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The map label for this gene is clpB [H]

Identifier: 108763122

GI number: 108763122

Start: 6362719

End: 6365343

Strand: Direct

Name: clpB [H]

Synonym: MXAN_5092

Alternate gene names: 108763122

Gene position: 6362719-6365343 (Clockwise)

Preceding gene: 108761517

Following gene: 108762668

Centisome position: 69.62

GC content: 67.92

Gene sequence:

>2625_bases
ATGCGACTCGACAAGTACACAGTGAAGGCGCAGGAGGCGATCCACGAGGGTCAGAGCCTGGCCCGTCGGGCGGACAATCC
GCAGTACGAGCCCGAGCACCTGGCCGCTGCGTTGCTCGGCCAGAAGGACGGCATCGTCGATCCCCTGCTCCGGAAGATCG
GGGCAGACGTGAAGCTGTTCGCCGCGCGGCTCGGCGAGGCGCTCCAGAAGCTGCCCCGCATGCAGGGGGGCGAGAGCGCG
ATGCTGGGCCAGCGGCTGCTCAAGACTTTCGACAAGGCCGAGGACGAGGCCAAGTCCCTCAAGGACGAGTTCATCTCCTC
GGAGCACCTGCTGCTCGCGCTCACGCACGACAAGGGCGCGGTGGGCGAGGTGATGAAGTCCTCGGGCGTCACGAGGGAGC
GCGTGCTGTCCGGACTCAAGGAGGTCCGGGGCTCCGGGCGCGTGACGAGCCAGGACGCCGAGGCGACCTACCAGGCGCTG
GAGAAGTACGGCCGCGACCTCACAGAGGCGGCGCGCTCCGGCAAGCTCGACCCCGTCATCGGCCGTGACGAGGAGATCCG
CCGGTGCGTCCAGGTGCTGAGCCGGCGCACCAAGAACAACCCGGTGCTCATCGGCGAGCCCGGCGTGGGCAAGACGGCCA
TCGCGGAAGGACTGGCGCGGCGCATCGTCGATGGCGACGTGCCGGAGGGCCTGAAGAACAAGCGCCTGGTGTCCCTGGAT
TTGGGCGCCATGGTGGCCGGCGCGAAGTACCGCGGCGAGTTCGAGGAGCGCCTCAAGGCCGTCCTCAAGGAGATTGCCGA
CGCCGCGGGCGAGGTCATCCTCTTCATCGACGAGCTCCACACGCTGGTGGGCGCGGGCAAGGCCGAAGGGGCCATGGACG
CGGGCAACATGCTCAAGCCGGCGCTGGCGCGCGGCGAGCTGCACTGCATCGGCGCCACCACGCTGGACGAGTACCGCAAG
CACATCGAGAAGGACGCCGCGCTGGAGCGGCGCTTCCAGCCCGTCCTGGTGGGCGAGCCGAGCGTGCACGACACCATCAG
CATCCTCCGCGGCCTGAAGGAGCGCTACGAGGTGCACCACGGCGTGCGCATCCAGGACAACGCCCTGGTGGCCGCCGCCA
CGCTGAGCCACCGCTACATCGCGGACCGGTTCCTGCCGGACAAGGCCATCGACCTGGTCGACGAGGCCTCCAGCCGCCTG
CGCATCGAAATCGACTCCATGCCCACGGAGCTGGACGACGTGCGCCGGAAGATGACGCAGCTCCAGATTGAGCGGGAGGG
CTTGCGCAAGGAGACGGACCCGCACTCGCAGGAGCGCCTGGGCCAGATTGAGAAGGAGCTGGCCAACCTGAGCGAGAAGT
TCAACGCGCTCAAGGTGCACTGGGACGCGGAGAAGACGGCCATTGGCGCCATCCGCAGCCTGAAGGAGAAGCAGGAGAAG
GCGAAGAACGACCAGGCTGCGGCCGAGCGTCAGGGCGACCTGAACCGCGCGGCGGAGCTGAAGTTCGGCGTCATCCCCTC
GCTCGACAAGGAGCTGAAGGCGCAGAACGAGAAGCTGGCCGAGCTGCAGAAGAACCAGAAGTTCCTCAAGGAGGAGGTCG
ACGCGGAGGACATCGCCCAGGTGGTGGCCAAGTGGACGGGCATCCCCGTCTCGCGGCTGATGGAGGGCGAGGTCCAGAAG
CTGGTCCACATGGAGGACCGGTTGGCGAACCGGGTGATTGGCCAGCGCAGCGCCATCGAGGCGGTGTCCAACGCCGTGCG
CCGCGCGCGCAGCGGACTGCAGGACCCCAACCGCCCCATCGGTTCGTTCATCTTCCTGGGCCCCACGGGCGTGGGCAAGA
CGGAGACGGCCAAGGCGCTGGCGGAGTTCCTCTTCGATGATGACTCGGCCATGGTCCGCATCGACATGTCCGAGTACATG
GAGAAGCACTCCGTGGCCCGGCTGGTCGGCGCGCCTCCGGGGTACGTCGGCTACGAGGAGGGCGGCCAGCTCACCGAGGC
GGTGCGCCGGCGGCCGTACACGGTGGTCCTCTTCGACGAAATCGAGAAGGCGCACCACGACGTCTTCAATGTGCTGCTCC
AGATTCTCGACGAGGGCCGGCTGACGGACAGCCAGGGCCGCACGGTGGACTTCAAGAACACGGTGCTCATCCTGACGTCC
AACATCGGCTCGCAGGACATCCAGGCCGGCATGGCGGGCAAGGAGGAGCTGGACGAGCGCACGCGCAACGAGGTGATGGA
CGCGCTGCGCGCGCACTTCCGGCCGGAGTTCCTCAACCGCGTGGACGAGATCGTCATCTTCGAGCCGCTGCGGAAGAAGG
ACATCTACCGCATCGTGGACCTGCAGTTGGCGCGGCTGTCCAAGCTGCTGGCCGACAAGCGGCTGACGCTGGAGCTGACG
GAGAAGGCGCGCGAGCTGCTCGCCGAGCGCGGCTACGACCCGACGTACGGCGCGCGGCCCCTGAAGCGCGCGGTACAGAA
GAACCTGTTGGACCCGCTGGCCCTCAAGGTCCTGGGCGGCGAGTTCGTCCCGGGCGACCACATCCAGGCGGATGCGGGCC
CGGACGGGCTCACCTTCGCCAAGGTGCTGGTGGACACCTCGAAGGACGTGAAGCGCTCGGCCTAG

Upstream 100 bases:

>100_bases
AAGCAGGTAGTTACCAGGAGTCCAAACTATTCCAGACAAGCGGAAACGTCGCGCCACGTGCGCTGCTTGCCAAGGGGTGG
CCGACTCTTACGTTGGAGGC

Downstream 100 bases:

>100_bases
CCCGGGCGTCCACGGATGTGCCTCGGCCCGGCGTCATGGCTTGACGCCGGGCCGCCTCCGCGCGAAGAGCCCGGCCATGA
AGCCCTGGGAGACGCTGGAG

Product: ATP-dependent chaperone protein ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 874; Mature: 874

Protein sequence:

>874_residues
MRLDKYTVKAQEAIHEGQSLARRADNPQYEPEHLAAALLGQKDGIVDPLLRKIGADVKLFAARLGEALQKLPRMQGGESA
MLGQRLLKTFDKAEDEAKSLKDEFISSEHLLLALTHDKGAVGEVMKSSGVTRERVLSGLKEVRGSGRVTSQDAEATYQAL
EKYGRDLTEAARSGKLDPVIGRDEEIRRCVQVLSRRTKNNPVLIGEPGVGKTAIAEGLARRIVDGDVPEGLKNKRLVSLD
LGAMVAGAKYRGEFEERLKAVLKEIADAAGEVILFIDELHTLVGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYRK
HIEKDAALERRFQPVLVGEPSVHDTISILRGLKERYEVHHGVRIQDNALVAAATLSHRYIADRFLPDKAIDLVDEASSRL
RIEIDSMPTELDDVRRKMTQLQIEREGLRKETDPHSQERLGQIEKELANLSEKFNALKVHWDAEKTAIGAIRSLKEKQEK
AKNDQAAAERQGDLNRAAELKFGVIPSLDKELKAQNEKLAELQKNQKFLKEEVDAEDIAQVVAKWTGIPVSRLMEGEVQK
LVHMEDRLANRVIGQRSAIEAVSNAVRRARSGLQDPNRPIGSFIFLGPTGVGKTETAKALAEFLFDDDSAMVRIDMSEYM
EKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYTVVLFDEIEKAHHDVFNVLLQILDEGRLTDSQGRTVDFKNTVLILTS
NIGSQDIQAGMAGKEELDERTRNEVMDALRAHFRPEFLNRVDEIVIFEPLRKKDIYRIVDLQLARLSKLLADKRLTLELT
EKARELLAERGYDPTYGARPLKRAVQKNLLDPLALKVLGGEFVPGDHIQADAGPDGLTFAKVLVDTSKDVKRSA

Sequences:

>Translated_874_residues
MRLDKYTVKAQEAIHEGQSLARRADNPQYEPEHLAAALLGQKDGIVDPLLRKIGADVKLFAARLGEALQKLPRMQGGESA
MLGQRLLKTFDKAEDEAKSLKDEFISSEHLLLALTHDKGAVGEVMKSSGVTRERVLSGLKEVRGSGRVTSQDAEATYQAL
EKYGRDLTEAARSGKLDPVIGRDEEIRRCVQVLSRRTKNNPVLIGEPGVGKTAIAEGLARRIVDGDVPEGLKNKRLVSLD
LGAMVAGAKYRGEFEERLKAVLKEIADAAGEVILFIDELHTLVGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYRK
HIEKDAALERRFQPVLVGEPSVHDTISILRGLKERYEVHHGVRIQDNALVAAATLSHRYIADRFLPDKAIDLVDEASSRL
RIEIDSMPTELDDVRRKMTQLQIEREGLRKETDPHSQERLGQIEKELANLSEKFNALKVHWDAEKTAIGAIRSLKEKQEK
AKNDQAAAERQGDLNRAAELKFGVIPSLDKELKAQNEKLAELQKNQKFLKEEVDAEDIAQVVAKWTGIPVSRLMEGEVQK
LVHMEDRLANRVIGQRSAIEAVSNAVRRARSGLQDPNRPIGSFIFLGPTGVGKTETAKALAEFLFDDDSAMVRIDMSEYM
EKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYTVVLFDEIEKAHHDVFNVLLQILDEGRLTDSQGRTVDFKNTVLILTS
NIGSQDIQAGMAGKEELDERTRNEVMDALRAHFRPEFLNRVDEIVIFEPLRKKDIYRIVDLQLARLSKLLADKRLTLELT
EKARELLAERGYDPTYGARPLKRAVQKNLLDPLALKVLGGEFVPGDHIQADAGPDGLTFAKVLVDTSKDVKRSA
>Mature_874_residues
MRLDKYTVKAQEAIHEGQSLARRADNPQYEPEHLAAALLGQKDGIVDPLLRKIGADVKLFAARLGEALQKLPRMQGGESA
MLGQRLLKTFDKAEDEAKSLKDEFISSEHLLLALTHDKGAVGEVMKSSGVTRERVLSGLKEVRGSGRVTSQDAEATYQAL
EKYGRDLTEAARSGKLDPVIGRDEEIRRCVQVLSRRTKNNPVLIGEPGVGKTAIAEGLARRIVDGDVPEGLKNKRLVSLD
LGAMVAGAKYRGEFEERLKAVLKEIADAAGEVILFIDELHTLVGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYRK
HIEKDAALERRFQPVLVGEPSVHDTISILRGLKERYEVHHGVRIQDNALVAAATLSHRYIADRFLPDKAIDLVDEASSRL
RIEIDSMPTELDDVRRKMTQLQIEREGLRKETDPHSQERLGQIEKELANLSEKFNALKVHWDAEKTAIGAIRSLKEKQEK
AKNDQAAAERQGDLNRAAELKFGVIPSLDKELKAQNEKLAELQKNQKFLKEEVDAEDIAQVVAKWTGIPVSRLMEGEVQK
LVHMEDRLANRVIGQRSAIEAVSNAVRRARSGLQDPNRPIGSFIFLGPTGVGKTETAKALAEFLFDDDSAMVRIDMSEYM
EKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYTVVLFDEIEKAHHDVFNVLLQILDEGRLTDSQGRTVDFKNTVLILTS
NIGSQDIQAGMAGKEELDERTRNEVMDALRAHFRPEFLNRVDEIVIFEPLRKKDIYRIVDLQLARLSKLLADKRLTLELT
EKARELLAERGYDPTYGARPLKRAVQKNLLDPLALKVLGGEFVPGDHIQADAGPDGLTFAKVLVDTSKDVKRSA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=338, Percent_Identity=36.9822485207101, Blast_Score=221, Evalue=4e-57,
Organism=Escherichia coli, GI1788943, Length=857, Percent_Identity=57.8763127187865, Blast_Score=988, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=319, Percent_Identity=45.141065830721, Blast_Score=282, Evalue=6e-77,
Organism=Saccharomyces cerevisiae, GI6320464, Length=696, Percent_Identity=56.3218390804598, Blast_Score=779, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=852, Percent_Identity=44.7183098591549, Blast_Score=703, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 97020; Mature: 97020

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDKYTVKAQEAIHEGQSLARRADNPQYEPEHLAAALLGQKDGIVDPLLRKIGADVKLF
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHH
AARLGEALQKLPRMQGGESAMLGQRLLKTFDKAEDEAKSLKDEFISSEHLLLALTHDKGA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCH
VGEVMKSSGVTRERVLSGLKEVRGSGRVTSQDAEATYQALEKYGRDLTEAARSGKLDPVI
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCC
GRDEEIRRCVQVLSRRTKNNPVLIGEPGVGKTAIAEGLARRIVDGDVPEGLKNKRLVSLD
CCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
LGAMVAGAKYRGEFEERLKAVLKEIADAAGEVILFIDELHTLVGAGKAEGAMDAGNMLKP
HHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCCCCCCHHHHH
ALARGELHCIGATTLDEYRKHIEKDAALERRFQPVLVGEPSVHDTISILRGLKERYEVHH
HHHCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHC
GVRIQDNALVAAATLSHRYIADRFLPDKAIDLVDEASSRLRIEIDSMPTELDDVRRKMTQ
CCEEECCCEEEHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHH
LQIEREGLRKETDPHSQERLGQIEKELANLSEKFNALKVHWDAEKTAIGAIRSLKEKQEK
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHH
AKNDQAAAERQGDLNRAAELKFGVIPSLDKELKAQNEKLAELQKNQKFLKEEVDAEDIAQ
HCCHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VVAKWTGIPVSRLMEGEVQKLVHMEDRLANRVIGQRSAIEAVSNAVRRARSGLQDPNRPI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC
GSFIFLGPTGVGKTETAKALAEFLFDDDSAMVRIDMSEYMEKHSVARLVGAPPGYVGYEE
CCEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCC
GGQLTEAVRRRPYTVVLFDEIEKAHHDVFNVLLQILDEGRLTDSQGRTVDFKNTVLILTS
CCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEC
NIGSQDIQAGMAGKEELDERTRNEVMDALRAHFRPEFLNRVDEIVIFEPLRKKDIYRIVD
CCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEECCHHHHHHHHHHH
LQLARLSKLLADKRLTLELTEKARELLAERGYDPTYGARPLKRAVQKNLLDPLALKVLGG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCC
EFVPGDHIQADAGPDGLTFAKVLVDTSKDVKRSA
CCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure
MRLDKYTVKAQEAIHEGQSLARRADNPQYEPEHLAAALLGQKDGIVDPLLRKIGADVKLF
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHH
AARLGEALQKLPRMQGGESAMLGQRLLKTFDKAEDEAKSLKDEFISSEHLLLALTHDKGA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCH
VGEVMKSSGVTRERVLSGLKEVRGSGRVTSQDAEATYQALEKYGRDLTEAARSGKLDPVI
HHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCC
GRDEEIRRCVQVLSRRTKNNPVLIGEPGVGKTAIAEGLARRIVDGDVPEGLKNKRLVSLD
CCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
LGAMVAGAKYRGEFEERLKAVLKEIADAAGEVILFIDELHTLVGAGKAEGAMDAGNMLKP
HHHHHHCCHHCCCHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCCCCCCHHHHH
ALARGELHCIGATTLDEYRKHIEKDAALERRFQPVLVGEPSVHDTISILRGLKERYEVHH
HHHCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHC
GVRIQDNALVAAATLSHRYIADRFLPDKAIDLVDEASSRLRIEIDSMPTELDDVRRKMTQ
CCEEECCCEEEHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHH
LQIEREGLRKETDPHSQERLGQIEKELANLSEKFNALKVHWDAEKTAIGAIRSLKEKQEK
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHH
AKNDQAAAERQGDLNRAAELKFGVIPSLDKELKAQNEKLAELQKNQKFLKEEVDAEDIAQ
HCCHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VVAKWTGIPVSRLMEGEVQKLVHMEDRLANRVIGQRSAIEAVSNAVRRARSGLQDPNRPI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC
GSFIFLGPTGVGKTETAKALAEFLFDDDSAMVRIDMSEYMEKHSVARLVGAPPGYVGYEE
CCEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCC
GGQLTEAVRRRPYTVVLFDEIEKAHHDVFNVLLQILDEGRLTDSQGRTVDFKNTVLILTS
CCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEC
NIGSQDIQAGMAGKEELDERTRNEVMDALRAHFRPEFLNRVDEIVIFEPLRKKDIYRIVD
CCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEECCHHHHHHHHHHH
LQLARLSKLLADKRLTLELTEKARELLAERGYDPTYGARPLKRAVQKNLLDPLALKVLGG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCC
EFVPGDHIQADAGPDGLTFAKVLVDTSKDVKRSA
CCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA