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The map label for this gene is cysH [H]

Identifier: 108763333

GI number: 108763333

Start: 2720032

End: 2720754

Strand: Reverse

Name: cysH [H]

Synonym: MXAN_2340

Alternate gene names: 108763333

Gene position: 2720754-2720032 (Counterclockwise)

Preceding gene: 108760604

Following gene: 108756853

Centisome position: 29.77

GC content: 70.26

Gene sequence:

>723_bases
ATGTCGCCCCCGCAGCCCCAGGCCTCGGCCCTGCTCGCCGAAGCCGCTGAAGTGAAGGACGCCCCCGCGCAGGACCTCCT
CGCCTGGACCGAGCGCCGCTTCGGTGCGCGCGCGGCCATCGCCTCCAGCTTCGGCGTGGAGGACATGGTCCTCATCGACC
TGGCGCGCCAGCATGCGCCCAGCCTGCGCCTCTTCACGCTCGACACCGGACGCCTGCCCCCGGAGACGTACGAACTCATG
GAGGTGGTGCGTAAGCGCTACGGCGTCACCGTGGAGACGTACTTCCCCGAGCGCGCGCGCGTGGAGGCGTTGGAGTCCAC
GAACGGCTACTTCTCCTTCCGCCAGAGCCTAGAGGCACGCAAGGCGTGCTGCGCCATCCGCAAGGTGGAGCCCCTGTCGC
GCGCGCTCGCGGGTCAACAGGCGTGGGTGACGGGATTGCGCCGTGAGCAGTCCGTCACCCGCACCGACGTGGCGACGTTA
GAGGTGGACAGCGCGCATGGGCTGCTCAAGCTCAACCCGCTGGCCACGTGGAGCAGCCGGGACATCTGGGCCTACGTCCG
GGCGAAGAGCGTGCCCTACAACGCGCTCCATGACCGTGGCTACCCGTCCATCGGCTGTGCGCCCTGCACGCGCGCGGTGA
AACCCTACGAGGACGAGCGCGCGGGCCGCTGGTGGTGGGAGTCCGCGGAGAACCGCGAGTGCGGCCTCCACCCGGTCCGA
TGA

Upstream 100 bases:

>100_bases
TGCCGAGCATCGAGAAGCGTGTAGCGCGTCCTTCTCGAACCTTCTTGCTCGTGCGGCCCGCCCTCGAAAGAGGCGGGCCT
TTTCTTTTCCTGGAGTCACC

Downstream 100 bases:

>100_bases
AACACGCCATGCCTTCACACCCCCTGGATTATCCCGTGTGCCTTCGACTCGAGGGACGCTCCGTCCTGCTGGTGGGCGGC
GGCGCCATCGCGGAGGGCCG

Product: putative adenylylsulfate reductase, thioredoxin dependent

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSPPQPQASALLAEAAEVKDAPAQDLLAWTERRFGARAAIASSFGVEDMVLIDLARQHAPSLRLFTLDTGRLPPETYELM
EVVRKRYGVTVETYFPERARVEALESTNGYFSFRQSLEARKACCAIRKVEPLSRALAGQQAWVTGLRREQSVTRTDVATL
EVDSAHGLLKLNPLATWSSRDIWAYVRAKSVPYNALHDRGYPSIGCAPCTRAVKPYEDERAGRWWWESAENRECGLHPVR

Sequences:

>Translated_240_residues
MSPPQPQASALLAEAAEVKDAPAQDLLAWTERRFGARAAIASSFGVEDMVLIDLARQHAPSLRLFTLDTGRLPPETYELM
EVVRKRYGVTVETYFPERARVEALESTNGYFSFRQSLEARKACCAIRKVEPLSRALAGQQAWVTGLRREQSVTRTDVATL
EVDSAHGLLKLNPLATWSSRDIWAYVRAKSVPYNALHDRGYPSIGCAPCTRAVKPYEDERAGRWWWESAENRECGLHPVR
>Mature_239_residues
SPPQPQASALLAEAAEVKDAPAQDLLAWTERRFGARAAIASSFGVEDMVLIDLARQHAPSLRLFTLDTGRLPPETYELME
VVRKRYGVTVETYFPERARVEALESTNGYFSFRQSLEARKACCAIRKVEPLSRALAGQQAWVTGLRREQSVTRTDVATLE
VDSAHGLLKLNPLATWSSRDIWAYVRAKSVPYNALHDRGYPSIGCAPCTRAVKPYEDERAGRWWWESAENRECGLHPVR

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=238, Percent_Identity=31.9327731092437, Blast_Score=111, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6325425, Length=232, Percent_Identity=33.6206896551724, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 26962; Mature: 26831

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPPQPQASALLAEAAEVKDAPAQDLLAWTERRFGARAAIASSFGVEDMVLIDLARQHAP
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHCCC
SLRLFTLDTGRLPPETYELMEVVRKRYGVTVETYFPERARVEALESTNGYFSFRQSLEAR
CEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCHHHHHHHHHHH
KACCAIRKVEPLSRALAGQQAWVTGLRREQSVTRTDVATLEVDSAHGLLKLNPLATWSSR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCCCCC
DIWAYVRAKSVPYNALHDRGYPSIGCAPCTRAVKPYEDERAGRWWWESAENRECGLHPVR
CEEEEEEECCCCCHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPPQPQASALLAEAAEVKDAPAQDLLAWTERRFGARAAIASSFGVEDMVLIDLARQHAP
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHHCCC
SLRLFTLDTGRLPPETYELMEVVRKRYGVTVETYFPERARVEALESTNGYFSFRQSLEAR
CEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCHHHHHHHHHHH
KACCAIRKVEPLSRALAGQQAWVTGLRREQSVTRTDVATLEVDSAHGLLKLNPLATWSSR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCCCCC
DIWAYVRAKSVPYNALHDRGYPSIGCAPCTRAVKPYEDERAGRWWWESAENRECGLHPVR
CEEEEEEECCCCCHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA