHAAVLASRPIPSLMAVKETIVEPTRAEVKAALTREYAKFEVLLGGAANT
DALAAFAERGVS

Sequences:

>Translated_252_residues
MTLQINDADGVRTVTLDRPEALNAFNEALYDATTVALREADADPAVAVVLLTGAGRAFSAGNDLHEMAARVTDPDFKAGE
YGFPGLMEALLDLRKPLVCAVNGLAVGIGTTILGYADLVFMATTARLKCPFTSLGVAPEAASSYLLPQLMGRQNAAWMLM
SSEWVSAAEAQRMGIAWQVCEPDDLMAEARRHAAVLASRPIPSLMAVKETIVEPTRAEVKAALTREYAKFEVLLGGAANT
DALAAFAERGVS
>Mature_251_residues
TLQINDADGVRTVTLDRPEALNAFNEALYDATTVALREADADPAVAVVLLTGAGRAFSAGNDLHEMAARVTDPDFKAGEY
GFPGLMEALLDLRKPLVCAVNGLAVGIGTTILGYADLVFMATTARLKCPFTSLGVAPEAASSYLLPQLMGRQNAAWMLMS
SEWVSAAEAQRMGIAWQVCEPDDLMAEARRHAAVLASRPIPSLMAVKETIVEPTRAEVKAALTREYAKFEVLLGGAANTD
ALAAFAERGVS

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=228, Percent_Identity=30.7017543859649, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI260275230, Length=228, Percent_Identity=30.7017543859649, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI260274832, Length=228, Percent_Identity=30.7017543859649, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI194097323, Length=201, Percent_Identity=30.3482587064677, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI221136756, Length=251, Percent_Identity=26.6932270916335, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI221136753, Length=251, Percent_Identity=26.6932270916335, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI221307494, Length=251, Percent_Identity=26.6932270916335, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4757968, Length=251, Percent_Identity=26.2948207171315, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI49355787, Length=251, Percent_Identity=26.2948207171315, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI25453481, Length=251, Percent_Identity=25.8964143426295, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI51538573, Length=251, Percent_Identity=25.8964143426295, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4757966, Length=179, Percent_Identity=29.608938547486, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI51538581, Length=179, Percent_Identity=29.608938547486, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI116235487, Length=183, Percent_Identity=27.3224043715847, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1787660, Length=229, Percent_Identity=34.4978165938865, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787659, Length=243, Percent_Identity=32.0987654320988, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI221142681, Length=210, Percent_Identity=34.7619047619048, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17549921, Length=246, Percent_Identity=32.1138211382114, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17535521, Length=222, Percent_Identity=26.5765765765766, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17554946, Length=247, Percent_Identity=27.1255060728745, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=242, Percent_Identity=27.6859504132231, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24654903, Length=220, Percent_Identity=31.3636363636364, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI20129971, Length=243, Percent_Identity=26.3374485596708, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24653477, Length=243, Percent_Identity=26.3374485596708, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24650670, Length=224, Percent_Identity=26.7857142857143, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19922422, Length=208, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 26731; Mature: 26600

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQINDADGVRTVTLDRPEALNAFNEALYDATTVALREADADPAVAVVLLTGAGRAFSA
CEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCC
GNDLHEMAARVTDPDFKAGEYGFPGLMEALLDLRKPLVCAVNGLAVGIGTTILGYADLVF
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEHHCCCHHHHHHHHHHHHHHHH
MATTARLKCPFTSLGVAPEAASSYLLPQLMGRQNAAWMLMSSEWVSAAEAQRMGIAWQVC
HHHHHHEECCHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCEEEEC
EPDDLMAEARRHAAVLASRPIPSLMAVKETIVEPTRAEVKAALTREYAKFEVLLGGAANT
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEECCCCCH
DALAAFAERGVS
HHHHHHHHHCCC
>Mature Secondary Structure 
TLQINDADGVRTVTLDRPEALNAFNEALYDATTVALREADADPAVAVVLLTGAGRAFSA
EEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCC
GNDLHEMAARVTDPDFKAGEYGFPGLMEALLDLRKPLVCAVNGLAVGIGTTILGYADLVF
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEHHCCCHHHHHHHHHHHHHHHH
MATTARLKCPFTSLGVAPEAASSYLLPQLMGRQNAAWMLMSSEWVSAAEAQRMGIAWQVC
HHHHHHEECCHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCEEEEC
EPDDLMAEARRHAAVLASRPIPSLMAVKETIVEPTRAEVKAALTREYAKFEVLLGGAANT
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEECCCCCH
DALAAFAERGVS
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]