| Definition | Myxococcus xanthus DK 1622 chromosome, complete genome. |
|---|---|
| Accession | NC_008095 |
| Length | 9,139,763 |
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The map label for this gene is lcfB [H]
Identifier: 108763218
GI number: 108763218
Start: 273221
End: 274738
Strand: Direct
Name: lcfB [H]
Synonym: MXAN_0225
Alternate gene names: 108763218
Gene position: 273221-274738 (Clockwise)
Preceding gene: 108758562
Following gene: 108759823
Centisome position: 2.99
GC content: 69.17
Gene sequence:
>1518_bases ATGCCCATCGTCCATGACTGGCTGGCCCGGCGTGCCGCGCTGGCCCCTGAGCGTACCGCCCTCATCGACGCCGACCATGG CGAGCGACGCATCTCCTTTCGTGAATGGAACGATTCGGCTTCGCGTACCGCCGCTTTCCTCCACCATGCGCTGGGTGTGG GGCGAGGGGACCGTGTCGCGGTGCTCGCCTACAACTGCGTCGAGTTCCTCGACCTCTTCTTCGCGTGCGCGAAGCTGGGC GCCGTCCTTCAGCCTCTCAACTGGCGGCTGAGTGCCACGGAGCTGGGGGGGCTGCTCGCGGATGCCGAGCCATCCGTGTT CGTCTTCGGGCCGGAGTTCCGAACCCAGGTGGAGGCCGTGCGGTCTGGCGCGTCCTTCGTGCGCCACTGGCTCAGTCTCG CGGCTCCAGGGCCGAGCGAGCGGGCCTTCTCCGAGCGCGACACGCAGACGGACGTGGCCCTTCCTCCGCTGGAGCTAGAG GAGGATGCTCCATGGGTGCTCTGCTACACGGGCGGAAGCACCGGTCTGCCGAAGGCCGCGGTGCTCACGCACCGCTCCAT CACCGCCAACGCGGTGAACACGGTGATGGGCTGGGGCCTGACCGCCGATGACGTGGCGATCCTCAACGCGCCGTTGTTCC ATGCCGGAGGACTCAGCGTCTTCACCGCGCCGCTGGCCTACGCCGGCGGCGCATCGGTGGTGTGCCGGAGCTTCGATGTG GAGGGCGTGTTCGACCTCGTGCGGCGGGGCGTGGTGAGTCTCTTCTTCGGTGTGCCCACCATGTTCATCGAGATGCAGCG CCACCCGCGTTTCGATGCCGTGGACCTGTCACGCCTCAAGCTGGTCATCAGCGGCGGCGCGCCCTGCCCGGCCCCCGTTT TCGAGCGCTTCTTCGCTCGGGGCGTGGACTTCAAGACGGGGTATGGCCTCACCGAAGCGGGCCCCAACAACTTCTGGCTT CCACCGGAAGACGTGCGCCGCAAGCCAGGGGCGGTGGGCGTGCCCCTGTTCCACGTCGAGGCTCGCATCGACGGTGAGAC GCAGCCGGGCGACGTGGGCGAGCTGCTCTTGCGAGGCCCTCACCTGTGTGCGGGCTACTGGCGCCGTCCGGGGGACACTG CCCGCACCTTCGCGGACGGCTGGCTGCACACCGGTGACCTGGCCACGCGGGACGCGGAGGGATGCTTCCGCATCGTGGGC CGCAGCAAGGACCTCATCATCTCCGGCGGTGAGAACATCTACCCGTCGGAAGTGGAGAGCGTCCTCGCGGGGCATCCCGA TGTGGCCGAGGTCGCCGTCATCGGCGTGGCGGACCCCAAGTGGGGGGAGACGCCGCGCGCGCTCGTCGTCGCACGGCCGG GCACCTCGCCTTCGGCTGAGGCCCTGCTGCGCTTCTGCGACGGACGGCTCGCTCGATACAAGACGCCGAAGTCGATTCGT TTCGTGGACGCCCTGCCGAGGACCTCCGCCGGCAAGGTTGACCGGCGCACGCTCGGTGCCGCGCACGGCGCGCCCTGA
Upstream 100 bases:
>100_bases CCCTCCGAGCGGGTGGGGAGGTGACGGTGAGGCGGGTTGCTTGCCCGCTTCCCTTTCCTGAGCCGACGCGATGCCGCCGG GTTCAGCTAGCGTGGATACC
Downstream 100 bases:
>100_bases GTTGCCCACAAGTCCTCCCCAGGCCCGTGTCCCTGGCGGCTGCGCATCCGTTCGTGCGTTGCCGCTGGCTTCTTCACGGA CCTGGGGGGCATTGGCCTCC
Product: putative long-chain-fatty-acid--CoA ligase
Products: NA
Alternate protein names: Long-chain acyl-CoA synthetase [H]
Number of amino acids: Translated: 505; Mature: 504
Protein sequence:
>505_residues MPIVHDWLARRAALAPERTALIDADHGERRISFREWNDSASRTAAFLHHALGVGRGDRVAVLAYNCVEFLDLFFACAKLG AVLQPLNWRLSATELGGLLADAEPSVFVFGPEFRTQVEAVRSGASFVRHWLSLAAPGPSERAFSERDTQTDVALPPLELE EDAPWVLCYTGGSTGLPKAAVLTHRSITANAVNTVMGWGLTADDVAILNAPLFHAGGLSVFTAPLAYAGGASVVCRSFDV EGVFDLVRRGVVSLFFGVPTMFIEMQRHPRFDAVDLSRLKLVISGGAPCPAPVFERFFARGVDFKTGYGLTEAGPNNFWL PPEDVRRKPGAVGVPLFHVEARIDGETQPGDVGELLLRGPHLCAGYWRRPGDTARTFADGWLHTGDLATRDAEGCFRIVG RSKDLIISGGENIYPSEVESVLAGHPDVAEVAVIGVADPKWGETPRALVVARPGTSPSAEALLRFCDGRLARYKTPKSIR FVDALPRTSAGKVDRRTLGAAHGAP
Sequences:
