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The map label for this gene is cusB [H]

Identifier: 108763876

GI number: 108763876

Start: 1144331

End: 1145512

Strand: Reverse

Name: cusB [H]

Synonym: MXAN_0989

Alternate gene names: 108763876

Gene position: 1145512-1144331 (Counterclockwise)

Preceding gene: 108762262

Following gene: 108762817

Centisome position: 12.53

GC content: 69.8

Gene sequence:

>1182_bases
ATGGGCCGGCGCATGCTGGCGTGTGGCACCACCAGCGAGTGGCGCTCGGCCGCTCCCGCGGGTGCTCACGGCGAGGGCGA
TATCGCGCACTACACCTGCCCCATGCACCCGTCCGTGAAGCAGCACGGCCCGGGCGCGTGCCCCATCTGCGGCATGGACC
TGACACCCGTCAGCCGCGCCGAGCTGCAGAGCGGCATCATCCGGGTGGACGACCTGCGGCGGCAGCGCATCGGCGTGAAG
ACGGCGAAGGTGGAGCAGTCCTCCATGGACCTGTCCCTGCGCGCGCTCGGCCGCGTCACCTTCGACGAGAAGTCACTGGT
GGACGTCACCCTCAAGCTGGACGGCTACATCCACGAGCTGCGCGTCAACGCCACGGGCGAGCCGGTGAAGAAGGGCGACG
TCCTCTTCACCCTCTACAGCCCGGAGCTCTACGCCGCGCAGCAGGAGTACCTGCTGGCGCGTCAGAGCCAGAGCGCGGCC
AACGCGTCGCTCGTGGGCGCGGCGCGCAAGCGGCTGGAACTATGGGGCCTGTCCGCGGCGCAAATCGAGCGCGTCGCCCA
GCGTGGCCAGCCGGTGGAGAACATGCCCTTCCTGGCGCCCGCCAGCGGCTACGTGCTGGAGAAGAACGTGGTGGAGGGCG
CGGCGGTGAAGGCCGGTGAGCGCCTGTTCCGCATCGCCCCGCTGGCGAAGGTGTGGGTGGAAGCGGATGTGTACGAGCAG
GACCTGGCGCGCGTGAAGCCGGGCCATCCAGTGGAAGTCACCCTGCCCTACCTGCCTGGGAAGAAATACGCGGGCAGCGT
CGGCTACGTGTACCCGTCCCTACAAGGCGCCACGCGCACCGGGCGCATCCGCATCGAGCTGCCCAACCCGGAGCTGGAGC
TGAAGCCGGACATGTACGCGGACGTCCGCTTCCTCCTGCAGGGCGGCGCGCCGCGACTCCAGATTCCCGACTCGGCCGTC
ATCTACACCGGCCCGCGGCGGCTGGTGTTCGTGGACCTGGGCGAGGGACGGCTGCGGCCCCAGGAGGTGAAGCTCGGCAT
CAAGGGCAACGGCACCTACGAGGTGCTGGAGGGCCTGTCGCCCGGCGACGTCGTCGTCACCAGCGGCAACTTCCTCATCG
CGGCGGAGAGCCGCATCCGCTCCGCCACGGATGACTTCGGAGGCAGCCATGCAGCCCACTGA

Upstream 100 bases:

>100_bases
CGATCCGCGGCTCCAGGAAGGCTGGCACGTCTTCGAATGCCCCATGGTGGAGGGGGTGAATCAGTGGCTCCAGCGCGAGC
CCAAGCTGGAGAACCCGTAC

Downstream 100 bases:

>100_bases
GAACGGCGAACAGGGCTTCATCGGCCGCATCATCGGCGCGTGCGCGCGCAACCCGTTCCTCACCATCCTGCTGGTGGGCG
GCCTGGCGGCGTGGGCCGTC

Product: cation efflux system protein CusB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MGRRMLACGTTSEWRSAAPAGAHGEGDIAHYTCPMHPSVKQHGPGACPICGMDLTPVSRAELQSGIIRVDDLRRQRIGVK
TAKVEQSSMDLSLRALGRVTFDEKSLVDVTLKLDGYIHELRVNATGEPVKKGDVLFTLYSPELYAAQQEYLLARQSQSAA
NASLVGAARKRLELWGLSAAQIERVAQRGQPVENMPFLAPASGYVLEKNVVEGAAVKAGERLFRIAPLAKVWVEADVYEQ
DLARVKPGHPVEVTLPYLPGKKYAGSVGYVYPSLQGATRTGRIRIELPNPELELKPDMYADVRFLLQGGAPRLQIPDSAV
IYTGPRRLVFVDLGEGRLRPQEVKLGIKGNGTYEVLEGLSPGDVVVTSGNFLIAAESRIRSATDDFGGSHAAH

Sequences:

>Translated_393_residues
MGRRMLACGTTSEWRSAAPAGAHGEGDIAHYTCPMHPSVKQHGPGACPICGMDLTPVSRAELQSGIIRVDDLRRQRIGVK
TAKVEQSSMDLSLRALGRVTFDEKSLVDVTLKLDGYIHELRVNATGEPVKKGDVLFTLYSPELYAAQQEYLLARQSQSAA
NASLVGAARKRLELWGLSAAQIERVAQRGQPVENMPFLAPASGYVLEKNVVEGAAVKAGERLFRIAPLAKVWVEADVYEQ
DLARVKPGHPVEVTLPYLPGKKYAGSVGYVYPSLQGATRTGRIRIELPNPELELKPDMYADVRFLLQGGAPRLQIPDSAV
IYTGPRRLVFVDLGEGRLRPQEVKLGIKGNGTYEVLEGLSPGDVVVTSGNFLIAAESRIRSATDDFGGSHAAH
>Mature_392_residues
GRRMLACGTTSEWRSAAPAGAHGEGDIAHYTCPMHPSVKQHGPGACPICGMDLTPVSRAELQSGIIRVDDLRRQRIGVKT
AKVEQSSMDLSLRALGRVTFDEKSLVDVTLKLDGYIHELRVNATGEPVKKGDVLFTLYSPELYAAQQEYLLARQSQSAAN
ASLVGAARKRLELWGLSAAQIERVAQRGQPVENMPFLAPASGYVLEKNVVEGAAVKAGERLFRIAPLAKVWVEADVYEQD
LARVKPGHPVEVTLPYLPGKKYAGSVGYVYPSLQGATRTGRIRIELPNPELELKPDMYADVRFLLQGGAPRLQIPDSAVI
YTGPRRLVFVDLGEGRLRPQEVKLGIKGNGTYEVLEGLSPGDVVVTSGNFLIAAESRIRSATDDFGGSHAAH

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=390, Percent_Identity=29.2307692307692, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87081796, Length=319, Percent_Identity=28.2131661442006, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 42603; Mature: 42472

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRRMLACGTTSEWRSAAPAGAHGEGDIAHYTCPMHPSVKQHGPGACPICGMDLTPVSRA
CCCEEEEECCCHHHHHCCCCCCCCCCCEEEEECCCCCCHHHCCCCCCCEECCCCCCCCHH
ELQSGIIRVDDLRRQRIGVKTAKVEQSSMDLSLRALGRVTFDEKSLVDVTLKLDGYIHEL
HHHCCCEEEHHHHHHHCCCEEEEECCCCCCEEEEEHEEEEECCCCEEEEEEEECCEEEEE
RVNATGEPVKKGDVLFTLYSPELYAAQQEYLLARQSQSAANASLVGAARKRLELWGLSAA
EECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHH
QIERVAQRGQPVENMPFLAPASGYVLEKNVVEGAAVKAGERLFRIAPLAKVWVEADVYEQ
HHHHHHHCCCCCCCCCEECCCCCCEEECCCCCCHHHHHCHHHEECCCHHHHHEECHHHHH
DLARVKPGHPVEVTLPYLPGKKYAGSVGYVYPSLQGATRTGRIRIELPNPELELKPDMYA
HHHHCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCEEECCCHHH
DVRFLLQGGAPRLQIPDSAVIYTGPRRLVFVDLGEGRLRPQEVKLGIKGNGTYEVLEGLS
HHHHHHCCCCCEEECCCCEEEEECCCEEEEEECCCCCCCHHHEEEEECCCCHHHHHCCCC
PGDVVVTSGNFLIAAESRIRSATDDFGGSHAAH
CCCEEEECCCEEEEECHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
GRRMLACGTTSEWRSAAPAGAHGEGDIAHYTCPMHPSVKQHGPGACPICGMDLTPVSRA
CCEEEEECCCHHHHHCCCCCCCCCCCEEEEECCCCCCHHHCCCCCCCEECCCCCCCCHH
ELQSGIIRVDDLRRQRIGVKTAKVEQSSMDLSLRALGRVTFDEKSLVDVTLKLDGYIHEL
HHHCCCEEEHHHHHHHCCCEEEEECCCCCCEEEEEHEEEEECCCCEEEEEEEECCEEEEE
RVNATGEPVKKGDVLFTLYSPELYAAQQEYLLARQSQSAANASLVGAARKRLELWGLSAA
EECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHH
QIERVAQRGQPVENMPFLAPASGYVLEKNVVEGAAVKAGERLFRIAPLAKVWVEADVYEQ
HHHHHHHCCCCCCCCCEECCCCCCEEECCCCCCHHHHHCHHHEECCCHHHHHEECHHHHH
DLARVKPGHPVEVTLPYLPGKKYAGSVGYVYPSLQGATRTGRIRIELPNPELELKPDMYA
HHHHCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCEEECCCHHH
DVRFLLQGGAPRLQIPDSAVIYTGPRRLVFVDLGEGRLRPQEVKLGIKGNGTYEVLEGLS
HHHHHHCCCCCEEECCCCEEEEECCCEEEEEECCCCCCCHHHEEEEECCCCHHHHHCCCC
PGDVVVTSGNFLIAAESRIRSATDDFGGSHAAH
CCCEEEECCCEEEEECHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]