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The map label for this gene is kstR2 [H]

Identifier: 108799515

GI number: 108799515

Start: 2708617

End: 2710065

Strand: Reverse

Name: kstR2 [H]

Synonym: Mmcs_2548

Alternate gene names: 108799515

Gene position: 2710065-2708617 (Counterclockwise)

Preceding gene: 108799517

Following gene: 108799514

Centisome position: 47.5

GC content: 64.32

Gene sequence:

>1449_bases
GTGACGGGCGACCGATGTTTCACCAGGCAGGAGGCGGTGTCCGGCCTCTCGTATCTGATACCCTTCACCAAAGATTGGGT
CAGCGGGACGAGCCCGCGTAGGGAGCCGTTGGCAGTTGGCGGAGTCGTGGAGTGTCGCACAGTGACGAACAAGCGCAATG
CAGCGAAGCGCACTTCCGACAACGGGTCCGTCGCAGGCAGCTCATATGACGACGGCACGCGCCGCACCGAGATACTGCAG
ACCGCGGCGCGCATGATCGCGACGTCGGGATTGCGCACATCACTGCAGGAGATCGCCGACGCCGCCGGCATTCTGCCCGG
CAGCCTCTATCACCACTTCGAATCCAAAGAGTCGATCCTCGTCGAACTACTGCGGCGTTATCACGCCGATCTCGACCGGA
TCGCCGAACACGCACAGGCCACGCTGGACGACCCGTCGTCACACTCCGCCTTCGACCGCGTTCTCGAGTTGAGCGTGGCA
ATCGCGCAATGTGCCGTGACGCACCGCGCCGCGCTGCAGATGTCGTTCTACGAGGGCCGCAGCTCCAACCCCGAACTGGC
GACTTTGGCGCAGCGGCGACCGACCGCGGTATTGCAGGCCATGCTGCAGACACTGCGGGCAGCCAGATGGAGCGGTTACA
TCAGGTCCGACGTCGACCTTCCGGTGCTGGCCGACCGGATGGTACAGACGATGCTGCAGGCAGGTCTCGACGTCATACGC
CAGAACACGCCCGTCGAAAAGGTGGCCACTCTGCTGACCCGAATCGAGCTCGAGGGCCTGGCAGCCGAGCCTCCGACTGA
TCAGATGCTCGACCAGTCGGCCGCGTTCTCGGCCGCCGACGCCGTCGTGCAGTCTTGGATCGACGACAGCGAGACCGAGG
CCGACGACAAGGCGGCACACGTGCGCGCAGTCGCCCGGACGGAATTCGGGCGTCGGGGTTATGAAGTCACCACCATCCGG
GACATCGCTTCGGCAGCCGGCATGGGAACCGGCACGGTGTACCGGCTGATCGGTTCCAAGGACGAGTTGCTCGTGTCGAT
CATGCGGTCCTTCGGAGAGAAGGTGGCCATGGGCTGGACCGAGGTGCTCAGTGCCGACGCGACAACGATCGAGAAGTTGG
ACGCGTTGAGCTGGATCAACACCAACGCGCTGGACCGCTTCGGTGACGAGTTTCGGATTCAGCTGGCCTGGATGAGGCAG
TCGCCTCCCGGTACACCGAACCCCGGGTGGTTGTTCTCAAAACGTGTGCGACAGATGAGAAGTCTGCTGGCCGAGGGCAT
CCGATCCGGCGAGGTGCGCGTCGACAGCCCGCCGAACGATCTGTTGGCGCGCGGCGTCATCGGCATCGGCTGGATCCCGG
AGAACATCCTGCGCGACCTCGGAACACGCCGGGCACTGATCCACGTCCGCGACACGACACTTCGTGGCGTCGTCGAACGC
AACGCCTGA

Upstream 100 bases:

>100_bases
AACAGTTTGTGGGACAAAGGTTTGGTACCAATGCAGCCTTTCACGTCCACGGCCGGCCACTCACAGCGGAACGTGTCCTA
CCAAACGGGTCTTCCACATC

Downstream 100 bases:

>100_bases
CGCCGCCCCGGCCTCCGTCACCCCCGTTTTCGAACCAAATACTTGTTCTGATGTAGCATGAGCGGAGTGCGCTCGGACGT
CGGCGGGGTGTAGCAGAGGC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MTGDRCFTRQEAVSGLSYLIPFTKDWVSGTSPRREPLAVGGVVECRTVTNKRNAAKRTSDNGSVAGSSYDDGTRRTEILQ
TAARMIATSGLRTSLQEIADAAGILPGSLYHHFESKESILVELLRRYHADLDRIAEHAQATLDDPSSHSAFDRVLELSVA
IAQCAVTHRAALQMSFYEGRSSNPELATLAQRRPTAVLQAMLQTLRAARWSGYIRSDVDLPVLADRMVQTMLQAGLDVIR
QNTPVEKVATLLTRIELEGLAAEPPTDQMLDQSAAFSAADAVVQSWIDDSETEADDKAAHVRAVARTEFGRRGYEVTTIR
DIASAAGMGTGTVYRLIGSKDELLVSIMRSFGEKVAMGWTEVLSADATTIEKLDALSWINTNALDRFGDEFRIQLAWMRQ
SPPGTPNPGWLFSKRVRQMRSLLAEGIRSGEVRVDSPPNDLLARGVIGIGWIPENILRDLGTRRALIHVRDTTLRGVVER
NA

Sequences:

>Translated_482_residues
MTGDRCFTRQEAVSGLSYLIPFTKDWVSGTSPRREPLAVGGVVECRTVTNKRNAAKRTSDNGSVAGSSYDDGTRRTEILQ
TAARMIATSGLRTSLQEIADAAGILPGSLYHHFESKESILVELLRRYHADLDRIAEHAQATLDDPSSHSAFDRVLELSVA
IAQCAVTHRAALQMSFYEGRSSNPELATLAQRRPTAVLQAMLQTLRAARWSGYIRSDVDLPVLADRMVQTMLQAGLDVIR
QNTPVEKVATLLTRIELEGLAAEPPTDQMLDQSAAFSAADAVVQSWIDDSETEADDKAAHVRAVARTEFGRRGYEVTTIR
DIASAAGMGTGTVYRLIGSKDELLVSIMRSFGEKVAMGWTEVLSADATTIEKLDALSWINTNALDRFGDEFRIQLAWMRQ
SPPGTPNPGWLFSKRVRQMRSLLAEGIRSGEVRVDSPPNDLLARGVIGIGWIPENILRDLGTRRALIHVRDTTLRGVVER
NA
>Mature_481_residues
TGDRCFTRQEAVSGLSYLIPFTKDWVSGTSPRREPLAVGGVVECRTVTNKRNAAKRTSDNGSVAGSSYDDGTRRTEILQT
AARMIATSGLRTSLQEIADAAGILPGSLYHHFESKESILVELLRRYHADLDRIAEHAQATLDDPSSHSAFDRVLELSVAI
AQCAVTHRAALQMSFYEGRSSNPELATLAQRRPTAVLQAMLQTLRAARWSGYIRSDVDLPVLADRMVQTMLQAGLDVIRQ
NTPVEKVATLLTRIELEGLAAEPPTDQMLDQSAAFSAADAVVQSWIDDSETEADDKAAHVRAVARTEFGRRGYEVTTIRD
IASAAGMGTGTVYRLIGSKDELLVSIMRSFGEKVAMGWTEVLSADATTIEKLDALSWINTNALDRFGDEFRIQLAWMRQS
PPGTPNPGWLFSKRVRQMRSLLAEGIRSGEVRVDSPPNDLLARGVIGIGWIPENILRDLGTRRALIHVRDTTLRGVVERN
A

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 52945; Mature: 52813

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDRCFTRQEAVSGLSYLIPFTKDWVSGTSPRREPLAVGGVVECRTVTNKRNAAKRTSD
CCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEECCEEEEHHHHCCHHHHHCCCC
NGSVAGSSYDDGTRRTEILQTAARMIATSGLRTSLQEIADAAGILPGSLYHHFESKESIL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHH
VELLRRYHADLDRIAEHAQATLDDPSSHSAFDRVLELSVAIAQCAVTHRAALQMSFYEGR
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SSNPELATLAQRRPTAVLQAMLQTLRAARWSGYIRSDVDLPVLADRMVQTMLQAGLDVIR
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QNTPVEKVATLLTRIELEGLAAEPPTDQMLDQSAAFSAADAVVQSWIDDSETEADDKAAH
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VRAVARTEFGRRGYEVTTIRDIASAAGMGTGTVYRLIGSKDELLVSIMRSFGEKVAMGWT
HHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EVLSADATTIEKLDALSWINTNALDRFGDEFRIQLAWMRQSPPGTPNPGWLFSKRVRQMR
HHHHCCHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
SLLAEGIRSGEVRVDSPPNDLLARGVIGIGWIPENILRDLGTRRALIHVRDTTLRGVVER
HHHHHHHCCCCEEECCCCHHHHHHCCCCCCCCCHHHHHHCCCCEEEEEEECHHHHHHHHC
NA
CC
>Mature Secondary Structure 
TGDRCFTRQEAVSGLSYLIPFTKDWVSGTSPRREPLAVGGVVECRTVTNKRNAAKRTSD
CCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEECCEEEEHHHHCCHHHHHCCCC
NGSVAGSSYDDGTRRTEILQTAARMIATSGLRTSLQEIADAAGILPGSLYHHFESKESIL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHH
VELLRRYHADLDRIAEHAQATLDDPSSHSAFDRVLELSVAIAQCAVTHRAALQMSFYEGR
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SSNPELATLAQRRPTAVLQAMLQTLRAARWSGYIRSDVDLPVLADRMVQTMLQAGLDVIR
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QNTPVEKVATLLTRIELEGLAAEPPTDQMLDQSAAFSAADAVVQSWIDDSETEADDKAAH
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VRAVARTEFGRRGYEVTTIRDIASAAGMGTGTVYRLIGSKDELLVSIMRSFGEKVAMGWT
HHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
EVLSADATTIEKLDALSWINTNALDRFGDEFRIQLAWMRQSPPGTPNPGWLFSKRVRQMR
HHHHCCHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
SLLAEGIRSGEVRVDSPPNDLLARGVIGIGWIPENILRDLGTRRALIHVRDTTLRGVVER
HHHHHHHCCCCEEECCCCHHHHHHCCCCCCCCCHHHHHHCCCCEEEEEEECHHHHHHHHC
NA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA