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The map label for this gene is gcp [H]

Identifier: 108798123

GI number: 108798123

Start: 1249465

End: 1250487

Strand: Direct

Name: gcp [H]

Synonym: Mmcs_1151

Alternate gene names: 108798123

Gene position: 1249465-1250487 (Clockwise)

Preceding gene: 108798122

Following gene: 108798124

Centisome position: 21.9

GC content: 71.85

Gene sequence:

>1023_bases
GTGATCATCCTGGCCATCGAGAGCTCCTGCGACGAGACCGGTGTCGGCATCGCCGAACTGAGCGAAGACGGCACGGTGAC
GCTGTTGGCCGACGAGGTGGCGTCCAGCGTCGACGAGCACGCGCGCTTCGGTGGCGTGGTGCCCGAGATCGCCTCACGAG
CCCACCTCGAGGCGCTCGGCCCGACCATGCGGCGCGCGCTCGACACCGCAGGCGTCGGTAGACCCGATGTCGTCGCCGCC
ACGATCGGGCCCGGGCTGGCCGGCGCTCTGCTGGTGGGAGTGGCTGCGGCCAAGGCGTATTCGGCGGCATGGCAGGTGCC
GTTCTACGGGGTCAACCACCTCGGTGGGCACCTTGCCGCCGACGTCTACGACCACGGACCTCTGCCCGAGAGCGTCGGCC
TGCTGGTCTCCGGCGGCCACACCCACCTGCTGCACGTGCGGTCGCTGGGGGAGCCGATCATCGAACTCGGCAGCACGGTC
GACGACGCGGCGGGGGAGGCCTACGACAAGGTGGCGCGCCTGCTCGGGCTCGGCTACCCCGGCGGCAAGGTGCTCGACGA
CCTGGCCCGCCAGGGTGACCGCGAGGCGATCGTGTTCCCGCGCGGTATGACCGGCCCACGCGACGATCCGTTCGCGTTCA
GCTTCTCGGGTCTCAAGACCGCGGTCGCCCGCTACGTCGAGAGTCATCCCGAGGCGTCGCAGGCCGACGTCGCGGCGGGT
TTCCAGGAGGCGGTGGCCGACGTGCTCACCCGCAAGGCGGTGCGGGCGGCCGAGACACTCGGCGTCTCCACACTGCTCAT
CGCGGGCGGGGTGGCGGCCAACTCGCGGCTGCGGGAACTGGCCGAACAGCGGTGTGCCGAGTCCGGACTGACGCTGCGGA
TCCCGCGGCCACGGCTGTGCACCGACAACGGCGCGATGATCGCCTCGTTCGCCGCACACCTCATCGCGGCGGGCGCACCG
CCCTCACCGCTGGAGGCGGCCAGCGATCCGGGTCTGCCGGTGGTGCGGAGCCAGGTGGCGTGA

Upstream 100 bases:

>100_bases
TCACCCGGGTGGGGCTGCGCAGGCGCTACTACCGGGTCAGCGGCGCCGACGCCTATACGATGAGGCGAGACCCACCGAGC
GTTGCGAAGCGAGAAGTGCC

Downstream 100 bases:

>100_bases
ACAGAGTCGAGCAGGTCCTGGCGATCCACGAACTGCTCTACCGCTACGCCGAACTGGTCGACGCCGGGGACTTCGACGGG
GTGGGCCTGCTGCTCGCGCG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MIILAIESSCDETGVGIAELSEDGTVTLLADEVASSVDEHARFGGVVPEIASRAHLEALGPTMRRALDTAGVGRPDVVAA
TIGPGLAGALLVGVAAAKAYSAAWQVPFYGVNHLGGHLAADVYDHGPLPESVGLLVSGGHTHLLHVRSLGEPIIELGSTV
DDAAGEAYDKVARLLGLGYPGGKVLDDLARQGDREAIVFPRGMTGPRDDPFAFSFSGLKTAVARYVESHPEASQADVAAG
FQEAVADVLTRKAVRAAETLGVSTLLIAGGVAANSRLRELAEQRCAESGLTLRIPRPRLCTDNGAMIASFAAHLIAAGAP
PSPLEAASDPGLPVVRSQVA

Sequences:

