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The map label for this gene is gpmA [H]

Identifier: 108797639

GI number: 108797639

Start: 720299

End: 721045

Strand: Direct

Name: gpmA [H]

Synonym: Mmcs_0659

Alternate gene names: 108797639

Gene position: 720299-721045 (Clockwise)

Preceding gene: 108797638

Following gene: 108797640

Centisome position: 12.62

GC content: 68.27

Gene sequence:

>747_bases
ATGGGAGATTCCACGCTGATCCTGCTTCGTCACGGCGAAAGTGAATGGAACGCGAAGAACCTGTTCACCGGGTGGGTCGA
CGTCGACCTGACCGACAAGGGCCGGGCCGAGGCCACGCGGGCGGGTGAGCTGATCGCCGATCTGGACCGGTTGCCCGACG
TGCTGTACACCTCGCTGCTGCGGCGCGCGATCACCACGGCCAACATCGCGTTGGACAAGGCGGACCGGCACTGGATCCCG
GTGCACCGGGACTGGCGGCTCAACGAGCGGCACTACGGGGCGCTGCAGGGGCTGAACAAGGCCGAGACCAAAGAGAAGTA
CGGCGAGGAGCAGTTCATGGCCTGGCGGCGCAGCTACGACACCCCGCCGCCGCCGATCGAGGCCGGCAGCGAGTACAGCC
AGGACCGCGATCCGCGCTACGCCGACATCGACGGCGGACCGCTCACCGAATGCCTGGCCGACGTGGTGGCCCGCTTCGTG
CCCTACTTCGAGCAGACGATCGTGCCGGATCTGCGCGAGGGCAGGACCGTGCTGATCGCCGCGCACGGCAACTCACTGCG
TGCGCTGGTCAAGTACCTCGACGGCATGTCCGACGAGGACGTGGTCGGGCTGAACATCCCGACCGGCATACCGCTGCGCT
ACGACCTGGACTCCGATCTGAAGCCGACGGTGGCAGGCGGCACGTACCTCGATCCGGAGGCCGCGGCGGCCGGCGCGGCG
GCCGTGGCATCCCAGGGCGCGAAGTAA

Upstream 100 bases:

>100_bases
CGCGCGGCGAATCGCTGAAGAATCTGCGCGCCTTCGAGCACCTCATCGACGACGACTGACGGCTCGGGTGCAACCACCGC
CCCCGTGAGAAGATTCAGCC

Downstream 100 bases:

>100_bases
GGGCCCCGAATCGAGGGGGCCAACACAAACACGCGGTGAACTGCGGCCGAACTCCTGCGATTCGCGGTGTGACTTGTCTC
GATTTGGCCGCACGCTGCTG

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MGDSTLILLRHGESEWNAKNLFTGWVDVDLTDKGRAEATRAGELIADLDRLPDVLYTSLLRRAITTANIALDKADRHWIP
VHRDWRLNERHYGALQGLNKAETKEKYGEEQFMAWRRSYDTPPPPIEAGSEYSQDRDPRYADIDGGPLTECLADVVARFV
PYFEQTIVPDLREGRTVLIAAHGNSLRALVKYLDGMSDEDVVGLNIPTGIPLRYDLDSDLKPTVAGGTYLDPEAAAAGAA
AVASQGAK

Sequences:

>Translated_248_residues
MGDSTLILLRHGESEWNAKNLFTGWVDVDLTDKGRAEATRAGELIADLDRLPDVLYTSLLRRAITTANIALDKADRHWIP
VHRDWRLNERHYGALQGLNKAETKEKYGEEQFMAWRRSYDTPPPPIEAGSEYSQDRDPRYADIDGGPLTECLADVVARFV
PYFEQTIVPDLREGRTVLIAAHGNSLRALVKYLDGMSDEDVVGLNIPTGIPLRYDLDSDLKPTVAGGTYLDPEAAAAGAA
AVASQGAK
>Mature_247_residues
GDSTLILLRHGESEWNAKNLFTGWVDVDLTDKGRAEATRAGELIADLDRLPDVLYTSLLRRAITTANIALDKADRHWIPV
HRDWRLNERHYGALQGLNKAETKEKYGEEQFMAWRRSYDTPPPPIEAGSEYSQDRDPRYADIDGGPLTECLADVVARFVP
YFEQTIVPDLREGRTVLIAAHGNSLRALVKYLDGMSDEDVVGLNIPTGIPLRYDLDSDLKPTVAGGTYLDPEAAAAGAAA
VASQGAK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=250, Percent_Identity=49.6, Blast_Score=253, Evalue=9e-68,
Organism=Homo sapiens, GI4505753, Length=250, Percent_Identity=49.6, Blast_Score=234, Evalue=5e-62,
Organism=Homo sapiens, GI4502445, Length=252, Percent_Identity=43.6507936507937, Blast_Score=223, Evalue=9e-59,
Organism=Homo sapiens, GI40353764, Length=252, Percent_Identity=43.6507936507937, Blast_Score=223, Evalue=9e-59,
Organism=Homo sapiens, GI71274132, Length=250, Percent_Identity=47.2, Blast_Score=221, Evalue=6e-58,
Organism=Homo sapiens, GI310129614, Length=165, Percent_Identity=49.6969696969697, Blast_Score=147, Evalue=8e-36,
Organism=Escherichia coli, GI1786970, Length=224, Percent_Identity=54.0178571428571, Blast_Score=254, Evalue=6e-69,
Organism=Saccharomyces cerevisiae, GI6322697, Length=245, Percent_Identity=64.0816326530612, Blast_Score=296, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6320183, Length=297, Percent_Identity=33.6700336700337, Blast_Score=163, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6324516, Length=291, Percent_Identity=32.9896907216495, Blast_Score=161, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24646216, Length=250, Percent_Identity=49.2, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=47.6, Blast_Score=227, Evalue=6e-60,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=47.6, Blast_Score=227, Evalue=6e-60,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=47.6, Blast_Score=227, Evalue=6e-60,
Organism=Drosophila melanogaster, GI28571815, Length=247, Percent_Identity=38.0566801619433, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI28571817, Length=247, Percent_Identity=38.0566801619433, Blast_Score=161, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24648979, Length=247, Percent_Identity=38.0566801619433, Blast_Score=161, Evalue=3e-40,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 27378; Mature: 27247

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDSTLILLRHGESEWNAKNLFTGWVDVDLTDKGRAEATRAGELIADLDRLPDVLYTSLL
CCCCEEEEEECCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RRAITTANIALDKADRHWIPVHRDWRLNERHYGALQGLNKAETKEKYGEEQFMAWRRSYD
HHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHCHHHHHHHHHCCC
TPPPPIEAGSEYSQDRDPRYADIDGGPLTECLADVVARFVPYFEQTIVPDLREGRTVLIA
CCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
AHGNSLRALVKYLDGMSDEDVVGLNIPTGIPLRYDLDSDLKPTVAGGTYLDPEAAAAGAA
ECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCCCCCEECCCCEECHHHHHHHHH
AVASQGAK
HHHHCCCC
>Mature Secondary Structure 
GDSTLILLRHGESEWNAKNLFTGWVDVDLTDKGRAEATRAGELIADLDRLPDVLYTSLL
CCCEEEEEECCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RRAITTANIALDKADRHWIPVHRDWRLNERHYGALQGLNKAETKEKYGEEQFMAWRRSYD
HHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHCHHHHHHHHHCCC
TPPPPIEAGSEYSQDRDPRYADIDGGPLTECLADVVARFVPYFEQTIVPDLREGRTVLIA
CCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
AHGNSLRALVKYLDGMSDEDVVGLNIPTGIPLRYDLDSDLKPTVAGGTYLDPEAAAAGAA
ECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCCCCCEECCCCEECHHHHHHHHH
AVASQGAK
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA