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The map label for this gene is uvrA [H]

Identifier: 108797583

GI number: 108797583

Start: 664541

End: 667087

Strand: Direct

Name: uvrA [H]

Synonym: Mmcs_0603

Alternate gene names: 108797583

Gene position: 664541-667087 (Clockwise)

Preceding gene: 108797580

Following gene: 108797586

Centisome position: 11.65

GC content: 70.32

Gene sequence:

>2547_bases
ATGACAGCAACTTCCGACGCGCGCGACGACGAGCACGACCCCTGCGTGCGCGTGTTCGGTACGCGGGTGCACAACCTCAA
AGGTGTCGACGTCGCCGCCCCGCGCGATGCGCTGGTCGCGTTCACCGGGATCTCGGGGTCCGGCAAGTCGTCCCTGGCGT
TCGGGACCATCTACGCCGAGGCCCAGCGACGGTACTTCGAGTCGGTCGCCCCCTACGCGCGGCGGCTCCTGTTGCCGACC
GGCGCCCCGAAGGTGGACGACATCACCGGACTGCCGCCCGCGGTGGCGCTGCAGCAGCGGCGCGGAACCGCGACGTCGCG
GTCGACGGTGGGCACCGTCACGACGCTGTCCAACCTGCTGCGGATGCTGTTCTCCCGCGCGGGCACCTACCCGCGCGGGG
CGACCGAACGCCTGGACTCCGACGCGTTCTCACCGAACACCGCGGTCGGCGCCTGTCCGGAGTGCCACGGCCTCGGCCGG
ATCCATCAGGTGACCGAGCAGACGCTGGTCCCCGACCCGTCGCTGACCATCCGCGAAGGCGCCGTCGCCGCCTGGCCGGG
GGCCTGGCAGGGGCAGAACCTGCGTGACATCCTCATCACGCTGGGCTACGACATCGACCGGCCATGGCACAAACTGCCCA
AGCGCCAACGGAATTGGATCCTGTTCACCGACGAGCAGCCGACCGTCGAGATCGATCCGAGCCAGCACCCCGTCACCGCC
GACTACTACTACAACGGGACCTTCTCGAGTGCCGAACGCCATGTCCGGCACACCCTGGCCAACTCGCAGAGCGCGACGAT
GCGCCGCCGGGTGCTGCAGTACGTCGACACCGTCGAGTGCGGGATGTGTGGCGGATCGGGGCTGCGTCCGGAGGCGCTGA
AGGTGACCTTCGCCGGCCGCACCATCGCCGACTACGTGGCGATGCCGCTGGCCGGACTCGCCGAGGCACTGCGCCCGGTC
GCCGCGCGCACCGATGCGGCGGCCGCATACGAGTCGACGGCGTCCGGTGAGTTCACCGAGGTGGCCACGATGATCGCCAC
CGACCTGGTCGCCCGCCTCCAGGTGCTCATCGATCTGGGCCTGGGCTACCTGACGCTCAACCGCCGCACCCCGACCGTGT
CGCCGGGTGAACTGCAGCGGCTCCGGTTGGCCACCCAGTTGCGCGCCGGGCTGTTCGGGGTTCTCTACGTCCTCGACGAA
CCGTCCGCGGGTCTGCATCCCGCCGATGCCGAACCCCTTCTCGAGGTGCTGGATCGCCTTCGGCGAGCGGGCAATTCGGT
ATTCGTCGTCGAGCACGACATGGACGTGGTGCGCCGTGCCGACTGGATCGTCGACGTCGGCCCCGGCGCGGGCGAACTCG
GCGGTCAGGTGCTCTACAGCGGGCCCGTCCCCGGGCTGGCCGAGATCGGTGAATCGGTAACCGGCAGATACCTTTTCGAC
TCCGCGCCCACCGCCACGCGGACGCCGCGCCCGCCGTCGGGGTGGCTGCGGATGGGCGGCATCTCGTCGCACAACCTGCG
TGACCTCGACGTCGACCTGCCACTCGGGGTCTTCGCCGCGGTCACCGGGGTGTCGGGTTCGGGCAAGTCGACGCTCGTGG
TGAAGGTGCTCGGCGACGTGGTCAACCGCCATCTGGGCCGCGCGGTGAACCAGCCGGATGCCGATGCCGCCGACGGGGAG
GATCCCGACGCCGAGATCGTCGACCTCGACCACGACGCGTCCGTCGGCGTGAGTGTGGAAGGGGTGGAGGCGATCACCCG
ACTGGTGGCCGTCGACCAGCGGCCGATCGGGCGGACCCCCCGGTCGACGCTGGCCACCTACACGGGGCTCTTCGACGCTG
TCCGGCGGGAGTTCGCCGCGACCTCCGCCGCGCGCCGACGCGGTTGGACGGCGGGCCGGTTCTCGTTCAACGTCGCCGAG
GGTCGCTGCCCGACCTGTCAGGGCGAAGGGTTCGTCTCCGTCGAATTGCTCTTTCTCCCAGGCACATACGCCACCTGTCC
GACGTGCCACGGCGCGCGTTACAACGAGGCCACACTCGGTGTCCGGTACCGCGGCCGCACGATCGCCGAGGTGCTCGCGA
TGACCGTCGACGAGGCGAGAGAGTTCTTCGCCGACATCGCCGGTGCCTCGCGCAGCCTGGCGACGTTGCACGAGGTCGGC
CTCGGCTATCTGCGTCTCGGGCAGCCTGCCACCGAACTGTCCGGCGGTGAGGCGCAACGCATCAAGCTGGCCTCGGAGCT
GCAACGGCCCAAACGCGGCCACACGCTCTACGTGCTGGACGAACCGACCACCGGTCTGCATCCGGCCGATGTCGACCTGC
TCGACGCACAGCTGCACCGCCTCGTCGACGCGGGTAACACCGTCGTGGTGGCCGAACACGACATGCGGATGGTCGCGGGA
TCCGACTGGGTCGTCGACCTCGGACCCGGCGCCGGCGCCGACGGTGGGCAGGTGGTCGCCGCGGGCACCCCGGCCGAGGT
GAGCCGGGTCGACCGCAGCCGTACCGCGCCGTATCTGGCGGCGCGCCTGGGTCACTCCACGAAGTAG

Upstream 100 bases:

>100_bases
GTCGCCCTTCGCCCGCGGCCGGGACGCCGCCACGGGGCGGGCTCGGCGACTGCAAACGCCGTGCGTGCCCGCGCGCATCG
TGGGTACCCTTCTGCGCACC

Downstream 100 bases:

>100_bases
TTGTCGTTCTCGACGAACCACTCCCGGCGCTCGTCGTCGGTGAGCTCACCGAGGTGGGCGAGGCCCTCGAAGTAGTGCTC
CCGAGGCGCACCGGGTGCGA

Product: ABC transporter-like protein

Products: NA

Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]

Number of amino acids: Translated: 848; Mature: 847

Protein sequence:

>848_residues
MTATSDARDDEHDPCVRVFGTRVHNLKGVDVAAPRDALVAFTGISGSGKSSLAFGTIYAEAQRRYFESVAPYARRLLLPT
GAPKVDDITGLPPAVALQQRRGTATSRSTVGTVTTLSNLLRMLFSRAGTYPRGATERLDSDAFSPNTAVGACPECHGLGR
IHQVTEQTLVPDPSLTIREGAVAAWPGAWQGQNLRDILITLGYDIDRPWHKLPKRQRNWILFTDEQPTVEIDPSQHPVTA
DYYYNGTFSSAERHVRHTLANSQSATMRRRVLQYVDTVECGMCGGSGLRPEALKVTFAGRTIADYVAMPLAGLAEALRPV
AARTDAAAAYESTASGEFTEVATMIATDLVARLQVLIDLGLGYLTLNRRTPTVSPGELQRLRLATQLRAGLFGVLYVLDE
PSAGLHPADAEPLLEVLDRLRRAGNSVFVVEHDMDVVRRADWIVDVGPGAGELGGQVLYSGPVPGLAEIGESVTGRYLFD
SAPTATRTPRPPSGWLRMGGISSHNLRDLDVDLPLGVFAAVTGVSGSGKSTLVVKVLGDVVNRHLGRAVNQPDADAADGE
DPDAEIVDLDHDASVGVSVEGVEAITRLVAVDQRPIGRTPRSTLATYTGLFDAVRREFAATSAARRRGWTAGRFSFNVAE
GRCPTCQGEGFVSVELLFLPGTYATCPTCHGARYNEATLGVRYRGRTIAEVLAMTVDEAREFFADIAGASRSLATLHEVG
LGYLRLGQPATELSGGEAQRIKLASELQRPKRGHTLYVLDEPTTGLHPADVDLLDAQLHRLVDAGNTVVVAEHDMRMVAG
SDWVVDLGPGAGADGGQVVAAGTPAEVSRVDRSRTAPYLAARLGHSTK

Sequences:

>Translated_848_residues
MTATSDARDDEHDPCVRVFGTRVHNLKGVDVAAPRDALVAFTGISGSGKSSLAFGTIYAEAQRRYFESVAPYARRLLLPT
GAPKVDDITGLPPAVALQQRRGTATSRSTVGTVTTLSNLLRMLFSRAGTYPRGATERLDSDAFSPNTAVGACPECHGLGR
IHQVTEQTLVPDPSLTIREGAVAAWPGAWQGQNLRDILITLGYDIDRPWHKLPKRQRNWILFTDEQPTVEIDPSQHPVTA
DYYYNGTFSSAERHVRHTLANSQSATMRRRVLQYVDTVECGMCGGSGLRPEALKVTFAGRTIADYVAMPLAGLAEALRPV
AARTDAAAAYESTASGEFTEVATMIATDLVARLQVLIDLGLGYLTLNRRTPTVSPGELQRLRLATQLRAGLFGVLYVLDE
PSAGLHPADAEPLLEVLDRLRRAGNSVFVVEHDMDVVRRADWIVDVGPGAGELGGQVLYSGPVPGLAEIGESVTGRYLFD
SAPTATRTPRPPSGWLRMGGISSHNLRDLDVDLPLGVFAAVTGVSGSGKSTLVVKVLGDVVNRHLGRAVNQPDADAADGE
DPDAEIVDLDHDASVGVSVEGVEAITRLVAVDQRPIGRTPRSTLATYTGLFDAVRREFAATSAARRRGWTAGRFSFNVAE
GRCPTCQGEGFVSVELLFLPGTYATCPTCHGARYNEATLGVRYRGRTIAEVLAMTVDEAREFFADIAGASRSLATLHEVG
LGYLRLGQPATELSGGEAQRIKLASELQRPKRGHTLYVLDEPTTGLHPADVDLLDAQLHRLVDAGNTVVVAEHDMRMVAG
SDWVVDLGPGAGADGGQVVAAGTPAEVSRVDRSRTAPYLAARLGHSTK
>Mature_847_residues
TATSDARDDEHDPCVRVFGTRVHNLKGVDVAAPRDALVAFTGISGSGKSSLAFGTIYAEAQRRYFESVAPYARRLLLPTG
APKVDDITGLPPAVALQQRRGTATSRSTVGTVTTLSNLLRMLFSRAGTYPRGATERLDSDAFSPNTAVGACPECHGLGRI
HQVTEQTLVPDPSLTIREGAVAAWPGAWQGQNLRDILITLGYDIDRPWHKLPKRQRNWILFTDEQPTVEIDPSQHPVTAD
YYYNGTFSSAERHVRHTLANSQSATMRRRVLQYVDTVECGMCGGSGLRPEALKVTFAGRTIADYVAMPLAGLAEALRPVA
ARTDAAAAYESTASGEFTEVATMIATDLVARLQVLIDLGLGYLTLNRRTPTVSPGELQRLRLATQLRAGLFGVLYVLDEP
SAGLHPADAEPLLEVLDRLRRAGNSVFVVEHDMDVVRRADWIVDVGPGAGELGGQVLYSGPVPGLAEIGESVTGRYLFDS
APTATRTPRPPSGWLRMGGISSHNLRDLDVDLPLGVFAAVTGVSGSGKSTLVVKVLGDVVNRHLGRAVNQPDADAADGED
PDAEIVDLDHDASVGVSVEGVEAITRLVAVDQRPIGRTPRSTLATYTGLFDAVRREFAATSAARRRGWTAGRFSFNVAEG
RCPTCQGEGFVSVELLFLPGTYATCPTCHGARYNEATLGVRYRGRTIAEVLAMTVDEAREFFADIAGASRSLATLHEVGL
GYLRLGQPATELSGGEAQRIKLASELQRPKRGHTLYVLDEPTTGLHPADVDLLDAQLHRLVDAGNTVVVAEHDMRMVAGS
DWVVDLGPGAGADGGQVVAAGTPAEVSRVDRSRTAPYLAARLGHSTK

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h

COG id: COG0178

COG function: function code L; Excinuclease ATPase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI2367343, Length=720, Percent_Identity=40.1388888888889, Blast_Score=509, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017871 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 90782; Mature: 90651

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATSDARDDEHDPCVRVFGTRVHNLKGVDVAAPRDALVAFTGISGSGKSSLAFGTIYAE
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEHHHHHH
AQRRYFESVAPYARRLLLPTGAPKVDDITGLPPAVALQQRRGTATSRSTVGTVTTLSNLL
HHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RMLFSRAGTYPRGATERLDSDAFSPNTAVGACPECHGLGRIHQVTEQTLVPDPSLTIREG
HHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCEEECC
AVAAWPGAWQGQNLRDILITLGYDIDRPWHKLPKRQRNWILFTDEQPTVEIDPSQHPVTA
CEEECCCCCCCCCHHHEEEECCCCCCCHHHHCCHHCCCEEEEECCCCCEEECCCCCCEEE
DYYYNGTFSSAERHVRHTLANSQSATMRRRVLQYVDTVECGMCGGSGLRPEALKVTFAGR
EEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCC
TIADYVAMPLAGLAEALRPVAARTDAAAAYESTASGEFTEVATMIATDLVARLQVLIDLG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
LGYLTLNRRTPTVSPGELQRLRLATQLRAGLFGVLYVLDEPSAGLHPADAEPLLEVLDRL
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHH
RRAGNSVFVVEHDMDVVRRADWIVDVGPGAGELGGQVLYSGPVPGLAEIGESVTGRYLFD
HHCCCEEEEEECCHHHHHHCCEEEECCCCCCCCCCEEEECCCCCCHHHHCHHHCCCEEEC
SAPTATRTPRPPSGWLRMGGISSHNLRDLDVDLPLGVFAAVTGVSGSGKSTLVVKVLGDV
CCCCCCCCCCCCCCCEEECCCCCCCCEECCCCCCHHHHHHHHCCCCCCCCEEHHHHHHHH
VNRHLGRAVNQPDADAADGEDPDAEIVDLDHDASVGVSVEGVEAITRLVAVDQRPIGRTP
HHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCC
RSTLATYTGLFDAVRREFAATSAARRRGWTAGRFSFNVAEGRCPTCQGEGFVSVELLFLP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEEEC
GTYATCPTCHGARYNEATLGVRYRGRTIAEVLAMTVDEAREFFADIAGASRSLATLHEVG
CCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
LGYLRLGQPATELSGGEAQRIKLASELQRPKRGHTLYVLDEPTTGLHPADVDLLDAQLHR
CCEEECCCCHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
LVDAGNTVVVAEHDMRMVAGSDWVVDLGPGAGADGGQVVAAGTPAEVSRVDRSRTAPYLA
HHCCCCEEEEEECCEEEEECCCEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHCCHHHH
ARLGHSTK
HHCCCCCC
>Mature Secondary Structure 
TATSDARDDEHDPCVRVFGTRVHNLKGVDVAAPRDALVAFTGISGSGKSSLAFGTIYAE
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEHHHHHH
AQRRYFESVAPYARRLLLPTGAPKVDDITGLPPAVALQQRRGTATSRSTVGTVTTLSNLL
HHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RMLFSRAGTYPRGATERLDSDAFSPNTAVGACPECHGLGRIHQVTEQTLVPDPSLTIREG
HHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCEEECC
AVAAWPGAWQGQNLRDILITLGYDIDRPWHKLPKRQRNWILFTDEQPTVEIDPSQHPVTA
CEEECCCCCCCCCHHHEEEECCCCCCCHHHHCCHHCCCEEEEECCCCCEEECCCCCCEEE
DYYYNGTFSSAERHVRHTLANSQSATMRRRVLQYVDTVECGMCGGSGLRPEALKVTFAGR
EEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCC
TIADYVAMPLAGLAEALRPVAARTDAAAAYESTASGEFTEVATMIATDLVARLQVLIDLG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
LGYLTLNRRTPTVSPGELQRLRLATQLRAGLFGVLYVLDEPSAGLHPADAEPLLEVLDRL
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHH
RRAGNSVFVVEHDMDVVRRADWIVDVGPGAGELGGQVLYSGPVPGLAEIGESVTGRYLFD
HHCCCEEEEEECCHHHHHHCCEEEECCCCCCCCCCEEEECCCCCCHHHHCHHHCCCEEEC
SAPTATRTPRPPSGWLRMGGISSHNLRDLDVDLPLGVFAAVTGVSGSGKSTLVVKVLGDV
CCCCCCCCCCCCCCCEEECCCCCCCCEECCCCCCHHHHHHHHCCCCCCCCEEHHHHHHHH
VNRHLGRAVNQPDADAADGEDPDAEIVDLDHDASVGVSVEGVEAITRLVAVDQRPIGRTP
HHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCC
RSTLATYTGLFDAVRREFAATSAARRRGWTAGRFSFNVAEGRCPTCQGEGFVSVELLFLP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEEEC
GTYATCPTCHGARYNEATLGVRYRGRTIAEVLAMTVDEAREFFADIAGASRSLATLHEVG
CCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
LGYLRLGQPATELSGGEAQRIKLASELQRPKRGHTLYVLDEPTTGLHPADVDLLDAQLHR
CCEEECCCCHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
LVDAGNTVVVAEHDMRMVAGSDWVVDLGPGAGADGGQVVAAGTPAEVSRVDRSRTAPYLA
HHCCCCEEEEEECCEEEEECCCEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHCCHHHH
ARLGHSTK
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8269961 [H]