>Translated_340_residues
MIILAIESSCDETGVGIAELSEDGTVTLLADEVASSVDEHARFGGVVPEIASRAHLEALGPTMRRALDTAGVGRPDVVAA
TIGPGLAGALLVGVAAAKAYSAAWQVPFYGVNHLGGHLAADVYDHGPLPESVGLLVSGGHTHLLHVRSLGEPIIELGSTV
DDAAGEAYDKVARLLGLGYPGGKVLDDLARQGDREAIVFPRGMTGPRDDPFAFSFSGLKTAVARYVESHPEASQADVAAG
FQEAVADVLTRKAVRAAETLGVSTLLIAGGVAANSRLRELAEQRCAESGLTLRIPRPRLCTDNGAMIASFAAHLIAAGAP
PSPLEAASDPGLPVVRSQVA
>Mature_340_residues
MIILAIESSCDETGVGIAELSEDGTVTLLADEVASSVDEHARFGGVVPEIASRAHLEALGPTMRRALDTAGVGRPDVVAA
TIGPGLAGALLVGVAAAKAYSAAWQVPFYGVNHLGGHLAADVYDHGPLPESVGLLVSGGHTHLLHVRSLGEPIIELGSTV
DDAAGEAYDKVARLLGLGYPGGKVLDDLARQGDREAIVFPRGMTGPRDDPFAFSFSGLKTAVARYVESHPEASQADVAAG
FQEAVADVLTRKAVRAAETLGVSTLLIAGGVAANSRLRELAEQRCAESGLTLRIPRPRLCTDNGAMIASFAAHLIAAGAP
PSPLEAASDPGLPVVRSQVA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=335, Percent_Identity=32.5373134328358, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI8923380, Length=325, Percent_Identity=31.6923076923077, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1789445, Length=327, Percent_Identity=46.7889908256881, Blast_Score=239, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI71995670, Length=323, Percent_Identity=31.5789473684211, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17557464, Length=331, Percent_Identity=29.9093655589124, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320099, Length=339, Percent_Identity=29.4985250737463, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322891, Length=345, Percent_Identity=27.2463768115942, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20129063, Length=342, Percent_Identity=31.5789473684211, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21357207, Length=335, Percent_Identity=31.3432835820896, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 34894; Mature: 34894

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILAIESSCDETGVGIAELSEDGTVTLLADEVASSVDEHARFGGVVPEIASRAHLEALG
CEEEEEECCCCCCCCCHHEECCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
PTMRRALDTAGVGRPDVVAATIGPGLAGALLVGVAAAKAYSAAWQVPFYGVNHLGGHLAA
HHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHH
DVYDHGPLPESVGLLVSGGHTHLLHVRSLGEPIIELGSTVDDAAGEAYDKVARLLGLGYP
HHHCCCCCCHHCCEEEECCCEEEEEHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
GGKVLDDLARQGDREAIVFPRGMTGPRDDPFAFSFSGLKTAVARYVESHPEASQADVAAG
CHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHH
FQEAVADVLTRKAVRAAETLGVSTLLIAGGVAANSRLRELAEQRCAESGLTLRIPRPRLC
HHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEE
TDNGAMIASFAAHLIAAGAPPSPLEAASDPGLPVVRSQVA
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MIILAIESSCDETGVGIAELSEDGTVTLLADEVASSVDEHARFGGVVPEIASRAHLEALG
CEEEEEECCCCCCCCCHHEECCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
PTMRRALDTAGVGRPDVVAATIGPGLAGALLVGVAAAKAYSAAWQVPFYGVNHLGGHLAA
HHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHH
DVYDHGPLPESVGLLVSGGHTHLLHVRSLGEPIIELGSTVDDAAGEAYDKVARLLGLGYP
HHHCCCCCCHHCCEEEECCCEEEEEHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
GGKVLDDLARQGDREAIVFPRGMTGPRDDPFAFSFSGLKTAVARYVESHPEASQADVAAG
CHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHH
FQEAVADVLTRKAVRAAETLGVSTLLIAGGVAANSRLRELAEQRCAESGLTLRIPRPRLC
HHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEE
TDNGAMIASFAAHLIAAGAPPSPLEAASDPGLPVVRSQVA
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA