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The map label for this gene is dck [H]

Identifier: 108763441

GI number: 108763441

Start: 3873928

End: 3874542

Strand: Direct

Name: dck [H]

Synonym: MXAN_3331

Alternate gene names: 108763441

Gene position: 3873928-3874542 (Clockwise)

Preceding gene: 108762497

Following gene: 108760839

Centisome position: 42.39

GC content: 61.95

Gene sequence:

>615_bases
GTGGCCAGGAAAAAGTTCATCGCCATCGCGGGCAACATCGGCGCCGGAAAGACGGAGCTGACGTCCTTCCTCTGCCGGAA
GTACGGGTTGACGCCCTCCTTCGAACCCAACGACCAGAACCCCTATCTGGCGGACTTCTACAAGGACATGAAGACGTGGG
CGTTCCGCTCACAGCTCTTCTTCTTGACGCACAAGTTCCGCCTGCACCGGGAGCTGGAGCGCACCTCGGGGACGGTGCTT
CAGGACCGCACCCTCTATGAGGACGCGGAGATTTTCGCCAAGAACCTCCACCGGCAGCGGCTCATCGACAAGCGGGACTG
GAAGACGTACTGCGAGCTGTACGAGACGATTTCGGAGTCGTTGCGGCCCCCCGACCTGATGATCTACCTCCGCTGCCCAG
TGCAGACGATTCGTGAGCGCATCCGCATCCGTGGCCGGGCCATGGAGCGGGACATCCCCACCCGCTACCTGCAGCGCCTC
AATGCCCTCTATGAGGAGTGGTTCGAGGGCTACCGCCTGTCGCCGGTGCTCGTGCTTCCCACGGACAAGCTCGACTATTT
GACCAACCTGGTGGACCGCGTGGACCTCTTCCGGCAGATCGAGAAGCACCTGTGA

Upstream 100 bases:

>100_bases
TTGGACGGGACGACGGGGGGGCATGCACTTCTTCTACCACGTCCTACCTACACGTTGTTTCTGGTGCGCGCCGCTCGGCG
GGGTTACAAGCAGGGGTGGT

Downstream 100 bases:

>100_bases
TGGAGGTCTACCTGCTGGCGACGGAGCAGGAGGGCCCGGCTCCCCTCGATGCACTGCGCACGTCCTTCGCGAACGATGAG
GTGGAGTTCACCCCGGACGC

Product: deoxynucleoside kinase family protein

Products: NA

Alternate protein names: dAK/dCK [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MARKKFIAIAGNIGAGKTELTSFLCRKYGLTPSFEPNDQNPYLADFYKDMKTWAFRSQLFFLTHKFRLHRELERTSGTVL
QDRTLYEDAEIFAKNLHRQRLIDKRDWKTYCELYETISESLRPPDLMIYLRCPVQTIRERIRIRGRAMERDIPTRYLQRL
NALYEEWFEGYRLSPVLVLPTDKLDYLTNLVDRVDLFRQIEKHL

Sequences:

>Translated_204_residues
MARKKFIAIAGNIGAGKTELTSFLCRKYGLTPSFEPNDQNPYLADFYKDMKTWAFRSQLFFLTHKFRLHRELERTSGTVL
QDRTLYEDAEIFAKNLHRQRLIDKRDWKTYCELYETISESLRPPDLMIYLRCPVQTIRERIRIRGRAMERDIPTRYLQRL
NALYEEWFEGYRLSPVLVLPTDKLDYLTNLVDRVDLFRQIEKHL
>Mature_203_residues
ARKKFIAIAGNIGAGKTELTSFLCRKYGLTPSFEPNDQNPYLADFYKDMKTWAFRSQLFFLTHKFRLHRELERTSGTVLQ
DRTLYEDAEIFAKNLHRQRLIDKRDWKTYCELYETISESLRPPDLMIYLRCPVQTIRERIRIRGRAMERDIPTRYLQRLN
ALYEEWFEGYRLSPVLVLPTDKLDYLTNLVDRVDLFRQIEKHL

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the n

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

Organism=Homo sapiens, GI290656975, Length=192, Percent_Identity=28.125, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI290656936, Length=192, Percent_Identity=28.125, Blast_Score=70, Evalue=9e-13,
Organism=Homo sapiens, GI4503269, Length=238, Percent_Identity=25.6302521008403, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI290657203, Length=185, Percent_Identity=26.4864864864865, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17738037, Length=188, Percent_Identity=32.4468085106383, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.74; =2.7.1.76 [H]

Molecular weight: Translated: 24536; Mature: 24404

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKKFIAIAGNIGAGKTELTSFLCRKYGLTPSFEPNDQNPYLADFYKDMKTWAFRSQLF
CCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FLTHKFRLHRELERTSGTVLQDRTLYEDAEIFAKNLHRQRLIDKRDWKTYCELYETISES
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRPPDLMIYLRCPVQTIRERIRIRGRAMERDIPTRYLQRLNALYEEWFEGYRLSPVLVLP
CCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEC
TDKLDYLTNLVDRVDLFRQIEKHL
CCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARKKFIAIAGNIGAGKTELTSFLCRKYGLTPSFEPNDQNPYLADFYKDMKTWAFRSQLF
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FLTHKFRLHRELERTSGTVLQDRTLYEDAEIFAKNLHRQRLIDKRDWKTYCELYETISES
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRPPDLMIYLRCPVQTIRERIRIRGRAMERDIPTRYLQRLNALYEEWFEGYRLSPVLVLP
CCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEC
TDKLDYLTNLVDRVDLFRQIEKHL
CCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]