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The map label for this gene is cobC [C]

Identifier: 108798359

GI number: 108798359

Start: 1502209

End: 1502820

Strand: Reverse

Name: cobC [C]

Synonym: Mmcs_1388

Alternate gene names: 108798359

Gene position: 1502820-1502209 (Counterclockwise)

Preceding gene: 108798361

Following gene: 108798358

Centisome position: 26.34

GC content: 69.44

Gene sequence:

>612_bases
GTGGGCCTGACCGACCATCGACTTCTGCTCATCCGCCACGGCGAGACGGAGTGGTCGCGTTCGGGACGGCACACCAGCCG
CACCGACCTCGGGCTCACCGAAACGGGACGTGACCAGGCGACTCAGACCGCCGCGGCACTCGACCGGCTCACGCTGGACA
ACCCGCTGGTGATCAGCAGCCCGCGGCTGCGGGCACTCGACACGGCGAAACTGGCCGGGCTGGCCGTGGACGAGGTCTCC
GACCTCCTCGTGGAATGGGACTACGGCGACTACGAAGGCCGCACGACCGCCGAGATCCGCGAATCCGATCCCGAGTGGCT
GGTGTGGACCCACGGCTGCCCGGGTGGTGAGAGCGTCGAGGCGGTCAGCGAGCGCGCCGACCGTGCGGTGGAGGTCGCGC
TGGGTCACCTCGAGTCGCGTGACGTCATCTTCGTCGGGCACGGTCACTTCTCCCGGGCGGTGATCACCCGGTGGGCGGAG
TTGCCGCTGACCGACGGCATCCGGTTCGCGATGGTCGCGGCGTCGATCGCGGTGTGTGGTTGGGAGCACGGGGTGCGCCA
GATCAGCGCGTTGGCACTGACCGGTTATCCGCATCCGTGCCTGCCGACGTGA

Upstream 100 bases:

>100_bases
CCCCACCCTTTTGATTGGCGACCGCAAGTACCCGCGTCACGCGTGCCATCCTGACACGCGCACGGCCCTGACACACGGAC
GTGCGGCAGAATCGACCGGT

Downstream 100 bases:

>100_bases
CCGCCGAGCCGAGCTTCGTCCTCACCGGCGACGACGGTGTCGTACTGGCCGACGGCGTCCACACGCCGTACCCCACGCTG
GGCGACGCGTGCGCCGCGCT

Product: acid phosphatase

Products: 3-phospho-D-glycerate

Alternate protein names: Phosphoglycerate Mutase Family Protein; Alpha-Ribazole Phosphatase; Mutase; Bifunctional RNAse H/Acid Phosphatase; Acid Phosphatase; Phosphatase; Fructose-2 6-Bisphosphatase; Alpha-Ribazole-5-P Phosphatase; Phosphoglycerate Mutase Protein; Isochorismate Synthase; Alpha-Ribazole-5-Phosphate Phosphatase; Phosphoglycerate Mutase/Fructose-2 6-Bisphosphatase; Phosphoglycerate/Bisphosphoglycerate Mutase; Ribonuclease HI; Phosphoglycerate/Bisphosphoglycerate Mutase YhfR; Alpha-Ribazole Phosphatase CobC; Brocificity Phosphatase; Phosphotransferase; Phosphoglycerate Mutase Family

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MGLTDHRLLLIRHGETEWSRSGRHTSRTDLGLTETGRDQATQTAAALDRLTLDNPLVISSPRLRALDTAKLAGLAVDEVS
DLLVEWDYGDYEGRTTAEIRESDPEWLVWTHGCPGGESVEAVSERADRAVEVALGHLESRDVIFVGHGHFSRAVITRWAE
LPLTDGIRFAMVAASIAVCGWEHGVRQISALALTGYPHPCLPT

Sequences:

>Translated_203_residues
MGLTDHRLLLIRHGETEWSRSGRHTSRTDLGLTETGRDQATQTAAALDRLTLDNPLVISSPRLRALDTAKLAGLAVDEVS
DLLVEWDYGDYEGRTTAEIRESDPEWLVWTHGCPGGESVEAVSERADRAVEVALGHLESRDVIFVGHGHFSRAVITRWAE
LPLTDGIRFAMVAASIAVCGWEHGVRQISALALTGYPHPCLPT
>Mature_202_residues
GLTDHRLLLIRHGETEWSRSGRHTSRTDLGLTETGRDQATQTAAALDRLTLDNPLVISSPRLRALDTAKLAGLAVDEVSD
LLVEWDYGDYEGRTTAEIRESDPEWLVWTHGCPGGESVEAVSERADRAVEVALGHLESRDVIFVGHGHFSRAVITRWAEL
PLTDGIRFAMVAASIAVCGWEHGVRQISALALTGYPHPCLPT

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Saccharomyces cerevisiae, GI6322896, Length=185, Percent_Identity=34.0540540540541, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 5.4.2.1

Molecular weight: Translated: 22243; Mature: 22112

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLTDHRLLLIRHGETEWSRSGRHTSRTDLGLTETGRDQATQTAAALDRLTLDNPLVISS
CCCCCCEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEC
PRLRALDTAKLAGLAVDEVSDLLVEWDYGDYEGRTTAEIRESDPEWLVWTHGCPGGESVE
CCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCCEEEEECCCCCCCHHH
AVSERADRAVEVALGHLESRDVIFVGHGHFSRAVITRWAELPLTDGIRFAMVAASIAVCG
HHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
WEHGVRQISALALTGYPHPCLPT
HHHHHHHHHHEEEECCCCCCCCC
>Mature Secondary Structure 
GLTDHRLLLIRHGETEWSRSGRHTSRTDLGLTETGRDQATQTAAALDRLTLDNPLVISS
CCCCCEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEC
PRLRALDTAKLAGLAVDEVSDLLVEWDYGDYEGRTTAEIRESDPEWLVWTHGCPGGESVE
CCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCCCEEEEECCCCCCCHHH
AVSERADRAVEVALGHLESRDVIFVGHGHFSRAVITRWAELPLTDGIRFAMVAASIAVCG
HHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
WEHGVRQISALALTGYPHPCLPT
HHHHHHHHHHEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-phospho-D-glycerate

Specific reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA