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The map label for this gene is rrmA [C]

Identifier: 108798837

GI number: 108798837

Start: 2014273

End: 2015052

Strand: Reverse

Name: rrmA [C]

Synonym: Mmcs_1869

Alternate gene names: 108798837

Gene position: 2015052-2014273 (Counterclockwise)

Preceding gene: 108798845

Following gene: 108798836

Centisome position: 35.32

GC content: 68.97

Gene sequence:

>780_bases
ATGAGCGCATTCGTTACCGGGCCGCGTGGGGGCGGCGACGAGACCCTCCCCCTCACCGGCGAGCGGACGATCCCCGGGCT
GGCGGAGGAGAACTACTGGTTCCGCCGCCACGAGGTCGTCTACGCCCGCCTCGCGGACCAGTGCGCCGGCCGCGACGTGC
TCGAGGCCGGATGCGGTGAGGGCTACGGGGCGGATCTGATCGCCGGGGTCGCACGACGGGTGATCGCGCTGGACTACGAC
GAGGCGACCGTCGCGCACGTGCGCGCCCGCTACCCGCGGGTGGAGATCCACCACGGCAACCTCGCCGCTTTGCCACTGGT
CGACTCGTCGGTCGACGTGGTGGTGAATTTCCAGGTGATCGAACATTTGTGGGATCAGCCACAATTCGTCGGCGAATGCC
TGCGGGTGCTGCGGCCCGGGGGGTTGCTGCTGATGTCGACCCCGAACCGGATCACCTTCTCCCCCGGCCGGGACACCCCG
GTCAACCCGTTCCACACCCGCGAACTCAACGCGGCCGAACTGACCGAATTGCTCACCACGGCCGGATTCGAGATGGAAGC
GATGCTCGGGGTCTATCACGGGCCACGCCTGCGTGAACTGGACGCCCGCCACGGCGGGTCCATCATCGACGCGCAGATCG
CCCGCGCGGTGGCCGATGCGCCGTGGCCGCAGGACCTCCTCGACGACGTCGCCGCGGTGCGCATCGACGACTTCGACCTG
ACCTCCGGAGAAGACATCGACGACAGCCTCGACCTGGTCGCGATCGCGGTGCGACCGTGA

Upstream 100 bases:

>100_bases
AACACCATAGCTGGTCGAAGTTCATGCGCCCGCCTCCCCTACCACCGTGAACCGTTCACGAACCGGCCACGACGGCGTCG
CCTGGGTTAGCCTGCCTGCG

Downstream 100 bases:

>100_bases
GCGACGACGCTCGGGTACCGGGGCTGTTCACCCTCGTCCTGCACACGCATCTGCCGTGGCTGGCGCACCACGGCCGCTGG
CCGGTCGGCGAGGAGTGGCT

Product: type 11 methyltransferase

Products: S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSAFVTGPRGGGDETLPLTGERTIPGLAEENYWFRRHEVVYARLADQCAGRDVLEAGCGEGYGADLIAGVARRVIALDYD
EATVAHVRARYPRVEIHHGNLAALPLVDSSVDVVVNFQVIEHLWDQPQFVGECLRVLRPGGLLLMSTPNRITFSPGRDTP
VNPFHTRELNAAELTELLTTAGFEMEAMLGVYHGPRLRELDARHGGSIIDAQIARAVADAPWPQDLLDDVAAVRIDDFDL
TSGEDIDDSLDLVAIAVRP

Sequences:

>Translated_259_residues
MSAFVTGPRGGGDETLPLTGERTIPGLAEENYWFRRHEVVYARLADQCAGRDVLEAGCGEGYGADLIAGVARRVIALDYD
EATVAHVRARYPRVEIHHGNLAALPLVDSSVDVVVNFQVIEHLWDQPQFVGECLRVLRPGGLLLMSTPNRITFSPGRDTP
VNPFHTRELNAAELTELLTTAGFEMEAMLGVYHGPRLRELDARHGGSIIDAQIARAVADAPWPQDLLDDVAAVRIDDFDL
TSGEDIDDSLDLVAIAVRP
>Mature_258_residues
SAFVTGPRGGGDETLPLTGERTIPGLAEENYWFRRHEVVYARLADQCAGRDVLEAGCGEGYGADLIAGVARRVIALDYDE
ATVAHVRARYPRVEIHHGNLAALPLVDSSVDVVVNFQVIEHLWDQPQFVGECLRVLRPGGLLLMSTPNRITFSPGRDTPV
NPFHTRELNAAELTELLTTAGFEMEAMLGVYHGPRLRELDARHGGSIIDAQIARAVADAPWPQDLLDDVAAVRIDDFDLT
SGEDIDDSLDLVAIAVRP

Specific function: Specifically Methylates The Guanosine In Position 745 Of 23s rRNA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR005149
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08241 Methyltransf_11; PF03551 PadR [H]

EC number: 2.1.1.51 [C]

Molecular weight: Translated: 28272; Mature: 28141

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFVTGPRGGGDETLPLTGERTIPGLAEENYWFRRHEVVYARLADQCAGRDVLEAGCGE
CCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCC
GYGADLIAGVARRVIALDYDEATVAHVRARYPRVEIHHGNLAALPLVDSSVDVVVNFQVI
CCCHHHHHHHHHHHEEECCCCHHHHHHHHHCCEEEEECCCEEEEEEECCCCEEEEEHHHH
EHLWDQPQFVGECLRVLRPGGLLLMSTPNRITFSPGRDTPVNPFHTRELNAAELTELLTT
HHHHCCHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
AGFEMEAMLGVYHGPRLRELDARHGGSIIDAQIARAVADAPWPQDLLDDVAAVRIDDFDL
CCCCHHHHHHHHCCCCHHEHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCC
TSGEDIDDSLDLVAIAVRP
CCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
SAFVTGPRGGGDETLPLTGERTIPGLAEENYWFRRHEVVYARLADQCAGRDVLEAGCGE
CCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCC
GYGADLIAGVARRVIALDYDEATVAHVRARYPRVEIHHGNLAALPLVDSSVDVVVNFQVI
CCCHHHHHHHHHHHEEECCCCHHHHHHHHHCCEEEEECCCEEEEEEECCCCEEEEEHHHH
EHLWDQPQFVGECLRVLRPGGLLLMSTPNRITFSPGRDTPVNPFHTRELNAAELTELLTT
HHHHCCHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
AGFEMEAMLGVYHGPRLRELDARHGGSIIDAQIARAVADAPWPQDLLDDVAAVRIDDFDL
CCCCHHHHHHHHCCCCHHEHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCC
TSGEDIDDSLDLVAIAVRP
CCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Unidentified protein factor B [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; rRNA [C]

Specific reaction: S-Adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

General reaction: Methyl group transfer [C]

Inhibitor: Mg2+; Unidentified protein factor A1 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155856 [H]