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The map label for this gene is trpG [H]

Identifier: 108796995

GI number: 108796995

Start: 16161

End: 16835

Strand: Direct

Name: trpG [H]

Synonym: Mmcs_0014

Alternate gene names: 108796995

Gene position: 16161-16835 (Clockwise)

Preceding gene: 108796994

Following gene: 108797003

Centisome position: 0.28

GC content: 69.48

Gene sequence:

>675_bases
ATGCAGTTCTTGGTCGTCGACAATTACGACAGCTTCGTGTTCAACCTCGTCCAGTACCTCGGACAGCTCGGGGTGGACGT
GACGGTCTGGCGCAACGACGACAGCCGGCTGAGCACCGACGCCGACATCGCCAAGGCCGCCGAGGACTTCGACGGTGTGC
TCCTCAGCCCTGGCCCGGGCACTCCCGAACGCGCAGGCGCCTCGATCCCGCTGGTGCACGCGTGCGCGGCGGCGGGCACT
CCCCTACTCGGCGTGTGCCTCGGCCATCAGGCGATCGGGGTGGCGTTCGGCGGCACCGTCGACCGCGCCCCGGAGTTGCT
GCACGGCAAGACCAGCATCGTCCACCACACCAACCGCGGTGTGCTGAAGGGACTGCCGGACCCGTTCACCGCGACCCGGT
ACCACTCGCTGACCATCCTGCCCGAAACGATGCCCGACGAGCTCGAGGTCACCGCGCGCACTCCCGGCGGCGTCATCATG
GGTGTGCGCCACGTCGACCTGCCGATCCACGGCGTGCAGTTCCACCCCGAGTCGATCCTCACCGAGGGCGGCCACCGGAT
GCTGGCCAACTGGCTGGGCTACTGCGGCAGCGCCCCGGACGAGGCGCTCGTCCGGCGCCTCGAGGACGAGGTCGCCTCGA
CGGTCGCCGCCGCTACGACGCGAAGTTCAGCGTGA

Upstream 100 bases:

>100_bases
CCGAGGTGGAACTCGTCGGCCACACCGAACCGGTCCGGATGAAGCACGCACAGCCGATCGGACCCGTCGGGTACTGACAC
ACCGGATGTAACCTGGCCGA

Downstream 100 bases:

>100_bases
TCCGGCTGTCGAAATTCACGCCGGTGCCCGGCGGCGGGGTCTGACGGACCACCGCGTTGGTGCGCTGACCGCTGTTCTGC
ACGTCGCCGCCCTTGTCGAG

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: Anthranilate synthase component II; Glutamine amido-transferase [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MQFLVVDNYDSFVFNLVQYLGQLGVDVTVWRNDDSRLSTDADIAKAAEDFDGVLLSPGPGTPERAGASIPLVHACAAAGT
PLLGVCLGHQAIGVAFGGTVDRAPELLHGKTSIVHHTNRGVLKGLPDPFTATRYHSLTILPETMPDELEVTARTPGGVIM
GVRHVDLPIHGVQFHPESILTEGGHRMLANWLGYCGSAPDEALVRRLEDEVASTVAAATTRSSA

Sequences:

>Translated_224_residues
MQFLVVDNYDSFVFNLVQYLGQLGVDVTVWRNDDSRLSTDADIAKAAEDFDGVLLSPGPGTPERAGASIPLVHACAAAGT
PLLGVCLGHQAIGVAFGGTVDRAPELLHGKTSIVHHTNRGVLKGLPDPFTATRYHSLTILPETMPDELEVTARTPGGVIM
GVRHVDLPIHGVQFHPESILTEGGHRMLANWLGYCGSAPDEALVRRLEDEVASTVAAATTRSSA
>Mature_224_residues
MQFLVVDNYDSFVFNLVQYLGQLGVDVTVWRNDDSRLSTDADIAKAAEDFDGVLLSPGPGTPERAGASIPLVHACAAAGT
PLLGVCLGHQAIGVAFGGTVDRAPELLHGKTSIVHHTNRGVLKGLPDPFTATRYHSLTILPETMPDELEVTARTPGGVIM
GVRHVDLPIHGVQFHPESILTEGGHRMLANWLGYCGSAPDEALVRRLEDEVASTVAAATTRSSA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=190, Percent_Identity=50, Blast_Score=184, Evalue=3e-48,
Organism=Escherichia coli, GI1787517, Length=194, Percent_Identity=40.2061855670103, Blast_Score=128, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI133901714, Length=173, Percent_Identity=30.635838150289, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71992717, Length=155, Percent_Identity=32.258064516129, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71992710, Length=155, Percent_Identity=32.258064516129, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=212, Percent_Identity=42.9245283018868, Blast_Score=162, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=29.8578199052133, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324878, Length=174, Percent_Identity=28.1609195402299, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 23768; Mature: 23768

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00606 B_KETOACYL_SYNTHASE ; PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFLVVDNYDSFVFNLVQYLGQLGVDVTVWRNDDSRLSTDADIAKAAEDFDGVLLSPGPG
CEEEEEECCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEECCCCC
TPERAGASIPLVHACAAAGTPLLGVCLGHQAIGVAFGGTVDRAPELLHGKTSIVHHTNRG
CHHHCCCCCHHHHHHHHCCCCHHHHHHCCHHEEEEECCCHHHCHHHHCCCHHEEEECCCC
VLKGLPDPFTATRYHSLTILPETMPDELEVTARTPGGVIMGVRHVDLPIHGVQFHPESIL
HHCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCEEEEEEEECCCEECEEECHHHHH
TEGGHRMLANWLGYCGSAPDEALVRRLEDEVASTVAAATTRSSA
HCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQFLVVDNYDSFVFNLVQYLGQLGVDVTVWRNDDSRLSTDADIAKAAEDFDGVLLSPGPG
CEEEEEECCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEECCCCC
TPERAGASIPLVHACAAAGTPLLGVCLGHQAIGVAFGGTVDRAPELLHGKTSIVHHTNRG
CHHHCCCCCHHHHHHHHCCCCHHHHHHCCHHEEEEECCCHHHCHHHHCCCHHEEEECCCC
VLKGLPDPFTATRYHSLTILPETMPDELEVTARTPGGVIMGVRHVDLPIHGVQFHPESIL
HHCCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCEEEEEEEECCCEECEEECHHHHH
TEGGHRMLANWLGYCGSAPDEALVRRLEDEVASTVAAATTRSSA
HCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]