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The map label for this gene is yusP [H]

Identifier: 108763363

GI number: 108763363

Start: 119698

End: 121449

Strand: Reverse

Name: yusP [H]

Synonym: MXAN_0105

Alternate gene names: 108763363

Gene position: 121449-119698 (Counterclockwise)

Preceding gene: 108759547

Following gene: 108759484

Centisome position: 1.33

GC content: 72.2

Gene sequence:

>1752_bases
ATGGCCCCGTCCGCCGCTCCCGCCACCGCCAATGCGCCGCCCGCCTTCCCGGCGTTCACGCGCTCCCAGAAGGTCTTCAC
GCTGCTGGGCGCGGTGCTGGGGCTCTTGCTCGCCGCGCTGGACCAGACGATTGTCGCCACCGCGGGGCCGGCCATCCAGG
CGGACCTGCGAATCCCCGCCTCGCTCTACCCGTGGCTCACCACGTCGTACTTCGTCGCGTCGACGACGATGGTGCCCGTG
TGGGGCAAGCTGTCGGACCTGCTGGGCCGGCGCGCGGTGTTGGCCGCGGGCATCCTCATCTTCCTCGCGGGCAGCTTCCT
GTGCGGGGTGGCGCGCTCCACGGTGGCGCTCATCCTCTTCCGCGCCGTGCAGGGGCTGGGCAGCGCGGCGCTGTTCACCG
CCGCGCTGGCGGTGGTGGCCGACCTCTTCGAGCCCCGTGAGCGCGGCAAGTACCAGGGCCTCTTCGGCGCCATGTTCGGC
CTGTCCAGCGTGGTGGGGCCGCTGGCCGGTGGGTTCATCACCGACCACCTGGGCTGGCACTGGGTGTTCTTCATCAACCT
GCCCGTGGGCGCGGTGGCGCTGGCGCTGGTGCTGTCGCGCATGCCGCGGCTGAAGCCCCAGCGTGTTTCCCGGGGCGGGC
TGGACCTGGTGGGAGCGTTCACGCTCGCGGTGGCGCTGGTGCCGCTGCTGCTGGCGCTCAGCCTGGGGCAGACGGACGGC
GGCGACTGGGCCTGGACGTCGTGGCGCATCCTGGGACTGTTCGCGCTGTCGGCGGTGGGCCTGGTGGCCTTCCTCTGGGC
GGAGCGGCGCGCGCCCGAGCCCCTGCTCGACCTGACGCTGTTCCGCCTGCGTGCCTTCAGCGCGGGCAACGCGGCGGTGT
TCATCGTCGGCGGGGCGTTCCTGTCGGGCATCGTCTTCCTGCCGCTGTTCATGGTGAACGTGGTGGGGCTGTCGGCGACG
CGCTCGGGGCTGACGGTCATGCCGCTGACGCTGGGCGTGGTGGCGGGGAACGTGCTGAGCGGGCAGCTCGTGTCCAGGGT
GGGCCGCTACAAGGCGCTGCTGCTGGGCTCGCTGGTGCTGCTGATGGCGGGCTTCGCCGTCATGGCCTTCACGCTGACGC
CGGACTCCACCCAGGCGGAGGTGACGGCGAAGATGGTGCTGGTGGGCCTGGGCCTGGGGCCTTCGATTCCGCTCTACACG
ATGGCCATCCAGAACGCGGTGCCACCGGACCAGATTGGCGTGGGCACCGCGGCGGCCACGTTCTTCCGGCAGCTGGGCAT
GACGTTGGGCGTGGCGCTGCTGGGGACGGTGTTCGCGTCCACGCTGTCCTCGGAGCTGGAGGCGCGCATGGCGCAGGCCA
CGTCGGCGCTCCCGGACTCCGTGAAGGCCGAGGTGACACGCGCCGCGCCGGGCGTCAGTGGCGAAGGCGGTCCCACCGGA
CAGGTGTTCCGCGCGGATGAGGTGAAGGCGCGGGTGCGCGCGGAGTTCGACGCCGAGCGGCGCCGTGCGGAGACAACGGC
CGCTCCCGAGGCCCGGGCGAAGGTGGACGCGGACGAGAGACAGGCACTGGCAGCGGTGGACGCGGCGGACCGGGCGCTGA
AGATGGCGTTCACTCGCGGCGTCTCCGCCGTGTACCACGTGGCCCTGTTCATCGCCGGCGCGGCGCTGCTGGTGACACTG
TTCCTTCCGGAGCAGCACCTGCGCCGCAAGCGCCGGCGCATCGAGTCGCGTGCCAGCGCCCCGGAGCAGTAG

Upstream 100 bases:

>100_bases
GGAAACAGCTGGTGCCGCAAAGGGACTCTGCCGGTGGCCGTCTGGTAGGAACGTCCCCACCTTTCCCCTGGCGCCCCTGA
CCCGGGAGCCACCGCGACAC

Downstream 100 bases:

>100_bases
CGTCGCGGCATGGCTCACGACGCGGAACAGTCACCCGCGCTCACGGACGCGGAGGCCGCCGAGCGCATCCACGCGCGCTT
TCCCGCGCTCGCGACGGCGC

Product: EmrB/QacA family drug resistance transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 582

Protein sequence:

>583_residues
MAPSAAPATANAPPAFPAFTRSQKVFTLLGAVLGLLLAALDQTIVATAGPAIQADLRIPASLYPWLTTSYFVASTTMVPV
WGKLSDLLGRRAVLAAGILIFLAGSFLCGVARSTVALILFRAVQGLGSAALFTAALAVVADLFEPRERGKYQGLFGAMFG
LSSVVGPLAGGFITDHLGWHWVFFINLPVGAVALALVLSRMPRLKPQRVSRGGLDLVGAFTLAVALVPLLLALSLGQTDG
GDWAWTSWRILGLFALSAVGLVAFLWAERRAPEPLLDLTLFRLRAFSAGNAAVFIVGGAFLSGIVFLPLFMVNVVGLSAT
RSGLTVMPLTLGVVAGNVLSGQLVSRVGRYKALLLGSLVLLMAGFAVMAFTLTPDSTQAEVTAKMVLVGLGLGPSIPLYT
MAIQNAVPPDQIGVGTAAATFFRQLGMTLGVALLGTVFASTLSSELEARMAQATSALPDSVKAEVTRAAPGVSGEGGPTG
QVFRADEVKARVRAEFDAERRRAETTAAPEARAKVDADERQALAAVDAADRALKMAFTRGVSAVYHVALFIAGAALLVTL
FLPEQHLRRKRRRIESRASAPEQ

Sequences:

>Translated_583_residues
MAPSAAPATANAPPAFPAFTRSQKVFTLLGAVLGLLLAALDQTIVATAGPAIQADLRIPASLYPWLTTSYFVASTTMVPV
WGKLSDLLGRRAVLAAGILIFLAGSFLCGVARSTVALILFRAVQGLGSAALFTAALAVVADLFEPRERGKYQGLFGAMFG
LSSVVGPLAGGFITDHLGWHWVFFINLPVGAVALALVLSRMPRLKPQRVSRGGLDLVGAFTLAVALVPLLLALSLGQTDG
GDWAWTSWRILGLFALSAVGLVAFLWAERRAPEPLLDLTLFRLRAFSAGNAAVFIVGGAFLSGIVFLPLFMVNVVGLSAT
RSGLTVMPLTLGVVAGNVLSGQLVSRVGRYKALLLGSLVLLMAGFAVMAFTLTPDSTQAEVTAKMVLVGLGLGPSIPLYT
MAIQNAVPPDQIGVGTAAATFFRQLGMTLGVALLGTVFASTLSSELEARMAQATSALPDSVKAEVTRAAPGVSGEGGPTG
QVFRADEVKARVRAEFDAERRRAETTAAPEARAKVDADERQALAAVDAADRALKMAFTRGVSAVYHVALFIAGAALLVTL
FLPEQHLRRKRRRIESRASAPEQ
>Mature_582_residues
APSAAPATANAPPAFPAFTRSQKVFTLLGAVLGLLLAALDQTIVATAGPAIQADLRIPASLYPWLTTSYFVASTTMVPVW
GKLSDLLGRRAVLAAGILIFLAGSFLCGVARSTVALILFRAVQGLGSAALFTAALAVVADLFEPRERGKYQGLFGAMFGL
SSVVGPLAGGFITDHLGWHWVFFINLPVGAVALALVLSRMPRLKPQRVSRGGLDLVGAFTLAVALVPLLLALSLGQTDGG
DWAWTSWRILGLFALSAVGLVAFLWAERRAPEPLLDLTLFRLRAFSAGNAAVFIVGGAFLSGIVFLPLFMVNVVGLSATR
SGLTVMPLTLGVVAGNVLSGQLVSRVGRYKALLLGSLVLLMAGFAVMAFTLTPDSTQAEVTAKMVLVGLGLGPSIPLYTM
AIQNAVPPDQIGVGTAAATFFRQLGMTLGVALLGTVFASTLSSELEARMAQATSALPDSVKAEVTRAAPGVSGEGGPTGQ
VFRADEVKARVRAEFDAERRRAETTAAPEARAKVDADERQALAAVDAADRALKMAFTRGVSAVYHVALFIAGAALLVTLF
LPEQHLRRKRRRIESRASAPEQ

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=447, Percent_Identity=25.0559284116331, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87081983, Length=413, Percent_Identity=28.5714285714286, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1790195, Length=411, Percent_Identity=28.2238442822384, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788710, Length=475, Percent_Identity=24.8421052631579, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788392, Length=325, Percent_Identity=32, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87081738, Length=155, Percent_Identity=30.9677419354839, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322958, Length=466, Percent_Identity=27.0386266094421, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6319770, Length=464, Percent_Identity=26.9396551724138, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323735, Length=479, Percent_Identity=25.0521920668058, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319783, Length=382, Percent_Identity=24.869109947644, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6325455, Length=230, Percent_Identity=26.5217391304348, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321663, Length=463, Percent_Identity=21.3822894168467, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324954, Length=396, Percent_Identity=23.4848484848485, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323520, Length=382, Percent_Identity=22.5130890052356, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 61072; Mature: 60941

Theoretical pI: Translated: 10.87; Mature: 10.87

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSAAPATANAPPAFPAFTRSQKVFTLLGAVLGLLLAALDQTIVATAGPAIQADLRIPA
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
SLYPWLTTSYFVASTTMVPVWGKLSDLLGRRAVLAAGILIFLAGSFLCGVARSTVALILF
HHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVQGLGSAALFTAALAVVADLFEPRERGKYQGLFGAMFGLSSVVGPLAGGFITDHLGWH
HHHHCCCHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCE
WVFFINLPVGAVALALVLSRMPRLKPQRVSRGGLDLVGAFTLAVALVPLLLALSLGQTDG
EEEEEECCHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
GDWAWTSWRILGLFALSAVGLVAFLWAERRAPEPLLDLTLFRLRAFSAGNAAVFIVGGAF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEECHHH
LSGIVFLPLFMVNVVGLSATRSGLTVMPLTLGVVAGNVLSGQLVSRVGRYKALLLGSLVL
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMAGFAVMAFTLTPDSTQAEVTAKMVLVGLGLGPSIPLYTMAIQNAVPPDQIGVGTAAAT
HHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHH
FFRQLGMTLGVALLGTVFASTLSSELEARMAQATSALPDSVKAEVTRAAPGVSGEGGPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC
QVFRADEVKARVRAEFDAERRRAETTAAPEARAKVDADERQALAAVDAADRALKMAFTRG
CEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VSAVYHVALFIAGAALLVTLFLPEQHLRRKRRRIESRASAPEQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
APSAAPATANAPPAFPAFTRSQKVFTLLGAVLGLLLAALDQTIVATAGPAIQADLRIPA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
SLYPWLTTSYFVASTTMVPVWGKLSDLLGRRAVLAAGILIFLAGSFLCGVARSTVALILF
HHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAVQGLGSAALFTAALAVVADLFEPRERGKYQGLFGAMFGLSSVVGPLAGGFITDHLGWH
HHHHCCCHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCE
WVFFINLPVGAVALALVLSRMPRLKPQRVSRGGLDLVGAFTLAVALVPLLLALSLGQTDG
EEEEEECCHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
GDWAWTSWRILGLFALSAVGLVAFLWAERRAPEPLLDLTLFRLRAFSAGNAAVFIVGGAF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEECHHH
LSGIVFLPLFMVNVVGLSATRSGLTVMPLTLGVVAGNVLSGQLVSRVGRYKALLLGSLVL
HHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMAGFAVMAFTLTPDSTQAEVTAKMVLVGLGLGPSIPLYTMAIQNAVPPDQIGVGTAAAT
HHHHHHHHEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHH
FFRQLGMTLGVALLGTVFASTLSSELEARMAQATSALPDSVKAEVTRAAPGVSGEGGPTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCC
QVFRADEVKARVRAEFDAERRRAETTAAPEARAKVDADERQALAAVDAADRALKMAFTRG
CEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VSAVYHVALFIAGAALLVTLFLPEQHLRRKRRRIESRASAPEQ
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]