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The map label for this gene is yusP [H]

Identifier: 108763799

GI number: 108763799

Start: 1850658

End: 1852001

Strand: Direct

Name: yusP [H]

Synonym: MXAN_1576

Alternate gene names: 108763799

Gene position: 1850658-1852001 (Clockwise)

Preceding gene: 108760532

Following gene: 108760504

Centisome position: 20.25

GC content: 72.69

Gene sequence:

>1344_bases
ATGGTCAGCGCGCGTCCAGGCGTGGCGCGGCGGACAGCGACAGGCGCGGTGTTGCTGGCCCTGGTGGTCAGCGCGTTCGA
AGGCACCGTCGTGACGAGTGCCATGCCCACCATCACCCGGGAGCTGGGAGGTCAGCACCTCTACTCGTGGGTGTTCTCCG
CCTTCCTCTTTGCCTCCACCGTCGGCGTGCTCGTCTCCGGGAAGCTGGCGGACCGGCTGGGACGCAAGCCCGTCTTCTTC
TCGGGCATGGGGTTGTTCCTGGTGGGCTCCGCGCTGTGTGGCCTGGCGGACTCGGTGCCGGGGCTCATTGCCTTCCGGGT
CATCCAGGGCTTGGGCGCGGGCGCGTTGCAGCCCACCACGCTCACCATCTCCGCCGACCTCTACACGCTGCGTGAGCGCG
TCGCCGTGCAGGGGCTGTTCACAGGGGCCTGGGGCGCGGGCAACGTCGTGGGGCCGCTCATTGGCGGCTGGCTGGTGATG
CACGCCTCGTGGCGCTGGGTGTTCCTGGTCAACGTGCCGGTGGGCCTGTTCGCCGCGGCGCTGCTGTACCTCTCCTACCG
CGACCCGCCTCGCCGTCCGGAGGTCCGCATGGACCGGTGGGGGCCCGTGCTCGCGGGCTCCTCGGCGGCGCTGCTCCTCT
TCTCGTTGGAGCCGGGGGCCGCGAGCCTGCGGTGGGCCTGCGCGCTGGCCGCCGTGGGCGCGGGCTGGCTGCTGGTGTGG
CAGCAACGCACGACGGTGTCTCCGTTGCTTCCGGCGGAGTTGCTGAGAGATCGCGCGGTGCTCAGCGGCATCGTGGGCGG
CATCGCGGGCGGCTCGCTGCTGTACAGCATGGCCGCGTGGGTGCCGTTGTGGATGACGGAGCAAGGCGGTCACACGCCAC
TGGCGGCGGGACTGGCGCTGCTGCCGATGCTGCTGGGCTGGTCCGTGGGCTCCACCTTCGGCGTGAAGCTGCTGGTGCGC
GGAGGCATGCGACTGAGCGCCGGCGTGGGCTTCGCGGTGGCGGCGCTGGGGGCCGGGTGGCTGTCATTGGCCGCCGCACG
GGGCTGGGGTGTGCCCGCGGCGCTGATGGGGCTGGCGGTGCTCGGCCTGGGGCTGGGGCCCGCCGCCAGCACGTCGCTGA
TTGGACCGCAGTCCCGCGCGCCCTGGCACCACCGGGGCATCGTCACCAGCGCGCTCTACGCCACGCGGCTTCTGGGCGGC
TCACTGGCGGTGGCGTTGCTCGCGCTGGCCAGCGGGCACTTCGCCCTGCAGTTCGGCATCGCCGCTGGACTCACGGCCGT
CGCGGCGCTCGGGTTGGCGCTGTTGGCTCCGGGCAGGACGGAGCCAGCGGCATCGGGGGCGTGA

Upstream 100 bases:

>100_bases
GCGGATTCCGCAAAAAGCCTATGCGGAAGATGCGGTTTCCGCATGGGGGCCTGGGGCGTACAGAGAGGTAATGGACGGAA
GCGGCGTCACAGCGGAGCCC

Downstream 100 bases:

>100_bases
CAGCGGGCACGTTTCTCTCAGCCCGTGCCGCCTCCCGGGCCCGGTGCTCGGGCGCGCGCGAGGGGCGGCGCCGGTGCTCG
TGCCGCCACCGACGCATCAC

Product: major facilitator family transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MVSARPGVARRTATGAVLLALVVSAFEGTVVTSAMPTITRELGGQHLYSWVFSAFLFASTVGVLVSGKLADRLGRKPVFF
SGMGLFLVGSALCGLADSVPGLIAFRVIQGLGAGALQPTTLTISADLYTLRERVAVQGLFTGAWGAGNVVGPLIGGWLVM
HASWRWVFLVNVPVGLFAAALLYLSYRDPPRRPEVRMDRWGPVLAGSSAALLLFSLEPGAASLRWACALAAVGAGWLLVW
QQRTTVSPLLPAELLRDRAVLSGIVGGIAGGSLLYSMAAWVPLWMTEQGGHTPLAAGLALLPMLLGWSVGSTFGVKLLVR
GGMRLSAGVGFAVAALGAGWLSLAAARGWGVPAALMGLAVLGLGLGPAASTSLIGPQSRAPWHHRGIVTSALYATRLLGG
SLAVALLALASGHFALQFGIAAGLTAVAALGLALLAPGRTEPAASGA

Sequences:

>Translated_447_residues
MVSARPGVARRTATGAVLLALVVSAFEGTVVTSAMPTITRELGGQHLYSWVFSAFLFASTVGVLVSGKLADRLGRKPVFF
SGMGLFLVGSALCGLADSVPGLIAFRVIQGLGAGALQPTTLTISADLYTLRERVAVQGLFTGAWGAGNVVGPLIGGWLVM
HASWRWVFLVNVPVGLFAAALLYLSYRDPPRRPEVRMDRWGPVLAGSSAALLLFSLEPGAASLRWACALAAVGAGWLLVW
QQRTTVSPLLPAELLRDRAVLSGIVGGIAGGSLLYSMAAWVPLWMTEQGGHTPLAAGLALLPMLLGWSVGSTFGVKLLVR
GGMRLSAGVGFAVAALGAGWLSLAAARGWGVPAALMGLAVLGLGLGPAASTSLIGPQSRAPWHHRGIVTSALYATRLLGG
SLAVALLALASGHFALQFGIAAGLTAVAALGLALLAPGRTEPAASGA
>Mature_447_residues
MVSARPGVARRTATGAVLLALVVSAFEGTVVTSAMPTITRELGGQHLYSWVFSAFLFASTVGVLVSGKLADRLGRKPVFF
SGMGLFLVGSALCGLADSVPGLIAFRVIQGLGAGALQPTTLTISADLYTLRERVAVQGLFTGAWGAGNVVGPLIGGWLVM
HASWRWVFLVNVPVGLFAAALLYLSYRDPPRRPEVRMDRWGPVLAGSSAALLLFSLEPGAASLRWACALAAVGAGWLLVW
QQRTTVSPLLPAELLRDRAVLSGIVGGIAGGSLLYSMAAWVPLWMTEQGGHTPLAAGLALLPMLLGWSVGSTFGVKLLVR
GGMRLSAGVGFAVAALGAGWLSLAAARGWGVPAALMGLAVLGLGLGPAASTSLIGPQSRAPWHHRGIVTSALYATRLLGG
SLAVALLALASGHFALQFGIAAGLTAVAALGLALLAPGRTEPAASGA

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1790195, Length=319, Percent_Identity=31.3479623824451, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788710, Length=389, Percent_Identity=28.0205655526992, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081983, Length=422, Percent_Identity=27.9620853080569, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1789042, Length=323, Percent_Identity=28.1733746130031, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788392, Length=316, Percent_Identity=27.8481012658228, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790146, Length=135, Percent_Identity=32.5925925925926, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082320, Length=338, Percent_Identity=24.8520710059172, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322958, Length=185, Percent_Identity=25.4054054054054, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323735, Length=262, Percent_Identity=27.0992366412214, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321663, Length=146, Percent_Identity=27.3972602739726, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6325455, Length=153, Percent_Identity=28.1045751633987, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319770, Length=391, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45718; Mature: 45718

Theoretical pI: Translated: 11.69; Mature: 11.69

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSARPGVARRTATGAVLLALVVSAFEGTVVTSAMPTITRELGGQHLYSWVFSAFLFAST
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
VGVLVSGKLADRLGRKPVFFSGMGLFLVGSALCGLADSVPGLIAFRVIQGLGAGALQPTT
HHHHHCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEE
LTISADLYTLRERVAVQGLFTGAWGAGNVVGPLIGGWLVMHASWRWVFLVNVPVGLFAAA
EEEEHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHH
LLYLSYRDPPRRPEVRMDRWGPVLAGSSAALLLFSLEPGAASLRWACALAAVGAGWLLVW
HHHHHCCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEE
QQRTTVSPLLPAELLRDRAVLSGIVGGIAGGSLLYSMAAWVPLWMTEQGGHTPLAAGLAL
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHH
LPMLLGWSVGSTFGVKLLVRGGMRLSAGVGFAVAALGAGWLSLAAARGWGVPAALMGLAV
HHHHHHCCCCCHHHHHHHEECCCEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LGLGLGPAASTSLIGPQSRAPWHHRGIVTSALYATRLLGGSLAVALLALASGHFALQFGI
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHH
AAGLTAVAALGLALLAPGRTEPAASGA
HHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MVSARPGVARRTATGAVLLALVVSAFEGTVVTSAMPTITRELGGQHLYSWVFSAFLFAST
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
VGVLVSGKLADRLGRKPVFFSGMGLFLVGSALCGLADSVPGLIAFRVIQGLGAGALQPTT
HHHHHCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEE
LTISADLYTLRERVAVQGLFTGAWGAGNVVGPLIGGWLVMHASWRWVFLVNVPVGLFAAA
EEEEHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHH
LLYLSYRDPPRRPEVRMDRWGPVLAGSSAALLLFSLEPGAASLRWACALAAVGAGWLLVW
HHHHHCCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEE
QQRTTVSPLLPAELLRDRAVLSGIVGGIAGGSLLYSMAAWVPLWMTEQGGHTPLAAGLAL
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHH
LPMLLGWSVGSTFGVKLLVRGGMRLSAGVGFAVAALGAGWLSLAAARGWGVPAALMGLAV
HHHHHHCCCCCHHHHHHHEECCCEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LGLGLGPAASTSLIGPQSRAPWHHRGIVTSALYATRLLGGSLAVALLALASGHFALQFGI
HHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHH
AAGLTAVAALGLALLAPGRTEPAASGA
HHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]