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The map label for this gene is groS [H]

Identifier: 108798125

GI number: 108798125

Start: 1251034

End: 1251417

Strand: Direct

Name: groS [H]

Synonym: Mmcs_1153

Alternate gene names: 108798125

Gene position: 1251034-1251417 (Clockwise)

Preceding gene: 108798124

Following gene: 108798126

Centisome position: 21.93

GC content: 62.5

Gene sequence:

>384_bases
ATGCCGATCATCTGTAAACGCTGGAAAACATTCAGGTCCGGGACCACCTGGACCTACACCGAACTAGTGGAGGGCTCCAT
CGTGGCGAGCGTGAACATCAAGCCACTCGAGGACAAGATCCTCGTCCAGGCCAACGAGGCCGAGACCACGACCGCTTCCG
GTCTGGTCATCCCGGACACCGCCAAGGAGAAGCCGCAGGAGGGCACCGTTGTCGCCGTCGGCCCCGGCCGCTGGGACGAC
GAGGGCGAAAAGCGGATCCCGCTGGACGTGTCCGAGGGCGACACCGTGATCTACAGCAAGTACGGCGGCACCGAGATCAA
GTACAACGGCGAGGAGTACCTGATCCTCTCGGCCCGCGACGTGCTGGCTGTCGTCAACAAGTAA

Upstream 100 bases:

>100_bases
CCCAGCCTTGAGTGCTAGCACTCGCATGTATAGAGTGCTAGGTGGCAGGCGGCCAACCCCTGTGTCGGCACCCGCGACGA
CGGCGCTCGGGACCGGACGC

Downstream 100 bases:

>100_bases
GCACCCGTGTCCGCCCCGGAGATCCCCGTATTGCACGGGTGATGTCCGGGGCGGCATGCGTTGCATGCCAAAAACAGGAA
GACACATATGAGCAAGCAGA

Product: chaperonin Cpn10

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MPIICKRWKTFRSGTTWTYTELVEGSIVASVNIKPLEDKILVQANEAETTTASGLVIPDTAKEKPQEGTVVAVGPGRWDD
EGEKRIPLDVSEGDTVIYSKYGGTEIKYNGEEYLILSARDVLAVVNK

Sequences:

>Translated_127_residues
MPIICKRWKTFRSGTTWTYTELVEGSIVASVNIKPLEDKILVQANEAETTTASGLVIPDTAKEKPQEGTVVAVGPGRWDD
EGEKRIPLDVSEGDTVIYSKYGGTEIKYNGEEYLILSARDVLAVVNK
>Mature_126_residues
PIICKRWKTFRSGTTWTYTELVEGSIVASVNIKPLEDKILVQANEAETTTASGLVIPDTAKEKPQEGTVVAVGPGRWDDE
GEKRIPLDVSEGDTVIYSKYGGTEIKYNGEEYLILSARDVLAVVNK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=44.7916666666667, Blast_Score=78, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=38.2978723404255, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324594, Length=97, Percent_Identity=41.2371134020619, Blast_Score=70, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358317, Length=90, Percent_Identity=41.1111111111111, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356029, Length=93, Percent_Identity=41.9354838709677, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 13961; Mature: 13830

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIICKRWKTFRSGTTWTYTELVEGSIVASVNIKPLEDKILVQANEAETTTASGLVIPDT
CCEECCCCCHHCCCCCEEEHHCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCEEECCC
AKEKPQEGTVVAVGPGRWDDEGEKRIPLDVSEGDTVIYSKYGGTEIKYNGEEYLILSARD
CCCCCCCCCEEEECCCCCCCCCCEECCEECCCCCEEEEEECCCEEEEECCCEEEEEECCC
VLAVVNK
EEEEECC
>Mature Secondary Structure 
PIICKRWKTFRSGTTWTYTELVEGSIVASVNIKPLEDKILVQANEAETTTASGLVIPDT
CEECCCCCHHCCCCCEEEHHCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCEEECCC
AKEKPQEGTVVAVGPGRWDDEGEKRIPLDVSEGDTVIYSKYGGTEIKYNGEEYLILSARD
CCCCCCCCCEEEECCCCCCCCCCEECCEECCCCCEEEEEECCCEEEEECCCEEEEEECCC
VLAVVNK
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA