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The map label for this gene is ribA [H]

Identifier: 108763825

GI number: 108763825

Start: 143467

End: 144831

Strand: Direct

Name: ribA [H]

Synonym: MXAN_0122

Alternate gene names: 108763825

Gene position: 143467-144831 (Clockwise)

Preceding gene: 108762210

Following gene: 108760567

Centisome position: 1.57

GC content: 70.18

Gene sequence:

>1365_bases
GTGGTCGGCCCGGACCGACGGCTCGTGGATGAGCTGAAGCGCGCCCCACGACGCGAAGCACCGCCCCCCGCACCCCGACT
TTGCTCCCGCGCCCGCAAGGAGGGCGCTCCCATGGCCGAGAAAAAGAATCTCAATCACATCCGCCTCACCTCCCACCCGG
ATGGCGACGTCCCCAGCGTCCCCATCCGCTGGGGAGACGGCGAGCCGACGCGCCGCGGCCCCGTCGTCGCCACGCTGACG
GAAGCCGGGCACCGCAACGTCATCGGCACGCATGCCGGCGCGTATGCCGTGTACCGCGCGCTCGCCGTGGCCGCGGGCAT
GCTGCCGCAGGACCACCGCGCCGACCTGAAGAACACCGCGCCCGCCGCGCAGGTGGGGCCGCATCCGTCGTGGAGCGACC
CGCAGCGCATCGTCTCGCTGGACCCGTGGGGCGCCATCGCGCCGCAGGCGTTCCGGCCCTTCGCGGAGCAGGGCATCGAC
TTCCGGCCGACCATCGCCGTCACCAAGGCGCACATCAACTTCCCCGAGGTGCGCGACGCCATCGATGCCGGGCGCTTGAC
GCCGGACGGGGACCTGCTGCGCGGCAACGGCGACATCAAGGTGACCAAGGCCGCGGTGGACCCGGTGTGGTACCTGCCGG
GCATCGCGAAGCGCTTCGGCATGACGGAGAGCGCGCTGCGCCGTGGTCTCTTCGAGCAGACGGGCGGCATGTTCCCGGAG
CTGATTACGCGCCCGGACCTGCACGTCTTCCTGCCGCCCATTGGCGGGCTGACGCTGTACGTCTTCGGCGGCATCGAGAC
GCTGGCGGACCGGGATGTGCCGCTGACGGTGCGCGTGCATGACGAGTGCAACGGCTCCGACGTGTTCGGCAGCGACATTT
GCACCTGTCGGCCCTACCTGGCGCACGGCATCGAGGAGTGCGTACGCACCGCGCAGGCGGGCGGCGCGGGGCTCATCGTC
TACCTGCGCAAGGAAGGCCGGGCGCTGGGCGAGGTGACGAAGTTCCTCGTGTACAACGCGCGCAAGCGGCAGGAGGGCGG
CGACTCCGCGGCCACCTACTTCCAGCGCACCGAGTGCGTGGCCGGCGTGCAGGACATGCGCTTCCAGGAGCTGATGCCGG
ACGTGCTGCACTGGCTGGGCATCACCCGCATCCACCGCTTCGTATCGATGAGTGACATGAAGCACGACGCGATTACGCGC
TCGGGCATTGAAATCCTGGAGCGCGTCCCCATCCCCGACGAGCTCATCCCCGCCGACGCCAAGGTGGAGATGGAGGCGAA
GAAGGCCGCGGGTTACTTCACGCAAGGGCCGGTGGCGGACGCGGCGGGGCTGGCGCAGGTGAAGGGGCGGGACCTCGATG
TCTGA

Upstream 100 bases:

>100_bases
TCTCCTTCGGTGGCACGGGCGATTCGCGCTTCGGGCACGGGGACATCACCGGGCCGTCCAGCCTCGACTTCTGGACGCAG
GTGAAGAAGGTCACCCGCAA

Downstream 100 bases:

>100_bases
TTTCTCATTGGCCAGGCCGGACCTCTCTCCCGCGGTGGCGTGGCTGCGCACGCCGTCCGCCATCCGCGAGCGGTGCCACC
AACTGTTGGACCTGGGGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: GTP cyclohydrolase II [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MVGPDRRLVDELKRAPRREAPPPAPRLCSRARKEGAPMAEKKNLNHIRLTSHPDGDVPSVPIRWGDGEPTRRGPVVATLT
EAGHRNVIGTHAGAYAVYRALAVAAGMLPQDHRADLKNTAPAAQVGPHPSWSDPQRIVSLDPWGAIAPQAFRPFAEQGID
FRPTIAVTKAHINFPEVRDAIDAGRLTPDGDLLRGNGDIKVTKAAVDPVWYLPGIAKRFGMTESALRRGLFEQTGGMFPE
LITRPDLHVFLPPIGGLTLYVFGGIETLADRDVPLTVRVHDECNGSDVFGSDICTCRPYLAHGIEECVRTAQAGGAGLIV
YLRKEGRALGEVTKFLVYNARKRQEGGDSAATYFQRTECVAGVQDMRFQELMPDVLHWLGITRIHRFVSMSDMKHDAITR
SGIEILERVPIPDELIPADAKVEMEAKKAAGYFTQGPVADAAGLAQVKGRDLDV

Sequences:

>Translated_454_residues
MVGPDRRLVDELKRAPRREAPPPAPRLCSRARKEGAPMAEKKNLNHIRLTSHPDGDVPSVPIRWGDGEPTRRGPVVATLT
EAGHRNVIGTHAGAYAVYRALAVAAGMLPQDHRADLKNTAPAAQVGPHPSWSDPQRIVSLDPWGAIAPQAFRPFAEQGID
FRPTIAVTKAHINFPEVRDAIDAGRLTPDGDLLRGNGDIKVTKAAVDPVWYLPGIAKRFGMTESALRRGLFEQTGGMFPE
LITRPDLHVFLPPIGGLTLYVFGGIETLADRDVPLTVRVHDECNGSDVFGSDICTCRPYLAHGIEECVRTAQAGGAGLIV
YLRKEGRALGEVTKFLVYNARKRQEGGDSAATYFQRTECVAGVQDMRFQELMPDVLHWLGITRIHRFVSMSDMKHDAITR
SGIEILERVPIPDELIPADAKVEMEAKKAAGYFTQGPVADAAGLAQVKGRDLDV
>Mature_454_residues
MVGPDRRLVDELKRAPRREAPPPAPRLCSRARKEGAPMAEKKNLNHIRLTSHPDGDVPSVPIRWGDGEPTRRGPVVATLT
EAGHRNVIGTHAGAYAVYRALAVAAGMLPQDHRADLKNTAPAAQVGPHPSWSDPQRIVSLDPWGAIAPQAFRPFAEQGID
FRPTIAVTKAHINFPEVRDAIDAGRLTPDGDLLRGNGDIKVTKAAVDPVWYLPGIAKRFGMTESALRRGLFEQTGGMFPE
LITRPDLHVFLPPIGGLTLYVFGGIETLADRDVPLTVRVHDECNGSDVFGSDICTCRPYLAHGIEECVRTAQAGGAGLIV
YLRKEGRALGEVTKFLVYNARKRQEGGDSAATYFQRTECVAGVQDMRFQELMPDVLHWLGITRIHRFVSMSDMKHDAITR
SGIEILERVPIPDELIPADAKVEMEAKKAAGYFTQGPVADAAGLAQVKGRDLDV

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0807

COG function: function code H; GTP cyclohydrolase II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase II family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000926 [H]

Pfam domain/function: PF00925 GTP_cyclohydro2 [H]

EC number: =3.5.4.25 [H]

Molecular weight: Translated: 49534; Mature: 49534

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGPDRRLVDELKRAPRREAPPPAPRLCSRARKEGAPMAEKKNLNHIRLTSHPDGDVPSV
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHCCCCEEEEECCCCCCCCCC
PIRWGDGEPTRRGPVVATLTEAGHRNVIGTHAGAYAVYRALAVAAGMLPQDHRADLKNTA
EEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCHHCCC
PAAQVGPHPSWSDPQRIVSLDPWGAIAPQAFRPFAEQGIDFRPTIAVTKAHINFPEVRDA
CCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHH
IDAGRLTPDGDLLRGNGDIKVTKAAVDPVWYLPGIAKRFGMTESALRRGLFEQTGGMFPE
HHHCCCCCCCCEEECCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHH
LITRPDLHVFLPPIGGLTLYVFGGIETLADRDVPLTVRVHDECNGSDVFGSDICTCRPYL
HHCCCCCEEEECCCCCEEEEEECCHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHCCHHH
AHGIEECVRTAQAGGAGLIVYLRKEGRALGEVTKFLVYNARKRQEGGDSAATYFQRTECV
HHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHH
AGVQDMRFQELMPDVLHWLGITRIHRFVSMSDMKHDAITRSGIEILERVPIPDELIPADA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
KVEMEAKKAAGYFTQGPVADAAGLAQVKGRDLDV
CEEEHHHHHCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVGPDRRLVDELKRAPRREAPPPAPRLCSRARKEGAPMAEKKNLNHIRLTSHPDGDVPSV
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHCCCCEEEEECCCCCCCCCC
PIRWGDGEPTRRGPVVATLTEAGHRNVIGTHAGAYAVYRALAVAAGMLPQDHRADLKNTA
EEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCHHCCC
PAAQVGPHPSWSDPQRIVSLDPWGAIAPQAFRPFAEQGIDFRPTIAVTKAHINFPEVRDA
CCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHH
IDAGRLTPDGDLLRGNGDIKVTKAAVDPVWYLPGIAKRFGMTESALRRGLFEQTGGMFPE
HHHCCCCCCCCEEECCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHH
LITRPDLHVFLPPIGGLTLYVFGGIETLADRDVPLTVRVHDECNGSDVFGSDICTCRPYL
HHCCCCCEEEECCCCCEEEEEECCHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHCCHHH
AHGIEECVRTAQAGGAGLIVYLRKEGRALGEVTKFLVYNARKRQEGGDSAATYFQRTECV
HHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHH
AGVQDMRFQELMPDVLHWLGITRIHRFVSMSDMKHDAITRSGIEILERVPIPDELIPADA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
KVEMEAKKAAGYFTQGPVADAAGLAQVKGRDLDV
CEEEHHHHHCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA