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The map label for this gene is mnaA [H]

Identifier: 108798286

GI number: 108798286

Start: 1422719

End: 1423882

Strand: Direct

Name: mnaA [H]

Synonym: Mmcs_1315

Alternate gene names: 108798286

Gene position: 1422719-1423882 (Clockwise)

Preceding gene: 108798280

Following gene: 108798290

Centisome position: 24.94

GC content: 70.88

Gene sequence:

>1164_bases
GTGGGCGGCGTGACCGAAGTCCACCTGGTAGCAGGGACCCGCCCCGAGGCCATCAAGCTGGCACCGTTGGTGCCTGCCCT
GCGGGCGCAGGGCATGACGCCGGTGTTCGTGGCCAGCGGACAACATCCGACGATGGTTCATCAGGCCCTGGATGCGTTCG
GCCTCGAACCGGACGTCACGCTGAGCATCGACCGCGGCAGCGGAAGTCAGGCCGAGCTCATGGCCGCGCTGACGATGAAG
CTCGAAAAGCACTGGCAGCAGCGGACTCCCGCGGCAGTGGTGGTTCAGGGGGACACCACGACGGTGTTGGCCGCGGCGAT
GGTCGCCTTCTGGGCGAAGCTGCCGATCGCCCACCTCGAAGCGGGCCTGCGCTCACACGACCTGGCGGCGCCGTTCCCGG
AGGAGGGCAACCGCAAGCTGGTCGGCCAGATCAGCCGGCTGCATCTCGCGCCGACCGCGCGGGCGCGGGCCAACCTCGAG
CGGGAAGGCACCCCGTCGGCCGACATCGTCGTCACCGGCAACACCGTGATCGACGCGGTGCTCGGCATCGCCGCGCGAGG
CGGGCCGGTCACCGATTCCCGCGTGGCGGCGTTCGTCGAGCGGGCCCGGGCCGGCGCCAGCCGGCTGGTGCTGGTGACGG
CGCATCGTCGCGAATCCTGGGGTGAACCGCTCGACCGCGTGCTGAACGCCGTCGCGCTCTTGCTCGAGAAGTACTCCGAT
GTCGAGGTGGTGCTGCCCGCTCATCCCAATCCCGCCGTCGCAGAACAGGTCCGGGCCGTGCTCGGGGCTCATCCCCGGGT
GCTGGTGACCGAGCCCTTGGCGTATCCGGTGCTCGTCGGGGCGCTCGCGGCGTCCACGCTGGTGCTGTCGGACTCCGGAG
GTATCCAGGAGGAGGCGCCCAGCTTCGGCGTTCCGGTCATCGTCCTGCGGGAGGTCACCGAGCGGATGGAGGCCGTCGAC
GCGGGGTGCGCCATCCTCGTCGGCACCGATCGCGATGCGGTGCTGGGCAACGCCTGTCGGCTGCTCGACGATCCCGACGA
GCGGACGGCGATGGTCTCGAAGGGCAATCCGTTCGGGGACGGCCGGGCAGCGGAACGGTCCGCCGCGGCGATCGCCTGGA
TGCTCGGACGGACCGACGGGCGCCCGGCCGAATTCCGGTTCTGA

Upstream 100 bases:

>100_bases
CTGCCATTTCTGCTCGTCAACCGGGGCGGTGGCCGATGTCCGCCGAAAACAGCCTGCACTTTGCTAAGCGAATTTACAAC
ACTTCACTGAATCCGGCATA

Downstream 100 bases:

>100_bases
TCGGGGCGGCGCCGCCGTCAGGACGTGTGATCGGTGGTCAGGGAGAGGGATTCGATCGCCTCGGACACCGACTGCTGCCT
GAGCGGGACCGCGTTGAGCG

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MGGVTEVHLVAGTRPEAIKLAPLVPALRAQGMTPVFVASGQHPTMVHQALDAFGLEPDVTLSIDRGSGSQAELMAALTMK
LEKHWQQRTPAAVVVQGDTTTVLAAAMVAFWAKLPIAHLEAGLRSHDLAAPFPEEGNRKLVGQISRLHLAPTARARANLE
REGTPSADIVVTGNTVIDAVLGIAARGGPVTDSRVAAFVERARAGASRLVLVTAHRRESWGEPLDRVLNAVALLLEKYSD
VEVVLPAHPNPAVAEQVRAVLGAHPRVLVTEPLAYPVLVGALAASTLVLSDSGGIQEEAPSFGVPVIVLREVTERMEAVD
AGCAILVGTDRDAVLGNACRLLDDPDERTAMVSKGNPFGDGRAAERSAAAIAWMLGRTDGRPAEFRF

Sequences:

>Translated_387_residues
MGGVTEVHLVAGTRPEAIKLAPLVPALRAQGMTPVFVASGQHPTMVHQALDAFGLEPDVTLSIDRGSGSQAELMAALTMK
LEKHWQQRTPAAVVVQGDTTTVLAAAMVAFWAKLPIAHLEAGLRSHDLAAPFPEEGNRKLVGQISRLHLAPTARARANLE
REGTPSADIVVTGNTVIDAVLGIAARGGPVTDSRVAAFVERARAGASRLVLVTAHRRESWGEPLDRVLNAVALLLEKYSD
VEVVLPAHPNPAVAEQVRAVLGAHPRVLVTEPLAYPVLVGALAASTLVLSDSGGIQEEAPSFGVPVIVLREVTERMEAVD
AGCAILVGTDRDAVLGNACRLLDDPDERTAMVSKGNPFGDGRAAERSAAAIAWMLGRTDGRPAEFRF
>Mature_386_residues
GGVTEVHLVAGTRPEAIKLAPLVPALRAQGMTPVFVASGQHPTMVHQALDAFGLEPDVTLSIDRGSGSQAELMAALTMKL
EKHWQQRTPAAVVVQGDTTTVLAAAMVAFWAKLPIAHLEAGLRSHDLAAPFPEEGNRKLVGQISRLHLAPTARARANLER
EGTPSADIVVTGNTVIDAVLGIAARGGPVTDSRVAAFVERARAGASRLVLVTAHRRESWGEPLDRVLNAVALLLEKYSDV
EVVLPAHPNPAVAEQVRAVLGAHPRVLVTEPLAYPVLVGALAASTLVLSDSGGIQEEAPSFGVPVIVLREVTERMEAVDA
GCAILVGTDRDAVLGNACRLLDDPDERTAMVSKGNPFGDGRAAERSAAAIAWMLGRTDGRPAEFRF

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=371, Percent_Identity=41.2398921832884, Blast_Score=258, Evalue=6e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40790; Mature: 40659

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGVTEVHLVAGTRPEAIKLAPLVPALRAQGMTPVFVASGQHPTMVHQALDAFGLEPDVT
CCCCEEEEEEECCCCCCEEECCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCEE
LSIDRGSGSQAELMAALTMKLEKHWQQRTPAAVVVQGDTTTVLAAAMVAFWAKLPIAHLE
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCHHHHH
AGLRSHDLAAPFPEEGNRKLVGQISRLHLAPTARARANLEREGTPSADIVVTGNTVIDAV
CCCCCCCCCCCCCCCCCHHHHHHHHHHEECCCHHHHCCCCCCCCCCCCEEEECCHHHHHH
LGIAARGGPVTDSRVAAFVERARAGASRLVLVTAHRRESWGEPLDRVLNAVALLLEKYSD
HHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
VEVVLPAHPNPAVAEQVRAVLGAHPRVLVTEPLAYPVLVGALAASTLVLSDSGGIQEEAP
CEEEECCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHEEEEECCCCCCCCCC
SFGVPVIVLREVTERMEAVDAGCAILVGTDRDAVLGNACRLLDDPDERTAMVSKGNPFGD
CCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCHHEEEEECCCCCCC
GRAAERSAAAIAWMLGRTDGRPAEFRF
CCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
GGVTEVHLVAGTRPEAIKLAPLVPALRAQGMTPVFVASGQHPTMVHQALDAFGLEPDVT
CCCEEEEEEECCCCCCEEECCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCEE
LSIDRGSGSQAELMAALTMKLEKHWQQRTPAAVVVQGDTTTVLAAAMVAFWAKLPIAHLE
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCHHHHH
AGLRSHDLAAPFPEEGNRKLVGQISRLHLAPTARARANLEREGTPSADIVVTGNTVIDAV
CCCCCCCCCCCCCCCCCHHHHHHHHHHEECCCHHHHCCCCCCCCCCCCEEEECCHHHHHH
LGIAARGGPVTDSRVAAFVERARAGASRLVLVTAHRRESWGEPLDRVLNAVALLLEKYSD
HHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
VEVVLPAHPNPAVAEQVRAVLGAHPRVLVTEPLAYPVLVGALAASTLVLSDSGGIQEEAP
CEEEECCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHEEEEECCCCCCCCCC
SFGVPVIVLREVTERMEAVDAGCAILVGTDRDAVLGNACRLLDDPDERTAMVSKGNPFGD
CCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCHHEEEEECCCCCCC
GRAAERSAAAIAWMLGRTDGRPAEFRF
CCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]