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The map label for this gene is coaX

Identifier: 108763851

GI number: 108763851

Start: 5099219

End: 5099989

Strand: Reverse

Name: coaX

Synonym: MXAN_4151

Alternate gene names: 108763851

Gene position: 5099989-5099219 (Counterclockwise)

Preceding gene: 108763373

Following gene: 108757001

Centisome position: 55.8

GC content: 66.41

Gene sequence:

>771_bases
ATGCTCCTGGCCATCGACGTCGGCAACACCAATACCGTGCTCGGAGTGTTCGAGGGCCGGCGCCTGCTCGACCACTGGCG
CGTAGAGACCAGCACGCGCCGCACCTCGGATGAGTACGGCATCCTGGTCCGGCAGCTCTTCACCCATCGCGGCATCGACC
CGATGAAGGTGACCGCGGTCGTCGTCTCCAGCGTGGTGCCGCCGCTCCAGTCCAACCTGGAGAAGATGAGCGAGCGGTAC
TTCCGCGTCCGTCCCATGTTCATCGGGCCCGGCGTGAAGACGGGCATGCCCATCCTCTACGACAACCCCCGGGAGGTGGG
CGCGGACCGCATCGTCAACGCGGTGTCCGCCTACGAGAGACACCACGCCGGCGTGTTGGTCGTGGACTTCGGCACCGCGA
CGACGTTCGACGCGGTGTCGCCGAAGGGGGAGTACCTGGGGGGCTGCATCTGCCCCGGCATCAACATCTCCATGGAGGCG
CTGTTCCAGAATGCCTCCAAGTTGCCGCGCGTGGAGTTCGCGCGGCCGCCGCATGTCATCGGGCGCAACACCGTGCACTC
CATGCAGGCCGGGCTCGTCTACGGCTACGTGGGCATGGTGGACGGCATCTGCGCCCGCATGCAGGCCGAACTGGGCTTTC
CGGTGAAGGTCGTCGCCACCGGAGGGCTCGCGTCGCTGGTGGCCAGCGAGTCCAAGGCCATCCACCAGGTGGATGAGTTC
CTCACGCTCGAGGGCCTGCGCATCATCTACGGAAGGAATCACGCGTCATGA

Upstream 100 bases:

>100_bases
TCCGGGGCGCTGCTGGTCCGGACGGCGGAGGGCTCGCTCGAACGTGTGTTGGCGGGCGACGTGGAGCAGCTGCGCCCACG
GCGGTAGAGTGCGCGGTGTC

Downstream 100 bases:

>100_bases
CCACTGCCGCTCCCAACGCCGTCCCGGCGCCGCCTCCGGGCTGTCCCTTCGATGCGGAGTTCCTGCCGCCCAACCTGCGC
AAGCACGTGGACCCCGCGGC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MLLAIDVGNTNTVLGVFEGRRLLDHWRVETSTRRTSDEYGILVRQLFTHRGIDPMKVTAVVVSSVVPPLQSNLEKMSERY
FRVRPMFIGPGVKTGMPILYDNPREVGADRIVNAVSAYERHHAGVLVVDFGTATTFDAVSPKGEYLGGCICPGINISMEA
LFQNASKLPRVEFARPPHVIGRNTVHSMQAGLVYGYVGMVDGICARMQAELGFPVKVVATGGLASLVASESKAIHQVDEF
LTLEGLRIIYGRNHAS

Sequences:

>Translated_256_residues
MLLAIDVGNTNTVLGVFEGRRLLDHWRVETSTRRTSDEYGILVRQLFTHRGIDPMKVTAVVVSSVVPPLQSNLEKMSERY
FRVRPMFIGPGVKTGMPILYDNPREVGADRIVNAVSAYERHHAGVLVVDFGTATTFDAVSPKGEYLGGCICPGINISMEA
LFQNASKLPRVEFARPPHVIGRNTVHSMQAGLVYGYVGMVDGICARMQAELGFPVKVVATGGLASLVASESKAIHQVDEF
LTLEGLRIIYGRNHAS
>Mature_256_residues
MLLAIDVGNTNTVLGVFEGRRLLDHWRVETSTRRTSDEYGILVRQLFTHRGIDPMKVTAVVVSSVVPPLQSNLEKMSERY
FRVRPMFIGPGVKTGMPILYDNPREVGADRIVNAVSAYERHHAGVLVVDFGTATTFDAVSPKGEYLGGCICPGINISMEA
LFQNASKLPRVEFARPPHVIGRNTVHSMQAGLVYGYVGMVDGICARMQAELGFPVKVVATGGLASLVASESKAIHQVDEF
LTLEGLRIIYGRNHAS

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_MYXXD (Q1D4U7)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_632326.1
- ProteinModelPortal:   Q1D4U7
- SMR:   Q1D4U7
- STRING:   Q1D4U7
- GeneID:   4107612
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_4151
- TIGR:   MXAN_4151
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13321
- BioCyc:   MXAN246197:MXAN_4151-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27983; Mature: 27983

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 100-100 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAIDVGNTNTVLGVFEGRRLLDHWRVETSTRRTSDEYGILVRQLFTHRGIDPMKVTAV
CEEEEEECCCCEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
VVSSVVPPLQSNLEKMSERYFRVRPMFIGPGVKTGMPILYDNPREVGADRIVNAVSAYER
HHHHHCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
HHAGVLVVDFGTATTFDAVSPKGEYLGGCICPGINISMEALFQNASKLPRVEFARPPHVI
HCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GRNTVHSMQAGLVYGYVGMVDGICARMQAELGFPVKVVATGGLASLVASESKAIHQVDEF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
LTLEGLRIIYGRNHAS
HHHCCEEEEECCCCCC
>Mature Secondary Structure
MLLAIDVGNTNTVLGVFEGRRLLDHWRVETSTRRTSDEYGILVRQLFTHRGIDPMKVTAV
CEEEEEECCCCEEEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
VVSSVVPPLQSNLEKMSERYFRVRPMFIGPGVKTGMPILYDNPREVGADRIVNAVSAYER
HHHHHCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
HHAGVLVVDFGTATTFDAVSPKGEYLGGCICPGINISMEALFQNASKLPRVEFARPPHVI
HCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GRNTVHSMQAGLVYGYVGMVDGICARMQAELGFPVKVVATGGLASLVASESKAIHQVDEF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
LTLEGLRIIYGRNHAS
HHHCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA