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The map label for this gene is mshA [H]

Identifier: 108798249

GI number: 108798249

Start: 1385599

End: 1386825

Strand: Direct

Name: mshA [H]

Synonym: Mmcs_1278

Alternate gene names: 108798249

Gene position: 1385599-1386825 (Clockwise)

Preceding gene: 108798246

Following gene: 108798251

Centisome position: 24.29

GC content: 70.25

Gene sequence:

>1227_bases
ATGAAGATCGCAATGGTTTCGGAACACGCCAGCCCACTGGCGGCGCTCGGCGGGGTGGACGTCGGCGGACAGAACGTCCG
TGTGGCCGAACTGTCGGCCGCCATGGCGCGCCGTGGCCACGACGTCACCGTCTACACCCGCCGCGACGATCCGGATCTGC
CCGAACGTGTCAGCACGCCACAGGGTTACACCGTGGTGCATGTGCCCGCCGGGCCCGCGTGCCGACTGCCCGAGGACGAA
CTGCTGGTCCACACGGGTCCGTTCGCGCAGCACCTCGACCAACAGTGGAGTGCCGATCGGCCCGACGTGGCCCACGCGCA
TTTCTGGATGTCGGGCATCGCCACCCAGTTGGCCGCCCGGCATCTCGATCTGCCTGCGGTGCAGACCTTTCACGCCCTCG
GTGTGGTCGAACGCCGCCACCAGGGTTCGCACGACACCAGTCCCGAGGACCGGCTCAAGCTGGAGGCGATGGTGGCCCGC
ACCGCCACCTGGGTAGCGGCCACGTGCACCGACGAGGTGTTCGAGCTCATGCGGCTCGGCCGGTCACGCAGCCGGATCTC
GGTGGTGCCGTGCGGGGTCGACCTCGACCTCTTCACCCCGGACGGTCCGCGTGCCGAACGCGGTGCGCGGCACCGCATCG
TCAGCGTCGGAAGGCTCCTGCCCCGCAAGGGTTTCGACGTGGTCGTGCGCGCACTGACGGCGATTCCGGAGGCAGAACTC
ATCCTGGTCGGAGGACCCGAACGCAGCGAGGTGGAGGCGGACCCCGAGGCCCGCCGGCTGCGTGAGCTCGCCGAGCGGCT
CGGTGTCGGTGACCGGGTGGTCTTCCAGGGTGCCGTGGCTCGCGCGGACATGCCCGCTCTGCTGCGGTCGGCCGACGTGG
TCGCCTGTACCCCATGGTACGAACCGTTCGGCATCGTCCCGTTGGAGGCGATGGCGTCGGGTGTGCCCGTGGTGGCCGCA
GCGGTCGGCGCGATGCTCGACACCGTCGTTCAGGACGTCACCGGGCGGCTGGTCGCCGCGAGGCGCCCGGGGGAGGTCGC
CGATGCCATCAACACCCTGCTGCACGACGAATTCCTCGGACAGAGCCTCGGTGCCGCCGGACGCGACCGCGCCCGGGCCC
GATACTCGTGGGACCGCATCGCCGAAGACACCCTGCGCATCTACGACCGCCTGGTGCCCGCCGCCTCTCGGCCGCAGGCA
GCGAGGACGTCCGTTTCGTCAGTATGA

Upstream 100 bases:

>100_bases
ATCGCAGTCGGCGACGTGCATCCGCCGGCCGACCGTTCCTGCGCGATTGGAACAGGTTGATCGCCGACTGCTCCAGTCGA
CATCGCGGGAGGGGAAGCCA

Downstream 100 bases:

>100_bases
GGGCGTCAGCGGACCCGTGGGCCGAATCATGTTGGGGCAACGCTAATCCCGCGGTCCATGGCACCGTCGTCGACGGCACG
GGTCGATCTCGACTACCGAC

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKIAMVSEHASPLAALGGVDVGGQNVRVAELSAAMARRGHDVTVYTRRDDPDLPERVSTPQGYTVVHVPAGPACRLPEDE
LLVHTGPFAQHLDQQWSADRPDVAHAHFWMSGIATQLAARHLDLPAVQTFHALGVVERRHQGSHDTSPEDRLKLEAMVAR
TATWVAATCTDEVFELMRLGRSRSRISVVPCGVDLDLFTPDGPRAERGARHRIVSVGRLLPRKGFDVVVRALTAIPEAEL
ILVGGPERSEVEADPEARRLRELAERLGVGDRVVFQGAVARADMPALLRSADVVACTPWYEPFGIVPLEAMASGVPVVAA
AVGAMLDTVVQDVTGRLVAARRPGEVADAINTLLHDEFLGQSLGAAGRDRARARYSWDRIAEDTLRIYDRLVPAASRPQA
ARTSVSSV

Sequences:

>Translated_408_residues
MKIAMVSEHASPLAALGGVDVGGQNVRVAELSAAMARRGHDVTVYTRRDDPDLPERVSTPQGYTVVHVPAGPACRLPEDE
LLVHTGPFAQHLDQQWSADRPDVAHAHFWMSGIATQLAARHLDLPAVQTFHALGVVERRHQGSHDTSPEDRLKLEAMVAR
TATWVAATCTDEVFELMRLGRSRSRISVVPCGVDLDLFTPDGPRAERGARHRIVSVGRLLPRKGFDVVVRALTAIPEAEL
ILVGGPERSEVEADPEARRLRELAERLGVGDRVVFQGAVARADMPALLRSADVVACTPWYEPFGIVPLEAMASGVPVVAA
AVGAMLDTVVQDVTGRLVAARRPGEVADAINTLLHDEFLGQSLGAAGRDRARARYSWDRIAEDTLRIYDRLVPAASRPQA
ARTSVSSV
>Mature_408_residues
MKIAMVSEHASPLAALGGVDVGGQNVRVAELSAAMARRGHDVTVYTRRDDPDLPERVSTPQGYTVVHVPAGPACRLPEDE
LLVHTGPFAQHLDQQWSADRPDVAHAHFWMSGIATQLAARHLDLPAVQTFHALGVVERRHQGSHDTSPEDRLKLEAMVAR
TATWVAATCTDEVFELMRLGRSRSRISVVPCGVDLDLFTPDGPRAERGARHRIVSVGRLLPRKGFDVVVRALTAIPEAEL
ILVGGPERSEVEADPEARRLRELAERLGVGDRVVFQGAVARADMPALLRSADVVACTPWYEPFGIVPLEAMASGVPVVAA
AVGAMLDTVVQDVTGRLVAARRPGEVADAINTLLHDEFLGQSLGAAGRDRARARYSWDRIAEDTLRIYDRLVPAASRPQA
ARTSVSSV

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=411, Percent_Identity=24.5742092457421, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI14861836, Length=195, Percent_Identity=27.1794871794872, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357469, Length=212, Percent_Identity=27.8301886792453, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 44141; Mature: 44141

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAMVSEHASPLAALGGVDVGGQNVRVAELSAAMARRGHDVTVYTRRDDPDLPERVSTP
CEEEEECCCCCCHHHHCCCCCCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCCHHHCCCC
QGYTVVHVPAGPACRLPEDELLVHTGPFAQHLDQQWSADRPDVAHAHFWMSGIATQLAAR
CCEEEEEECCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
HLDLPAVQTFHALGVVERRHQGSHDTSPEDRLKLEAMVARTATWVAATCTDEVFELMRLG
HCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RSRSRISVVPCGVDLDLFTPDGPRAERGARHRIVSVGRLLPRKGFDVVVRALTAIPEAEL
CCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCE
ILVGGPERSEVEADPEARRLRELAERLGVGDRVVFQGAVARADMPALLRSADVVACTPWY
EEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHCCHHHHHHCCCEEEECCCC
EPFGIVPLEAMASGVPVVAAAVGAMLDTVVQDVTGRLVAARRPGEVADAINTLLHDEFLG
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHH
QSLGAAGRDRARARYSWDRIAEDTLRIYDRLVPAASRPQAARTSVSSV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MKIAMVSEHASPLAALGGVDVGGQNVRVAELSAAMARRGHDVTVYTRRDDPDLPERVSTP
CEEEEECCCCCCHHHHCCCCCCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCCHHHCCCC
QGYTVVHVPAGPACRLPEDELLVHTGPFAQHLDQQWSADRPDVAHAHFWMSGIATQLAAR
CCEEEEEECCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
HLDLPAVQTFHALGVVERRHQGSHDTSPEDRLKLEAMVARTATWVAATCTDEVFELMRLG
HCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RSRSRISVVPCGVDLDLFTPDGPRAERGARHRIVSVGRLLPRKGFDVVVRALTAIPEAEL
CCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCE
ILVGGPERSEVEADPEARRLRELAERLGVGDRVVFQGAVARADMPALLRSADVVACTPWY
EEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHCCHHHHHHCCCEEEECCCC
EPFGIVPLEAMASGVPVVAAAVGAMLDTVVQDVTGRLVAARRPGEVADAINTLLHDEFLG
CCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHH
QSLGAAGRDRARARYSWDRIAEDTLRIYDRLVPAASRPQAARTSVSSV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA