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The map label for this gene is ftsW [H]

Identifier: 108796999

GI number: 108796999

Start: 21519

End: 22931

Strand: Reverse

Name: ftsW [H]

Synonym: Mmcs_0018

Alternate gene names: 108796999

Gene position: 22931-21519 (Counterclockwise)

Preceding gene: 108797000

Following gene: 108796998

Centisome position: 0.4

GC content: 66.81

Gene sequence:

>1413_bases
ATGACCACCCAGCCGCAGTCGCCGGTGACGGTCACTCCGCCGCTGCCGAATCGGCGCAACGCCGAACTGCTACTGCTGGC
CTTCGCCGCGGTCATCACCACCGTCGCGCTGCTGATGGTGGAGGCCAACCAGGAACAGGGCATCAGCTGGGATCTGGCCC
AGTACGCCGCCGGCTACCTGGCCCTGTTCGCCGGGGCCCACCTCGCCGTGCGCCGCTACGCGCCCTACGCCGACCCCCTG
CTCCTCCCGGTGGTCGCCCTGCTCAACGGGCTGGGCCTGGTGATGATCCACCGCCTCGACCTCGCCCAGGGCGAGCTGAC
CGGGCGGGGCCTCGGCGGCACGGCCAACCAGCAGATGCTGTGGACGCTGGTCGGCGTGATCGGATTCGCTTGTGTCATAA
CGTTTCTCAGTGATCACCGGATGCTGGCCCGCTACGGTTACGTCTGCGGGTTGACCGGTCTGGTCCTGCTCGCCATCCCG
GCTGTGCTGCCCGCCTCGATGTCGGAGCAGAACGGCGCCAAGATCTGGATCGAGTTGCCGGGCTTCTCGATTCAGCCCGC
GGAGTTCTCCAAAATCCTGCTGCTGATCTTCTTCGCCGCCGTGCTCGTCGACAAACGCGAACTGTTCACCAGTGCGGGCA
AGCACTTCCTGTGGATGGATCTCCCCCGCCCGCGCGACCTCGCCCCGCTGCTGGCGGCGTGGATCGCCTCGATCGCGGTG
ATGATCTTCGAAAAAGACCTCGGCACCTCGCTGCTGCTGTACGCGTCGTTCCTGATCCTGCTCTACGTCGCGACGGACCG
CATCAGCTGGGTGGCGATCGGCCTGAGCCTGTTCGCGGCGGGAAGCGTTGTCGCATATCACCTTTTCGGCCACGTCCGGG
TGCGGGTGCAGACCTGGCTGGACCCCTTCGCCGACCCCGAGGGTGCCGGCTACCAGATGGTGCAGTCGATGTTCAGCTTC
GCGACGGGCGGCATCTTCGGCACCGGCCTGGGCAACGGCCAGCCGGGGACGGTGCCCGCGGCGTCGACGGATTTCATCAT
CGCCGCAGTGGGGGAGGAGCTCGGCCTGGTCGGGTTCTCCGCGGTGCTGATGCTCTACACGATCCTCGTCATCCGGGGAC
TGCGCACCGCGATCGCCGTGCGTGACAGCTTCGGCAAGCTACTGGCCGCCGGTCTGGCGTCCACCCTGGCGATCCAGTTG
TTCATCGTCGTCGGCGGTGTGACGCGGCTGATCCCGCTGACGGGGCTGACCACCCCGTGGATGTCCTACGGCGGTTCCTC
ACTGCTGGCCAACTACCTGCTGTTGGCCATCCTGCTGCGCATCTCGCATGCGGCCCGCAGACCCATCAGCACCAAACCGG
TGACGCAGACACCGATCGCCGCTGCCAGCACCGAGGTGATCGACAAGGTATGA

Upstream 100 bases:

>100_bases
CCCCGACGACGGTCACCCCGCCGCCCCCTCCCCCGTCGCCCACGGTGACCGCACTGCCTCCCCCGCCACCACAACCGGGA
ACGACCTGCCGGGCGGCGTC

Downstream 100 bases:

>100_bases
ACACCTCACTGCGGCGCATCGCGGTCACGATCATGGTGCTGATCGTGCTGTTGCTCGGCAACGCCACCGTCACCCAGGTC
TTCACCGCGGATGGACTGCG

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTTQPQSPVTVTPPLPNRRNAELLLLAFAAVITTVALLMVEANQEQGISWDLAQYAAGYLALFAGAHLAVRRYAPYADPL
LLPVVALLNGLGLVMIHRLDLAQGELTGRGLGGTANQQMLWTLVGVIGFACVITFLSDHRMLARYGYVCGLTGLVLLAIP
AVLPASMSEQNGAKIWIELPGFSIQPAEFSKILLLIFFAAVLVDKRELFTSAGKHFLWMDLPRPRDLAPLLAAWIASIAV
MIFEKDLGTSLLLYASFLILLYVATDRISWVAIGLSLFAAGSVVAYHLFGHVRVRVQTWLDPFADPEGAGYQMVQSMFSF
ATGGIFGTGLGNGQPGTVPAASTDFIIAAVGEELGLVGFSAVLMLYTILVIRGLRTAIAVRDSFGKLLAAGLASTLAIQL
FIVVGGVTRLIPLTGLTTPWMSYGGSSLLANYLLLAILLRISHAARRPISTKPVTQTPIAAASTEVIDKV

Sequences:

>Translated_470_residues
MTTQPQSPVTVTPPLPNRRNAELLLLAFAAVITTVALLMVEANQEQGISWDLAQYAAGYLALFAGAHLAVRRYAPYADPL
LLPVVALLNGLGLVMIHRLDLAQGELTGRGLGGTANQQMLWTLVGVIGFACVITFLSDHRMLARYGYVCGLTGLVLLAIP
AVLPASMSEQNGAKIWIELPGFSIQPAEFSKILLLIFFAAVLVDKRELFTSAGKHFLWMDLPRPRDLAPLLAAWIASIAV
MIFEKDLGTSLLLYASFLILLYVATDRISWVAIGLSLFAAGSVVAYHLFGHVRVRVQTWLDPFADPEGAGYQMVQSMFSF
ATGGIFGTGLGNGQPGTVPAASTDFIIAAVGEELGLVGFSAVLMLYTILVIRGLRTAIAVRDSFGKLLAAGLASTLAIQL
FIVVGGVTRLIPLTGLTTPWMSYGGSSLLANYLLLAILLRISHAARRPISTKPVTQTPIAAASTEVIDKV
>Mature_469_residues
TTQPQSPVTVTPPLPNRRNAELLLLAFAAVITTVALLMVEANQEQGISWDLAQYAAGYLALFAGAHLAVRRYAPYADPLL
LPVVALLNGLGLVMIHRLDLAQGELTGRGLGGTANQQMLWTLVGVIGFACVITFLSDHRMLARYGYVCGLTGLVLLAIPA
VLPASMSEQNGAKIWIELPGFSIQPAEFSKILLLIFFAAVLVDKRELFTSAGKHFLWMDLPRPRDLAPLLAAWIASIAVM
IFEKDLGTSLLLYASFLILLYVATDRISWVAIGLSLFAAGSVVAYHLFGHVRVRVQTWLDPFADPEGAGYQMVQSMFSFA
TGGIFGTGLGNGQPGTVPAASTDFIIAAVGEELGLVGFSAVLMLYTILVIRGLRTAIAVRDSFGKLLAAGLASTLAIQLF
IVVGGVTRLIPLTGLTTPWMSYGGSSLLANYLLLAILLRISHAARRPISTKPVTQTPIAAASTEVIDKV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=322, Percent_Identity=31.9875776397516, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786853, Length=298, Percent_Identity=31.2080536912752, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 50217; Mature: 50086

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQPQSPVTVTPPLPNRRNAELLLLAFAAVITTVALLMVEANQEQGISWDLAQYAAGYL
CCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
ALFAGAHLAVRRYAPYADPLLLPVVALLNGLGLVMIHRLDLAQGELTGRGLGGTANQQML
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
WTLVGVIGFACVITFLSDHRMLARYGYVCGLTGLVLLAIPAVLPASMSEQNGAKIWIELP
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
GFSIQPAEFSKILLLIFFAAVLVDKRELFTSAGKHFLWMDLPRPRDLAPLLAAWIASIAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHH
MIFEKDLGTSLLLYASFLILLYVATDRISWVAIGLSLFAAGSVVAYHLFGHVRVRVQTWL
HHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHC
DPFADPEGAGYQMVQSMFSFATGGIFGTGLGNGQPGTVPAASTDFIIAAVGEELGLVGFS
CCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHH
AVLMLYTILVIRGLRTAIAVRDSFGKLLAAGLASTLAIQLFIVVGGVTRLIPLTGLTTPW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
MSYGGSSLLANYLLLAILLRISHAARRPISTKPVTQTPIAAASTEVIDKV
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TTQPQSPVTVTPPLPNRRNAELLLLAFAAVITTVALLMVEANQEQGISWDLAQYAAGYL
CCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
ALFAGAHLAVRRYAPYADPLLLPVVALLNGLGLVMIHRLDLAQGELTGRGLGGTANQQML
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
WTLVGVIGFACVITFLSDHRMLARYGYVCGLTGLVLLAIPAVLPASMSEQNGAKIWIELP
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
GFSIQPAEFSKILLLIFFAAVLVDKRELFTSAGKHFLWMDLPRPRDLAPLLAAWIASIAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHH
MIFEKDLGTSLLLYASFLILLYVATDRISWVAIGLSLFAAGSVVAYHLFGHVRVRVQTWL
HHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHC
DPFADPEGAGYQMVQSMFSFATGGIFGTGLGNGQPGTVPAASTDFIIAAVGEELGLVGFS
CCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHH
AVLMLYTILVIRGLRTAIAVRDSFGKLLAAGLASTLAIQLFIVVGGVTRLIPLTGLTTPW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
MSYGGSSLLANYLLLAILLRISHAARRPISTKPVTQTPIAAASTEVIDKV
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]