>Translated_505_residues MPIVHDWLARRAALAPERTALIDADHGERRISFREWNDSASRTAAFLHHALGVGRGDRVAVLAYNCVEFLDLFFACAKLG AVLQPLNWRLSATELGGLLADAEPSVFVFGPEFRTQVEAVRSGASFVRHWLSLAAPGPSERAFSERDTQTDVALPPLELE EDAPWVLCYTGGSTGLPKAAVLTHRSITANAVNTVMGWGLTADDVAILNAPLFHAGGLSVFTAPLAYAGGASVVCRSFDV EGVFDLVRRGVVSLFFGVPTMFIEMQRHPRFDAVDLSRLKLVISGGAPCPAPVFERFFARGVDFKTGYGLTEAGPNNFWL PPEDVRRKPGAVGVPLFHVEARIDGETQPGDVGELLLRGPHLCAGYWRRPGDTARTFADGWLHTGDLATRDAEGCFRIVG RSKDLIISGGENIYPSEVESVLAGHPDVAEVAVIGVADPKWGETPRALVVARPGTSPSAEALLRFCDGRLARYKTPKSIR FVDALPRTSAGKVDRRTLGAAHGAP >Mature_504_residues PIVHDWLARRAALAPERTALIDADHGERRISFREWNDSASRTAAFLHHALGVGRGDRVAVLAYNCVEFLDLFFACAKLGA VLQPLNWRLSATELGGLLADAEPSVFVFGPEFRTQVEAVRSGASFVRHWLSLAAPGPSERAFSERDTQTDVALPPLELEE DAPWVLCYTGGSTGLPKAAVLTHRSITANAVNTVMGWGLTADDVAILNAPLFHAGGLSVFTAPLAYAGGASVVCRSFDVE GVFDLVRRGVVSLFFGVPTMFIEMQRHPRFDAVDLSRLKLVISGGAPCPAPVFERFFARGVDFKTGYGLTEAGPNNFWLP PEDVRRKPGAVGVPLFHVEARIDGETQPGDVGELLLRGPHLCAGYWRRPGDTARTFADGWLHTGDLATRDAEGCFRIVGR SKDLIISGGENIYPSEVESVLAGHPDVAEVAVIGVADPKWGETPRALVVARPGTSPSAEALLRFCDGRLARYKTPKSIRF VDALPRTSAGKVDRRTLGAAHGAP
Specific function: Involved in the degradation of long-chain fatty acids [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Partially Membrane-Associated [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]
Homologues:
Organism=Homo sapiens, GI156151445, Length=539, Percent_Identity=30.9833024118738, Blast_Score=223, Evalue=3e-58, Organism=Homo sapiens, GI187761345, Length=536, Percent_Identity=30.2238805970149, Blast_Score=175, Evalue=8e-44, Organism=Homo sapiens, GI187761343, Length=536, Percent_Identity=30.2238805970149, Blast_Score=175, Evalue=8e-44, Organism=Homo sapiens, GI42544132, Length=528, Percent_Identity=27.2727272727273, Blast_Score=140, Evalue=2e-33, Organism=Homo sapiens, GI157311624, Length=505, Percent_Identity=26.9306930693069, Blast_Score=136, Evalue=5e-32, Organism=Homo sapiens, GI157311622, Length=505, Percent_Identity=26.9306930693069, Blast_Score=136, Evalue=5e-32, Organism=Homo sapiens, GI58082049, Length=502, Percent_Identity=27.2908366533865, Blast_Score=135, Evalue=6e-32, Organism=Homo sapiens, GI122937307, Length=499, Percent_Identity=28.0561122244489, Blast_Score=128, Evalue=1e-29, Organism=Homo sapiens, GI115511026, Length=503, Percent_Identity=25.2485089463221, Blast_Score=122, Evalue=1e-27, Organism=Homo sapiens, GI38505220, Length=499, Percent_Identity=25.250501002004, Blast_Score=119, Evalue=5e-27, Organism=Homo sapiens, GI28416953, Length=542, Percent_Identity=25.2767527675277, Blast_Score=101, Evalue=2e-21, Organism=Homo sapiens, GI13325057, Length=541, Percent_Identity=26.9870609981516, Blast_Score=100, Evalue=4e-21, Organism=Homo sapiens, GI227499619, Length=514, Percent_Identity=23.5408560311284, Blast_Score=92, Evalue=2e-18, Organism=Homo sapiens, GI13375727, Length=543, Percent_Identity=23.7569060773481, Blast_Score=86, Evalue=9e-17, Organism=Homo sapiens, GI40807491, Length=358, Percent_Identity=27.0949720670391, Blast_Score=84, Evalue=3e-16, Organism=Homo sapiens, GI8923896, Length=551, Percent_Identity=23.7749546279492, Blast_Score=80, Evalue=4e-15, Organism=Homo sapiens, GI253970489, Length=367, Percent_Identity=27.5204359673025, Blast_Score=76, Evalue=7e-14, Organism=Homo sapiens, GI27477105, Length=168, Percent_Identity=30.952380952381, Blast_Score=69, Evalue=1e-11, Organism=Escherichia coli, GI1788107, Length=505, Percent_Identity=32.4752475247525, Blast_Score=242, Evalue=4e-65, Organism=Escherichia coli, GI221142682, Length=501, Percent_Identity=29.940119760479, Blast_Score=205, Evalue=4e-54, Organism=Escherichia coli, GI145693145, Length=511, Percent_Identity=29.9412915851272, Blast_Score=191, Evalue=1e-49, Organism=Escherichia coli, GI1786810, Length=529, Percent_Identity=30.0567107750473, Blast_Score=141, Evalue=8e-35, Organism=Escherichia coli, GI1786529, Length=558, Percent_Identity=26.1648745519713, Blast_Score=107, Evalue=2e-24, Organism=Escherichia coli, GI1788595, Length=336, Percent_Identity=30.3571428571429, Blast_Score=106, Evalue=4e-24, Organism=Escherichia coli, GI1790505, Length=558, Percent_Identity=24.3727598566308, Blast_Score=101, Evalue=1e-22, Organism=Escherichia coli, GI1789201, Length=356, Percent_Identity=28.0898876404494, Blast_Score=99, Evalue=5e-22, Organism=Escherichia coli, GI1786801, Length=529, Percent_Identity=26.2759924385633, Blast_Score=79, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17558820, Length=506, Percent_Identity=31.0276679841897, Blast_Score=236, Evalue=2e-62, Organism=Caenorhabditis elegans, GI32563687, Length=502, Percent_Identity=30.4780876494024, Blast_Score=219, Evalue=2e-57, Organism=Caenorhabditis elegans, GI71994690, Length=541, Percent_Identity=29.3900184842884, Blast_Score=188, Evalue=4e-48, Organism=Caenorhabditis elegans, GI71994703, Length=541, Percent_Identity=29.3900184842884, Blast_Score=188, Evalue=5e-48, Organism=Caenorhabditis elegans, GI71994694, Length=541, Percent_Identity=29.3900184842884, Blast_Score=188, Evalue=5e-48, Organism=Caenorhabditis elegans, GI17560308, Length=522, Percent_Identity=31.0344827586207, Blast_Score=182, Evalue=3e-46, Organism=Caenorhabditis elegans, GI17559526, Length=521, Percent_Identity=27.2552783109405, Blast_Score=179, Evalue=2e-45, Organism=Caenorhabditis elegans, GI17531443, Length=527, Percent_Identity=25.6166982922201, Blast_Score=166, Evalue=2e-41, Organism=Caenorhabditis elegans, GI17557194, Length=523, Percent_Identity=28.2982791586998, Blast_Score=154, Evalue=1e-37, Organism=Caenorhabditis elegans, GI17538037, Length=521, Percent_Identity=28.5988483685221, Blast_Score=145, Evalue=4e-35, Organism=Caenorhabditis elegans, GI71996755, Length=513, Percent_Identity=25.3411306042885, Blast_Score=123, Evalue=2e-28, Organism=Caenorhabditis elegans, GI71985884, Length=364, Percent_Identity=29.1208791208791, Blast_Score=119, Evalue=5e-27, Organism=Caenorhabditis elegans, GI17560140, Length=523, Percent_Identity=24.0917782026769, Blast_Score=115, Evalue=4e-26, Organism=Caenorhabditis elegans, GI25141359, Length=502, Percent_Identity=22.7091633466135, Blast_Score=94, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17564090, Length=339, Percent_Identity=24.7787610619469, Blast_Score=82, Evalue=8e-16, Organism=Caenorhabditis elegans, GI71982997, Length=515, Percent_Identity=24.2718446601942, Blast_Score=67, Evalue=3e-11, Organism=Caenorhabditis elegans, GI71983001, Length=515, Percent_Identity=24.2718446601942, Blast_Score=67, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6319699, Length=484, Percent_Identity=29.3388429752066, Blast_Score=161, Evalue=2e-40, Organism=Saccharomyces cerevisiae, GI6323182, Length=559, Percent_Identity=27.0125223613596, Blast_Score=116, Evalue=1e-26, Organism=Saccharomyces cerevisiae, GI6319264, Length=558, Percent_Identity=24.5519713261649, Blast_Score=106, Evalue=7e-24, Organism=Saccharomyces cerevisiae, GI6323903, Length=326, Percent_Identity=27.3006134969325, Blast_Score=87, Evalue=5e-18, Organism=Saccharomyces cerevisiae, GI6322182, Length=360, Percent_Identity=25.2777777777778, Blast_Score=82, Evalue=1e-16, Organism=Saccharomyces cerevisiae, GI6320852, Length=176, Percent_Identity=28.9772727272727, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI21355181, Length=504, Percent_Identity=30.5555555555556, Blast_Score=185, Evalue=8e-47, Organism=Drosophila melanogaster, GI18859661, Length=359, Percent_Identity=33.983286908078, Blast_Score=164, Evalue=1e-40, Organism=Drosophila melanogaster, GI24581924, Length=349, Percent_Identity=33.5243553008596, Blast_Score=164, Evalue=2e-40, Organism=Drosophila melanogaster, GI21358303, Length=479, Percent_Identity=26.9311064718163, Blast_Score=142, Evalue=4e-34, Organism=Drosophila melanogaster, GI21356441, Length=495, Percent_Identity=27.6767676767677, Blast_Score=141, Evalue=1e-33, Organism=Drosophila melanogaster, GI281365686, Length=477, Percent_Identity=25.1572327044025, Blast_Score=130, Evalue=2e-30, Organism=Drosophila melanogaster, GI24656500, Length=481, Percent_Identity=26.8191268191268, Blast_Score=123, Evalue=3e-28, Organism=Drosophila melanogaster, GI24648253, Length=496, Percent_Identity=26.008064516129, Blast_Score=122, Evalue=8e-28, Organism=Drosophila melanogaster, GI24648255, Length=496, Percent_Identity=26.2096774193548, Blast_Score=121, Evalue=1e-27, Organism=Drosophila melanogaster, GI20130357, Length=477, Percent_Identity=25.5765199161426, Blast_Score=120, Evalue=3e-27, Organism=Drosophila melanogaster, GI19922652, Length=469, Percent_Identity=25.3731343283582, Blast_Score=115, Evalue=6e-26, Organism=Drosophila melanogaster, GI24648260, Length=459, Percent_Identity=25.2723311546841, Blast_Score=114, Evalue=2e-25, Organism=Drosophila melanogaster, GI24653035, Length=489, Percent_Identity=23.1083844580777, Blast_Score=113, Evalue=3e-25, Organism=Drosophila melanogaster, GI24648257, Length=509, Percent_Identity=24.5579567779961, Blast_Score=112, Evalue=5e-25, Organism=Drosophila melanogaster, GI161076582, Length=495, Percent_Identity=23.030303030303, Blast_Score=103, Evalue=4e-22, Organism=Drosophila melanogaster, GI21356947, Length=463, Percent_Identity=25.2699784017279, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI19921316, Length=487, Percent_Identity=23.2032854209446, Blast_Score=89, Evalue=5e-18, Organism=Drosophila melanogaster, GI62472339, Length=529, Percent_Identity=23.2514177693762, Blast_Score=86, Evalue=5e-17, Organism=Drosophila melanogaster, GI24667955, Length=529, Percent_Identity=23.2514177693762, Blast_Score=86, Evalue=8e-17, Organism=Drosophila melanogaster, GI24667959, Length=380, Percent_Identity=25, Blast_Score=78, Evalue=2e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020459 - InterPro: IPR020845 - InterPro: IPR000873 [H]
Pfam domain/function: PF00501 AMP-binding [H]
EC number: =6.2.1.3 [H]
Molecular weight: Translated: 54434; Mature: 54303
Theoretical pI: Translated: 6.70; Mature: 6.70
Prosite motif: PS00455 AMP_BINDING
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 0.6 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPIVHDWLARRAALAPERTALIDADHGERRISFREWNDSASRTAAFLHHALGVGRGDRVA CCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEE VLAYNCVEFLDLFFACAKLGAVLQPLNWRLSATELGGLLADAEPSVFVFGPEFRTQVEAV EEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCCEEECCCCCEEEECCHHHHHHHHH RSGASFVRHWLSLAAPGPSERAFSERDTQTDVALPPLELEEDAPWVLCYTGGSTGLPKAA HHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHH VLTHRSITANAVNTVMGWGLTADDVAILNAPLFHAGGLSVFTAPLAYAGGASVVCRSFDV HEECCCCHHHHHHHHHCCCCCCCCHHEECCCCCCCCCHHHHHHHHHHCCCHHEEEECCCC EGVFDLVRRGVVSLFFGVPTMFIEMQRHPRFDAVDLSRLKLVISGGAPCPAPVFERFFAR HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHEEEEEECCCCCCHHHHHHHHHC GVDFKTGYGLTEAGPNNFWLPPEDVRRKPGAVGVPLFHVEARIDGETQPGDVGELLLRGP CCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHCCC HLCAGYWRRPGDTARTFADGWLHTGDLATRDAEGCFRIVGRSKDLIISGGENIYPSEVES CHHHHHCCCCCCHHHHHHCCCEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHH VLAGHPDVAEVAVIGVADPKWGETPRALVVARPGTSPSAEALLRFCDGRLARYKTPKSIR HHCCCCCHHHEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCHHHHCCCCCCEE FVDALPRTSAGKVDRRTLGAAHGAP EEECCCCCCCCCCHHHHHCCCCCCC >Mature Secondary Structure PIVHDWLARRAALAPERTALIDADHGERRISFREWNDSASRTAAFLHHALGVGRGDRVA CCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEE VLAYNCVEFLDLFFACAKLGAVLQPLNWRLSATELGGLLADAEPSVFVFGPEFRTQVEAV EEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCCEEECCCCCEEEECCHHHHHHHHH RSGASFVRHWLSLAAPGPSERAFSERDTQTDVALPPLELEEDAPWVLCYTGGSTGLPKAA HHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHH VLTHRSITANAVNTVMGWGLTADDVAILNAPLFHAGGLSVFTAPLAYAGGASVVCRSFDV HEECCCCHHHHHHHHHCCCCCCCCHHEECCCCCCCCCHHHHHHHHHHCCCHHEEEECCCC EGVFDLVRRGVVSLFFGVPTMFIEMQRHPRFDAVDLSRLKLVISGGAPCPAPVFERFFAR HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHEEEEEECCCCCCHHHHHHHHHC GVDFKTGYGLTEAGPNNFWLPPEDVRRKPGAVGVPLFHVEARIDGETQPGDVGELLLRGP CCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHCCC HLCAGYWRRPGDTARTFADGWLHTGDLATRDAEGCFRIVGRSKDLIISGGENIYPSEVES CHHHHHCCCCCCHHHHHHCCCEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHH VLAGHPDVAEVAVIGVADPKWGETPRALVVARPGTSPSAEALLRFCDGRLARYKTPKSIR HHCCCCCHHHEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCHHHHCCCCCCEE FVDALPRTSAGKVDRRTLGAAHGAP EEECCCCCCCCCCHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9579061; 9384377 [H]