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The map label for this gene is galU [H]

Identifier: 108763943

GI number: 108763943

Start: 1677411

End: 1678313

Strand: Direct

Name: galU [H]

Synonym: MXAN_1425

Alternate gene names: 108763943

Gene position: 1677411-1678313 (Clockwise)

Preceding gene: 108757021

Following gene: 108760063

Centisome position: 18.35

GC content: 65.45

Gene sequence:

>903_bases
ATGGCCTCCAAAACCTCGAAGGTAGAGCCCCTCATCCGCAAGTGTGTCATCCCGGCAGCCGGCCTGGGCACGCGCTTCCT
GCCGGCGACCAAGGCGGTTCCCAAGGAGATGCTGCCTATCGTCGATACTCCGACGCTCCAGTACATCGTGGAAGAGGCGG
TATCCGCCGGCATCGAGGATGTCGTCCTCATCAATGGCCGCGGCAAGGGCGCCATCGAGGACCACTTCGACATCGGCTTC
GAACTGGAGACGACGCTGCGTGCGCGCGGCAAGGATTCCGAGGCCGACAAGCTGCGCGCCATCGCGGACCTCGTGCGCGT
CGTCAGCATCCGTCAGAAGGAGCCCAAGGGACTGGGCCACGCGGTGCTGTGCGCCAAGAGCGTCATCGGCGACGAGCCCT
TCGGCGTGCTGCTGGGCGACGACATGATTGATGCCGAGGAGCCGGGAATCCGCCAGCTCGCTCGCGTGTACCGCCAGTAC
AACCAGGCGGTCATCGCGCTCATGGAAGTGCCGGAGAGTGAGACGCACATGTACGGCATCGCCGCGGGCACGGACCTGGG
TGATGGCGTCATGCGCATCGACCGCATCGTGGAGAAGCCGAAGAAGGGCACTGCGCCCTCCAACCTCGCCGTCATCGGCC
GCTACGTGCTGCCGCCCGACATCTTCCCCATCCTGGAGAACCAGACGCCGGGTGTGGGCGGCGAAATCCAGCTCACCGAC
GGCCTGGCCACGCTCCAGCAGTCGAAGGGGCTGCTCGGCTACCGCTTCAAGGGTCAGCGCTATGACGCGGGCGACAAGGT
GGGGTACCTGAAGGCCAACATCGCCTACGCGCTCAAGCGTCCGGACCTGCGTGCCGGGCTGCTCGAGTACATGCGTGAAG
TCGTGAAGACGGAGAAGCCGTGA

Upstream 100 bases:

>100_bases
ACACACAAAGGGCAATCAGCACCAAGGCGCGGAGCAACATGACAAGTCCATCCTATCCAGCTTGATGGGGTCAGGGGCCA
TCAATAGATTCCCAGCCCTC

Downstream 100 bases:

>100_bases
AGCGCACCGTTGCACTCCTCGCTGTCCTGGTCTCCTTCGCCGCGGCGGCCTACGTGCTGCCCGGCAGCTCCATCATCCGC
CGCATGTCGGCGGAGCGCGC

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MASKTSKVEPLIRKCVIPAAGLGTRFLPATKAVPKEMLPIVDTPTLQYIVEEAVSAGIEDVVLINGRGKGAIEDHFDIGF
ELETTLRARGKDSEADKLRAIADLVRVVSIRQKEPKGLGHAVLCAKSVIGDEPFGVLLGDDMIDAEEPGIRQLARVYRQY
NQAVIALMEVPESETHMYGIAAGTDLGDGVMRIDRIVEKPKKGTAPSNLAVIGRYVLPPDIFPILENQTPGVGGEIQLTD
GLATLQQSKGLLGYRFKGQRYDAGDKVGYLKANIAYALKRPDLRAGLLEYMREVVKTEKP

Sequences:

>Translated_300_residues
MASKTSKVEPLIRKCVIPAAGLGTRFLPATKAVPKEMLPIVDTPTLQYIVEEAVSAGIEDVVLINGRGKGAIEDHFDIGF
ELETTLRARGKDSEADKLRAIADLVRVVSIRQKEPKGLGHAVLCAKSVIGDEPFGVLLGDDMIDAEEPGIRQLARVYRQY
NQAVIALMEVPESETHMYGIAAGTDLGDGVMRIDRIVEKPKKGTAPSNLAVIGRYVLPPDIFPILENQTPGVGGEIQLTD
GLATLQQSKGLLGYRFKGQRYDAGDKVGYLKANIAYALKRPDLRAGLLEYMREVVKTEKP
>Mature_299_residues
ASKTSKVEPLIRKCVIPAAGLGTRFLPATKAVPKEMLPIVDTPTLQYIVEEAVSAGIEDVVLINGRGKGAIEDHFDIGFE
LETTLRARGKDSEADKLRAIADLVRVVSIRQKEPKGLGHAVLCAKSVIGDEPFGVLLGDDMIDAEEPGIRQLARVYRQYN
QAVIALMEVPESETHMYGIAAGTDLGDGVMRIDRIVEKPKKGTAPSNLAVIGRYVLPPDIFPILENQTPGVGGEIQLTDG
LATLQQSKGLLGYRFKGQRYDAGDKVGYLKANIAYALKRPDLRAGLLEYMREVVKTEKP

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=300, Percent_Identity=43, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1788355, Length=276, Percent_Identity=42.0289855072464, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1790224, Length=230, Percent_Identity=26.0869565217391, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32619; Mature: 32488

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKTSKVEPLIRKCVIPAAGLGTRFLPATKAVPKEMLPIVDTPTLQYIVEEAVSAGIED
CCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHCCCCCCHHHHHHHHHHHHCCCCE
VVLINGRGKGAIEDHFDIGFELETTLRARGKDSEADKLRAIADLVRVVSIRQKEPKGLGH
EEEECCCCCCCCCCCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
AVLCAKSVIGDEPFGVLLGDDMIDAEEPGIRQLARVYRQYNQAVIALMEVPESETHMYGI
HHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
AAGTDLGDGVMRIDRIVEKPKKGTAPSNLAVIGRYVLPPDIFPILENQTPGVGGEIQLTD
EECCCCCHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCCCHHHHHCCCCCCCCCEEEECC
GLATLQQSKGLLGYRFKGQRYDAGDKVGYLKANIAYALKRPDLRAGLLEYMREVVKTEKP
HHHHHHHCCCCEEEEECCCCCCCCCCEEEEEHHEEEEECCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASKTSKVEPLIRKCVIPAAGLGTRFLPATKAVPKEMLPIVDTPTLQYIVEEAVSAGIED
CCCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHCCCCCCHHHHHHHHHHHHCCCCE
VVLINGRGKGAIEDHFDIGFELETTLRARGKDSEADKLRAIADLVRVVSIRQKEPKGLGH
EEEECCCCCCCCCCCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCH
AVLCAKSVIGDEPFGVLLGDDMIDAEEPGIRQLARVYRQYNQAVIALMEVPESETHMYGI
HHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
AAGTDLGDGVMRIDRIVEKPKKGTAPSNLAVIGRYVLPPDIFPILENQTPGVGGEIQLTD
EECCCCCHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCCCHHHHHCCCCCCCCCEEEECC
GLATLQQSKGLLGYRFKGQRYDAGDKVGYLKANIAYALKRPDLRAGLLEYMREVVKTEKP
HHHHHHHCCCCEEEEECCCCCCCCCCEEEEEHHEEEEECCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]