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The map label for this gene is acoR [H]

Identifier: 108763720

GI number: 108763720

Start: 6302600

End: 6304813

Strand: Reverse

Name: acoR [H]

Synonym: MXAN_5041

Alternate gene names: 108763720

Gene position: 6304813-6302600 (Counterclockwise)

Preceding gene: 108757746

Following gene: 108762519

Centisome position: 68.98

GC content: 72.18

Gene sequence:

>2214_bases
GTGAGGGGCGACCCATATCTCGTGATGCGCCGCATCAGGTTGGGACAGGAACATTGCGGCGTTCCCAGGTTGTTGCCGCC
ATCGGGATTCAACCAAGATTCGAGGTCCTTGGGGACGCTGACGCTCAGCGCATCACCGCTCCTGTGGGAGCAGTTCCTCG
TGGGGGCACTCGACGGGGAGGCCGGGTTGCGCCCGGAGTTGCGCTCCATCCTCCCCCGCTGGCAGCGCTCACGGTCGCTG
GGCGCCCCGAGCACCGGACAGCCGGACGAAGGGCCCCGTGTGGGCAGCTTGGCGCTGGTCGAGCGCCGGGCCCGGCTGGA
GCCGGTGTGGCACGAGCTGGGCGGCATGTTGGAGATGTTGTCGGCGGCGCCCCTGCCTTCGGGGCGGGTGGCGCTGCTCG
CGGACCGCGAGGGCGTCATCCTGGCGACCCGCAGCTCGGGCGGGGACTTCACCCACCACGCGGATTATGTGCGCCTGGTG
GAGGGGGCCTGCTGGGATGAGACCTCTCGCGGGACGAATGCCATTGGCACTGCCTTGGCGGAGTCCTCCGCCGTCGCGGT
GGTGGGGCCGGCGCACTACGCGCAGCGGCACCATGGGCTCGTCTGCTACGCGGCGCCGGTCCATGACCCCTTTGGAGAGC
TGGTGGCCGTGCTGGACGTCACGGGGCCGGCTGGCGCGGCGGATCCGCTGGTGCTGGTGGCGGTGGCCAGTGTGGCCCAT
GCCGCCGAGGCGCGGCTGCGCGAGGTCGCCTGGGCCCGAGTGGCCGCTGCGGCGCGGGGGGGATTGGAGTCGCGCCTGTC
GCGTGAGGATGGCCCGGTGCTCGTCGTCGAGCCGATGGGGCGGGTGAGTCGCTTCAATGCCGCCGCGCGCGCGTTGCTCG
GTGGACAGGGGCCGATGGCGGTGGAGGCGGCGCTCGGTGTTTCGTGGCGGGTGCTGACGGACGCCGCGTTTCGAGGCGCG
GCGTTGGAGACGCGTCTTGCTTCACAGGGGCCGGCCTGGCGCATCCATGCGGAGGCGGTGGGGACGGGGGATGCGAGCTC
GGCGCTCGCGGTGCTGGTGCGGCTGGAATCTTCTGGTGTCCGGTCCCTGGGCATGACCCCTGGGAGCGCGGATTCACGTC
CGACGGTGGCGGAGCCTTCCACTGAGGGCCGTGGGCCTCGCGCGCTGTCCCGGGACCTGTGGGGGGCGGATACGGTGGTG
CCACCTGGACCGTGGGCGGCGCTCAAGGGGAACGACCCGCAGCACCGCGCCACGTTGCGAGAAGCGGAGCGGTTCGCGCC
CACGAGCTTGCCGGTGCTCCTGCTGTCGGAGACGGGCACGGGCAAGGAGCTCCTCGCTCGCGCACTGCACTCGGCCAGTA
CGGTCGCCACGGGGCCCTTCGTGGCGGTGAACTGCGGCGCGCTGTCGCCCGCGTTGCTGGAGAGTGAACTGTTCGGCCAT
GCGCCTGGTGCCTTCACCGGCGCGCGCGTCGGCGGCGCGGAGGGAAAGCTGGCGGCGGCGGACGGCGGAACGCTCTTCCT
CGACGAGCTGGCGGAGATGCCGCCCGCGCTCCAGGTGTTGTTGCTTCGGGTGCTGGAGGACGGTGCCTATTCGCGCGTGG
GAGAGTCCCGCGTGCGACGCTCGCGCTTCCGCCTGGTGGGCGCCACCTGCAGGGATTTGGACGCGGCCGTGCGCAACGGC
ACGTTCCGCTCCGACCTCTATTTCCGCCTCCAGGGCGCGGTGCTGCGGCTGCCACCGCTGCGCGAGCGCAACGACCTGCC
GGAACTGGCCCATGCACTCCTCCGGAGGTTGTCGGAAGAAGAAGGCCTGGCCACGTCGAGCATCTCCGCCGCTGCGCTCA
CCCGGCTCGCAGCCCACCCCTGGCCCGGCAACGTGCGCGAACTGAAGACAGTGCTGCGGTTGGCGCTGGTGCGCGCGGGA
GGCGCCCCCGTGTTGGACGTGGATGCCCTGCCGTCAGGCCTGGGAAGCCCGCTCTCGCCCGGGGCCCAAGGAGAACCACG
GCCCGCCGTGCCGCCTGTTTCCAGTCCGCCGAGTCAACCGAGCGCGGGTGCCGCCGGCGGTCCGTTGCGCGAGCTGGAGG
CCCGCGCCATCCAGGAGGCCCTGGCGCTCAGTGGCGGCAACGTGGCGCAGGCCGCCCGGCGTCTGGGCATCGCACGGAGC
ACGCTCTACCGGATGGCGGAGCGCTTCGGCATCACGCTGCCCTCGCGCGCCTGA

Upstream 100 bases:

>100_bases
GTCCGGAGGGGGCGGTTGACGTGTCAGCGCCGTGTCGCGTCGCCGCCTGACGCGTCAATGACGTGTCAGGTGAGGTCCCG
GCGCCGGATGTCGAAGGTGG

Downstream 100 bases:

>100_bases
ACGTTCACTGGAGGACGGTGTCCATCGCGCGACGCACCTGTCGCGCTCCGCGCCATGCGTGTCCGGACAGGTGTCGCAGA
GCGGGACACGACGCGCCGCA

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 737; Mature: 737

Protein sequence:

>737_residues
MRGDPYLVMRRIRLGQEHCGVPRLLPPSGFNQDSRSLGTLTLSASPLLWEQFLVGALDGEAGLRPELRSILPRWQRSRSL
GAPSTGQPDEGPRVGSLALVERRARLEPVWHELGGMLEMLSAAPLPSGRVALLADREGVILATRSSGGDFTHHADYVRLV
EGACWDETSRGTNAIGTALAESSAVAVVGPAHYAQRHHGLVCYAAPVHDPFGELVAVLDVTGPAGAADPLVLVAVASVAH
AAEARLREVAWARVAAAARGGLESRLSREDGPVLVVEPMGRVSRFNAAARALLGGQGPMAVEAALGVSWRVLTDAAFRGA
ALETRLASQGPAWRIHAEAVGTGDASSALAVLVRLESSGVRSLGMTPGSADSRPTVAEPSTEGRGPRALSRDLWGADTVV
PPGPWAALKGNDPQHRATLREAERFAPTSLPVLLLSETGTGKELLARALHSASTVATGPFVAVNCGALSPALLESELFGH
APGAFTGARVGGAEGKLAAADGGTLFLDELAEMPPALQVLLLRVLEDGAYSRVGESRVRRSRFRLVGATCRDLDAAVRNG
TFRSDLYFRLQGAVLRLPPLRERNDLPELAHALLRRLSEEEGLATSSISAAALTRLAAHPWPGNVRELKTVLRLALVRAG
GAPVLDVDALPSGLGSPLSPGAQGEPRPAVPPVSSPPSQPSAGAAGGPLRELEARAIQEALALSGGNVAQAARRLGIARS
TLYRMAERFGITLPSRA

Sequences:

>Translated_737_residues
MRGDPYLVMRRIRLGQEHCGVPRLLPPSGFNQDSRSLGTLTLSASPLLWEQFLVGALDGEAGLRPELRSILPRWQRSRSL
GAPSTGQPDEGPRVGSLALVERRARLEPVWHELGGMLEMLSAAPLPSGRVALLADREGVILATRSSGGDFTHHADYVRLV
EGACWDETSRGTNAIGTALAESSAVAVVGPAHYAQRHHGLVCYAAPVHDPFGELVAVLDVTGPAGAADPLVLVAVASVAH
AAEARLREVAWARVAAAARGGLESRLSREDGPVLVVEPMGRVSRFNAAARALLGGQGPMAVEAALGVSWRVLTDAAFRGA
ALETRLASQGPAWRIHAEAVGTGDASSALAVLVRLESSGVRSLGMTPGSADSRPTVAEPSTEGRGPRALSRDLWGADTVV
PPGPWAALKGNDPQHRATLREAERFAPTSLPVLLLSETGTGKELLARALHSASTVATGPFVAVNCGALSPALLESELFGH
APGAFTGARVGGAEGKLAAADGGTLFLDELAEMPPALQVLLLRVLEDGAYSRVGESRVRRSRFRLVGATCRDLDAAVRNG
TFRSDLYFRLQGAVLRLPPLRERNDLPELAHALLRRLSEEEGLATSSISAAALTRLAAHPWPGNVRELKTVLRLALVRAG
GAPVLDVDALPSGLGSPLSPGAQGEPRPAVPPVSSPPSQPSAGAAGGPLRELEARAIQEALALSGGNVAQAARRLGIARS
TLYRMAERFGITLPSRA
>Mature_737_residues
MRGDPYLVMRRIRLGQEHCGVPRLLPPSGFNQDSRSLGTLTLSASPLLWEQFLVGALDGEAGLRPELRSILPRWQRSRSL
GAPSTGQPDEGPRVGSLALVERRARLEPVWHELGGMLEMLSAAPLPSGRVALLADREGVILATRSSGGDFTHHADYVRLV
EGACWDETSRGTNAIGTALAESSAVAVVGPAHYAQRHHGLVCYAAPVHDPFGELVAVLDVTGPAGAADPLVLVAVASVAH
AAEARLREVAWARVAAAARGGLESRLSREDGPVLVVEPMGRVSRFNAAARALLGGQGPMAVEAALGVSWRVLTDAAFRGA
ALETRLASQGPAWRIHAEAVGTGDASSALAVLVRLESSGVRSLGMTPGSADSRPTVAEPSTEGRGPRALSRDLWGADTVV
PPGPWAALKGNDPQHRATLREAERFAPTSLPVLLLSETGTGKELLARALHSASTVATGPFVAVNCGALSPALLESELFGH
APGAFTGARVGGAEGKLAAADGGTLFLDELAEMPPALQVLLLRVLEDGAYSRVGESRVRRSRFRLVGATCRDLDAAVRNG
TFRSDLYFRLQGAVLRLPPLRERNDLPELAHALLRRLSEEEGLATSSISAAALTRLAAHPWPGNVRELKTVLRLALVRAG
GAPVLDVDALPSGLGSPLSPGAQGEPRPAVPPVSSPPSQPSAGAAGGPLRELEARAIQEALALSGGNVAQAARRLGIARS
TLYRMAERFGITLPSRA

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=328, Percent_Identity=39.3292682926829, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI1790437, Length=314, Percent_Identity=40.1273885350318, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1788905, Length=311, Percent_Identity=40.8360128617363, Blast_Score=201, Evalue=2e-52,
Organism=Escherichia coli, GI1789087, Length=345, Percent_Identity=37.1014492753623, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1790299, Length=351, Percent_Identity=39.3162393162393, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI87082152, Length=344, Percent_Identity=38.953488372093, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI87082117, Length=320, Percent_Identity=39.0625, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1789233, Length=316, Percent_Identity=38.2911392405063, Blast_Score=188, Evalue=9e-49,
Organism=Escherichia coli, GI87081872, Length=322, Percent_Identity=39.7515527950311, Blast_Score=179, Evalue=8e-46,
Organism=Escherichia coli, GI1787583, Length=324, Percent_Identity=32.7160493827161, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1786524, Length=329, Percent_Identity=37.9939209726444, Blast_Score=169, Evalue=8e-43,
Organism=Escherichia coli, GI87081858, Length=333, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1789828, Length=247, Percent_Identity=37.6518218623482, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 77098; Mature: 77098

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGDPYLVMRRIRLGQEHCGVPRLLPPSGFNQDSRSLGTLTLSASPLLWEQFLVGALDGE
CCCCHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCC
AGLRPELRSILPRWQRSRSLGAPSTGQPDEGPRVGSLALVERRARLEPVWHELGGMLEML
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
SAAPLPSGRVALLADREGVILATRSSGGDFTHHADYVRLVEGACWDETSRGTNAIGTALA
HHCCCCCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
ESSAVAVVGPAHYAQRHHGLVCYAAPVHDPFGELVAVLDVTGPAGAADPLVLVAVASVAH
CCCCEEEECCHHHHHHHCCEEEEECCCCCCHHHHEEEEECCCCCCCCCHHHHHHHHHHHH
AAEARLREVAWARVAAAARGGLESRLSREDGPVLVVEPMGRVSRFNAAARALLGGQGPMA
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCE
VEAALGVSWRVLTDAAFRGAALETRLASQGPAWRIHAEAVGTGDASSALAVLVRLESSGV
EHHHHCCEEEEHHHHHHCCHHHHHHHHCCCCCEEEEEEEECCCCHHHHEEEEEEECCCCC
RSLGMTPGSADSRPTVAEPSTEGRGPRALSRDLWGADTVVPPGPWAALKGNDPQHRATLR
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEECCCCCHHHHHHHH
EAERFAPTSLPVLLLSETGTGKELLARALHSASTVATGPFVAVNCGALSPALLESELFGH
HHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCC
APGAFTGARVGGAEGKLAAADGGTLFLDELAEMPPALQVLLLRVLEDGAYSRVGESRVRR
CCCCCCCCCCCCCCCCEEECCCCEEHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
SRFRLVGATCRDLDAAVRNGTFRSDLYFRLQGAVLRLPPLRERNDLPELAHALLRRLSEE
HHHHHHCCHHHHHHHHHHCCCCCCCEEEEEECCEEECCCCCCCCCCHHHHHHHHHHHHHH
EGLATSSISAAALTRLAAHPWPGNVRELKTVLRLALVRAGGAPVLDVDALPSGLGSPLSP
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCC
GAQGEPRPAVPPVSSPPSQPSAGAAGGPLRELEARAIQEALALSGGNVAQAARRLGIARS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TLYRMAERFGITLPSRA
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRGDPYLVMRRIRLGQEHCGVPRLLPPSGFNQDSRSLGTLTLSASPLLWEQFLVGALDGE
CCCCHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCC
AGLRPELRSILPRWQRSRSLGAPSTGQPDEGPRVGSLALVERRARLEPVWHELGGMLEML
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
SAAPLPSGRVALLADREGVILATRSSGGDFTHHADYVRLVEGACWDETSRGTNAIGTALA
HHCCCCCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
ESSAVAVVGPAHYAQRHHGLVCYAAPVHDPFGELVAVLDVTGPAGAADPLVLVAVASVAH
CCCCEEEECCHHHHHHHCCEEEEECCCCCCHHHHEEEEECCCCCCCCCHHHHHHHHHHHH
AAEARLREVAWARVAAAARGGLESRLSREDGPVLVVEPMGRVSRFNAAARALLGGQGPMA
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCE
VEAALGVSWRVLTDAAFRGAALETRLASQGPAWRIHAEAVGTGDASSALAVLVRLESSGV
EHHHHCCEEEEHHHHHHCCHHHHHHHHCCCCCEEEEEEEECCCCHHHHEEEEEEECCCCC
RSLGMTPGSADSRPTVAEPSTEGRGPRALSRDLWGADTVVPPGPWAALKGNDPQHRATLR
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEECCCCCHHHHHHHH
EAERFAPTSLPVLLLSETGTGKELLARALHSASTVATGPFVAVNCGALSPALLESELFGH
HHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCC
APGAFTGARVGGAEGKLAAADGGTLFLDELAEMPPALQVLLLRVLEDGAYSRVGESRVRR
CCCCCCCCCCCCCCCCEEECCCCEEHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
SRFRLVGATCRDLDAAVRNGTFRSDLYFRLQGAVLRLPPLRERNDLPELAHALLRRLSEE
HHHHHHCCHHHHHHHHHHCCCCCCCEEEEEECCEEECCCCCCCCCCHHHHHHHHHHHHHH
EGLATSSISAAALTRLAAHPWPGNVRELKTVLRLALVRAGGAPVLDVDALPSGLGSPLSP
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCC
GAQGEPRPAVPPVSSPPSQPSAGAAGGPLRELEARAIQEALALSGGNVAQAARRLGIARS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
TLYRMAERFGITLPSRA
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]